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1. 发明授权

US06876085B1 Signal layer interconnect using tapered traces 失效
标题翻译：使用锥形迹线的信号层互连
公开(公告)号：US06876085B1
公开(公告)日：2005-04-05
申请号：US10139982
申请日：2002-05-07
申请人： Martin R. Handforth , John J. Stankus
发明人： Martin R. Handforth , John J. Stankus
IPC分类号： H01R9/05 , H05K1/00 , H05K1/02 , H05K1/11 , H05K3/34 , H05K3/36 , H01L23/48 , H01R9/00 , H01R12/04
CPC分类号： H05K1/117 , H01R9/05 , H01R12/52 , H05K1/0219 , H05K1/0237 , H05K1/0298 , H05K3/3405 , H05K3/361 , H05K2201/0919 , H05K2201/09727 , H05K2201/09845 , H05K2201/1034
摘要： An interconnection device has a substrate that includes a conductive trace having an exposed portion at an edge of the substrate. The exposed portion is tapered toward the edge of the substrate. The exposed portion is provided for direct physical contact with a second conductive trace exposed at an edge of a second substrate. A high frequency direct electrical interconnection is thereby provided that reduces the disadvantageous effects of lateral, longitudinal, and co-planar misalignment between the conductive traces.
摘要翻译：互连器件具有衬底，该衬底包括在衬底的边缘处具有暴露部分的导电迹线。暴露部分朝向基板的边缘逐渐变细。暴露部分被提供用于与暴露在第二基底的边缘处的第二导电迹线直接物理接触。由此提供了高频直接电互连，其减少了导电迹线之间的横向，纵向和共平面的未对准的不利影响。

2. 发明授权

US06411758B1 Method and apparatus for aligning a waveguide to a device 有权
标题翻译：用于将波导对准设备的方法和设备
公开(公告)号：US06411758B1
公开(公告)日：2002-06-25
申请号：US09494457
申请日：2000-01-31
申请人： John J. Stankus
发明人： John J. Stankus
IPC分类号： G02B630
CPC分类号： G02B6/422 , G02B6/4206 , G02B6/4212 , G02B6/4225
摘要： An apparatus which aligns a fiber core to a detector on an integrated circuit has a transmission material connecting them which steers the light provided through the fiber core to the detector even in the case of misalignment. The transmission material chosen has a characteristic of being able to have the spatial distribution of its index of refraction altered by electrical means. In this case, an electric field is applied in the area surrounding the path from the fiber core to the detector. Thus, even if the fiber core is not aligned to the detector, the light will be directed from the fiber core to the detector due to the path being surrounded by a lower index of refraction than the path itself. Thus, there is very little loss due to misalignment between the fiber core and the detector.
摘要翻译：将纤维芯与集成电路上的检测器对准的装置具有将它们连接的传输材料，即使在未对准的情况下也将通过纤维芯提供的光转向检测器。所选择的透射材料具有能够通过电气方式改变其折射率的空间分布的特征。在这种情况下，在从光纤芯到检测器的路径周围的区域中施加电场。因此，即使光纤芯不与检测器对准，由于路径被路径自身折射率较低的折射线包围，所以光将从光纤芯线引导到检测器。因此，由于纤维芯和检测器之间的未对准，损失非常小。

3. 发明授权

US4919970A Solder deposition control 失效
标题翻译：焊接沉积控制
公开(公告)号：US4919970A
公开(公告)日：1990-04-24
申请号：US907265
申请日：1986-09-15
申请人： Karl G. Hoebener , John J. Stankus
发明人： Karl G. Hoebener , John J. Stankus
IPC分类号： B23K3/06 , H05K3/12 , H05K3/34
CPC分类号： H05K3/1233 , H05K3/12 , H05K2201/09572 , H05K2203/0139 , H05K2203/163
摘要： A technique for one step solder application through a mask to a printed circuit board (PCB) having pads for surface mountable components and through holes for a leaded components is disclosed wherein the amount of solder deposited on the pads and in the holes is simultaneously, independently controlled as a function of mask thickness, blade hardness and blade to mask angle.

4. 发明授权

US09295663B2 Drug coated balloon with in-situ formed drug containing microspheres 有权
标题翻译：药物包衣球囊与原位形成药物含微球
公开(公告)号：US09295663B2
公开(公告)日：2016-03-29
申请号：US12836529
申请日：2010-07-14
申请人： Stephen D. Pacetti , John J. Stankus
发明人： Stephen D. Pacetti , John J. Stankus
IPC分类号： A61F13/00 , A61K31/337 , A61K31/436 , A61K31/675 , A61L29/08 , A61L29/16 , A61L31/10 , A61L31/16 , A61M25/10
CPC分类号： A61K31/337 , A61K31/436 , A61K31/675 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/606 , A61L2420/02 , A61L2420/06 , A61M25/1029 , A61M2025/1031 , A61M2025/105
摘要： The current invention relates to methods of forming a coating that involves the in-situ formation of drug microspheres. The coating may be applied to a medical device, such as a catheter balloon or a stent. Coated devices and methods of treatment therewith are also encompassed within the embodiments of the present invention.
摘要翻译：本发明涉及形成涉及药物微球原位形成的涂层的方法。涂层可以施加到诸如导管球囊或支架的医疗装置上。涂覆的装置及其处理方法也包括在本发明的实施方案中。

5. 发明申请

US20130261723A1 Treatment Of Diabetic Patients With A Drug Eluting Stent And A Drug Coated Balloon 审中-公开
标题翻译：治疗糖尿病患者药物洗脱支架和药物涂层气球
公开(公告)号：US20130261723A1
公开(公告)日：2013-10-03
申请号：US13436662
申请日：2012-03-30
申请人： John J. Stankus , Syed F.A. Hossainy , Daniel L. Cox , Paul M. Consigny
发明人： John J. Stankus , Syed F.A. Hossainy , Daniel L. Cox , Paul M. Consigny
IPC分类号： A61F2/82 , A61F2/84 , A61M25/10
CPC分类号： A61K31/427 , A61F2/958 , A61F2250/0067 , A61K45/06 , A61L31/10 , A61L31/16 , A61L2300/41 , A61L2300/416 , A61L2300/61 , A61M25/104 , A61M2025/0183 , A61M2025/105 , A61K2300/00
摘要： Embodiments of the present invention include methods for the treatment, prevention, or amelioration of vascular disease and/or disorder in diabetic patients. The methods include implantation of a stent including a drug, and the use of a drug coated balloon. The DES may be a DES having a metal body and a coating including the drug, or a bioabsorbable stent with drug in the body of the stent, in a coating on the stent, or both in the body of the stent and in a coating on the stent.
摘要翻译：本发明的实施方案包括治疗，预防或改善糖尿病患者血管疾病和/或病症的方法。所述方法包括植入包括药物的支架以及使用药物涂覆的气囊。 DES可以是具有金属体和包含药物的涂层，或者在支架的体内具有药物的生物可吸收支架，在支架的涂层中，或者在支架的主体中以及涂层中的涂层支架

6. 发明申请

US20120015019A1 Drug Coated Balloon With In-Situ Formed Drug Containing Microspheres 有权
标题翻译：含有微球的原位形成药物的药物涂层气球
公开(公告)号：US20120015019A1
公开(公告)日：2012-01-19
申请号：US12836529
申请日：2010-07-14
申请人： Stephen D. Pacetti , John J. Stankus
发明人： Stephen D. Pacetti , John J. Stankus
IPC分类号： A61M25/10 , A61L29/16 , A61K31/675 , A61P9/10 , A61K31/337 , A61K31/436
CPC分类号： A61K31/337 , A61K31/436 , A61K31/675 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/606 , A61L2420/02 , A61L2420/06 , A61M25/1029 , A61M2025/1031 , A61M2025/105
摘要： The current invention relates to methods of forming a coating that involves the in-situ formation of drug microspheres. The coating may be applied to a medical device, such as a catheter balloon or a stent. Coated devices and methods of treatment therewith are also encompassed within the embodiments of the present invention.
摘要翻译：本发明涉及形成涉及药物微球原位形成的涂层的方法。涂层可以施加到诸如导管球囊或支架的医疗装置上。涂覆的装置及其处理方法也包括在本发明的实施方案中。

7. 发明授权

US08038991B1 High-viscosity hyaluronic acid compositions to treat myocardial conditions 有权
标题翻译：高粘度透明质酸组合物治疗心肌病症
公开(公告)号：US08038991B1
公开(公告)日：2011-10-18
申请号：US11933922
申请日：2007-11-01
申请人： John J. Stankus , Eugene Michal , Mikael Trollsas , Brandon Katz , Shubhayu Basu
发明人： John J. Stankus , Eugene Michal , Mikael Trollsas , Brandon Katz , Shubhayu Basu
IPC分类号： C12N5/00
CPC分类号： A61K31/00 , A61K9/0024 , A61K31/728 , A61K31/78 , A61K31/79 , A61K35/16 , A61K35/28 , A61K35/34 , A61K35/35 , A61K38/40 , A61K45/06 , A61K47/36 , A61L27/26 , A61L27/3804 , A61L27/3839 , A61L2430/20 , A61K2300/00 , C08L5/08
摘要： Embodiments of single component bioscaffolding systems formed of a hydrogel such as hyaluronic acid or salt thereof are described. The hyaluronic acid or salt thereof may be dissolved in a buffer, plasma, or combination thereof to minimize adverse immunogenic responses when applied to a treatment site. Additionally, the hydrogel component includes stem cells to facilitate angiogenesis or facilitate tissue repair and/or regeneration of ischemic tissue, particularly in compromised cardiac tissue. The bioscaffolding may also be formed on a stent or a cardiac medical device.
摘要翻译：描述了由诸如透明质酸或其盐的水凝胶形成的单组分生物支架系统的实施方案。透明质酸或其盐可以溶解在缓冲液，血浆或其组合中，以在施用于治疗部位时使不利的免疫原性反应最小化。此外，水凝胶组分包括促进血管发生的干细胞，或促进缺血组织的组织修复和/或再生，特别是在受损的心脏组织中。生物支架也可以形成在支架或心脏医疗装置上。

8. 发明申请

US20100330147A1 Drug Delivery Compositions Including Nanoshells For Triggered Drug Release 有权
标题翻译：包括用于触发药物释放的纳米壳的药物递送成分
公开(公告)号：US20100330147A1
公开(公告)日：2010-12-30
申请号：US12493112
申请日：2009-06-26
申请人： Syed F. A. Hossainy , John J. Stankus , Dariush Davalian
发明人： Syed F. A. Hossainy , John J. Stankus , Dariush Davalian
IPC分类号： A61F2/00 , A61K9/16
CPC分类号： A61K9/0009 , A61K9/1641 , A61K9/1647 , A61K9/5031 , A61K9/5146 , A61K9/5153 , A61L27/54 , A61L29/16 , A61L31/16 , A61L2300/45 , A61L2300/602 , A61L2400/12 , A61M25/0045 , A61M2025/0057 , A61M2025/105 , Y10S977/773 , Y10S977/906
摘要： The current invention is directed to compositions comprising a plurality of particles including nanoshells or a medical device with a coating including nanoshells allowing for triggered drug release. Methods of treatment with such compositions are also included.
摘要翻译：本发明涉及包含多个包括纳米壳的颗粒的组合物或具有包含允许触发的药物释放的纳米壳的涂层的医疗装置。还包括用这些组合物处理的方法。

9. 发明申请

US20080208323A1 Bioerodible wraps and uses therefor 有权
标题翻译：生物蚀刻包装和用途
公开(公告)号：US20080208323A1
公开(公告)日：2008-08-28
申请号：US12022430
申请日：2008-01-30
申请人： Mohammed S. El-Kurdi , Yi Hong , Lorenzo Soletti , John J. Stankus , David A. Vorp , William R. Wagner
发明人： Mohammed S. El-Kurdi , Yi Hong , Lorenzo Soletti , John J. Stankus , David A. Vorp , William R. Wagner
IPC分类号： A61F2/06 , D01D5/00
CPC分类号： A61F2/06 , A61F2/07 , A61F2210/0004 , A61F2210/0076 , A61F2240/001 , A61F2250/0067 , A61L27/18 , A61L27/34 , A61L27/3625 , A61L27/3683 , A61L27/3691 , A61L27/3804 , A61L27/3826 , A61L27/507 , A61L27/54 , A61L27/58 , A61L2300/414 , A61L2300/604 , A61L2430/22 , C12N5/0068 , C12N2533/40 , D01D5/0007 , D01D5/0076 , D10B2331/10 , D10B2401/12 , D10B2509/06 , C08L67/04
摘要： A tubular tissue graft device is provided comprising a tubular tissue and a restrictive fiber matrix of a bioerodible polymer about a circumference of the tubular tissue. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. Also provided is method of preparing a tubular graft comprising depositing a fiber matrix of a bioerodible polymer about a perimeter of a tubular tissue to produce a tubular tissue graft device. A cardiac bypass method comprising bypassing a coronary artery with a tubular tissue graft device comprising a vein and a restrictive fiber matrix of a bioerodible polymer about a circumference of the vein also is provided.
摘要翻译：提供了一种管状组织移植装置，其包括管状组织和围绕管状组织的圆周的生物可蚀解聚合物的限制性纤维基质。基质可以电纺到管状组织上。在一个实施例中，管状组织来自静脉，例如隐静脉，可用作动脉移植物，例如但不限于冠状动脉旁路手术。还提供了制备管状移植物的方法，其包括围绕管状组织的周边沉积生物可蚀解聚合物的纤维基质以产生管状组织移植装置。还提供了一种包括绕管冠状动脉的心脏旁路方法，所述管状组织移植装置包括静脉和围绕静脉周围的生物可蚀解聚合物的限制性纤维基质。

10. 发明授权

US06417077B1 Edge growth heteroepitaxy processes with reduced lattice mismatch strain between a deposited semiconductor material and a semiconductor substrate 失效
标题翻译：在沉积的半导体材料和半导体衬底之间具有减小的晶格失配应变的边缘生长异质外延过程
公开(公告)号：US06417077B1
公开(公告)日：2002-07-09
申请号：US09499285
申请日：2000-02-07
申请人： John J. Stankus
发明人： John J. Stankus
IPC分类号： H01L2120
CPC分类号： H01L21/02381 , H01L21/02538 , H01L21/02546 , H01L21/02639 , H01L21/02647 , H01L21/02658
摘要： Semiconductor devices that include mismatched lattice crystal interfaces are produced by edge growth heteroepitaxy from a crystal with a small surface area to decrease crystal mismatch strain, achieving a crystal with reduced displacement faults. Mismatched crystal lattices are also deposited on a deformable thin membrane of semiconductor material to reduce strain in growing crystal and to reduce displacement faults to achieve a monolithic crystal structure.
摘要翻译：包括不匹配晶格晶界面的半导体器件由具有小表面积的晶体的边缘生长异质外延产生，以减少晶体失配应变，从而获得具有减少的位移缺陷的晶体。不均匀的晶格也沉积在半导体材料的可变形薄膜上，以减少生长晶体中的应变，并减少位移缺陷以实现单片晶体结构。

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