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    • 1. 发明授权
    • Fluid cocamide monoethanolamide concentrates and methods of preparation
    • 流体椰油酰胺单乙醇酰胺浓缩物及其制备方法
    • US08937102B2
    • 2015-01-20
    • US13634081
    • 2011-02-26
    • John F. HesselStephen F. GrossAnna Kvecher
    • John F. HesselStephen F. GrossAnna Kvecher
    • A61Q19/00A61K8/34A61K8/42C11D1/52
    • A61K8/42A61K8/345A61Q19/00
    • The invention is drawn to fluid concentrate formulations of fatty acid monoethanolamides comprising (a) about 71-76% by weight of one or more C8-C22 fatty acid monoethanolamides, (b) about 15-17% by weight of water, and (c) about 10-12% by weight of one or more hydrotropes, based on the fluid formulation, wherein the fluid formulation is homogeneous, pumpable and color stable at a temperature of less than 55° C. A preferred embodiment is drawn to fluid concentrate formulations of cocamide monoethanolamide (CMEA) consisting of (a) about 71-76% by weight of CMEA, (b) about 15-17% by weight of water, and (c) about 10-12% by weight of glycerol, based on the fluid formulation. Methods of preparing the fluid concentrate formulations mulations are also disclosed. The fluid concentrate formulations of fatty acid monoethanolamides are useful in the preparation of cosmetic and pharmaceutical compositions.
    • 本发明涉及脂肪酸单乙醇酰胺的流体浓缩物制剂,其包含(a)约71-76重量%的一种或多种C 8 -C 22脂肪酸单乙醇酰胺,(b)约15-17重量%的水,和(c )约10-12重量%的一种或多种水溶助长剂,基于流体配方,其中流体配方在低于55℃的温度下是均匀的,可泵送的和颜色稳定的。优选的实施方案被吸引到流体浓缩物配方 由(a)约71-76重量%的CMEA组成的椰油酰胺单乙醇酰胺(CMEA),(b)约15-17重量%的水,和(c)约10-12重量%的甘油,基于 流体配方。 还公开了制备流体浓缩物配方的方法。 脂肪酸单乙醇酰胺的流体浓缩物制剂可用于制备化妆品和药物组合物。
    • 3. 发明授权
    • Alkyl polyglycosides having improved aesthetic and tactile properties
    • 烷基聚糖苷具有改善的美学和触觉性能
    • US5567808A
    • 1996-10-22
    • US338701
    • 1994-11-10
    • Sureshchandra G. DesaiJohn F. HesselAllen D. UrferCharles B. AllenStephen A. Fischer
    • Sureshchandra G. DesaiJohn F. HesselAllen D. UrferCharles B. AllenStephen A. Fischer
    • A61K8/60A61Q5/02A61Q19/10C07G3/00C07H15/04C11D1/66C11D3/20C07H15/00C07H15/02
    • A61K8/604A61Q19/10A61Q5/02C07H15/04C11D1/662A61K2800/596
    • A composition and process for enhancing the aesthetic and tactile properties of an alkyl polyglycoside involving combining a first alkyl polyglycoside having the general formula I:RO(Z).sub.a (I)wherein R is a monovalent organic radical having from about 8 to about 18 carbon atoms; Z is a saccharide residue having 5 or 6 carbon atoms; and a is a number having a value from about 1 to about 6, with an additive selected from the group consisting of C.sub.6 -C.sub.10 alkyl sulfates, unsaturated aliphatic carboxylic acids including hydroxy-substituted derivatives thereof or their salts, unsaturated aliphatic sorbitan esters, C.sub.8 -C.sub.36 branched aliphatic dicarboxylic acids, C.sub.6 -C.sub.54 branched aliphatic tri-carboxylic acids, alkyl sulfosuccinates, a second alkyl polyglycoside having an alkyl group with from 4 to 10 carbon atoms, alkyl alkoxylates, alkyl and aryl phosphate esters, branched aliphatic carboxylic acids, unsaturated alcohols, Guerbet alcohols, alkoxylated C 6 to C 18 alkyl polyglycosides, alkoxylated penterythritol, alkoxylated penterythritol esters, alkyl and aryl sulfonates, alkyl sulfonates, alkenyl sulfonates, alkyl amino carboxylates or imino dicarboxylates, betaines, carboxylated imidazoline derivatives, carboxylate surfactants, and mixtures thereof.
    • 一种用于增强烷基多糖苷的美学和触觉性质的组合物和方法,包括组合具有通式I的第一烷基多糖苷:RO(Z)a(I)其中R是具有约8至约18个碳原子的一价有机基团 原子 Z是具有5或6个碳原子的糖残基; 并且a是具有约1至约6的值的数,其中选自C 6 -C 10烷基硫酸盐,包括其羟基取代的衍生物的不饱和脂族羧酸或其盐,不饱和脂族脱水山梨糖醇酯,C8 -C 36支链脂肪族二羧酸,C6-C54支链脂肪族三羧酸,烷基磺基琥珀酸盐,具有4-10个碳原子的烷基的第二烷基多糖苷,烷基烷氧基化物,烷基和芳基磷酸酯,支链脂族羧酸, 不饱和醇,格伯特醇,烷氧基化C 6至C 18烷基多糖苷,烷氧基化季戊四醇,烷氧基化季戊四醇酯,烷基和芳基磺酸盐,烷基磺酸盐,烯基磺酸盐,烷基氨基羧酸盐或亚氨基二羧酸盐,甜菜碱,羧化咪唑啉衍生物,羧酸盐表面活性剂和 其混合物。