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1. 发明授权

US09277880B2 Multi-stream data collection system for noninvasive measurement of blood constituents 有权
标题翻译：用于非侵入性测量血液成分的多流数据收集系统
公开(公告)号：US09277880B2
公开(公告)日：2016-03-08
申请号：US12829352
申请日：2010-07-01
申请人： Jeroen Poeze , Marcelo Lamego , Sean Merritt , Cristiano Dalvi , Hung Vo , Johannes Bruinsma , Ferdyan Lesmana , Massi Joe E. Kiani
发明人： Jeroen Poeze , Marcelo Lamego , Sean Merritt , Cristiano Dalvi , Hung Vo , Johannes Bruinsma , Ferdyan Lesmana , Massi Joe E. Kiani
IPC分类号： A61B5/1455 , A61B5/145 , A61B5/00
CPC分类号： A61B5/1455 , A61B5/14532 , A61B5/14546 , A61B5/14552 , A61B5/6816 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/6843 , A61B2562/0233 , A61B2562/04 , A61B2562/046 , A61B2562/146
摘要： The present disclosure relates to noninvasive methods, devices, and systems for measuring various blood constituents or analytes, such as glucose. In an embodiment, a light source comprises LEDs and super-luminescent LEDs. The light source emits light at least wavelengths of about 1610 nm, about 1640 nm, and about 1665 nm. In an embodiment, the detector comprises a plurality of photodetectors arranged in a special geometry comprising one of a substantially linear substantially equal spaced geometry, a substantially linear substantially non-equal spaced geometry, and a substantially grid geometry.
摘要翻译：本公开涉及用于测量各种血液成分或分析物（例如葡萄糖）的非侵入性方法，装置和系统。在一个实施例中，光源包括LED和超发光LED。光源发射至少约1610nm，约1640nm和约1665nm的波长的光。在一个实施例中，检测器包括以特殊几何形状布置的多个光电检测器，其包括基本上线性的基本相等的间隔几何形状，基本上线性的基本上不等间隔的几何形状以及基本上网格的几何形状。

2. 发明授权

US08570503B2 Heat sink for noninvasive medical sensor 有权
标题翻译：无创医疗传感器散热片
公开(公告)号：US08570503B2
公开(公告)日：2013-10-29
申请号：US13525166
申请日：2012-06-15
申请人： Hung Vo , Marcelo Lamego , Sean Merritt , Cristiano Dalvi , Johannes Bruinsma , Jeroen Poeze , Ferdyan Lesmana , Greg Olsen , Massi Joe E. Kiani
发明人： Hung Vo , Marcelo Lamego , Sean Merritt , Cristiano Dalvi , Johannes Bruinsma , Jeroen Poeze , Ferdyan Lesmana , Greg Olsen , Massi Joe E. Kiani
IPC分类号： G01J1/42
CPC分类号： A61B5/1455 , A61B5/14532 , A61B5/14546 , A61B5/14552 , A61B5/6816 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/6843 , A61B2562/0233 , A61B2562/04 , A61B2562/046 , A61B2562/146
摘要： A noninvasive physiological sensor for measuring one or more physiological parameters of a medical patient can include a heat sink that can direct heat away from the light source.
摘要翻译：用于测量医疗患者的一个或多个生理参数的无创生理传感器可以包括可以将热量从光源引导出来的散热器。

3. 发明申请

US20100030040A1 MULTI-STREAM DATA COLLECTION SYSTEM FOR NONINVASIVE MEASUREMENT OF BLOOD CONSTITUENTS 审中-公开
标题翻译：多流量数据采集系统用于非血液测量血液成分
公开(公告)号：US20100030040A1
公开(公告)日：2010-02-04
申请号：US12534827
申请日：2009-08-03
申请人： Jeroen Poeze , Marcelo Lamego , Sean Merritt , Cristiano Dalvi , Hung Vo , Johannes Bruinsma , Ferdyan Lesmana , Massi Joe E. Kiani
发明人： Jeroen Poeze , Marcelo Lamego , Sean Merritt , Cristiano Dalvi , Hung Vo , Johannes Bruinsma , Ferdyan Lesmana , Massi Joe E. Kiani
IPC分类号： A61B5/1455
CPC分类号： A61B5/1455 , A61B5/14532 , A61B5/14546 , A61B5/14552 , A61B5/6816 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/6843 , A61B2562/0233 , A61B2562/04 , A61B2562/046 , A61B2562/146
摘要： The present disclosure relates to noninvasive methods, devices, and systems for measuring various blood constituents or analytes, such as glucose. In an embodiment, a light source comprises LEDs and super-luminescent LEDs. The light source emits light at least wavelengths of about 1610 nm, about 1640 nm, and about 1665 nm. In an embodiment, the detector comprises a plurality of photodetectors arranged in a special geometry comprising one of a substantially linear substantially equal spaced geometry, a substantially linear substantially non-equal spaced geometry, and a substantially grid geometry.
摘要翻译：本公开涉及用于测量各种血液成分或分析物（例如葡萄糖）的非侵入性方法，装置和系统。在一个实施例中，光源包括LED和超发光LED。光源发射至少约1610nm，约1640nm和约1665nm的波长的光。在一个实施例中，检测器包括以特殊几何形状布置的多个光电检测器，其包括基本上线性的基本相等的间隔几何形状，基本上线性的基本上不等间隔的几何形状以及基本上网格的几何形状。

4. 发明授权

US08577431B2 Noise shielding for a noninvasive device 有权
标题翻译：非侵入性设备的噪声屏蔽
公开(公告)号：US08577431B2
公开(公告)日：2013-11-05
申请号：US12497528
申请日：2009-07-02
申请人： Marcelo Lamego , Sean Merritt , Cristiano Dalvi , Hung Vo , Johannes Bruinsma , Jeroen Poeze , Ferdyan Lesmana , Greg Olsen , Massi Joe E. Kiani
发明人： Marcelo Lamego , Sean Merritt , Cristiano Dalvi , Hung Vo , Johannes Bruinsma , Jeroen Poeze , Ferdyan Lesmana , Greg Olsen , Massi Joe E. Kiani
IPC分类号： A61B5/1455
CPC分类号： A61B5/02427 , A61B5/02416 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/14551 , A61B5/14552 , A61B5/4875 , A61B5/6816 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/6843 , A61B5/70 , A61B5/7275 , A61B2562/146
摘要： A noninvasive physiological sensor for measuring one or more physiological parameters of a medical patient can include a bump interposed between a light source and a photodetector. The bump can be placed in contact with body tissue of a patient and thereby reduce a thickness of the body tissue. As a result, an optical pathlength between the light source and the photodetector can be reduced. In addition, the sensor can include a heat sink that can direct heat away from the light source. Moreover, the sensor can include shielding in the optical path between the light source and the photodetector. The shielding can reduce noise received by the photodetector.
摘要翻译：用于测量医疗患者的一个或多个生理参数的无创生理传感器可以包括插入在光源和光电检测器之间的凸块。凸起可以放置成与患者的身体组织接触，从而减少身体组织的厚度。结果，可以减少光源和光电检测器之间的光程。此外，传感器可以包括可将热量远离光源引导的散热器。此外，传感器可以包括在光源和光电检测器之间的光路中的屏蔽。屏蔽可以降低由光电检测器接收的噪声。

5. 发明授权

US08437825B2 Contoured protrusion for improving spectroscopic measurement of blood constituents 有权
标题翻译：用于改善血液成分的光谱测量的轮廓突起
公开(公告)号：US08437825B2
公开(公告)日：2013-05-07
申请号：US12497523
申请日：2009-07-02
申请人： Cristiano Dalvi , Marcelo Lamego , Sean Merritt , Hung Vo , Johannes Bruinsma , Jeroen Poeze , Ferdyan Lesmana , Greg Olsen , Massi Joe E. Kiani
发明人： Cristiano Dalvi , Marcelo Lamego , Sean Merritt , Hung Vo , Johannes Bruinsma , Jeroen Poeze , Ferdyan Lesmana , Greg Olsen , Massi Joe E. Kiani
IPC分类号： A61B5/1455
CPC分类号： A61B5/02427 , A61B5/02416 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/14551 , A61B5/14552 , A61B5/4875 , A61B5/6816 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/6843 , A61B5/70 , A61B5/7275 , A61B2562/146
摘要： A noninvasive physiological sensor for measuring one or more physiological parameters of a medical patient can include a bump interposed between a light source and a photodetector. The bump can be placed in contact with body tissue of a patient and thereby reduce a thickness of the body tissue. As a result, an optical pathlength between the light source and the photodetector can be reduced. In addition, the sensor can include a heat sink that can direct heat away from the light source. Moreover, the sensor can include shielding in the optical path between the light source and the photodetector. The shielding can reduce noise received by the photodetector.
摘要翻译：用于测量医疗患者的一个或多个生理参数的无创生理传感器可以包括插入在光源和光电检测器之间的凸块。凸起可以放置成与患者的身体组织接触，从而减少身体组织的厚度。结果，可以减少光源和光电检测器之间的光程。此外，传感器可以包括可将热量远离光源引导的散热器。此外，传感器可以包括在光源和光电检测器之间的光路中的屏蔽。屏蔽可以降低由光电检测器接收的噪声。

6. 发明申请

US20110087083A1 ANALYTE MONITORING USING ONE OR MORE ACCELEROMETERS 有权
标题翻译：使用一个或多个加速度计分析监测
公开(公告)号：US20110087083A1
公开(公告)日：2011-04-14
申请号：US12883770
申请日：2010-09-16
申请人： Jeroen Poeze , Johannes Bruinsma , Marcelo Lamego
发明人： Jeroen Poeze , Johannes Bruinsma , Marcelo Lamego
IPC分类号： A61B5/1455
CPC分类号： A61B5/14532 , A61B5/14551 , A61B5/6838 , A61B2562/0219 , A61B2562/0233
摘要： The present disclosure relates to methods, devices, and systems for measuring a blood analyte, such as glucose. The disclosure relates more specifically to the use in such methods, devices, and systems of one or more accelerometers to aid in the collection of data, operation of the device, filtering, and other uses. In some embodiments, the accelerometers are three-dimensional accelerometers. An accelerometer can be used in conjunction with analyte monitoring that may be performed with infrared, near infrared, or other wavelength spectroscopy. The accelerometer may allow a monitoring instrument to expect noisy measurement data, indicate positioning of a measurement site for improved expected results, indicate position of the instrument, or help the user properly place or control the instrument. It may also improve analyte monitoring by providing motion information that can be used to help determine and reduce or remove movement-related signal artifacts or noise that may be present within the monitoring signal.
摘要翻译：本公开涉及用于测量诸如葡萄糖的血液分析物的方法，装置和系统。本公开更具体地涉及在一个或多个加速度计的这种方法，设备和系统中的使用，以帮助数据的收集，设备的操作，过滤和其它用途。在一些实施例中，加速度计是三维加速度计。加速度计可以与可以用红外线，近红外或其他波长光谱法进行的分析物监测结合使用。加速度计可以允许监测仪器期望噪声测量数据，指示测量位置的定位以改善预期结果，指示仪器的位置，或帮助用户正确地放置或控制仪器。它还可以通过提供运动信息来改善分析物监测，运动信息可用于帮助确定和减少或消除可能存在于监测信号内的运动相关信号伪影或噪声。

7. 发明申请

US20110054278A1 EMITTER DRIVER FOR NONINVASIVE PATIENT MONITOR 有权
标题翻译：非感染患者监护仪的发射器驱动器
公开(公告)号：US20110054278A1
公开(公告)日：2011-03-03
申请号：US12875062
申请日：2010-09-02
申请人： Johannes Bruinsma , Cristiano Dalvi , Marcelo Lamego
发明人： Johannes Bruinsma , Cristiano Dalvi , Marcelo Lamego
IPC分类号： A61B5/1455
CPC分类号： A61B5/14552 , A61B5/0059 , A61B5/6826 , A61B2560/045 , A61B2562/0233 , A61B2562/046 , A61B2562/222
摘要： Embodiments of the present disclosure include an emitter driver configured to be capable of addressing substantially 2N nodes with N cable conductors configured to carry activation instructions from a processor. In an embodiment, an address controller outputs an activation instruction to a latch decoder configured to supply switch controls to activate particular LEDs of a light source.
摘要翻译：本公开的实施例包括发射器驱动器，其被配置为能够寻址基本2N个节点，其中N个电缆导体被配置为携带来自处理器的激活指令。在一个实施例中，地址控制器向配置成提供开关控制以激活光源的特定LED的锁存解码器输出激活指令。

8. 发明申请

US20100026995A1 MULTI-STREAM SENSOR FOR NONINVASIVE MEASUREMENT OF BLOOD CONSTITUENTS 有权
标题翻译：用于无血压测量血液成分的多流量传感器
公开(公告)号：US20100026995A1
公开(公告)日：2010-02-04
申请号：US12534823
申请日：2009-08-03
申请人： Sean Merritt , Marcelo Lamego , Cristiano Dalvi , Hung Vo , Johannes Bruinsma , Jeroen Poeze , Ferdyan Lesmana , Massi Joe E. Kiani
发明人： Sean Merritt , Marcelo Lamego , Cristiano Dalvi , Hung Vo , Johannes Bruinsma , Jeroen Poeze , Ferdyan Lesmana , Massi Joe E. Kiani
IPC分类号： G01J1/42
CPC分类号： A61B5/1455 , A61B5/14532 , A61B5/14546 , A61B5/14552 , A61B5/6816 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/6843 , A61B2562/0233 , A61B2562/04 , A61B2562/046 , A61B2562/146
摘要： The present disclosure relates to a sensor having a set of photodetectors that are arranged at various locations to enable the measurement of blood glucose. The photodetectors are arranged across multiple locations. For example, the detector may comprise multiple photodetector arrays that are arranged to have a sufficient difference in mean path length to allow for noise cancellation and noise reduction. Walls may be used in the detector to separate individual photodetectors and prevent mixing of detected optical radiation between the different locations on the measurement site. A window may also be employed to facilitate the passing of optical radiation at various wavelengths for measuring glucose in the tissue.
摘要翻译：本公开涉及具有一组光电检测器的传感器，其被布置在各种位置以能够测量血糖。光电探测器布置在多个位置。例如，检测器可以包括多个光电检测器阵列，其布置成在平均路径长度上具有足够的差异以允许噪声消除和降噪。可以在检测器中使用壁来分离各个光电检测器，并防止检测的光辐射在测量位置上的不同位置之间的混合。还可以使用窗口来促进用于测量组织中葡萄糖的各种波长的光辐射的通过。

9. 发明申请

US20100004519A1 NOISE SHIELDING FOR A NONINVASIVE DEVICE 有权
标题翻译：非易失性设备的噪声屏蔽
公开(公告)号：US20100004519A1
公开(公告)日：2010-01-07
申请号：US12497528
申请日：2009-07-02
申请人： Marcelo Lamego , Sean Merritt , Cristiano Dalvi , Hung Vo , Johannes Bruinsma , Jeroen Poeze , Ferdyan Lesmana , Greg Olsen , Massi Joe E. Kiani
发明人： Marcelo Lamego , Sean Merritt , Cristiano Dalvi , Hung Vo , Johannes Bruinsma , Jeroen Poeze , Ferdyan Lesmana , Greg Olsen , Massi Joe E. Kiani
IPC分类号： A61B5/1455 , H01L31/0232 , H05K9/00
CPC分类号： A61B5/02427 , A61B5/02416 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/14551 , A61B5/14552 , A61B5/4875 , A61B5/6816 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/6843 , A61B5/70 , A61B5/7275 , A61B2562/146
摘要： A noninvasive physiological sensor for measuring one or more physiological parameters of a medical patient can include a bump interposed between a light source and a photodetector. The bump can be placed in contact with body tissue of a patient and thereby reduce a thickness of the body tissue. As a result, an optical pathlength between the light source and the photodetector can be reduced. In addition, the sensor can include a heat sink that can direct heat away from the light source. Moreover, the sensor can include shielding in the optical path between the light source and the photodetector. The shielding can reduce noise received by the photodetector.
摘要翻译：用于测量医疗患者的一个或多个生理参数的无创生理传感器可以包括插入在光源和光电检测器之间的凸块。凸起可以放置成与患者的身体组织接触，从而减少身体组织的厚度。结果，可以减少光源和光电检测器之间的光程。此外，传感器可以包括可将热量远离光源引导的散热器。此外，传感器可以包括在光源和光电检测器之间的光路中的屏蔽。屏蔽可以降低由光电检测器接收的噪声。

10. 发明申请

US20100004518A1 HEAT SINK FOR NONINVASIVE MEDICAL SENSOR 审中-公开
标题翻译：非接触式医疗传感器的散热器
公开(公告)号：US20100004518A1
公开(公告)日：2010-01-07
申请号：US12497506
申请日：2009-07-02
申请人： Hung Vo , Marcelo Lamego , Sean Merritt , Cristiano Dalvi , Johannes Bruinsma , Jeroen Poeze , Ferdyan Lesmana , Greg Olsen , Massi Joe E. Kiani
发明人： Hung Vo , Marcelo Lamego , Sean Merritt , Cristiano Dalvi , Johannes Bruinsma , Jeroen Poeze , Ferdyan Lesmana , Greg Olsen , Massi Joe E. Kiani
IPC分类号： A61B5/1468 , F28F7/00
CPC分类号： A61B5/02427 , A61B5/02416 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/14551 , A61B5/14552 , A61B5/4875 , A61B5/6816 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/6843 , A61B5/70 , A61B5/7275 , A61B2562/146
摘要： A noninvasive physiological sensor for measuring one or more physiological parameters of a medical patient can include a bump interposed between a light source and a photodetector. The bump can be placed in contact with body tissue of a patient and thereby reduce a thickness of the body tissue. As a result, an optical pathlength between the light source and the photodetector can be reduced. In addition, the sensor can include a heat sink that can direct heat away from the light source. Moreover, the sensor can include shielding in the optical path between the light source and the photodetector. The shielding can reduce noise received by the photodetector.
摘要翻译：用于测量医疗患者的一个或多个生理参数的无创生理传感器可以包括插入在光源和光电检测器之间的凸块。凸起可以放置成与患者的身体组织接触，从而减少身体组织的厚度。结果，可以减少光源和光电检测器之间的光程。此外，传感器可以包括可将热量远离光源引导的散热器。此外，传感器可以包括在光源和光电检测器之间的光路中的屏蔽。屏蔽可以降低由光电检测器接收的噪声。

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