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1. 发明授权

US08915385B2 Shock-absorbing coupler head for a coupling arrangement 有权
标题翻译：用于耦合装置的减震耦合器头
公开(公告)号：US08915385B2
公开(公告)日：2014-12-23
申请号：US13805537
申请日：2011-06-08
申请人： Johan Hansson , Mattias Hjort , Fredrik Hiswåls , Daniel Larsson , Anders Svedbo , Anders Westman
发明人： Johan Hansson , Mattias Hjort , Fredrik Hiswåls , Daniel Larsson , Anders Svedbo , Anders Westman
IPC分类号： B61G7/14 , B61G3/16 , B61G11/16
CPC分类号： B61G7/14 , B61G3/16 , B61G11/16
摘要： A coupler head for a coupling arrangement is shown, which coupler head includes a coupler head housing (6) extending in a longitudinal direction from a first end (6a), attachable to a drawbar, to a second end (6b), which is arranged to carry a coupling interface between coupled rail vehicles, which coupler head housing houses mechanical coupling components (8,9) effective for automatic coupling to the corresponding components of a connecting coupling arrangement. The coupler head is characterized in that the coupler head housing has at least one notch (11, 11′) for a predetermined and primarily axial compression thereof with absorption of energy from a deforming compressive force that is applied to the coupler head in the longitudinal direction thereof. The coupler head has preferably at least one notch (11, 11′) for a predetermined folding of the coupler head housing.
摘要翻译：示出了用于联接装置的联接器头，该联接器头部包括从可连接到牵引杆的第一端（6a）沿纵向方向延伸到第二端（6b）的联接头壳体（6），该第二端部布置以在耦合的轨道车辆之间承载耦合接口，所述耦合器头壳体容纳有效地自动耦合到连接耦合装置的相应部件的机械耦合部件（8,9）。耦合器头的特征在于，耦合器头壳体具有至少一个用于预定和主要轴向压缩的凹口（11,11'），其具有沿着纵向方向施加到耦合器头部的变形压缩力的能量吸收其中。联接头优选地具有至少一个用于联接器头壳体的预定折叠的凹口（11,11'）。

2. 发明申请

US20110124613A1 Novel Combination of Compounds to be Used in the Treatment of Airway Diseases, Especially Chronic Obstructive Pulmonary Disease (COPD) and Asthma 审中-公开
标题翻译：用于治疗气道疾病，特别是慢性阻塞性肺疾病（COPD）和哮喘的化合物的新型组合
公开(公告)号：US20110124613A1
公开(公告)日：2011-05-26
申请号：US12527754
申请日：2008-02-21
申请人： Tomas Eriksson , Johan Hansson , Marguerite Mensonides-Harsema , John Mo
发明人： Tomas Eriksson , Johan Hansson , Marguerite Mensonides-Harsema , John Mo
IPC分类号： A61K31/438 , C07D491/10 , C07D471/10 , A61K31/56 , A61P11/00 , A61P11/06
CPC分类号： A61K31/438 , A61K31/569 , C07D471/10 , C07D491/10
摘要： The present invention provides a pharmaceutical product comprising, in combination of, (a) a (therapeutically effective) dose of a first active ingredient, which is a compound of formula (I) or a pharmaceutically acceptable salt thereof; and (b) a (therapeutically effective) dose of a second active ingredient, which is a glucocorticoid receptor agonist; and optionally, (c) a (therapeutically effective) dose of a third active ingredient, which is a β2-agonist. The invention further relates to pharmaceutical compositions comprising said combination and to methods of treating treatment of airway diseases, especially chronic obstructive pulmonary disease (COPD) and asthma in mammals by administrating said combination. The invention further relates to a kit comprising the combination and use of said kit in treatment of airway diseases such as COPD and asthma.
摘要翻译：本发明提供了包含（a）（治疗有效）剂量的第一活性成分（其为式（I）化合物或其药学上可接受的盐）的药物产品，和（b）（治疗有效的）剂量的第二活性成分，其是糖皮质激素受体激动剂; 和（c）（治疗有效的）剂量的第三种活性成分，其是一种2-激动剂。本发明还涉及包含所述组合的药物组合物和通过施用所述组合来治疗气道疾病，特别是慢性阻塞性肺疾病（COPD）和哺乳动物哮喘的治疗方法。本发明还涉及包含所述试剂盒在治疗气道疾病如COPD和哮喘中的组合和用途的试剂盒。

3. 发明申请

US20090261819A1 SENSOR ARRANGEMENT 有权
标题翻译：传感器布置
公开(公告)号：US20090261819A1
公开(公告)日：2009-10-22
申请号：US12420893
申请日：2009-04-09
申请人： Johan Hansson , Ulf Nyberg
发明人： Johan Hansson , Ulf Nyberg
IPC分类号： G01B7/14
CPC分类号： G01D5/14
摘要： A sensor arrangement is arranged to detect at least one position of a displaceable component in a fluid device, which fluid device comprises a wall enclosing a cavity, in which cavity the component is displaced by pressurized fluid selectively applied to the component. The sensor arrangement includes a magnetic sensor mounted outside the wall and a first sensor element that is connected to the magnetic sensor and extends through the wall and a predetermined distance into the cavity. The magnetic sensor is arranged to detect the position of at least one predetermined second sensor element located on the displaceable component by sensing a change in magnetic flux induced in the first sensor element by the second sensor element.
摘要翻译：传感器布置被布置成检测流体装置中的可移动部件的至少一个位置，该流体装置包括封闭空腔的壁，在该空腔中该部件被选择性地施加到部件上的加压流体移位。传感器装置包括安装在壁外的磁传感器和连接到磁传感器并延伸穿过壁并且预定距离进入空腔的第一传感器元件。磁传感器被布置成通过感测第二传感器元件在第一传感器元件中感应的磁通量的变化来检测位于可位移部件上的至少一个预定的第二传感器元件的位置。

4. 发明申请

US20130105431A1 SHOCK-ABSORBING COUPLER HEAD FOR A COUPLING ARRANGEMENT 有权
标题翻译：用于联轴器安装的防震联轴器头
公开(公告)号：US20130105431A1
公开(公告)日：2013-05-02
申请号：US13805537
申请日：2011-06-08
申请人： Johan Hansson , Mattias Hjort , Fredrik Hiswåls , Daniel Larsson , Anders Svedbo , Anders Westman
发明人： Johan Hansson , Mattias Hjort , Fredrik Hiswåls , Daniel Larsson , Anders Svedbo , Anders Westman
IPC分类号： B61G7/14 , B61G3/16
CPC分类号： B61G7/14 , B61G3/16 , B61G11/16
摘要： A coupler head for a coupling arrangement is shown, which coupler head includes a coupler head housing (6) extending in a longitudinal direction from a first end (6a), attachable to a drawbar, to a second end (6b), which is arranged to carry a coupling interface between coupled rail vehicles, which coupler head housing houses mechanical coupling components (8,9) effective for automatic coupling to the corresponding components of a connecting coupling arrangement. The coupler head is characterized in that the coupler head housing has at least one notch (11, 11′) for a predetermined and primarily axial compression thereof with absorption of energy from a deforming compressive force that is applied to the coupler head in the longitudinal direction thereof. The coupler head has preferably at least one notch (11, 11′) for a predetermined folding of the coupler head housing.
摘要翻译：示出了用于联接装置的联接器头，该联接器头部包括从可连接到牵引杆的第一端（6a）沿纵向方向延伸到第二端（6b）的联接头壳体（6），该第二端部布置以在耦合的轨道车辆之间承载耦合接口，所述耦合器头壳体容纳有效地自动耦合到连接耦合装置的相应部件的机械耦合部件（8,9）。耦合器头的特征在于，耦合器头壳体具有至少一个用于预定和主要轴向压缩的凹口（11,11'），其具有沿着纵向方向施加到耦合器头部的变形压缩力的能量吸收其中。联接头优选地具有至少一个用于联接器头壳体的预定折叠的凹口（11,11'）。

5. 发明申请

US20060104204A1 Power efficient mobile terminal reception mode 审中-公开
标题翻译：高效移动终端接收模式
公开(公告)号：US20060104204A1
公开(公告)日：2006-05-18
申请号：US10987766
申请日：2004-11-12
申请人： Johan Hansson , Goran Pehrsson , Emma Wittenmark , Bjorn Rikte
发明人： Johan Hansson , Goran Pehrsson , Emma Wittenmark , Bjorn Rikte
IPC分类号： H04L12/26 , H04B7/212
CPC分类号： H04L1/0065 , H04L1/0045 , H04L1/0059 , H04L1/0061 , H04L1/0071
摘要： A message that comprises encoded bits interleaved over N transmission bursts, wherein N is greater than 1, is received by receiving fewer than N of the transmission bursts, whereby there exist remaining ones of the N transmission bursts that have not been received. All of the received transmission bursts are decoded to generate decoded data. It is then determined whether the decoded data is error free. Reception of remaining transmission bursts of the message is inhibited if the decoded data is error free, otherwise one or more remaining ones of the N transmission bursts are received.
摘要翻译：通过接收少于N个传输脉冲串来接收包括经N个传输脉冲串交错的编码比特，其中N大于1的消息，由此存在尚未被接收的N个传输脉冲串中的剩余的传输脉冲串。所有接收到的传输脉冲串被解码以产生解码的数据。然后确定解码的数据是否是无错误的。如果解码的数据是无错误的，则消息的剩余传输突发的接收被禁止，否则接收到N个传输突发中的一个或多个。

6. 发明授权

US5836950A Guide instrument 失效
标题翻译：导向仪器
公开(公告)号：US5836950A
公开(公告)日：1998-11-17
申请号：US836356
申请日：1997-05-13
申请人： Henrik Lars Johan Hansson
发明人： Henrik Lars Johan Hansson
IPC分类号： A61B17/16 , A61B17/00 , A61B17/17 , A61B17/58 , A61B17/76 , A61B17/88 , A61B17/90
CPC分类号： A61B17/1721 , A61B17/1735 , A61B17/8875 , A61B2017/0046
摘要： The present invention relates to a guide instrument which is adapted for use at operations for fixation of bone fragments at bone fractures, preferably femoral neck fractures, whereby the bone fragments are intended to be fixed relative to each other by means of at least two bone screws, whereby the guide instrument (1) is adapted for guiding a first and a second drill steel which are adapted for drilling passages in the bone fragments for the bone screws. The guide instrument (1) is designed to permit guiding of the drill steels, driving through of threaded front portions of the bone screws and guiding of uptapped or unthreaded rear portions of said bone screws.
摘要翻译： PCT No.PCT / SE95 / 01379 Sec。 371日期1997年5月13日 102（e）日期1997年5月13日PCT提交1995年11月21日PCT公布。公开号WO96 / 15727 日期：1996年5月30日本发明涉及一种导向仪器，其适用于在骨折固定的手术中使用，优选为股骨颈骨折，由此骨片段旨在相对于彼此固定在一起至少两个骨螺钉，由此导向仪器（1）适于引导适于在用于骨螺钉的骨碎片中钻孔通道的第一和第二钻钢。引导仪器（1）被设计成允许引导钻钢杆，通过骨螺钉的螺纹前部部分驱动并引导所述骨螺钉的上覆或无螺纹的后部。

7. 发明授权

US07788983B2 Sensor arrangement 有权
标题翻译：传感器布置
公开(公告)号：US07788983B2
公开(公告)日：2010-09-07
申请号：US12420893
申请日：2009-04-09
申请人： Johan Hansson , Ulf Nyberg
发明人： Johan Hansson , Ulf Nyberg
IPC分类号： G01F1/56
CPC分类号： G01D5/14
摘要： A sensor arrangement is arranged to detect at least one position of a displaceable component in a fluid device, which fluid device comprises a wall enclosing a cavity, in which cavity the component is displaced by pressurized fluid selectively applied to the component. The sensor arrangement includes a magnetic sensor mounted outside the wall and a first sensor element that is connected to the magnetic sensor and extends through the wall and a predetermined distance into the cavity. The magnetic sensor is arranged to detect the position of at least one predetermined second sensor element located on the displaceable component by sensing a change in magnetic flux induced in the first sensor element by the second sensor element.
摘要翻译：传感器布置被布置成检测流体装置中的可移动部件的至少一个位置，该流体装置包括封闭空腔的壁，在该空腔中该部件被选择性地施加到部件上的加压流体移位。传感器装置包括安装在壁外的磁传感器和连接到磁传感器并延伸穿过壁并且预定距离进入空腔的第一传感器元件。磁传感器被布置成通过感测第二传感器元件在第一传感器元件中感应的磁通量的变化来检测位于可位移部件上的至少一个预定的第二传感器元件的位置。

8. 发明申请

US20110136843A1 Novel Combination of Compounds to be Used in the Treatment of Airway Diseases, Especially Chronic Obstructive Pulmonary Disease (COPD) and Asthma 审中-公开
标题翻译：用于治疗气道疾病，特别是慢性阻塞性肺疾病（COPD）和哮喘的化合物的新型组合
公开(公告)号：US20110136843A1
公开(公告)日：2011-06-09
申请号：US12527760
申请日：2008-02-21
申请人： Tomas Eriksson , Johan Hansson , Marguerite Mensonides-Harsema , John Mo
发明人： Tomas Eriksson , Johan Hansson , Marguerite Mensonides-Harsema , John Mo
IPC分类号： A61K31/4468 , C07D211/58 , A61K31/438 , A61P11/00 , A61P11/06
CPC分类号： A61K31/438 , A61K31/4468 , A61K31/46
摘要： The present invention relates to a combination of (a) a chemokine receptor 1 (CCR1) antagonist and (b) a muscarinic antagonist. The invention further relates to pharmaceutical compositions comprising said combination and to methods of treatment of airway diseases, such as chronic obstructive pulmonary disease (COPD) and asthma in mammals by administrating said combination. The invention further relates to a kit comprising the combination and use of said kit in treatment of airway diseases.
摘要翻译：本发明涉及（a）趋化因子受体1（CCR1）拮抗剂和（b）毒蕈碱拮抗剂的组合。本发明还涉及包含所述组合的药物组合物和通过施用所述组合治疗气道疾病如慢性阻塞性肺病（COPD）和哺乳动物哮喘的方法。本发明还涉及包含所述试剂盒在治疗气道疾病中的组合和用途的试剂盒。

9. 发明申请

US20090215732A1 COMBINATION OF COMPOUNDS, WHICH CAN BE USED IN THE TREATMENT OF RESPIRATORY DISEASES, ESPECIALLY CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) AND ASTHMA 审中-公开
标题翻译：化合物的组合，可用于治疗呼吸道疾病，特别是慢性阻塞性肺疾病（COPD）和哮喘
公开(公告)号：US20090215732A1
公开(公告)日：2009-08-27
申请号：US12064864
申请日：2006-08-24
申请人： Tomas Eriksson , Johan Hansson
发明人： Tomas Eriksson , Johan Hansson
IPC分类号： A61K31/56 , A61P11/06
CPC分类号： A61K45/06 , A61K31/167 , A61K31/4375 , A61K31/4468 , A61K31/58 , A61K2300/00
摘要： The present invention provides pharmaceutical compositions comprising a glucocorticosteroid and a compound of formula: wherein m, R1, R2, R3, and R4 are as defined in the specification, and their use in therapy.
摘要翻译：本发明提供包含糖皮质激素和下式化合物的药物组合物：其中m，R 1，R 2，R 3和R 4如说明书中所定义，及其在治疗中的用途。

10. 发明授权

US07226595B2 Modified Chimeric superantigens and their use 有权
标题翻译：改性嵌合超级抗原及其用途
公开(公告)号：US07226595B2
公开(公告)日：2007-06-05
申请号：US10283838
申请日：2002-10-30
申请人： Per Antonsson , Per Bjork , Mikael Dohlsten , Terje Kalland , Lars Abrahmsen , Johan Hansson , Göran Forsberg
发明人： Per Antonsson , Per Bjork , Mikael Dohlsten , Terje Kalland , Lars Abrahmsen , Johan Hansson , Göran Forsberg
IPC分类号： A61K39/00
CPC分类号： C07K16/3023 , A61K38/00 , A61K47/68 , C07K14/31 , C07K16/3046 , C07K19/00 , C07K2317/732 , C07K2319/00
摘要： A conjugate between a target-seeking moiety and a modified superantigen, characterized in that the superantigen is a wild-type superantigen (SA I) in which an amino acid residue in a superantigen region (region I) determining binding to TCR, preferably TCRVβ, and T cell activation have been replaced by another amino acid residue while retaining the ability to activate a subset of T cells.In preferred embodiment the modified superantigen is a chimer between at least two wild-type superantigens (SA I, SA II etc) characterized in that one or more amino acid residues in a region determining binding to TCR and T cell activation have been interchanged between various wild-type superantigens.A therapeutic method making use of modified/chimeric superantigens as defined in the preceding paragraphs.An antibody preparation in which the cysteine residues that provide for interchain disulfide bonds have been mutated so as to forbid interchain disulfide bridges, preferably to serine residues, for use as pharmaceutical.
摘要翻译：目标寻找部分和修饰的超抗原之间的缀合物，其特征在于超抗原是野生型超抗原（SAI），其中超抗原区（区域I）中的氨基酸残基确定结合TCR，优选TCRVβ，并且T细胞激活已被另一个氨基酸残基替代，同时保留激活T细胞亚群的能力。在优选实施方案中，修饰的超抗原是至少两种野生型超级抗原（SA I，SA II等）之间的嵌合体，其特征在于确定结合TCR和T细胞活化的区域中的一个或多个氨基酸残基已经在各种野生型超抗原。使用前面段落中定义的修饰/嵌合超级抗原的治疗方法。其中提供链间二硫键的半胱氨酸残基已被突变以防止链间二硫键，优选丝氨酸残基用作药物的抗体制剂。

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