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1. 发明授权

US08258283B2 Method for detection of HCV at the real time PCR with intercalating dye 失效
标题翻译：用插入染料实时PCR检测HCV的方法
公开(公告)号：US08258283B2
公开(公告)日：2012-09-04
申请号：US12649239
申请日：2009-12-29
申请人： Dong Hwan Lee , Jin Seok Kang , Jae Sung Lee , Young Suk Park , Dong Hyun Kim
发明人： Dong Hwan Lee , Jin Seok Kang , Jae Sung Lee , Young Suk Park , Dong Hyun Kim
IPC分类号： C12Q1/68 , C07H21/04
CPC分类号： C12Q1/707 , C12Q1/6851
摘要： The present invention relates to a composition for detection of HCV by a single step reaction, comprising a specific primer and probe. In particular, the present invention relates to a composition for detection of HCV by a single step reaction, comprising the primer sequences of SEQ ID NOs:1 and 2; a composition for detection of HCV by a single step reaction, comprising both the primer sequences and a probe of SEQ ID NOs:5 or 9; a method for detecting HCV by a single step reaction, comprising the steps of obtaining a sample from a subject, and amplifying and detecting HCV using the primer and probe; and a kit comprising the primer and probe, in which the HCV detection method is characterized by a single step reaction.
摘要翻译：本发明涉及用于通过单步反应检测HCV的组合物，其包含特异性引物和探针。特别地，本发明涉及通过单步反应检测HCV的组合物，其包含SEQ ID NO：1和2的引物序列; 用于通过单步反应检测HCV的组合物，其包含引物序列和SEQ ID NO：5或9的探针; 一种通过单步反应检测HCV的方法，包括以下步骤：从受试者获得样品，并使用引物和探针扩增和检测HCV; 以及包含引物和探针的试剂盒，其中HCV检测方法的特征在于单步反应。

2. 发明申请

US20140127671A1 Simultaneous Diagnosis Kit For a Disease Due to a Respiratory Virus 审中-公开
标题翻译：用于呼吸道病毒疾病的同时诊断试剂盒
公开(公告)号：US20140127671A1
公开(公告)日：2014-05-08
申请号：US14000153
申请日：2012-02-20
申请人： Eun Joo Yoo , Young Suk Park , Ji Eun Heo , Jin Seok Kang
发明人： Eun Joo Yoo , Young Suk Park , Ji Eun Heo , Jin Seok Kang
IPC分类号： C12Q1/70
CPC分类号： C12Q1/701 , C12Q1/6883 , C12Q2600/158 , C12Q2600/16
摘要： The present invention relates to a kit for simultaneous diagnosis of viral respiratory diseases. To be more specific, the present invention is directed to a method for diagnosing viral respiratory diseases by detecting the genes specific to the respiratory disease-causing virus, a primer set for diagnosing the viral respiratory diseases used in the diagnosis method, a composition for simultaneous diagnosis of viral respiratory diseases, comprising the primer set, and a kit for simultaneous diagnosis of viral respiratory diseases, comprising the composition. When the primer set of the present invention for diagnosing the viral respiratory diseases is used, 14 different types of respiratory viruses can be simultaneously detected only with one reaction through real-time multiplex reverse transcription (RT)-PCR, and the onset of respiratory diseases caused by these viruses can be diagnosed. Thus, the primer set of the present invention can be widely used for prompt diagnosis and treatment of respiratory diseases.
摘要翻译：本发明涉及用于同时诊断病毒性呼吸道疾病的试剂盒。更具体地，本发明涉及一种通过检测对呼吸道性疾病病毒特异性的基因来诊断病毒性呼吸系统疾病的方法，用于诊断诊断方法中使用的病毒性呼吸系统疾病的引物组，用于同时包括引物组的病毒性呼吸系统疾病的诊断和用于同时诊断病毒性呼吸道疾病的试剂盒，其包含该组合物。当使用用于诊断病毒性呼吸系统疾病的本发明的引物组时，可以通过实时多重逆转录（RT）-PCR的一种反应和呼吸道疾病的发作，同时检测14种不同类型的呼吸道病毒可以诊断这些病毒引起的。因此，本发明的引物组可广泛用于呼吸系统疾病的迅速诊断和治疗。

3. 发明授权

US06491904B1 Topical composition containing human epidermal growth factor 有权
标题翻译：含有人表皮生长因子的局部组合物
公开(公告)号：US06491904B1
公开(公告)日：2002-12-10
申请号：US09623559
申请日：2000-09-06
申请人： Seung Yeob Lee , Jin Seok Kang , Jeom Soon Shim , Seung Wook Lim , Seung Hee Han , Byoung Kwang Lee , Young Hyo Yu , Jong Keun Chung
发明人： Seung Yeob Lee , Jin Seok Kang , Jeom Soon Shim , Seung Wook Lim , Seung Hee Han , Byoung Kwang Lee , Young Hyo Yu , Jong Keun Chung
IPC分类号： A61K3174
CPC分类号： A61K38/1808
摘要： The present invention relates to a topical composition containing human epidermal growth factor (hEGF) and polyoxyethylene-polyoxypropylene copolymer having a viscosity of 4-10 cps at 37° C, 60 rpm as the base for topical formulation to improve the wound healing ability of hEGF.
摘要翻译：本发明涉及含有人表皮生长因子（hEGF）和聚氧乙烯 - 聚氧丙烯共聚物的局部组合物，其在37℃，60rpm下的粘度为4-10cps，作为局部制剂的基础，以改善hEGF的伤口愈合能力。

4. 发明申请

US20100173284A1 Method for Detection of HCV at the Real Time PCR with Intercalating Dye 失效
标题翻译：用插入染料实时PCR检测HCV的方法
公开(公告)号：US20100173284A1
公开(公告)日：2010-07-08
申请号：US12649239
申请日：2009-12-29
申请人： Dong Hwan LEE , Jin Seok Kang , Jae Sung Lee , Young Suk Park , Dong Hyun Kim
发明人： Dong Hwan LEE , Jin Seok Kang , Jae Sung Lee , Young Suk Park , Dong Hyun Kim
IPC分类号： C12Q1/70
CPC分类号： C12Q1/707 , C12Q1/6851
摘要： The present invention relates to a composition for detection of HCV by a single step reaction, comprising a specific primer and probe. In particular, the present invention relates to a composition for detection of HCV by a single step reaction, comprising the primer sequences of SEQ ID NOs:1 and 2; a composition for detection of HCV by a single step reaction, comprising both the primer sequences and a probe of SEQ ID NOs:5 or 9; a method for detecting HCV by a single step reaction, comprising the steps of obtaining a sample from a subject, and amplifying and detecting HCV using the primer and probe; and a kit comprising the primer and probe, in which the HCV detection method is characterized by a single step reaction.
摘要翻译：本发明涉及用于通过单步反应检测HCV的组合物，其包含特异性引物和探针。特别地，本发明涉及通过单步反应检测HCV的组合物，其包含SEQ ID NO：1和2的引物序列; 用于通过单步反应检测HCV的组合物，其包含引物序列和SEQ ID NO：5或9的探针; 一种通过单步反应检测HCV的方法，包括以下步骤：从受试者获得样品，并使用引物和探针扩增和检测HCV; 以及包含引物和探针的试剂盒，其中HCV检测方法的特征在于单步反应。

5. 发明授权

US10106860B2 Simultaneous diagnosis kit for a disease due to a respiratory virus 有权
公开(公告)号：US10106860B2
公开(公告)日：2018-10-23
申请号：US14000153
申请日：2012-02-20
申请人： Eun Joo Yoo , Young Suk Park , Ji Eun Heo , Jin Seok Kang
发明人： Eun Joo Yoo , Young Suk Park , Ji Eun Heo , Jin Seok Kang
IPC分类号： C12Q1/68 , C12Q1/70 , C12Q1/6883
摘要： The present invention relates to a kit for simultaneous diagnosis of viral respiratory diseases. To be more specific, the present invention is directed to a method for diagnosing viral respiratory diseases by detecting the genes specific to the respiratory disease-causing virus, a primer set for diagnosing the viral respiratory diseases used in the diagnosis method, a composition for simultaneous diagnosis of viral respiratory diseases, comprising the primer set, and a kit for simultaneous diagnosis of viral respiratory diseases, comprising the composition. When the primer set of the present invention for diagnosing the viral respiratory diseases is used, 14 different types of respiratory viruses can be simultaneously detected only with one reaction through real-time multiplex reverse transcription (RT)-PCR, and the onset of respiratory diseases caused by these viruses can be diagnosed. Thus, the primer set of the present invention can be widely used for prompt diagnosis and treatment of respiratory diseases.

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