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1. 发明授权

US08882785B2 Endoscopic suturing device 有权
标题翻译：内镜缝合装置
公开(公告)号：US08882785B2
公开(公告)日：2014-11-11
申请号：US13121213
申请日：2008-09-29
申请人： Paul C. DiCesare , Jeffrey P. Radziunas
发明人： Paul C. DiCesare , Jeffrey P. Radziunas
IPC分类号： A61B17/04
CPC分类号： A61B17/0469
摘要： An endoscopic suturing device that can be employed to suture tissue using endoscopic techniques to place one or more stitches in tissue during a single intubation of an endoscope. The suturing device may include a suturing capsule with a suction chamber that is configured to capture tissue that is to be sutured. A needle is movable along a pathway across the suction chamber to penetrate and place stitches in the captured tissue. A catch is located distal to the suction chamber to receive and retain the suture during a stitching sequence. The catch may be movable along the needle pathway and configured to release the suture when the catch moves a predetermined distance along the pathway. The catch may be configured so that a predetermined amount of force is required to move the catch the predetermined distance required to release the suture.
摘要翻译：一种内窥镜缝合装置，其可用于使用内窥镜技术缝合组织，以在内窥镜的单次插管期间将一个或多个针迹放置在组织中。缝合装置可以包括具有吸引腔的缝合胶囊，其构造成捕获要被缝合的组织。针可以沿着穿过抽吸室的路径移动以穿过并将缝合放置在所捕获的组织中。捕获器位于吸入室的远侧以在缝合序列期间接收和保持缝合线。捕获器可以沿着针通道移动并且构造成当捕捉器沿着路径移动预定距离时释放缝合线。卡扣可以被构造成使得需要预定量的力来将卡扣移动以释放缝合线所需的预定距离。

2. 发明申请

US20100100074A1 IMPLANTABLE CATHETHER AND METHOD OF USING SAME 有权
标题翻译：可植入的导管及其使用方法
公开(公告)号：US20100100074A1
公开(公告)日：2010-04-22
申请号：US12643562
申请日：2009-12-21
申请人： A. DAVID SMITH , Dominick L. Mastri , Jeffrey P. Radziunas , Paul DiCesare , James Steven Kenny
发明人： A. DAVID SMITH , Dominick L. Mastri , Jeffrey P. Radziunas , Paul DiCesare , James Steven Kenny
IPC分类号： A61M25/16 , A61B17/3209
CPC分类号： A61M25/0097 , A61M25/0009 , A61M25/0014 , A61M39/06 , A61M39/0606 , A61M39/10 , A61M2027/004 , A61M2039/062 , A61M2039/1027
摘要： A catheter for implantation into a patient having a catheter tube having a distal end, a means for trimming the distal end of the catheter tube after subcutaneous insertion of the tip of the catheter lumen into a desired position within the patient to form a trimmed end portion, and a means for selectively positioning each respective lumen of the trimmed end portion of the catheter tube into fluid communication with the respective first end of one attachment tube. The attachment tube is select fluid communication with a desired medical device.
摘要翻译：一种用于植入具有具有远端的导管的患者的导管，用于在将导管内腔的尖端皮下插入患者体内的期望位置之后修整导管管的远端的装置，以形成修剪的端部以及用于选择性地定位导管管的修剪端部的每个相应内腔与一个附接管的相应第一端流体连通的装置。附件管是与期望的医疗装置的选择性流体连通。

3. 发明申请

US20100069930A1 Method and apparatus for minimally invasive delivery, tensioned deployment and fixation of secondary material prosthetic devices in patient body tissue, including hernia repair within the patient's herniation site 审中-公开
标题翻译：用于微创输送的方法和装置，张力部署和固定患者身体组织中的二次材料假体装置，包括患者疝位点内的疝修补
公开(公告)号：US20100069930A1
公开(公告)日：2010-03-18
申请号：US12586021
申请日：2009-09-16
申请人： Mitchell Roslin , Paresh C. Shah , Oleg Shikhman , Danial P. Ferreira , Jeffrey P. Radziunas , Christopher A. Battles
发明人： Mitchell Roslin , Paresh C. Shah , Oleg Shikhman , Danial P. Ferreira , Jeffrey P. Radziunas , Christopher A. Battles
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B2017/00659 , A61B2017/00663 , A61B2017/047 , A61F2/0063 , A61F2002/0072
摘要： Apparatus and methods enable insertion and tensioned deployment of a secondary material prosthetic device into a body cavity or other tissue of a patient, such as for example hernia repair mesh into the abdominopelvic cavity of a patient through the hernia site. The present invention establishes fixation sites for the prosthetic device and tensions it against the body tissue. It may also be used implant fixation devices within the body tissue so that the prosthetic device is tensioned into firm abutting contact with the body tissue. Instrument deployment and fixation struts may be advanced in retrograde fashion in order to reduce needed deployment volume within the patient's body cavity. The prosthetic device advantageously may be flexibly coupled to the instrument via fixation devices such as sutures, so as to increase orientation flexibility.
摘要翻译：装置和方法使得辅助材料假体装置能够插入和张紧部署到患者的体腔或其他组织中，例如疝修补通过疝部位进入患者的腹部腹腔。本发明建立了假体装置的固定位置并将其张紧到身体组织上。还可以在体内组织中使用植入物固定装置，使得假体装置被张紧成与身体组织紧密接触。仪器部署和固定支柱可以以逆行方式进行，以减少患者体腔内所需的展开体积。有利地，假体装置可以经由诸如缝合线的固定装置柔性地联接到器械，以便增加取向灵活性。

4. 发明授权

US07740616B2 Implantable catheter and method of using same 有权
标题翻译：可植入导管及其使用方法
公开(公告)号：US07740616B2
公开(公告)日：2010-06-22
申请号：US11392257
申请日：2006-03-29
申请人： A. David Smith , Dominick L. Mastri , Jeffrey P. Radziunas , Paul DiCesare , James Steven Kenny
发明人： A. David Smith , Dominick L. Mastri , Jeffrey P. Radziunas , Paul DiCesare , James Steven Kenny
IPC分类号： A61M25/02
CPC分类号： A61M25/0097 , A61M25/0009 , A61M25/0014 , A61M39/06 , A61M39/0606 , A61M39/10 , A61M2027/004 , A61M2039/062 , A61M2039/1027
摘要： A catheter for implantation into a patient having a catheter tube having a distal end, a means for trimming the distal end of the catheter tube after subcutaneous insertion of the tip of the catheter lumen into a desired position within the patient to form a trimmed end portion, and a means for selectively positioning each respective lumen of the trimmed end portion of the catheter tube into fluid communication with the respective first end of one attachment tube. The attachment tube is select fluid communication with a desired medical device.
摘要翻译：一种用于植入具有具有远端的导管的患者的导管，用于在将导管内腔的尖端皮下插入患者体内的期望位置之后修整导管管的远端的装置，以形成修剪的端部以及用于选择性地定位导管管的修剪端部的每个相应内腔与一个附接管的相应第一端流体连通的装置。附件管是与期望的医疗装置的选择性流体连通。

5. 发明授权

US06479298B1 Device and method for separating components of a fluid sample 有权
标题翻译：用于分离流体样品组分的装置和方法
公开(公告)号：US06479298B1
公开(公告)日：2002-11-12
申请号：US09454988
申请日：1999-12-03
申请人： Henry F. Miller , Fu-Chung Lin , Robert J. Losada , Jeffrey P. Radziunas , Jeffrey Karg
发明人： Henry F. Miller , Fu-Chung Lin , Robert J. Losada , Jeffrey P. Radziunas , Jeffrey Karg
IPC分类号： G01N118
CPC分类号： B01L3/50215 , G01N33/491 , Y10T436/25 , Y10T436/25375
摘要： A device and method for separating heavier and lighter fractions of a fluid sample. The device includes a plurality of constituents comprising a container and a composite element in the container. The composite element is a separator comprising at least two components and more particularly, a bellows with a seal body, a low-density float and a high-density ballast. A fluid sample is delivered to the container and the device is subjected to centrifugation whereby the centrifugal load causes the seal body of the separator to deform so that the separator migrates through the fluid sample and then stabilizes between the heavier and lighter fractions of the fluid sample. The seal body of the separator will resiliently return to its initial configuration upon termination of the centrifugal load such that the seal body sealingly engages the container and the composite element separates the heavier and lighter fractions of the fluid sample.
摘要翻译：用于分离流体样品的较重和较轻馏分的装置和方法。该装置包括多个构件，其包括容器中的容器和复合元件。复合元件是包括至少两个部件的分离器，更具体地，具有密封体，低密度浮子和高密度压载物的波纹管。将流体样品输送到容器并且使装置进行离心，由此离心负荷使得分离器的密封体变形，使得分离器通过流体样品移动，然后在流体样品的较重和较轻部分之间稳定。当离心负载终止时，分离器的密封体将弹性地返回到其初始构型，使得密封体密封地接合容器，并且复合元件分离流体样品的较重和较轻的部分。

6. 发明授权

US09078697B2 Surgical portal apparatus including movable housing 有权
标题翻译：手术入口设备包括可移动外壳
公开(公告)号：US09078697B2
公开(公告)日：2015-07-14
申请号：US12717280
申请日：2010-03-04
申请人： Michael E. Abrams , Jeffrey P. Radziunas
发明人： Michael E. Abrams , Jeffrey P. Radziunas
IPC分类号： A61B17/02 , A61B17/34
CPC分类号： A61B17/3462 , A61B17/02 , A61B17/3421 , A61B17/3423 , A61B2017/3425
摘要： A surgical portal apparatus includes a housing and a cannula member. The housing includes a seal mount and a flexible housing wall. The cannula member is connected to the housing and defines a longitudinal axis and passageway. The seal mount has an internal seal. The flexible housing wall is dimensioned to permit both axial and radial movement of the seal mount with respect to the longitudinal axis between a first position of the seal mount and a plurality of second positions of the seal mount. The seal mount may be biased by a biasing member toward the first position. In an embodiment, the biasing member is a spring that is engageable with the cannula member and the seal mount.
摘要翻译：手术入口装置包括壳体和套管构件。壳体包括密封安装件和柔性外壳壁。套管构件连接到壳体并且限定纵向轴线和通道。密封安装具有内部密封。该柔性外壳壁的尺寸被设计成允许密封安装件相对于纵向轴线在密封件安装件的第一位置和密封件安装件的多个第二位置之间的轴向和径向移动。密封安装件可以被偏置构件偏向第一位置。在一个实施例中，偏置构件是可与插管构件和密封件安装件接合的弹簧。

7. 发明授权

US08075573B2 Single intubation, multi-stitch endoscopic suturing system 有权
标题翻译：单插管，多针内窥镜缝合系统
公开(公告)号：US08075573B2
公开(公告)日：2011-12-13
申请号：US10847190
申请日：2004-05-17
申请人： Richard A. Gambale , Peter J. Lukin , Paul C. DiCesare , Christopher A. Battles , Jeffrey P. Radziunas , Danial P. Ferreira
发明人： Richard A. Gambale , Peter J. Lukin , Paul C. DiCesare , Christopher A. Battles , Jeffrey P. Radziunas , Danial P. Ferreira
IPC分类号： A61B17/04 , A61B17/12
CPC分类号： A61B17/0469 , A61B17/0467 , A61B17/0487 , A61B2017/00827 , A61B2017/045 , A61B2017/0464 , A61B2017/047
摘要： Provided is an endoscopic suturing system for joining internal body tissues in a variety of procedures. The system comprises a suturing capsule releasably mountable to the distal end of an endoscope and capable of forming multiple stitches in tissue at a plurality of locations without requiring withdrawal of the capsule from the patient between stitches. Also enclosed is a suture lock to secure the placed stitch that is delivered by a device introduced through the working channel of the indwelling endoscope. Suitable control handles for the suturing capsule and for the suture lock delivery device positioned at the proximal end of the endoscope are provided to facilitate operation by the user.
摘要翻译：提供了一种用于以各种方法连接内部身体组织的内窥镜缝合系统。该系统包括可释放地安装到内窥镜的远端的缝合胶囊，并且能够在多个位置处在组织中形成多个线圈，而不需要在线圈之间从患者中取出胶囊。还包括缝合线锁，用于固定由通过留置内窥镜的工作通道引入的装置输送的放置针迹。提供用于缝合胶囊和位于内窥镜的近端处的缝线锁输送装置的合适的控制手柄，以便于使用者的操作。

8. 发明申请

US20100240958A1 SURGICAL PORTAL APPARATUS INCLUDING MOVABLE HOUSING 有权
标题翻译：外科手术包括可移动房屋
公开(公告)号：US20100240958A1
公开(公告)日：2010-09-23
申请号：US12717280
申请日：2010-03-04
申请人： Michael E. Abrams , Jeffrey P. Radziunas
发明人： Michael E. Abrams , Jeffrey P. Radziunas
IPC分类号： A61B1/32
CPC分类号： A61B17/3462 , A61B17/02 , A61B17/3421 , A61B17/3423 , A61B2017/3425
摘要： A surgical portal apparatus includes a housing and a cannula member. The housing includes a seal mount and a flexible housing wall. The cannula member is connected to the housing and defines a longitudinal axis and passageway. The seal mount has an internal seal. The flexible housing wall is dimensioned to permit both axial and radial movement of the seal mount with respect to the longitudinal axis between a first position of the seal mount and a plurality of second positions of the seal mount. The seal mount may be biased by a biasing member toward the first position. In an embodiment, the biasing member is a spring that is engageable with the cannula member and the seal mount.
摘要翻译：手术入口装置包括壳体和套管构件。壳体包括密封安装件和柔性外壳壁。套管构件连接到壳体并且限定纵向轴线和通道。密封安装具有内部密封。该柔性外壳壁的尺寸被设计成允许密封安装件相对于纵向轴线在密封件安装件的第一位置和密封件安装件的多个第二位置之间的轴向和径向移动。密封安装件可以被偏置构件偏向第一位置。在一个实施例中，偏置构件是可与插管构件和密封件安装件接合的弹簧。

9. 发明授权

US06516953B1 Device for separating components of a fluid sample 有权
标题翻译：用于分离流体样品的组分的装置
公开(公告)号：US06516953B1
公开(公告)日：2003-02-11
申请号：US09452981
申请日：1999-12-02
申请人： Paul C. DiCesare , Jeffrey Karg , Fu-Chung Lin , Jeffrey P. Radziunas
发明人： Paul C. DiCesare , Jeffrey Karg , Fu-Chung Lin , Jeffrey P. Radziunas
IPC分类号： B01D2126
CPC分类号： G01N33/491 , A61B5/15003 , A61B5/150221 , A61B5/150236 , A61B5/150251 , A61B5/150351 , A61B5/150572 , A61B5/150755 , A61B5/154 , B01D21/0003 , B01D21/26 , B01D21/262 , B01D2221/10 , B01L3/50215 , B01L2300/042
摘要： A device and method is provided for separating components of a fluid sample. The device includes a plurality of constituents comprising a container, a liner in the container, a closure for the container and a composite element. The composite element is a seal plug with a density between the densities of the components of the fluid sample is releasably engaged with the container closure and with the liner. A needle cannula is used to deposit a fluid sample in the liner and the entire device is placed in a centrifuge. The centrifugal load causes the seal plug to separate from the closure and causes the liner to expand outwardly against the container. The seal plug migrates into the fluid sample and stabilizes between the densities of the components of the fluid sample. The liner will resiliently return to its initial configuration upon termination of centrifugal load such that the liner sealingly engages the seal plug and separates the components of the fluid sample.
摘要翻译：提供了用于分离流体样品的组分的装置和方法。该装置包括多个构件，其包括容器，容器中的衬垫，用于容器的封闭件和复合元件。复合元件是密封塞，其密度在流体样品的部件的密度之间与容器封闭件和衬套可释放地接合。使用针插管将流体样品沉积在衬垫中，并将整个装置放置在离心机中。离心载荷使得密封塞与封闭件分离并使衬套朝向容器向外扩张。密封塞移动到流体样品中并且在流体样品的组分的密度之间稳定。当离心负载终止时，衬套将弹性地返回到其初始构型，使得衬套密封地接合密封塞并分离流体样品的部件。

10. 发明授权

US08425555B2 Suture lock fastening device 有权
标题翻译：缝合锁紧固装置
公开(公告)号：US08425555B2
公开(公告)日：2013-04-23
申请号：US13330023
申请日：2011-12-19
申请人： Edward C. Page , Patrick Gutelius , Danial P. Ferreira , Jeffrey P. Radziunas
发明人： Edward C. Page , Patrick Gutelius , Danial P. Ferreira , Jeffrey P. Radziunas
IPC分类号： A61B17/04
CPC分类号： A61B17/0487 , A61B17/0467 , A61B17/0485 , A61B2017/045 , A61B2017/0488
摘要： A suture lock fastening device to cinch a suture in a suture lock, cut the suture end, and deploy the suture lock in response to a single movement of a user. The fastening device includes a fastening head with a retainer that is configured to hold a suture lock in the fastening head. To release the suture lock from the fastening head, the retainer is irreversibly deformed. The fastening device may include an axially movable cutter with a cutting edge to sever the ends of the suture close to the suture lock. A threading device may be preloaded into the fastening device to facilitate threading the suture through the fastening device.
摘要翻译：一种缝合线锁紧装置，用于将缝合线缝合在缝合线锁中，切割缝合线端部，并且响应于使用者的单次运动而部署缝合线锁。紧固装置包括具有保持器的紧固头部，该保持器构造成将缝合线锁定在紧固头部中。为了从紧固头释放缝合锁，保持器不可逆地变形。紧固装置可以包括具有切割刃的可轴向移动的切割器，以将缝合线的端部切割成靠近缝合线锁定。穿线装置可以被预加载到紧固装置中以便于缝合线穿过紧固装置。

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