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1. 发明授权

US10960334B2 Magnetic closure system for HVAC filter grilles and method of use 有权
公开(公告)号：US10960334B2
公开(公告)日：2021-03-30
申请号：US16171694
申请日：2018-10-26
申请人： Jeffrey Corbett , Jeffrey Stewart
发明人： Jeffrey Corbett , Jeffrey Stewart
IPC分类号： B01D46/00 , B01D46/10 , F24F13/08
摘要： A magnetic closure system for HVAC filter grilles has at least one magnet coupled to the HVAC filter grille, the at least one magnet positioned so as to be interposed between the HVAC filter grille and an inner frame for receiving the HVAC filter grille, the magnet abutting both the filter grille and inner frame so as to magnetically couple the HVAC filter grille to the inner frame; and at least one handle on the exterior surface of the filter grille.

2. 发明申请

US20190126183A1 MAGNETIC CLOSURE SYSTEM FOR HVAC FILTER GRILLES AND METHOD OF USE 审中-公开
公开(公告)号：US20190126183A1
公开(公告)日：2019-05-02
申请号：US16171694
申请日：2018-10-26
申请人： Jeffrey Corbett , Jeffrey Stewart
发明人： Jeffrey Corbett , Jeffrey Stewart
IPC分类号： B01D46/00 , B01D46/10 , F24F13/08
摘要： A magnetic closure system for HVAC filter grilles has at least one magnet coupled to the HVAC filter grille, the at least one magnet positioned so as to be interposed between the HVAC filter grille and an inner frame for receiving the HVAC filter grille, the magnet abutting both the filter grille and inner frame so as to magnetically couple the HVAC filter grille to the inner frame; and at least one handle on the exterior surface of the filter grille.

3. 发明授权

US07952046B2 Resistance welding gun with independent actuators 有权
标题翻译：电阻焊枪独立执行器
公开(公告)号：US07952046B2
公开(公告)日：2011-05-31
申请号：US11743744
申请日：2007-05-03
申请人： Michael J. Beneteau , D. Jeffrey Corbett , Mark J. Dolata
发明人： Michael J. Beneteau , D. Jeffrey Corbett , Mark J. Dolata
IPC分类号： B23K11/10 , B23K9/32
CPC分类号： B23K11/314 , Y10T74/16
摘要： An actuator assembly for a welding gun is provided that has at least three positions in the example. The actuator assembly includes separate working and retract actuators. The working actuator includes a working rod movable between first and second positions. The retract actuator includes a retract rod independently movable relative to the working rod between third and fourth positions. The retract actuator is external to and non-concentrically arranged relative to the working actuator in the example shown. Actuation of the working and retract actuators is coordinated to provide at least three positions while enabling the actuators to be changed or modified independently from one another. A latching device is configured to selectively interlock the working and retract actuators to one another automatically in response to movement the working rod from the first position to the second position.
摘要翻译：提供了一种用于焊枪的致动器组件，其在该示例中具有至少三个位置。致动器组件包括单独的工作和回缩致动器。工作致动器包括可在第一和第二位置之间移动的工作杆。缩回致动器包括可在第三和第四位置之间相对于工作杆独立移动的缩回杆。在所示示例中，缩回致动器相对于工作致动器在外部并且非同心地布置。协调工作和后退致动器的致动以提供至少三个位置，同时使致动器能够彼此独立地改变或修改。锁定装置构造成响应于将工作杆从第一位置移动到第二位置而自动地将工作和后退的致动器互相联动。

4. 发明申请

US20060217398A1 SUBSTITUTED PYRIMIDINE DERIVATIVES 审中-公开
标题翻译：取代的吡咯烷衍生物
公开(公告)号：US20060217398A1
公开(公告)日：2006-09-28
申请号：US11424073
申请日：2006-06-14
申请人： Jeffrey Corbett , Micheal Ennis , Kristine Frank , Jian-Min Fu , Robert Hoffman , Patrick Verhoest
发明人： Jeffrey Corbett , Micheal Ennis , Kristine Frank , Jian-Min Fu , Robert Hoffman , Patrick Verhoest
IPC分类号： A61K31/506 , A61K31/4439
CPC分类号： C07D239/42 , C07D213/72
摘要： This invention relates to compounds of Formula I, a stereoisomer thereof, a pharmaceutically acceptable salt thereof, a prodrug thereof, or a pharmaceutically acceptable salt of a prodrug thereof. The compounds interact with CRF1 receptors, including human CRF1 receptors. This invention also relates to methods of using the compounds of the invention to treat a disorder or condition, the treatment of which can be effected or facilitated by antagonizing a CRF receptor, such as CNS disorders or diseases, particularly anxiety-related disorders such as anxiety, and mood disorders such as major depression.
摘要翻译：本发明涉及式I化合物，其立体异构体，其药学上可接受的盐，其前药或其前药的药学上可接受的盐。这些化合物与CRF1受体（包括人CRF 1受体）相互作用。本发明还涉及使用本发明化合物治疗病症或病症的方法，所述疾病或病症的治疗可以通过拮抗CRF受体如CNS疾病或疾病，特别是焦虑相关疾病例如焦虑来实现或促进，以及心理障碍如重度抑郁症。

5. 发明申请

US20050250816A1 Positive allosteric modulators of the nicotinic acetylcholine receptor 审中-公开
标题翻译：烟碱型乙酰胆碱受体的正变构调节剂
公开(公告)号：US20050250816A1
公开(公告)日：2005-11-10
申请号：US11174239
申请日：2005-07-01
申请人： David Piotrowski , Bruce Rogers , William McWhorter , Daniel Walker , Jeffrey Corbett , Vincent Groppi , Daniel Rudmann
发明人： David Piotrowski , Bruce Rogers , William McWhorter , Daniel Walker , Jeffrey Corbett , Vincent Groppi , Daniel Rudmann
IPC分类号： C07C275/34 , C07C275/40 , C07C323/44 , C07C335/18 , C07D213/75 , C07D231/16 , C07D231/40 , C07D233/88 , C07D261/14 , C07D277/48 , C07D277/56 , C07D277/82 , C07D285/12 , C07D285/135 , C07D413/12 , C07D417/12 , C07D285/08 , C07D261/04 , C07D277/04
CPC分类号： C07D213/75 , C07C275/34 , C07C275/40 , C07C323/44 , C07C335/18 , C07D231/16 , C07D231/40 , C07D233/88 , C07D261/14 , C07D277/48 , C07D277/56 , C07D277/82 , C07D285/135 , C07D413/12 , C07D417/12
摘要： The invention provides compounds of Formula I: These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals used to treat diseases or conditions in which α7 nAChR is known to be involved.
摘要翻译：本发明提供式I化合物：这些化合物可以是药物盐或组合物的形式，可以是纯对映体形式或外消旋混合物，并且可用于用于治疗已知α7nAChR的疾病或病症的药物涉及。

6. 发明申请

US20050101613A1 Substituted pyrimidine derivatives 失效
标题翻译：取代的嘧啶衍生物
公开(公告)号：US20050101613A1
公开(公告)日：2005-05-12
申请号：US10839055
申请日：2004-05-05
申请人： Jeffrey Corbett , Michael Ennis , Kristine Frank , Jian-Min Fu , Robert Hoffman , Patrick Verhoest
发明人： Jeffrey Corbett , Michael Ennis , Kristine Frank , Jian-Min Fu , Robert Hoffman , Patrick Verhoest
IPC分类号： C07D213/72 , C07D239/42 , A61K31/506 , A61K31/4439 , C07D43/02
CPC分类号： C07D239/42 , C07D213/72
摘要： This invention relates to compounds of Formula I, a stereoisomer thereof, a pharmaceutically acceptable salt thereof, a prodrug thereof, or a pharmaceutically acceptable salt of a prodrug thereof. The compounds interact with CRF, receptors, including human CRF, receptors. This invention also relates to methods of using the compounds of the invention to treat a disorder or condition, the treatment of which can be effected or facilitated by antagonizing a CRF receptor, such as CNS disorders or diseases, particularly anxiety-related disorders such as anxiety, and mood disorders such as major depression.
摘要翻译：本发明涉及式I化合物，其立体异构体，其药学上可接受的盐，其前药或其前药的药学上可接受的盐。该化合物与CRF，受体（包括人类CRF）受体相互作用。本发明还涉及使用本发明化合物治疗病症或病症的方法，所述疾病或病症的治疗可以通过拮抗CRF受体如CNS疾病或疾病，特别是焦虑相关疾病例如焦虑来实现或促进，以及心理障碍如重度抑郁症。

7. 发明申请

US20080271565A1 RESISTANCE WELDING GUN WITH INDEPENDENT ACTUATORS 有权
标题翻译：具有独立执行器的电阻焊枪
公开(公告)号：US20080271565A1
公开(公告)日：2008-11-06
申请号：US11743744
申请日：2007-05-03
申请人： Michael J. Beneteau , D. Jeffrey Corbett , Mark J. Dolata
发明人： Michael J. Beneteau , D. Jeffrey Corbett , Mark J. Dolata
IPC分类号： F16H35/08
CPC分类号： B23K11/314 , Y10T74/16
摘要： An actuator assembly for a welding gun is provided that has at least three positions in the example. The actuator assembly includes separate working and retract actuators. The working actuator includes a working rod movable between first and second positions. The retract actuator includes a retract rod independently movable relative to the working rod between third and fourth positions. The retract actuator is external to and non-concentrically arranged relative to the working actuator in the example shown. Actuation of the working and retract actuators is coordinated to provide at least three positions while enabling the actuators to be changed or modified independently from one another. A latching device is configured to selectively interlock the working and retract actuators to one another automatically in response to movement the working rod from the first position to the second position.
摘要翻译：提供了一种用于焊枪的致动器组件，其在该示例中具有至少三个位置。致动器组件包括单独的工作和回缩致动器。工作致动器包括可在第一和第二位置之间移动的工作杆。缩回致动器包括可在第三和第四位置之间相对于工作杆独立移动的缩回杆。在所示示例中，缩回致动器相对于工作致动器在外部并且非同心地布置。协调工作和后退致动器的致动以提供至少三个位置，同时使致动器能够彼此独立地改变或修改。锁定装置构造成响应于将工作杆从第一位置移动到第二位置而自动地将工作和后退的致动器互相联动。

8. 发明申请

US20050143403A1 Substituted pyrimidinones and pyrimidinthiones 审中-公开
标题翻译：取代的嘧啶酮和嘧啶硫酮
公开(公告)号：US20050143403A1
公开(公告)日：2005-06-30
申请号：US10827750
申请日：2004-04-20
申请人： Jian-Min Fu , Michael Ennis , Robert Hoffman , Patrick Verhoest , John Mickelson , Jeffrey Corbett
发明人： Jian-Min Fu , Michael Ennis , Robert Hoffman , Patrick Verhoest , John Mickelson , Jeffrey Corbett
IPC分类号： A61K31/513 , A61P25/00 , C07D401/14 , C07D403/04 , G01N33/76 , C07D43/04
CPC分类号： G01N33/76 , C07D401/14 , C07D403/04 , G01N2333/726
摘要： This invention relates to substituted pyrimidinone and pyrimidithione derivatives that bind with high affifnity to CRF1 receptors, including human CRF1 receptors. This invention also relates to methods of using the compounds of the invention to treat a disorder or condition, the treatment of which can be effected or facilitated by antagonizing a CRF receptor, such as CNS disorders or diseases, particularly anxiety disorders, and depression and stress related disorders.
摘要翻译：本发明涉及与CRF 1受体（包括人CRF 1受体）具有高亲和性结合的取代的嘧啶酮和嘧啶硫酮衍生物。本发明还涉及使用本发明化合物治疗病症或病症的方法，其治疗可以通过拮抗CRF受体如CNS疾病或疾病，特别是焦虑症，抑郁和应激来实现或促进相关疾病。

9. 发明申请

US20050038040A1 Compounds as CRF1 receptor antagonists 失效
标题翻译：化合物作为CRF1受体拮抗剂
公开(公告)号：US20050038040A1
公开(公告)日：2005-02-17
申请号：US10840485
申请日：2004-05-06
申请人： Jeffrey Corbett , Michael Ennis , Kristine Frank , Jian-Min Fu , Robert Hoffman , Patrick Verhoest
发明人： Jeffrey Corbett , Michael Ennis , Kristine Frank , Jian-Min Fu , Robert Hoffman , Patrick Verhoest
IPC分类号： A61P25/00 , C07D401/14 , C07D403/14 , C07D417/14 , A61K31/497 , C07D43/14
CPC分类号： C07D401/14 , C07D403/14 , C07D417/14
摘要： The present invention relates to compounds of Formula I, or a stereoisomer thereof, a pharmaceutically acceptable salt thereof, or a prodrug thereof. The compounds of the inventions are CRF1 receptor antagonists. Compounds of the invention are useful for treating, in a warm-blooded animal, particularly a mammal, and more particularly a human, various disorders that are associated with CRF or CRF1 receptors, or disorders the treatment of which can be effected or facilitated by antagonizing CRF1 receptors.
摘要翻译：本发明涉及式I化合物或其立体异构体，其药学上可接受的盐或其前药。本发明的化合物是CRF1受体拮抗剂。本发明的化合物可用于在温血动物特别是哺乳动物中治疗，特别是治疗与CRF或CRF1受体相关的各种疾病，或其治疗可通过拮抗作用或促进 CRF1受体。

10. 发明申请

US20050049257A1 Substituted aryl 1, 4-pyrazine derivatives 失效
标题翻译：取代的芳基1,4-吡嗪衍生物
公开(公告)号：US20050049257A1
公开(公告)日：2005-03-03
申请号：US10844004
申请日：2004-05-12
申请人： Patrick Verhoest , Jeffrey Corbett , Michael Ennis , Kristine Frank , Jian-Min Fu , Robert Hoffman
发明人： Patrick Verhoest , Jeffrey Corbett , Michael Ennis , Kristine Frank , Jian-Min Fu , Robert Hoffman
IPC分类号： C07D241/18 , C07D241/20 , C07D241/26 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D409/12 , C07D491/04 , G01N33/74 , A61K31/4965 , C07D43/02
CPC分类号： C07D241/18 , C07D241/20 , C07D241/26 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D409/12 , C07D491/04 , G01N33/74 , G01N2333/5751 , G01N2500/02 , Y10S206/828
摘要： Substituted aryl 1,4-pyrazine derivatives and their use in treating anxiety disorders, depression and stress related disorders are disclosed.
摘要翻译：公开了取代的芳基1,4-吡嗪衍生物及其在治疗焦虑症，抑郁症和应激相关疾病中的用途。

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