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1. 发明授权

US08344031B2 Compositions for the treatment of signs of aging 有权
标题翻译：用于治疗衰老迹象的组合物
公开(公告)号：US08344031B2
公开(公告)日：2013-01-01
申请号：US12534214
申请日：2009-08-03
申请人： Eduardo Ruvolo , Michael D. Southall , Binoy K. Bordoloi , Elvin R. Lukenbach , Gloria Jean Lukenbach, legal representative
发明人： Eduardo Ruvolo , Michael D. Southall , Binoy K. Bordoloi , Elvin R. Lukenbach
IPC分类号： A61K8/41 , A61K31/133 , A61Q19/08
CPC分类号： A61Q19/06 , A61K8/41 , A61Q19/08
摘要： The present invention features a method of treating at least one sign of aging on the skin selected from the group consisting of enhancing the elasticity of said skin, enhancing the firmness of said skin, and reducing the appearance of wrinkles or cellulite on the skin, by administering to skin in need of such treatment a composition comprising at least one compound of the formula I or formula II: wherein R1, R2, R3, R4, and R5 independently, are selected from the group consisting of hydrogen, C1-C6 alkyl, C1-C6 hydroxyalkyl, or a cosmetically acceptable salt thereof.
摘要翻译：本发明的特征在于一种治疗至少一种皮肤老化迹象的方法，所述衰老迹象选自由增强皮肤弹性，增强皮肤紧致度，减少皮肤上皱纹或脂肪团出现的组成，向需要这种治疗的皮肤施用包含至少一种式I或式II化合物的组合物：其中R 1，R 2，R 3，R 4和R 5独立地选自氢，C 1 -C 6烷基， C1-C6羟基烷基或其化妆品可接受的盐。

2. 发明申请

US20080015554A1 Treatment of skin with light and a benefit agent to mitigate acne 审中-公开
标题翻译：用光和有益剂治疗皮肤以减轻痤疮
公开(公告)号：US20080015554A1
公开(公告)日：2008-01-17
申请号：US11572164
申请日：2005-07-15
申请人： Curtis Cole , Jean Lukenbach , Gregory Skover
发明人： Curtis Cole , Jean Lukenbach , Gregory Skover
IPC分类号： A61B18/18
CPC分类号： A61N5/062 , A61N5/0616
摘要： The present invention relates to treatment of the skin and, more particularly, to the application of light to the skin, followed by the optical application of a benefit agent to said skin.
摘要翻译：本发明涉及皮肤的治疗，更具体地说，涉及对皮肤的光的应用，随后将有益剂光学应用于所述皮肤。

3. 发明申请

US20060269580A1 Treatment of skin with light and a benefit agent to mitigate acne 审中-公开
标题翻译：用光和有益剂治疗皮肤以减轻痤疮
公开(公告)号：US20060269580A1
公开(公告)日：2006-11-30
申请号：US11183420
申请日：2005-07-15
申请人： Curtis Cole , Jean Lukenbach , Gregory Skover
发明人： Curtis Cole , Jean Lukenbach , Gregory Skover
IPC分类号： A61K8/64 , A61K8/02 , A61H21/00
CPC分类号： A61N5/062 , A61N5/0616
摘要： Methods of mitigating acne include exposing an expanse of skin to light; terminating the exposure of the skin to the light; and applying a benefit agent to the expanse of skin after a delay following the termination. The light exposure may be for a period of less than about one hour, and the light may be suitable for either (a) exciting porphyrins associated with the expanse of skin into an energetic state suitable for destroying acne-causing micro-organisms, or (b) for heating lipids present in sebaceous glands within the expanse of skin in order to modulate the flow of sebum in said sebaceous glands, or (c) for reducing inflammation. The benefit agent is suitable for either (a) providing anti-microbial action that is complementary to either said modulating of said sebum by said band of light, or complementary to said reduction of inflammation by said light or (b) providing sebum-modulating action that is complementary to either said destruction of said acne-causing microorganisms or complementary to said reduction of inflammation by said light; or (c) providing anti-inflammation that is complementary to either said modulating of said sebum by said band of light, or complementary to said destruction of said acne-causing microorganisms. These treatments may be repeated, as necessary.
摘要翻译：减轻痤疮的方法包括将一大片皮肤暴露于光; 终止皮肤暴露于光线; 并且在终止后延迟之后将有益剂施用于皮肤的膨胀。光照可能为小于约1小时的时间，并且光可以适用于（a）将与the皮相关的卟啉激发成适于破坏引起痤疮的微生物的能量状态，或（ b）用于加热存在于皮肤范围内的皮脂腺中的脂质，以调节所述皮脂腺中皮脂的流动，或（c）减少炎症。有益试剂适合于（a）提供抗微生物作用，所述抗微生物作用与由所述光束对所述皮脂的所述调节互补，或与所述光的所述炎症减轻互补或（b）提供皮脂调节作用其与所述痤疮引起的微生物的所述破坏或所述光的所述炎症减轻相互补充; 或（c）提供与由所述光带调节所述皮脂互补或与所述痤疮微生物的所述破坏互补的抗炎。必要时可以重复这些处理。

4. 发明申请

US20090292027A1 COMPOSITIONS FOR THE TREATMENT OF SIGNS OF AGING 有权
标题翻译：用于治疗老化症状的组合物
公开(公告)号：US20090292027A1
公开(公告)日：2009-11-26
申请号：US12534214
申请日：2009-08-03
申请人： Eduardo Ruvolo , Michael D. Southall , Binoy K. Bordoloi , Elvin R. Lukenbach , Gloria Jean Lukenbach
发明人： Eduardo Ruvolo , Michael D. Southall , Binoy K. Bordoloi , Elvin R. Lukenbach , Gloria Jean Lukenbach
IPC分类号： A61K8/41 , A61K31/133 , A61Q19/08
CPC分类号： A61Q19/06 , A61K8/41 , A61Q19/08
摘要： The present invention features a method of treating at least one sign of aging on the skin selected from the group consisting of enhancing the elasticity of said skin, enhancing the firmness of said skin, and reducing the appearance of wrinkles or cellulite on the skin, by administering to skin in need of such treatment a composition comprising at least one compound of the formula I or formula II: wherein R1, R2, R3, R4, and R5 independently, are selected from the group consisting of hydrogen, C1-C6 alkyl, C1-C6 hydroxyalkyl, or a cosmetically acceptable salt thereof.
摘要翻译：本发明的特征在于一种治疗至少一种皮肤老化迹象的方法，所述衰老迹象选自由增强皮肤弹性，增强皮肤紧致度，减少皮肤上皱纹或脂肪团出现的组成，向需要这种治疗的皮肤施用包含至少一种式I或式II化合物的组合物：其中R 1，R 2，R 3，R 4和R 5独立地选自氢，C 1 -C 6烷基， C1-C6羟基烷基或其化妆品可接受的盐。

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