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1. 发明授权

US06794981B2 Integratable-fluid flow and property microsensor assembly 失效
标题翻译：可积分流体流量和性能微传感器组件
公开(公告)号：US06794981B2
公开(公告)日：2004-09-21
申请号：US10150851
申请日：2002-05-16
申请人： Aravind Padmanabhan , Jay G. Schwichtenberg , Cleopatra Cabuz , Ernest Satren
发明人： Aravind Padmanabhan , Jay G. Schwichtenberg , Cleopatra Cabuz , Ernest Satren
IPC分类号： H01C304
CPC分类号： G01F1/6842 , G01F1/6845 , G01F5/00 , G01N1/2247 , G01N25/18 , G01N25/488 , G01N33/0014 , G01N2001/2285
摘要： An integratable fluid flow and property microsensor assembly is configured to be operably embedded in a microfluidic cartridge of the type used in lab-on-a-chip systems. The assembly is a robust package having a microstructure flow sensor contained within a housing in order to achieve a robust sensing device. The cartridge provides a flow path to the assembly, which directs the fluid across the flow sensor and returns the fluid to the cartridge flow path. The flow sensor monitors the controlled flow of fluid and transmits signals indicative of that flow. The assembly structure provides a robust sensor that is operable and accurate in many different applications.
摘要翻译：可整合的流体流动和性质微传感器组件被配置为可操作地嵌入在芯片实验室系统中使用的类型的微流体盒中。该组件是具有包含在壳体内的微结构流量传感器的鲁棒封装，以便实现鲁棒的感测装置。墨盒提供到组件的流动路径，其引导流体穿过流量传感器并将流体返回到墨盒流动路径。流量传感器监测流体的受控流动并传输指示该流量的信号。组装结构提供了一个鲁棒的传感器，在许多不同的应用中可操作和准确。

2. 发明申请

US20080290114A1 Drug Delivery Flow Controller 审中-公开
标题翻译：药物输送流量控制器
公开(公告)号：US20080290114A1
公开(公告)日：2008-11-27
申请号：US11754138
申请日：2007-05-25
申请人： Eugen I. Cabuz , Jay G. Schwichtenberg
发明人： Eugen I. Cabuz , Jay G. Schwichtenberg
IPC分类号： B67D5/16
CPC分类号： A61M5/14244 , A61M5/16881 , A61M5/16886
摘要： A drug delivery system for delivering a fluid to a desired location within a body that uses two control loops to control fluid flow: a first control loop in which a pressure source moves the fluid at an approximate rate, and a second control loop where a variable impedance mechanism more precisely controls the flow rate. After the fluid has moved through the chambers of these two control loops, a flow sensor measures the flow rate, sends the flow rate information to the control electronics, which then adjusts the pressure and impedance in a closed-loop manner to maintain a constant, desired flow rate. The drug delivery device may be used in portable or wearable mechanisms.
摘要翻译：一种用于将流体输送到使用两个控制回路以控制流体流动的主体内的期望位置的药物输送系统：压力源以近似速率移动流体的第一控制回路和其中变量阻抗机制更精确地控制流量。在流体移动通过这两个控制回路的腔室之后，流量传感器测量流速，将流量信息发送到控制电子设备，控制电子装置然后以闭环方式调节压力和阻抗以保持恒定，所需流速。药物递送装置可以用于便携式或可穿戴机构。

3. 发明授权

US07277166B2 Cytometer analysis cartridge optical configuration 有权
标题翻译： Cytometer分析盒光学配置
公开(公告)号：US07277166B2
公开(公告)日：2007-10-02
申请号：US10908543
申请日：2005-05-16
申请人： Aravind Padmanabhan , Jay G. Schwichtenberg , Bernard S. Fritz , Cleopatra Cabuz , Ernest A. Satren
发明人： Aravind Padmanabhan , Jay G. Schwichtenberg , Bernard S. Fritz , Cleopatra Cabuz , Ernest A. Satren
IPC分类号： G01N21/01 , G01N33/48 , G01N1/10 , G01N15/02
CPC分类号： G01N15/1459 , B01L3/502715 , B01L9/527 , B01L2200/025 , B01L2200/027 , B01L2200/0636 , B01L2200/0689 , B01L2300/0645 , B01L2300/0654 , B01L2400/0487 , B01L2400/0633 , G01N15/1456 , G01N15/1484 , G01N2015/008 , G01N2015/1452 , G01N2015/1486
摘要： A medium having microfluidic circuitry for sampling and analyses. The medium may be a cartridge having a window countersunk into it and containing a flow channel. The flow channel may have items of interest flowing through it. Analyses of these items may be optical involving one or more light sources emanating light to and one or more light detectors receiving light from the channel. There are various configurations so that source and detector light cones may reach the flow channel without obscuration or interference of the light to and from the flow channel in the window.
摘要翻译：具有用于取样和分析的微流体电路的介质。该介质可以是具有一个窗口沉入其中并包含流动通道的盒。流动通道可以具有流过其的兴趣物品。这些项目的分析可以是光学的，涉及发射光的一个或多个光源和从该通道接收光的一个或多个光检测器。存在各种配置，使得源和检测器光锥可以到达流动通道而不会使光在窗口中的流动通道的光线不受干扰或干扰。

4. 发明授权

US07320338B2 Microvalve package assembly 有权
标题翻译：微型阀组件
公开(公告)号：US07320338B2
公开(公告)日：2008-01-22
申请号：US10908998
申请日：2005-06-03
申请人： Eugen I. Cabuz , Jay G. Schwichtenberg
发明人： Eugen I. Cabuz , Jay G. Schwichtenberg
IPC分类号： F16K11/20
CPC分类号： F15C5/00 , Y10T137/7668 , Y10T137/87885
摘要： A microvalve assembly that can help protect a microvalve or an assembly of microvalves from the environment. Such a microvalve assembly may be mechanically assembled, without the use of adhesives and/or other materials that might out-gas and/or otherwise reduce the performance of the electrostatically actuated devices contained therein. In particular, a microvalve assembly can include a base fixture, a clamp fixture that is configured to be attached to the base fixture, and an electrostatically actuated microvalve that is disposed between the base fixture and the clamp fixture. The clamp fixture may be mechanically secured to the base fixture.
摘要翻译：一个微型阀组件，可以帮助保护微型阀或将微型阀组件与环境保护起来。这样的微型阀组件可以机械地组装，而不使用粘合剂和/或其它可能气体和/或以其它方式降低其中所含静电致动装置的性能的其它材料。特别地，微型阀组件可以包括基座固定件，构造成附接到基座固定装置的夹具固定装置，以及设置在基座固定装置和夹具夹具之间的静电致动微型阀。夹具夹具可以机械地固定到基座固定件上。

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