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1. 发明申请

US20070254382A1 Method and biosensor for analysis 失效
标题翻译：方法和生物传感器进行分析
公开(公告)号：US20070254382A1
公开(公告)日：2007-11-01
申请号：US11785238
申请日：2007-04-16
申请人： Inger Vikholm , Janusz Sadowski
发明人： Inger Vikholm , Janusz Sadowski
IPC分类号： G01N33/536
CPC分类号： G01N33/54393 , G01N33/54373 , Y10S435/808 , Y10S435/962 , Y10S436/805 , Y10S436/806 , Y10S436/81
摘要： In a method for analysis biomolecules (3) attached to a solid surface of a substrate (1) are used for detecting the presence of analytes (4) in a sample by binding of the analytes to the biomolecules. The biomolecules (3) are attached directly to the surface of the substrate together with biomolecule-repellent molecules (5), which cover the surface between the biomolecules (3) to prevent nonspecific binding of analytes (4) and other biomolecules. The invention relates also to a biosensor where biomolecules (3) are attached directly to the substrate (1) together with biomolecule-repellent molecules (5), which cover the surface between the biomolecules (3) to prevent non-specific binding of analytes (4) and other biomolecules. The biomolecules (5) can be self-assembled hydrophilic polymers. One example of using the invention is immunological analysis using surface plasmon resonance (SPR).
摘要翻译：在分析方法中，连接到基质（1）的固体表面的生物分子（3）用于通过将分析物与生物分子结合来检测样品中分析物（4）的存在。生物分子（3）与生物分子驱避分子（5）直接连接到基底表面，分子（5）覆盖生物分子（3）之间的表面，以防止分析物（4）与其他生物分子的非特异性结合。本发明还涉及一种生物传感器，其中生物分子（3）与生物分子排斥分子（5）一起直接连接到基底（1），其覆盖生物分子（3）之间的表面，以防止分析物的非特异性结合（ 4）和其他生物分子。生物分子（5）可以是自组装的亲水性聚合物。使用本发明的一个实例是使用表面等离子体共振（SPR）的免疫学分析。

2. 发明申请

US20080024783A1 Method and Device for Carrying Out Surface Plasmon Resonance Measurement 失效
标题翻译：执行表面等离子体共振测量的方法和装置
公开(公告)号：US20080024783A1
公开(公告)日：2008-01-31
申请号：US10579774
申请日：2003-11-19
申请人： Janusz Sadowski
发明人： Janusz Sadowski
IPC分类号： G01N21/55 , G02B5/08
CPC分类号： G01N21/553
摘要： A method and a device for carrying out surface plasmon resonance measurement. A beam of electromagnetic radiation is produced by a source of electromagnetic radiation. The beam of electromagnetic radiation is directed through a prism onto a material layer in an angle of incidence, which material layer covers a planar surface of the prism. A resonance phenomenon is caused. A beam of reflected electromagnetic radiation is produced and directed by the surface to a detector for detecting the level of intensity of the beam of reflected electromagnetic radiation. The change of intensity of the beam of reflected electromagnetic radiation, caused by the surface resonance phenomenon, is measured. The beam of reflected electromagnetic radiation is reflected with a mirror to the detector.
摘要翻译：用于进行表面等离子共振测量的方法和装置。一束电磁辐射是由电磁辐射源产生的。电磁辐射束以入射角通过棱镜穿过材料层，该材料层覆盖棱镜的平面。引起共振现象。反射的电磁辐射束由表面产生并引导到检测器，用于检测反射电磁辐射束的强度水平。测量由表面共振现象引起的反射电磁辐射束的强度变化。反射的电磁辐射束被镜子反射到检测器。

3. 发明申请

US20070157873A1 Method of fabrication and device comprising elongated nanosize elements 审中-公开
标题翻译：制造方法和包括细长纳米尺寸元件的装置
公开(公告)号：US20070157873A1
公开(公告)日：2007-07-12
申请号：US10571520
申请日：2004-09-10
申请人： Jonas Hauptmann , Ane Jensen , Poul Erik Lindelof , Jesper Nygaard , Janusz Sadowski
发明人： Jonas Hauptmann , Ane Jensen , Poul Erik Lindelof , Jesper Nygaard , Janusz Sadowski
IPC分类号： C30B13/00 , C30B23/00 , C30B25/00 , C30B28/12
CPC分类号： B82Y20/00 , C30B25/02 , C30B25/18
摘要： A method of fabricating devices comprising elongated nanosize elements as well as such devices are disclosed. The devices comprise epitaxially grown layers into which elongated nanosize elements, such as carbon nanotubes, are incorporated. A substrate supporting epitaxial growth of an epitaxial layer is provided, elongated nanosize elements is provided onto the substrate and epitaxially overgrown with an epitaxial layer. The elongate nanosize elements are thereby at least partly encapsulated by the epitaxially grown layer. One or more components are prepared in the layer, the one or more components being prepared by means of lithography. Devices with carbon nanotubes as the active element may thereby be provided. The method is suitable for hybrid devices, hybrid between conventional semiconductor devices and nano-devices.
摘要翻译：公开了一种制造包括细长纳米尺寸元件的装置的方法以及这种装置。这些器件包括外延生长层，其中引入了纳米尺寸细长的元件，例如碳纳米管。提供了支持外延层的外延生长的衬底，将长的纳米尺寸元件提供到衬底上并外延地覆盖有外延层。因此，细长的纳米尺寸元件至少部分地被外延生长层包封。在该层中制备一种或多种组分，通过光刻制备一种或多种组分。因此可以提供具有碳纳米管作为有源元件的器件。该方法适用于混合器件，在常规半导体器件和纳米器件之间进行杂交。

4. 发明授权

US07009186B2 Method for monitoring of polymer in liquid state 失效
标题翻译：液态聚合物监测方法
公开(公告)号：US07009186B2
公开(公告)日：2006-03-07
申请号：US10250575
申请日：2002-01-03
申请人： Janusz Sadowski , Jyrki Salminen , Peter Huber , Camie Heffels , Marian Mours , Klaus Reindel , Jürgen Ettmüller
发明人： Janusz Sadowski , Jyrki Salminen , Peter Huber , Camie Heffels , Marian Mours , Klaus Reindel , Jürgen Ettmüller
IPC分类号： G01N21/88
CPC分类号： G01N21/33 , G01N21/21
摘要： In a method for monitoring of polymer in a liquid state, such as a polymer melt or resin, to detect inhomogeneities therein, such as the presence of other phase objects, especially gels in a matrix formed of the liquid state, the polymer in a liquid state flowing past an inspection point is monitored. At the inspection point, electromagnetic radiation in the form of UV light or polarised electromagnetic radiation is passed through the flow chamber (1) and received by a detector (8), and the absorption of the UV light or the changes in the state of polarisation of the electromagnetic radiation caused by the inhomogeneities are used to observe them.
摘要翻译：在用于监测液态聚合物（例如聚合物熔体或树脂）的方法中，为了检测其中的不均匀性，例如存在其它相物体，特别是由液态形成的基质中的凝胶，液体中的聚合物监测流经检查点的状态。在检查点，紫外线或极化电磁辐射形式的电磁辐射通过流动室（1）并被检测器（8）接收，并且紫外线的吸收或极化状态的变化的不均匀性引起的电磁辐射用于观察它们。

5. 发明授权

US07701582B2 Method and device for carrying out surface plasmon resonance measurement 失效
标题翻译：用于进行表面等离子体共振测量的方法和装置
公开(公告)号：US07701582B2
公开(公告)日：2010-04-20
申请号：US10579774
申请日：2003-11-19
申请人： Janusz Sadowski
发明人： Janusz Sadowski
IPC分类号： G01N21/55
CPC分类号： G01N21/553
摘要： A method and a device for carrying out surface plasmon resonance measurement. A beam of electromagnetic radiation is produced by a source of electromagnetic radiation. The beam of electromagnetic radiation is directed through a prism onto a material layer in an angle of incidence, which material layer covers a planar surface of the prism. A resonance phenomenon is caused. A beam of reflected electromagnetic radiation is produced and directed by the surface to a detector for detecting the level of intensity of the beam of reflected electromagnetic radiation. The change of intensity of the beam of reflected electromagnetic radiation, caused by the surface resonance phenomenon, is measured. The beam of reflected electromagnetic radiation is reflected with a mirror to the detector.
摘要翻译：用于进行表面等离子共振测量的方法和装置。一束电磁辐射是由电磁辐射源产生的。电磁辐射束以入射角通过棱镜穿过材料层，该材料层覆盖棱镜的平面。引起共振现象。反射的电磁辐射束由表面产生并引导到检测器，用于检测反射电磁辐射束的强度水平。测量由表面共振现象引起的反射电磁辐射束的强度变化。反射的电磁辐射束被镜子反射到检测器。

6. 发明授权

US07510882B2 Method and biosensor for analysis 失效
标题翻译：方法和生物传感器进行分析
公开(公告)号：US07510882B2
公开(公告)日：2009-03-31
申请号：US11785238
申请日：2007-04-16
申请人： Inger Vikholm , Janusz Sadowski
发明人： Inger Vikholm , Janusz Sadowski
IPC分类号： G01N33/543 , G01N33/551 , G01N33/552 , G01N33/553
CPC分类号： G01N33/54393 , G01N33/54373 , Y10S435/808 , Y10S435/962 , Y10S436/805 , Y10S436/806 , Y10S436/81
摘要： In a method for analysis biomolecules (3) attached to a solid surface of a substrate (1) are used for detecting the presence of analytes (4) in a sample by binding of the analytes to the biomolecules. The biomolecules (3) are attached directly to the surface of the substrate together with biomolecule-repellent molecules (5), which cover the surface between the biomolecules (3) to prevent nonspecific binding of analytes (4) and other biomolecules. The invention relates also to a biosensor where biomolecules (3) are attached directly to the substrate (1) together with biomolecule-repellent molecules (5), which cover the surface between the biomolecules (3) to prevent non-specific binding of analytes (4) and other biomolecules. The biomolecules (5) can be self-assembled hydrophilic polymers. One example of using the invention is immunological analysis using surface plasmon resonance (SPR).
摘要翻译：在分析方法中，连接到基质（1）的固体表面的生物分子（3）用于通过将分析物与生物分子结合来检测样品中分析物（4）的存在。生物分子（3）与生物分子驱避分子（5）直接连接到基底表面，分子（5）覆盖生物分子（3）之间的表面，以防止分析物（4）与其他生物分子的非特异性结合。本发明还涉及一种生物传感器，其中生物分子（3）与生物分子排斥分子（5）一起直接连接到基底（1），其覆盖生物分子（3）之间的表面，以防止分析物的非特异性结合（ 4）和其他生物分子。生物分子（5）可以是自组装的亲水性聚合物。使用本发明的一个实例是使用表面等离子体共振（SPR）的免疫学分析。

7. 发明授权

US07332327B2 Method and biosensor for analysis 有权
标题翻译：方法和生物传感器进行分析
公开(公告)号：US07332327B2
公开(公告)日：2008-02-19
申请号：US10164652
申请日：2002-06-10
申请人： Inger Vikholm , Janusz Sadowski
发明人： Inger Vikholm , Janusz Sadowski
IPC分类号： C12M1/34
CPC分类号： G01N33/54393 , G01N33/54373 , Y10S435/808 , Y10S435/962 , Y10S436/805 , Y10S436/806 , Y10S436/81
摘要： In a method for analysis biomolecules (3) attached to a solid surface of a substrate (1) are used for detecting the presence of analytes (4) in a sample by binding of the analytes to the biomolecules. The biomolecules (3) are attached directly to the surface of the substrate together with biomolecule-repellent molecules (5), which cover the surface between the biomolecules (3) to prevent nonspecific binding of analytes (4) and other biomolecules. The invention relates also to a biosensor where biomolecules (3) are attached directly to the substrate (1) together with biomolecule-repellent molecules (5), which cover the surface between the biomolecules (3) to prevent non-specific binding of analytes (4) and other biomolecules. The biomolecules (5) can be self-assembled hydrophilic polymers. One example of using the invention is immunological analysis using surface plasmon resonance (SPR).
摘要翻译：在分析方法中，连接到基质（1）的固体表面的生物分子（3）用于通过将分析物与生物分子结合来检测样品中分析物（4）的存在。生物分子（3）与生物分子驱避分子（5）直接连接到基底表面，分子（5）覆盖生物分子（3）之间的表面，以防止分析物（4）与其他生物分子的非特异性结合。本发明还涉及一种生物传感器，其中生物分子（3）与生物分子排斥分子（5）一起直接连接到基底（1），其覆盖生物分子（3）之间的表面，以防止分析物的非特异性结合（ 4）和其他生物分子。生物分子（5）可以是自组装的亲水性聚合物。使用本发明的一个实例是使用表面等离子体共振（SPR）的免疫学分析。

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