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1. 发明专利

PT2826476T FLUIDO DE DIÁLISE ISENTO DE CÁLCIO 未知
公开(公告)号：PT2826476T
公开(公告)日：2021-03-25
申请号：PT13176623
申请日：2013-07-16
申请人： JAN VAN DER MEULEN , M R KORTE B V , G M T DE JONG B V
IPC分类号： A61K31/194 , A61K31/7004 , A61K33/10 , A61K33/14 , A61M1/16 , A61P7/08

2. 发明授权

US06686341B1 Nutritional compositions which contain slightly negatively charged, non-digestible polysaccharides and use thereof for reducing transport through tight junctions 失效
标题翻译：含有微量带负电荷的不消化多糖的营养组合物及其用于减少紧密连接处的运输
公开(公告)号：US06686341B1
公开(公告)日：2004-02-03
申请号：US09937395
申请日：2002-01-02
申请人： Pieter Brandt Bijlsma , Jacques Alphons Groot , Johannes Wilhelmus Timmermans , Jan Van Der Meulen , Amanda Johanna Kiliaan
发明人： Pieter Brandt Bijlsma , Jacques Alphons Groot , Johannes Wilhelmus Timmermans , Jan Van Der Meulen , Amanda Johanna Kiliaan
IPC分类号： A61K31715
CPC分类号： A61K31/736 , A23C11/106 , A23K20/163 , A23K50/00 , A23K50/60 , A23L29/238 , A23L29/273 , A23L33/21 , A23L33/40 , A23V2002/00 , A61K31/715 , A61K31/721 , A23V2250/51 , A23V2250/606 , A23V2250/628 , A23V2250/612 , A23V2250/02 , A23V2250/61 , A23V2250/156 , A23V2250/708
摘要： A nutritional composition which contains slightly negatively charged non-digestible polysaccharides having a molecular weight of 8 kD to 40,000 kD, characterized in that the rise in the viscosity of the composition caused by the polysaccharides is less than 20 mpa·s. This nutritional composition is used to reduce the uptake of high molecular weight substances, allergens and microorganisms through the intestinal wall, more particularly to reduce transport of high molecular weight substances, allergens and microorganisms through the intestinal wall, ore particularly to reduce transport of high molecular weight substances, allergens and microorganisms through the tight junctions in the intestines. The nutritional compositions can be used to prevent or to treat allergies, allergic reactions, sepsis and inflammatory processes, such as those which can arise under emotional and physical stress, ischaemia, reperfusion damage during and after operations, following radiation treatment and/or chemotherapy of cancer patients and in the case of inflammatory intestinal diseases, diarrhoea and allergies.
摘要翻译：一种营养组合物，其含有分子量为8kD至40,000kD的微量带负电荷的不消化多糖，其特征在于由多糖引起的组合物粘度的升高小于20mpa.s. 这种营养组合物用于通过肠壁减少高分子量物质，过敏原和微生物的摄取，更特别是减少高分子量物质，过敏原和微生物通过肠壁，矿石的运输，特别是减少高分子量的运输重量物质，过敏原和微生物通过肠道紧密连接。营养组合物可用于预防或治疗过敏，过敏反应，败血症和炎症过程，例如在情绪和身体压力下可能出现的那些，局部缺血，手术期间和手术后的再灌注损伤，放射治疗和/或化疗后在癌症患者和炎性肠道疾病的情况下，腹泻和过敏。

3. 发明授权

US5245854A Press tool and an adaptor and a press therefor 失效
标题翻译：新闻工具和适配器及其新闻
公开(公告)号：US5245854A
公开(公告)日：1993-09-21
申请号：US817906
申请日：1992-01-08
申请人： Gerritt Bruggink , Jan van der Meulen
发明人： Gerritt Bruggink , Jan van der Meulen
IPC分类号： B21D5/02 , B30B1/00
CPC分类号： B21D5/0236 , B21D5/0209
摘要： The invention relates to a press tool with a receiving structure end for receiving into a receiving structure of a folding press, which end is connected via a central portion to a tool end, comprising at least one safety member which can protrude out of a side surface of the receiving structure end, to an adaptor therefor and to a press equipped therewith.

4. 发明授权

US06730661B1 Nutritional composition which contain non-digestible polysaccharides and use thereof to reduce transport through tight junctions 有权
标题翻译：含有不易消化的多糖的营养组合物及其用途，以减少通过紧密结合的运输
公开(公告)号：US06730661B1
公开(公告)日：2004-05-04
申请号：US10089371
申请日：2002-07-16
申请人： Amanda Johanne Kiliaan , Jacques Alphons Groot , Johannes Wilhelmus Timmermans , Jan Van Der Meulen , Katrien Maria Jozefa Van Laere , Pieter Brandt Bijlsma
发明人： Amanda Johanne Kiliaan , Jacques Alphons Groot , Johannes Wilhelmus Timmermans , Jan Van Der Meulen , Katrien Maria Jozefa Van Laere , Pieter Brandt Bijlsma
IPC分类号： A61K31715
CPC分类号： A23K20/163 , A23K50/00 , A23K50/60 , A23L29/238 , A23L29/244 , A23L29/273 , A23L33/21 , A23V2002/00 , A61K31/721 , A61K31/736 , A23V2250/5042 , A23V2250/50 , A23V2250/60 , A23V2250/156 , A23V2250/70
摘要： The present invention relates to the use of one or more non-digestible polysaccharides selected from the group consisting of dextrans having a molecular weight of 8 kD to 40,000 kD, hydrolysed (gluco)mannans having a molecular weight of 0.5 kD to 1,000 kD and hydrolysed (galacto) mannans having a molecular weigth of 0.5 kD to 1,000 kD for the preparation of a nutritional composition to reduce the uptake of high molecular weight substances, allergens and microorganisms through the intestinal wall, more particularly to reduce transport of high molecular weight substances, allergens and microorganisms through the tight junctions in the intestines, the rise in the viscosity of the nutritional composition caused by the polysaccharides being less than 20 mPa.s. The nutritional compositions can be used to prevent or to treat allergy, allergic reactions, sepsis and inflammatory processes, such as can arise under emotional and physical stress, ischaemia, reperfusion damage during and after operations, after radiation treatment and/or chemotherapy of cancer patients and in the case of inflammatory diseases of the intestine, diarrhoea and allergies.
摘要翻译：本发明涉及一种或多种选自分子量为8kD至40,000kD的葡聚糖，分子量为0.5kD至1,000kD的水解（葡萄糖）甘露聚糖的非消化性多糖的用途，并将其水解（galacto）甘露聚糖，其具有0.5kD至1,000kD的分子量，用于制备营养组合物，以减少通过肠壁吸收高分子量物质，变应原和微生物，更特别地，减少高分子量物质的运输，过敏原和微生物通过肠道紧密连接，由多糖引起的营养组合物的粘度上升小于20mPa.s。营养组合物可用于预防或治疗过敏，过敏反应，败血症和炎症过程，例如可能在情绪和身体压力下出现，局部缺血，手术期间和手术后的再灌注损伤，放射治疗和/或癌症患者化疗后并且在肠道炎性疾病的情况下，腹泻和过敏。

5. 发明授权

US5022256A Clamping device 失效
标题翻译：夹紧装置
公开(公告)号：US5022256A
公开(公告)日：1991-06-11
申请号：US414777
申请日：1989-09-29
申请人： Jan van der Meulen
发明人： Jan van der Meulen
IPC分类号： B21D37/14 , B21D5/02
CPC分类号： B21D5/0209 , B21D5/0236
摘要： The invention relates to a clamping device for the clamping of at least one piece of tooling, for instance an upper tooling or a press, which device comprises:two clamping jaws moveable towards and away from one another, between which the tooling can be clamped,pressure means, for instance at least one hydraulic cylinder for pressing the clamping jaws towards one another with force at energizing thereof, andat least one locking element present between the clamping jaws for co-action with an edge present on the tooling,such that the tooling in the absence of energizing of the pressure means can be pushed with at least one edge over the locking element, hook over the edge, and thus prevents the tool from falling,and is characterized in thata resilient strip, which is attached between the clamping jaws to one clamping jaw and which as a result of its own resilience lies in untensioned state at a distance from a pressure surface of this clamping jaw, whereby in the absence of energizing of the pressure means, the tooling can, through a sufficiently great tilting round a portion provided with a locking edge, be carried with its edge in and out of engagement with the locking edge and can pass over the locking edge, and to such a resilient strip.
摘要翻译：本发明涉及一种用于夹持至少一个工具（例如上部工具或压力机）的夹紧装置，该装置包括：两个夹钳可以彼此相对移动并远离彼此移动，在该夹爪之间可夹紧工具，压力装置，例如至少一个液压缸，用于在夹紧爪的作用下用力将夹钳向彼此挤压，以及存在于夹钳之间的至少一个锁定元件，用于与存在于工具上的边缘协同作用，使得在不存在压力装置通电的情况下，可以将至少一个边缘推压在锁定元件上方，钩在边缘上，从而防止工具掉落，并且其特征在于，弹性带附接在夹钳夹在一个夹紧爪上，由于其自身的弹性，其处于与该夹爪的压力表面相距一定距离处的未张紧状态，由此在没有激磁加压装置，工具可以通过足够大的倾斜使设置有锁定边缘的部分被承载，其边缘与锁定边缘接合并脱离与锁定边缘的接合，并且可以越过锁定边缘弹性条。

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