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1. 发明授权

US09216100B2 Medical device 有权
标题翻译：医疗装置
公开(公告)号：US09216100B2
公开(公告)日：2015-12-22
申请号：US13375261
申请日：2009-05-30
申请人： Jürgen Seibold , Erhard Müller , Karel Volenec , Petr Sittner , Ludek Heller , Jan Pilch
发明人： Jürgen Seibold , Erhard Müller , Karel Volenec , Petr Sittner , Ludek Heller , Jan Pilch
IPC分类号： A61F2/06 , A61F2/90 , A61F2/07 , A61L31/02 , A61L31/10 , A61L31/14 , D02G3/36 , D02G3/44 , D03D3/02 , D03D13/00 , D03D15/00 , D03D27/00
CPC分类号： A61F2/90 , A61F2/06 , A61F2/07 , A61F2002/075 , A61L31/022 , A61L31/10 , A61L31/14 , A61L2400/16 , C08L2201/12 , D02G3/36 , D02G3/448 , D03D3/02 , D03D13/004 , D03D13/008 , D03D15/0027 , D03D15/0077 , D03D27/00 , D10B2401/046 , D10B2509/06 , C08L67/02
摘要： A medical device includes yarns made of a shape memory material and polymer yarns, wherein the yarns made of said shape memory material include polymer sheathing.
摘要翻译：医疗装置包括由形状记忆材料和聚合物纱线制成的纱线，其中由所述形状记忆材料制成的纱线包括聚合物护套。

2. 发明申请

US20120018413A1 METHOD OF HEAT TREATMENT AND/OR INSPECTION OF FUNCTIONAL MECHANICAL PROPERTIES, PARTICULARLY TRANSFORMATION STRAIN AND/OR STRENGTH, OF SHAPE MEMORY ALLOY FILAMENTS AND APPARATUS FOR THE APPLICATION OF THIS METHOD 审中-公开
公开(公告)号：US20120018413A1
公开(公告)日：2012-01-26
申请号：US13262899
申请日：2010-05-04
申请人： Jan Pilch , Petr Sittner
发明人： Jan Pilch , Petr Sittner
IPC分类号： H05B1/00 , G01R27/08 , G01N25/00 , G01N29/11
CPC分类号： C22F1/10 , C22F1/006
摘要： A method of heat treatment and/or inspection of functional mechanical properties, particularly transformation strain and/or strength, of shape memory alloy filaments and apparatus for the application of this method.This invention introduces a method and equipment for nonconventional thermo-electro-mechanical treatment of continuous and discontinuous SMA filaments, particularly NiTi, allowing for setting their functional mechanical properties, particularly transformation strain and/or strength, as required by the user. Heat treatment of continuous SMA filaments is realized on an apparatus consisting of respooling system with driving units for feeding and taking spools and at least two electrical contacts allowing conductive for electrical contact of the respooled filament and electric current source. When applying the method, an effective filament temperature is first evaluated from the interpolated experimentally determined dependence of transformation strain and/or strength of the filament achieved by range of heat treatments characterized by various effective filament temperatures and tensile stress. Heat treatment is then performed by supplying the electric power calculated from this effective filament temperature to the segment of the treated SMA filament. Heat treatment can also be performed utilizing on-line control of the supplied electric current in a feedback to the on-line measured filament temperature and/or change of electric resistance before and after the treatment. Compared to currently used conventional heat treatment of SMA filaments in environmental furnace, the filament treated by the present method is exposed to much higher temperatures for much shorter time allowing for efficient, less energy consuming and compact heat treatment of continuous SMA filaments for applications in technical textile production. Functional mechanical properties different from those achievable by conventional heat treatment can be given to the treated SMA filaments. In addition, this invention introduces a method for inspection of the homogeneity of continuous SMA filaments consisting in measurement of the electrical resistance, temperature and/or characteristics of the ultrasonic signal passing through the filament during respooling. The homogeneity of the SMA filament is evaluated as the deviation of the actually measured value of one of these quantities from the expected value. The method is realized on apparatus with respooling system and sensors of the above introduced signals.

3. 发明申请

US20120116492A1 MEDICAL DEVICE 有权
标题翻译：医疗装置
公开(公告)号：US20120116492A1
公开(公告)日：2012-05-10
申请号：US13375261
申请日：2009-05-30
申请人： Jürgen Seibold , Erhard Müller , Karel Volenec , Petr Sittner , Ludek Heller , Jan Pilch
发明人： Jürgen Seibold , Erhard Müller , Karel Volenec , Petr Sittner , Ludek Heller , Jan Pilch
IPC分类号： A61F2/84 , A61F2/06 , A61F2/82
CPC分类号： A61F2/90 , A61F2/06 , A61F2/07 , A61F2002/075 , A61L31/022 , A61L31/10 , A61L31/14 , A61L2400/16 , C08L2201/12 , D02G3/36 , D02G3/448 , D03D3/02 , D03D13/004 , D03D13/008 , D03D15/0027 , D03D15/0077 , D03D27/00 , D10B2401/046 , D10B2509/06 , C08L67/02
摘要： A medical device includes yarns made of a shape memory material and polymer yarns, wherein the yarns made of said shape memory material include polymer sheathing.
摘要翻译：医疗装置包括由形状记忆材料和聚合物纱线制成的纱线，其中由所述形状记忆材料制成的纱线包括聚合物护套。

4. 发明申请

US20090214429A1 METHODS AND COMPOSITIONS RELATED TO TARGETING TUMORS AND WOUNDS 有权
标题翻译：与肿瘤和创伤相关的方法和组成
公开(公告)号：US20090214429A1
公开(公告)日：2009-08-27
申请号：US12162751
申请日：2007-02-05
申请人： Erkki Ruoslahti , Jan Pilch
发明人： Erkki Ruoslahti , Jan Pilch
IPC分类号： A61K49/00 , C07K7/06 , C07K7/50 , C12N7/00 , A61K38/36 , A61K38/08
CPC分类号： A61K49/0056 , A61K38/08 , A61K38/10 , A61K38/12 , A61K38/16 , A61K38/17 , A61K47/64 , A61K49/0043 , A61K49/085 , A61K49/14 , C07K7/06 , C07K7/64 , C07K14/00 , C07K2319/00 , C07K2319/01 , C07K2319/035
摘要： Disclosed are compositions and methods useful for targeting tumors, sites of injury and blood clots. The compositions and methods are based on peptide sequences that selectively bind to and home to tumors, sites of injury and blood clots in animals. The disclosed targeting is useful for delivering therapeutic and detectable agents to tumors, sites of injury and blood clots.
摘要翻译：公开了用于靶向肿瘤，损伤部位和血块的组合物和方法。组合物和方法基于肽序列，其选择性地结合和归属于动物的肿瘤，损伤部位和血块。所公开的靶向对于将治疗和可检测的药物递送到肿瘤，损伤部位和血块是有用的。

5. 发明授权

US08815804B2 Methods and compositions related to targeting tumors and wounds 有权
标题翻译：与靶向肿瘤和创伤相关的方法和组合
公开(公告)号：US08815804B2
公开(公告)日：2014-08-26
申请号：US12162751
申请日：2007-02-05
申请人： Erkki Ruoslahti , Jan Pilch
发明人： Erkki Ruoslahti , Jan Pilch
IPC分类号： C07K7/00 , C07K7/06 , C07K7/64 , C07K14/47 , A61K38/08 , A61K38/12 , A61K38/16 , A61K38/17 , A61K51/08 , A61K49/00 , A61K49/08 , A61K49/14 , A61K47/48
CPC分类号： A61K49/0056 , A61K38/08 , A61K38/10 , A61K38/12 , A61K38/16 , A61K38/17 , A61K47/64 , A61K49/0043 , A61K49/085 , A61K49/14 , C07K7/06 , C07K7/64 , C07K14/00 , C07K2319/00 , C07K2319/01 , C07K2319/035
摘要： Disclosed are compositions and methods useful for targeting tumors, sites of injury and blood clots. The compositions and methods are based on peptide sequences that selectively bind to and home to tumors, sites of injury and blood clots in animals. The disclosed targeting is useful for delivering therapeutic and detectable agents to tumors, sites of injury and blood clots.
摘要翻译：公开了用于靶向肿瘤，损伤部位和血块的组合物和方法。组合物和方法基于肽序列，其选择性地结合和归属于动物的肿瘤，损伤部位和血块。所公开的靶向对于将治疗和可检测的药物递送到肿瘤，损伤部位和血块是有用的。

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