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    • 2. 发明授权
    • Potentiated topical composition
    • 强化局部组合物
    • US08642053B2
    • 2014-02-04
    • US10491992
    • 2002-10-18
    • Jan FaergemannThomas Hedner
    • Jan FaergemannThomas Hedner
    • A61K8/02
    • A61K8/345A61K8/0208A61K9/0014A61K47/10A61Q1/06A61Q19/00A61Q19/007
    • A topical composition for skin care or administration of a pharmacologically active agent in form of a lotion, cream or similar comprises from 5% to 70% by weight of pentane-1,5-diol and a cosmetically or pharmaceutically acceptable carrier, with the proviso that the composition does not comprise polysiloxane, volatile siloxane, phosphatidyl-choline, creatine, carnitine, panthenol, pyruvic acid, monoglyceride of lauric acid, monoglyceride of myristic acid. Also disclosed are corresponding methods of administration, a patch for holding said composition against the skin, and methods of preventing or treating a dry skin condition and of keeping skin in a humid state.
    • 用于皮肤护理或施用洗剂,乳膏或类似物形式的药理活性剂的局部组合物包含5重量%至70重量%的戊烷-1,5-二醇和化妆品或药学上可接受的载体,其条件是 该组合物不包含肉豆蔻酸的聚硅氧烷,挥发性硅氧烷,磷脂酰胆碱,肌酸,肉毒碱,泛醇,丙酮酸,月桂酸单甘油酯,单酸甘油酯。 还公开了相应的施用方法,用于将所述组合物保持在皮肤上的贴剂,以及预防或治疗干性皮肤状况并保持皮肤处于潮湿状态的方法。