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1. 发明申请

US20090030310A1 Diagnostic probe for combining positron emission measurements with ultrasonography 审中-公开
标题翻译：用于将正电子发射测量与超声检查结合的诊断探针
公开(公告)号：US20090030310A1
公开(公告)日：2009-01-29
申请号：US11881342
申请日：2007-07-26
申请人： James J. Hamill , David D. Faul , William Curtis Howe
发明人： James J. Hamill , David D. Faul , William Curtis Howe
IPC分类号： A61B6/00 , A61B8/00
CPC分类号： A61B8/12 , A61B6/037 , A61B6/4258 , A61B6/4417 , A61B8/4416 , G01T1/161
摘要： A system for dual-mode medical imaging is provided. The system features components for PET imaging as well as for ultrasonic imaging, with an internal probe that has components to provide capability for both. The system provides cost-efficient PET imaging for smaller regions and organs of interest than conventional full body PET scanner apparatus.
摘要翻译：提供了一种双模式医学成像系统。该系统具有用于PET成像以及超声成像的组件，内部探针具有为两者提供能力的组件。该系统为传统全身PET扫描仪装置的较小区域和器官提供了具有成本效益的PET成像。

2. 发明授权

US06774358B2 Normalization apparatus for PET and SPECT scanners and method for using same 失效
标题翻译： PET和SPECT扫描仪的归一化装置及其使用方法
公开(公告)号：US06774358B2
公开(公告)日：2004-08-10
申请号：US10103276
申请日：2002-03-21
申请人： James J. Hamill , Michael E. Casey , Timothy G. Gremillion , Wing K. Luk , Stephen Miller
发明人： James J. Hamill , Michael E. Casey , Timothy G. Gremillion , Wing K. Luk , Stephen Miller
IPC分类号： G01K500
CPC分类号： G01T1/2985 , A61B6/037 , G01T1/1644
摘要： Apparatus and methods for simulating a sheet source with a line source for determining normalization coefficients for the detectors in positron emission tomography (PET) scanners and single photon emission computed tomography (SPECT) scanners. A line source, oriented perpendicular to the axis of a scanner gantry, is moved along the axis while the detectors are stationary and positioned substantially parallel to the plane in which the source moves. In another embodiment, an axially mounted line source moves parallel to a diameter of the gantry while the stationary detectors are positioned substantially parallel to the plane in which the source moves. In still another embodiment, the line source is stationary and positioned parallel to the gantry axis and off center while the detectors move relative to the line source. A shaped attenuator is placed around the source in this last embodiment.
摘要翻译：用于模拟具有用于确定正电子发射断层摄影（PET）扫描仪和单光子发射计算机断层摄影（SPECT）扫描仪中的检测器的归一化系数的线源的片材源的装置和方法。垂直于扫描仪台架的轴线定向的线源沿轴线移动，同时检测器是固定的并且基本上平行于源移动的平面定位。在另一个实施例中，轴向安装的线源平行于台架的直径移动，而固定检测器基本上平行于源移动的平面定位。在另一个实施例中，线源固定并且平行于台架轴定位并且离开中心，同时检测器相对于线源移动。在最后一个实施例中，围绕源设置成形的衰减器。

3. 发明授权

US5757006A Articulating detector array for a gamma camera 失效
标题翻译：用于伽马相机的铰接式探测器阵列
公开(公告)号：US5757006A
公开(公告)日：1998-05-26
申请号：US790833
申请日：1997-01-30
申请人： Raymond P. DeVito , James J. Hamill
发明人： Raymond P. DeVito , James J. Hamill
IPC分类号： G01T1/164 , G01T1/24 , G01T1/161
CPC分类号： G01T1/1642 , G01T1/249 , A61B6/037
摘要： An articulating detector array for gamma cameras is disclosed which is adaptable to perform different imaging techniques in a single apparatus. The articulating detector array is adapted to detect incident gamma radiation from diverse directions as well as Compton scattering thereof without the need of a collimator, as so has improved gamma ray detection efficiency. The detector array includes radiation detectors in an array and movable to a plurality of positions, in which each radiation detector is responsive to gamma radiation from a target for generating detection signals for use in tomographic imaging of the source. The detector array includes articulating support structures for mounting the detectors to the base and for moving the detectors from a first position to a second position. In one embodiment, the articulating support structures includes a first portion connected to a detector; and a second portion connected to the base, in which the first portion is adapted to extend from the second portion from the first position to the second position. In another embodiment, the articulating support structures include a pivot for pivotably mounting the detectors and for rotating the detectors from a first position to a second position.
摘要翻译：公开了一种用于伽马照相机的关节式检测器阵列，其适用于在单个装置中执行不同的成像技术。铰接检测器阵列适于从不同方向检测入射伽马射线以及其康普顿散射，而不需要准直器，因此伽马射线检测效率得到改善。检测器阵列包括阵列中的辐射检测器并且可移动到多个位置，其中每个辐射检测器响应来自目标的伽马射线，用于产生用于源的断层成像的检测信号。检测器阵列包括用于将检测器安装到基座并用于将检测器从第一位置移动到第二位置的铰接支撑结构。在一个实施例中，铰接支撑结构包括连接到检测器的第一部分; 以及连接到所述基座的第二部分，其中所述第一部分适于从所述第二部分从所述第一位置延伸到所述第二位置。在另一个实施例中，铰接支撑结构包括用于可枢转地安装检测器并用于将检测器从第一位置转动到第二位置的枢轴。

4. 发明授权

US10186337B2 Compact radioisotope generator 有权
公开(公告)号：US10186337B2
公开(公告)日：2019-01-22
申请号：US12887933
申请日：2010-09-22
申请人： James J. Hamill , Stefan B. Siegel , Charles Russell Buchanan
发明人： James J. Hamill , Stefan B. Siegel , Charles Russell Buchanan
IPC分类号： G21G1/06 , G21G1/00
摘要： A method and apparatus for making a radioisotope and a composition of matter including the radioisotope. The radioisotope is made by exposing a material to neutrons from a portable neutron source. More specifically, a solution includes a particular isotope. The neutron source is completely surrounded by the solution. The solution is exposed to the neutrons. Generated radioisotopes are extracted from the solution.

5. 发明授权

US09456791B2 System and method for constraining a computerized tomography patient 有权
标题翻译：用于约束计算机断层摄影患者的系统和方法
公开(公告)号：US09456791B2
公开(公告)日：2016-10-04
申请号：US12558159
申请日：2009-09-11
申请人： James J. Hamill , Carl Eric Arnsdorff
发明人： James J. Hamill , Carl Eric Arnsdorff
IPC分类号： A61G15/00 , A61B6/03 , A61B6/04 , A61B5/103 , A61B6/00
CPC分类号： A61B6/037 , A61B5/103 , A61B6/0421 , A61B6/482
摘要： A constraint having a main body and at least one coupler. The main body can be substantially arcuate in shape and can be configured to constrain a patient. The at least one coupler can couple the main body to a bed or treatment pallet. The constraint can be sized to restrict a patient within a computerized tomography (CT) scan field of view.
摘要翻译：具有主体和至少一个耦合器的约束。主体可以是基本上弓形的形状，并且可以构造成约束患者。所述至少一个联接器可以将主体连接到床或处理托盘。该约束的大小可以限制在计算机断层摄影（CT）扫描视野内的患者。

6. 发明授权

US07769217B2 Fast iterative 3D PET image reconstruction using a set of 2D linogram transformations 失效
标题翻译：快速迭代3D PET图像重建使用一组二维线条图变换
公开(公告)号：US07769217B2
公开(公告)日：2010-08-03
申请号：US11714406
申请日：2007-03-06
申请人： James J. Hamill
发明人： James J. Hamill
IPC分类号： G06K9/00
CPC分类号： G06T11/006 , G06T2211/424
摘要： A method for performing accurate iterative reconstruction of three dimensional image data sets based on Approximate Discrete Radon Transformation (ADRT) using two dimensional linograms for each of a plurality of defined planes tilted from the (x, y, 0) plane by a tilt angle and orientation angle. Image data is arranged with respect to the defined tilted planes ADRT and its inverse are implemented to provide exactly matched forward and backward projectors suitable for the Maximum-Likelihood Expectation-Maximization (ML-EM) reconstruction in PET. An EM reconstruction algorithm is accomplished by initializing an estimation image.
摘要翻译：一种用于基于近似离散氡变换（ADRT）对三维图像数据集进行精确迭代重建的方法，所述方法使用用于从（x，y，0）平面倾斜倾斜角度的多个限定平面中的每一个定义的平面使用二维立体图，取向角度。图像数据相对于定义的倾斜平面ADRT布置，并且其反向被实现以提供适合于PET中的最大似然期望最大化（ML-EM）重建的精确匹配的前向和后向投影仪。通过初始化估计图像来实现EM重建算法。

7. 发明授权

US07483518B2 Apparatus and method for rapidly switching the energy spectrum of diagnostic X-ray beams 失效
标题翻译：用于快速切换诊断X射线束的能谱的装置和方法
公开(公告)号：US07483518B2
公开(公告)日：2009-01-27
申请号：US11519410
申请日：2006-09-12
申请人： James J. Hamill
发明人： James J. Hamill
IPC分类号： H01J35/10 , H01J35/00 , G21K3/00
CPC分类号： H01J35/18 , G21K1/10 , H01J35/305 , H01J2235/183
摘要： An X-ray imaging apparatus is disclosed. The apparatus includes a radiator housing, an X-ray tube, a source of X-rays and at least one filtration material disposed on the X-ray tube. The X-ray tube is rotatable about a longitudinal axis and is disposed at least partially within the radiator housing. The source of X-rays emits at least one X-ray beam at least partially through the X-ray tube. The X-ray beam exits the X-ray tube at an annular X-ray window. The filtration material at least partially covers a portion of the annular X-ray window. Rotation of the X-ray tube causes the X-ray beam to pass through a plurality of locations in the annular X-ray window and at least a portion of the X-ray beam is filtered by the filtration material.
摘要翻译：公开了一种X射线成像装置。该装置包括散热器壳体，X射线管，X射线源和设置在X射线管上的至少一个过滤材料。 X射线管可以围绕纵向轴线旋转并且至少部分地设置在散热器壳体内。 X射线源至少部分地通过X射线管发射至少一个X射线束。 X射线束以环形X射线窗口离开X射线管。过滤材料至少部分地覆盖环形X射线窗口的一部分。 X射线管的旋转导致X射线束穿过环形X射线窗口中的多个位置，X射线束的至少一部分被过滤材料过滤。

8. 发明申请

US20080063145A1 Apparatus and method for rapidly switching the energy spectrum of diagnostic X-ray beams 失效
标题翻译：用于快速切换诊断X射线束的能谱的装置和方法
公开(公告)号：US20080063145A1
公开(公告)日：2008-03-13
申请号：US11519410
申请日：2006-09-12
申请人： James J. Hamill
发明人： James J. Hamill
IPC分类号： H01J35/10
CPC分类号： H01J35/18 , G21K1/10 , H01J35/305 , H01J2235/183
摘要： An X-ray imaging apparatus is disclosed. The apparatus includes a radiator housing, an X-ray tube, a source of X-rays and at least one filtration material disposed on the X-ray tube. The X-ray tube is rotatable about a longitudinal axis and is disposed at least partially within the radiator housing. The source of X-rays emits at least one X-ray beam at least partially through the X-ray tube. The X-ray beam exits the X-ray tube at an annular X-ray window. The filtration material at least partially covers a portion of the annular X-ray window. Rotation of the X-ray tube causes the X-ray beam to pass through a plurality of locations in the annular X-ray window and at least a portion of the X-ray beam is filtered by the filtration material.
摘要翻译：公开了一种X射线成像装置。该装置包括散热器壳体，X射线管，X射线源和设置在X射线管上的至少一个过滤材料。 X射线管可以围绕纵向轴线旋转并且至少部分地设置在散热器壳体内。 X射线源至少部分地通过X射线管发射至少一个X射线束。 X射线束以环形X射线窗口离开X射线管。过滤材料至少部分地覆盖环形X射线窗口的一部分。 X射线管的旋转导致X射线束穿过环形X射线窗口中的多个位置，X射线束的至少一部分被过滤材料过滤。

9. 发明申请

US20140051977A9 Optimal Respiratory Gating In Medical Imaging 有权
标题翻译：医学影像中的最佳呼吸门控
公开(公告)号：US20140051977A9
公开(公告)日：2014-02-20
申请号：US13248089
申请日：2011-09-29
申请人： James J. Hamill , Ludovic Le Meunier
发明人： James J. Hamill , Ludovic Le Meunier
IPC分类号： A61B5/055 , A61B5/05
CPC分类号： A61B5/7292 , A61B5/1135 , A61B6/037 , A61B6/541 , G01R33/481 , G01R33/5676
摘要： Methods and computer-readable mediums are provided for obtaining an optimally gated medical image. For example, in one embodiment, a method is provided that acquires medical images in list mode. The method also acquires a respiration correlated signal S(t). Thereafter, a final upper strain threshold value and a final lower strain threshold value pair that has a narrowest interval are selected. The medical images are synchronized with the respiration correlated signal S(t). The synchronized images and signal are used to create an optimally gated medical image. In various embodiments, the disclosed optimal gating can be utilized in PET systems and in other embodiments the disclosed optimal gating can be utilized in SPECT systems. In yet other embodiments, the optimally gated images can be matched to MRI systems and in still other embodiments, the optimally gated images can be matched to CT systems.
摘要翻译：提供方法和计算机可读介质以获得最佳门控的医学图像。例如，在一个实施例中，提供了以列表模式获取医学图像的方法。该方法还获取呼吸相关信号S（t）。此后，选择具有最窄间隔的最终上应变阈值和最终下应变阈值对。医学图像与呼吸相关信号S（t）同步。同步的图像和信号用于创建最佳门控的医学图像。在各种实施例中，所公开的最佳选通可用于PET系统中，并且在其它实施例中，所公开的最佳门控可用于SPECT系统。在其他实施例中，最佳门控图像可以与MRI系统匹配，并且在其他实施例中，最佳门控图像可以与CT系统匹配。

10. 发明授权

US08565856B2 Ultrasonic imager for motion measurement in multi-modality emission imaging 有权
标题翻译：超声波成像仪用于多模式发射成像中的运动测量
公开(公告)号：US08565856B2
公开(公告)日：2013-10-22
申请号：US12125329
申请日：2008-05-22
申请人： James J. Hamill , Günther Platsch , Michael E. Casey
发明人： James J. Hamill , Günther Platsch , Michael E. Casey
IPC分类号： A61B5/05
CPC分类号： A61B8/08 , A61B5/7285 , A61B6/032 , A61B6/5247 , A61B6/541 , A61B8/4245 , A61B8/5238 , A61B8/543 , G01T1/1603
摘要： A medical imaging device has an emission tomograph, at least one ultrasonic (US) probe for providing images giving real-time information about the location of the internal organs of a subject, a tracking system for spatially locating the at least one ultrasonic probe in relation to the medical imaging device, and an image processing unit in which the location information obtained by the ultrasonic probe is used for attenuation correction of image information obtained by the emission tomograph.
摘要翻译：一种医疗成像装置具有发射断层摄影机，至少一个超声波（US）探头，用于提供给出关于被检体的内部器官的位置的实时信息的图像，用于相对于空间定位至少一个超声波探头的跟踪系统以及图像处理单元，其中由超声波探头获得的位置信息用于由发射断层摄影机获得的图像信息的衰减校正。

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