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1. 发明授权

US06544196B2 Estrogen or estradiol need determination by vaginal or urethral acidity determination 失效
公开(公告)号：US06544196B2
公开(公告)日：2003-04-08
申请号：US09838371
申请日：2001-04-20
申请人： James C. Caillouette
发明人： James C. Caillouette
IPC分类号： A61B500
CPC分类号： A61B5/14539 , A61B5/00 , A61B5/4294 , A61B5/4337 , A61B10/0012 , A61B10/0048 , A61B10/0291 , A61B2010/0074 , A63F2011/0018 , G01N33/528 , G01N33/84
摘要： In the method of determining need for human estrogen replacement therapy or estrogen or estradiol dose change, the steps include determining local acidity proximate a moist wall surface of the vagina, or urethra, as differing from desired threshold level (pH 4.5), and administering sufficient estrogen or estradiol to result in change in acidity toward such level.

2. 发明授权

US06390991B1 Vaginal moisture test apparatus and method 失效
标题翻译：阴道湿度试验装置及方法
公开(公告)号：US06390991B1
公开(公告)日：2002-05-21
申请号：US09722212
申请日：2000-11-27
申请人： James C. Caillouette
发明人： James C. Caillouette
IPC分类号： A61B500
CPC分类号： A61B10/02 , A61B5/14507 , A61B5/14539 , A61B5/4294 , A61B5/4337 , A61B10/0012 , A61B10/0045 , A61B10/0048 , A61B10/0291 , A61B2010/0074 , A61B2090/037 , A61M35/003 , G01N31/221 , G01N33/528 , G01N33/84
摘要： A method for detecting pH of vaginal or urethral moisture, the steps that include providing an elongated carrier; providing a pH detector on the carrier; providing a moisture receiver in association with the carrier, and via which a sample of vaginal or urethral moisture is applicable to a detector to effect a changed color thereof; and providing a pH correlating color comparison means in sufficiently close association with the detector to allow visual comparison of the changed color exhibited by the detector with a pH correlated color provided by measurement means.
摘要翻译：一种用于检测阴道或尿道水分的pH的方法，所述步骤包括提供细长的载体; 在载体上提供pH值检测器; 提供与载体相关联的湿气接收器，通过其将阴道或尿道水分的样品应用于检测器以实现其变色; 以及提供与检测器充分紧密关联的pH相关色彩比较装置，以便将由检测器显示的改变的颜色与由测量装置提供的pH相关颜色进行目视比较。

3. 发明授权

US6066124A Control of treatment fluid application to tissue 有权
标题翻译：控制治疗液应用于组织
公开(公告)号：US6066124A
公开(公告)日：2000-05-23
申请号：US199208
申请日：1998-11-24
申请人： James C. Caillouette
发明人： James C. Caillouette
IPC分类号： A61M35/00 , A61M31/00
CPC分类号： A61M35/003
摘要： The method of applying screening or treatment fluid to tissue, and employing an elongated carrier, having a first end portion; a flexible outer container having a generally tubular second end portion and a frangible inner container protectively located within the outer container, there being screening or treatment fluid within the inner container, and a fluid applicator carried by the flexible outer container, to communicate with the interior of the outer container which includes a connector having a body defining oppositely projecting third and fourth end portions, and interfitting the third and fourth end portions with the first and second end portions, respectively, so that the elongated carrier is substantially rigidly joined to first end portion of the flexible outer container, exerting pressure on a pressure application region of the outer container spaced from the connector body, and sufficient to rupture the inner container, thereby releasing screening or treatment fluid into the interior of the outer container, enabling fluid migration to the applicator; and manipulating the elongated carrier thereby to manipulate the outer container when inserted into the body cavity, and by force transmission via the connector body, to cause the applicator to controllably apply screening or treatment fluid to tissue in a cavity.
摘要翻译：将筛选或处理流体施加到组织并使用具有第一端部的细长载体的方法; 柔性外部容器具有大致管状的第二端部和保护性地定位在外部容器内的易碎内部容器，在内部容器内具有筛分或处理流体，以及由柔性外部容器承载的与内部连通的流体施加器所述外部容器包括具有限定相对突出的第三和第四端部的主体的连接器，并且分别将第三和第四端部与第一和第二端部相互配合，使得细长的载体基本上刚性地连接到第一端柔性外容器的一部分，在与容器隔开的外容器的压力施加区域上施加压力，并且足以使内容器破裂，从而将筛分或处理流体释放到外容器的内部，涂抹器; 并且操纵细长的载体，从而当插入到体腔中时操纵外部容器，并且通过经由连接器主体的力传递，使得施加器可控地将筛选或处理流体施加到空腔中的组织。

4. 发明授权

US5762614A Estrogen or estradiol need determination by vaginal acidity determination 失效
公开(公告)号：US5762614A
公开(公告)日：1998-06-09
申请号：US570534
申请日：1995-12-11
申请人： James C. Caillouette
发明人： James C. Caillouette
IPC分类号： A61B5/00 , A61B10/00 , A61B10/02 , A63F9/00 , A63F11/00 , G01N33/52 , G01N33/84
CPC分类号： G01N33/84 , A61B10/0012 , A61B5/00 , A61B5/14507 , A61B5/14539 , A61B5/4294 , A61B5/4337 , G01N33/528 , A61B10/0048 , A61B10/0291 , A61B2010/0074 , A63F2011/0018
摘要： In the method of determining need for human estrogen or estradiol level change, the steps include determining local acidity proximate a moist wall surface of the vagina, as differing from desired threshold level, and administering sufficient estrogen or estradiol to result in change in acidity toward such level.

5. 发明授权

US5577512A pH detection and measurement of body fluid 失效
标题翻译： pH检测和体液测量
公开(公告)号：US5577512A
公开(公告)日：1996-11-26
申请号：US537379
申请日：1995-10-27
申请人： James C. Caillouette
发明人： James C. Caillouette
IPC分类号： A61B5/00 , A61B10/00 , A61B10/02 , A63F9/00 , A63F11/00 , G01N33/52 , G01N33/84
CPC分类号： G01N33/528 , A61B5/14507 , A61B5/14539 , A61B5/4294 , A61B5/4337 , G01N33/84 , A61B10/0012 , A61B10/0048 , A61B10/0291 , A61B2010/0074 , A63F2011/0018
摘要： In the method of detecting pH of vaginal moisture, the steps that include providing a pH detection structure on a carrier stick; providing a protective porous layer adjacent the pH detection structure; manipulating the stick to obtain pH detection of vaginal moisture; and including allowing vaginal moisture to penetrate the porous layer for contact with the pH detection structure, and visually observing the detection structure.
摘要翻译：在检测阴道水分pH的方法中，包括在载体棒上提供pH检测结构的步骤; 提供邻近pH检测结构的保护性多孔层; 操纵棒以获得阴道水分的pH检测; 并且包括允许阴道水分穿透多孔层以与pH检测结构接触，并且目视观察检测结构。

6. 发明授权

US5425377A pH measurement of body fluid 失效
标题翻译：体液的pH测量
公开(公告)号：US5425377A
公开(公告)日：1995-06-20
申请号：US295399
申请日：1994-08-25
申请人： James C. Caillouette
发明人： James C. Caillouette
IPC分类号： A61B5/00 , A61B10/00 , A61B10/02 , G01N33/52 , G01N33/84
CPC分类号： G01N33/84 , A61B5/14507 , A61B5/14539 , A61B5/4294 , A61B5/4337 , G01N33/528 , A61B10/0012 , A61B10/0048 , A61B10/0291 , A61B2010/0074
摘要： The method of measuring pH of vaginal moisture, which includes providing a pH indication, color comparison measurement, and swabbing structure on a carrier stick; manipulating the stick between its opposite ends, to obtain pH indication of vaginal moisture at one end of the stick; visually interpreting that indication to also obtain pH measurement of such moisture near that one end of the stick; again manipulating the stick between its opposite ends, including endwise reversing it, to swab the vaginal cavity in the area from which pH indication was obtained; and disposing of the stick, whereby disposition of the pH indication, measurement and swabbing structure is thereby obtained in one disposal step.
摘要翻译：测量阴道水分pH的方法，包括在载体棒上提供pH指示，颜色比较测量和擦拭结构; 操纵其两端之间的棒，以获得棒的一端的阴道水分的pH指示; 视觉上解释该指示，以便在棒的一端附近获得这种水分的pH测量; 再次操纵其相对端之间的棒，包括使其端部反向，以在从其获得pH指示的区域中拭取阴道腔; 并且由此在一个处置步骤中获得pH值指示，测量和擦拭结构的布置。

7. 发明授权

US5342331A Toxicity resistant tampon structure 失效
标题翻译：抗毒性棉塞结构
公开(公告)号：US5342331A
公开(公告)日：1994-08-30
申请号：US2642
申请日：1993-01-11
申请人： Arthur L. Silber , Raymond C. Ng , James C. Caillouette
发明人： Arthur L. Silber , Raymond C. Ng , James C. Caillouette
IPC分类号： A61F5/455 , A61F13/15 , A61F13/20 , A61F13/34
CPC分类号： A61F5/4553 , A61F13/2051 , A61F13/34 , A61F13/202 , A61F2013/15081 , Y10S604/904
摘要： A flow-controlling tampon, comprising a generally upright elongated sheath structure having an open upper end and a closed lower end, the upper end sized to fit about the cervix an inner, elongated, flow-control tube extending generally upright within the sheath, the tube having an upper open end to receive flow via the upper open end of the sheath, and the flow-control tube having lower opening structure to pass flow from the tube into the lower interior of the sheath to gradually collect upwardly from the lower interior of the sheath, and about the control tube.
摘要翻译：一种流动控制棉塞，其包括具有敞开的上端和封闭的下端的大致直立的细长护套结构，所述上端的尺寸适于围绕所述子宫颈安装一个在所述护套内大致直立延伸的内部细长的流动控制管，管具有上开口端以接收经由护套的上开口端的流动，并且流动控制管具有较低的开口结构，以将来自管的流体流入护套的下部内部，以逐渐从下部内部收集护套和控制管周围。

8. 外观设计

USD678545S1 pH determination device 有权
标题翻译： pH测定装置
公开(公告)号：USD678545S1
公开(公告)日：2013-03-19
申请号：US29374837
申请日：2011-10-14
申请人： James C. Caillouette
设计人： James C. Caillouette

9. 发明授权

US06409681B1 Estrogen or estradiol need determination by vaginal or urethral acidity determination 失效
标题翻译：雌激素或雌二醇需要通过阴道或尿道酸度测定来确定
公开(公告)号：US06409681B1
公开(公告)日：2002-06-25
申请号：US09556747
申请日：2000-04-21
申请人： James C. Caillouette
发明人： James C. Caillouette
IPC分类号： A61B500
CPC分类号： G01N33/84 , A61B5/14507 , A61B5/14539 , A61B5/4294 , A61B5/4337 , A61B10/0012 , A61B10/0048 , A61B10/0291 , A61B2010/0074 , G01N33/528
摘要： In the method of determining need for human estrogen replacement therapy or estrogen or estradiol dose change, the steps include determining local acidity proximate a moist wall surface of the vagina, or urethra, as differing from desired threshold level (pH 4.5), and administering sufficient estrogen or estradiol to result in change in acidity toward such level.
摘要翻译：在确定人雌激素替代疗法或雌激素或雌二醇剂量变化的需要的方法中，步骤包括确定与阴性或尿道的潮湿壁表面相邻的局部酸度，其与期望的阈值水平（pH4.5）不同，并且足够施用雌激素或雌二醇导致酸度向这样的水平变化。

10. 发明授权

US06402705B1 Body moisture test apparatus and method 失效
标题翻译：身体水分测试仪器及方法
公开(公告)号：US06402705B1
公开(公告)日：2002-06-11
申请号：US09436332
申请日：1999-11-08
申请人： James C. Caillouette
发明人： James C. Caillouette
IPC分类号： A61B500
CPC分类号： G01N33/84 , A61B5/00 , A61B5/14507 , A61B5/14539 , A61B5/4283 , A61B5/4294 , A61B5/4318 , A61B5/4337 , A61B10/0012 , A61B10/0045 , A61B10/0048 , A61B10/0291 , A61B2010/0074 , A63F2011/0018 , G01N33/528
摘要： In the method of measuring pH of vaginal or other tissue moisture, the steps that include providing an indicator that exhibits a characteristic color when contacted with the moisture, the color being a function of moisture pH; obtaining a vaginal or other tissue moisture sample and transferring moisture from the sample to an indicator, outside the body, whereby the indicator then exhibits a characteristic color, which is a function of pH of the moisture; and providing a color comparison measurement means, and comparing the indicator characteristic color with color comparison measurement means. Also provided are test kit structures to enable performance of such pH measurement, as used for estrogen need determination and the presence or absence of amniotic fluid; and also to determine presence of amines produced by pathogenic bacteria, or flagellates (trichomonas).
摘要翻译：在测量阴道或其他组织湿度的pH的方法中，包括提供当与水分接触时呈现特征颜色的指示剂的步骤，颜色是水分pH的函数; 获得阴道或其他组织水分样品，并将水分从样品转移到身体外的指示剂，由此指示剂随后表现出特征性颜色，其是水分的pH值的函数; 以及提供颜色比较测量装置，并将指示符特征颜色与颜色比较测量装置进行比较。还提供了测试试剂盒结构，以使得能够进行这样的pH测量，用于雌激素需要测定和羊水的存在或不存在; 并且还确定由致病细菌产生的胺或鞭毛虫（毛滴虫）的存在。

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