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1. 发明申请

WO2021205203A1 TEXTILE UPHOLSTERED INFLATABLE FLOATING LOUNGER FOR SUPPORTING AN INDIVIDUAL OR OBJECT IN WATER 审中-公开
公开(公告)号：WO2021205203A1
公开(公告)日：2021-10-14
申请号：PCT/IB2020/053290
申请日：2020-04-07
申请人： MICKLEWRIGHT, Oliver James Berger
发明人： MICKLEWRIGHT, Oliver James Berger
IPC分类号： A47C15/00 , A47C27/08 , B63B34/52 , A47C1/14 , A47C4/54
摘要： According to a first aspect, the invention relates to a floating lounger (1) for supporting an individual or objects in water. The lounger (1) comprises a buoyant core (2) which is made of a plastic film inflatable. The buoyant core (3) is upholstered in a textile layer (3) on the outside.

2. 发明申请

WO1998051303A1 HIV AND CANCER TREATMENT 审中-公开
标题翻译：艾滋病毒和癌症治疗
公开(公告)号：WO1998051303A1
公开(公告)日：1998-11-19
申请号：PCT/US1997021564
申请日：1997-11-26
申请人： THE PROCTER & GAMBLE COMPANY , CAMDEN, James, Berger
发明人： THE PROCTER & GAMBLE COMPANY
IPC分类号： A61K31/41
CPC分类号： A61K31/662 , A61K31/27 , A61K31/4184 , A61K31/4196 , A61K31/427 , A61K45/06
摘要： A method of treating HIV or other viral infections by administering a herbicide or fungicide or derivative thereof to an animal or human. The fungicides or herbicides can be used in conjunction with other treatments, e.g. with AZT or protease inhibitors for the treatment of HIV. For example, thiabendazole and chloropropham have been shown to quickly reduce the level of virus production from cell populations chronically infected with HIV-1 and the antiviral effect is maintained with continued compound exposure. This reduction of virus production occurs at concentrations which are non toxic to the host cell and which have no effect on the syntheses of cellular DNA, RNA and protein. Further, chronically infected cells treated for prolonged periods of time with thiabendazole and chloropropham were not super-infected with HIV. A method for inhibiting the growth of tumors and cancers in mammals comprising administering a herbicidal or fungicidal derivative is also disclosed herein. The fungicides or herbicides can be used in conjunction with other treatments, e.g. taxol for the treatment of breast cancer. Potentiators can also be included in the herbicidal or fungicidal composition. This method is particularly effective when the cancer or virus is an animal cell genetically modified by plant or fungus genetic material. A chemotherapeutic agent can also be administered first to significantly reduce the size of the cancer and then the treatment with the herbicide or fungicide is used. These methods are particularly effective when the cancer or virus is a mutated cell comprising plant or fungal genetic material.
摘要翻译：一种通过向动物或人施用除草剂或杀真菌剂或其衍生物来治疗HIV或其它病毒感染的方法。杀真菌剂或除草剂可以与其它处理结合使用，例如用AZT或蛋白酶抑制剂治疗HIV。例如，已经显示噻苯达唑和氯敌菌素可以快速降低长期感染HIV-1的细胞群体的病毒产生水平，并且持续的化合物暴露可以维持抗病毒作用。病毒生产的这种减少发生在对宿主细胞无毒且对细胞DNA，RNA和蛋白质的合成没有影响的浓度。此外，长期使用噻替达唑和氯敌霉素治疗的慢性感染细胞未感染艾滋病毒。抑制哺乳动物肿瘤和癌症生长的方法包括施用除草或杀真菌衍生物。杀真菌剂或除草剂可以与其它处理结合使用，例如紫杉醇用于治疗乳腺癌。加药剂也可以包含在除草或杀真菌组合物中。当癌症或病毒是由植物或真菌遗传物质遗传修饰的动物细胞时，该方法特别有效。也可以首先施用化学治疗剂以显着减少癌症的大小，然后使用除草剂或杀真菌剂进行治疗。当癌症或病毒是包含植物或真菌遗传物质的突变细胞时，这些方法特别有效。

3. 发明申请

US20070209572A1 HIGH THROUGHPUT SCREENING OF CRYSTALLIZATION MATERIALS 有权
标题翻译：结晶材料的高通量筛选
公开(公告)号：US20070209572A1
公开(公告)日：2007-09-13
申请号：US11668263
申请日：2007-01-29
申请人： Carl Hansen , Stephen Quake , James Berger
发明人： Carl Hansen , Stephen Quake , James Berger
IPC分类号： C30B7/10 , F17D1/08
CPC分类号： C30B7/08 , B01J2219/00274 , B01L3/06 , B01L3/502707 , B01L3/50273 , B01L3/502738 , B01L3/502761 , B01L7/54 , B01L9/527 , B01L2200/025 , B01L2200/027 , B01L2200/0605 , B01L2200/0642 , B01L2200/10 , B01L2300/0681 , B01L2300/0816 , B01L2300/0861 , B01L2300/0864 , B01L2300/0887 , B01L2300/123 , B01L2300/14 , B01L2300/18 , B01L2300/1827 , B01L2400/0481 , B01L2400/049 , B01L2400/0638 , B01L2400/0655 , B01L2400/0688 , C12Q1/6874 , C30B7/14 , F04B43/043 , F16K99/0001 , F16K99/0015 , F16K99/0026 , F16K99/0034 , F16K99/0059 , F16K2099/0074 , F16K2099/0078 , F16K2099/008 , F16K2099/0084 , F16K2099/0094 , Y10T117/1004 , Y10T117/1008 , Y10T137/0318 , Y10T137/0396 , C12Q2535/125
摘要： High throughput screening of crystallization of a target material is accomplished by simultaneously introducing a solution of the target material into a plurality of chambers of a microfabricated fluidic device. The microfabricated fluidic device is then manipulated to vary the solution condition in the chambers, thereby simultaneously providing a large number of crystallization environments. Control over changed solution conditions may result from a variety of techniques, including but not limited to metering volumes of crystallizing agent into the chamber by volume exclusion, by entrapment of volumes of crystallizing agent determined by the dimensions of the microfabricated structure, or by cross-channel injection of sample and crystallizing agent into an array of junctions defined by intersecting orthogonal flow channels.
摘要翻译：目标材料的结晶化的高通量筛选是通过将目标材料的溶液同时引入微细加工的流体装置的多个室来实现的。然后对微制造的流体装置进行操作以改变室中的溶液状态，从而同时提供大量的结晶环境。改变的溶液条件的控制可以由各种技术产生，包括但不限于通过体积排阻将结晶剂计量到室中的体积，通过捕获通过微结构结构的尺寸确定的结晶剂的体积，将样品和结晶剂通道注入由相交的正交流动通道限定的连接阵列。

4. 发明授权

US07072768B1 Method for laterally extrapolating soil property data using soil samples and seismic amplitude data within a seismic coverage area 失效
标题翻译：使用土壤样本和地震覆盖区域内的地震振幅数据横向外推土壤性状数据的方法
公开(公告)号：US07072768B1
公开(公告)日：2006-07-04
申请号：US10836680
申请日：2004-04-30
申请人： Alan G. Young , Philippe Jeanjean , Daniel Lee Lanier , Vernon Ray Kasch , John Richard Brand , William James Berger
发明人： Alan G. Young , Philippe Jeanjean , Daniel Lee Lanier , Vernon Ray Kasch , John Richard Brand , William James Berger
IPC分类号： G01V1/00
CPC分类号： G01V1/30
摘要： A method for laterally extrapolating shallow soil properties using soil samples and seismic amplitude data within a seismic coverage area entails obtaining seismic amplitude data for the seismic coverage area and obtaining average soil property and soil impedance data for locations in the seismic coverage area. The seismic amplitude data is compared with the soil impedance data at locations in the seismic coverage area forming an amplitude impendence formula. The seismic amplitude data is converted to soil-calibrated impedance data using the amplitude impendence formula. The method continues by comparing an average of desired soil property and the soil impedance data at locations in the seismic coverage area forming a soil property-impendence formula. A target soil property is selected and the soil calibrated impedance data is converted to the target soil property using the soil property impendence formula. The method ends by extrapolating the target soil property over the entire seismic coverage area.
摘要翻译：使用土壤样本和地震覆盖区域内的地震幅度数据横向外推浅层土壤性质的方法需要获得地震覆盖区域的地震幅度数据，并获得地震覆盖区域中的位置的平均土壤性质和土壤阻抗数据。将地震幅度数据与地震覆盖区域的土壤阻抗数据进行比较，形成幅度阻抗公式。使用振幅阻抗公式将地震幅度数据转换为土壤校准阻抗数据。该方法通过比较所需土壤性质的平均值和形成土壤性质 - 阻抗公式的地震覆盖区域中的土壤阻抗数据来继续。选择目标土壤性质，并使用土壤阻力公式将土壤校准阻抗数据转化为目标土壤性质。该方法结束于整个地震覆盖区域外推目标土壤性质。

5. 发明申请

US20050229839A1 High throughput screening of crystallization of materials 有权
标题翻译：高通量筛选材料结晶
公开(公告)号：US20050229839A1
公开(公告)日：2005-10-20
申请号：US11135923
申请日：2005-05-23
申请人： Stephen Quake , Carl Hansen , James Berger
发明人： Stephen Quake , Carl Hansen , James Berger
IPC分类号： B01D9/00 , B01J19/00 , B01L3/00 , B01L3/06 , B01L7/00 , B01L9/00 , B81B3/00 , B81C1/00 , C30B1/00 , F04B43/04 , F15C5/00 , F16K99/00
CPC分类号： C30B29/00 , B01D9/00 , B01D9/0072 , B01D9/0077 , B01J19/0046 , B01J2219/00274 , B01J2219/00286 , B01J2219/00317 , B01J2219/00389 , B01J2219/00418 , B01J2219/00432 , B01J2219/00585 , B01J2219/00756 , B01J2219/00891 , B01J2219/00907 , B01J2219/00952 , B01L3/06 , B01L3/5025 , B01L3/50273 , B01L3/502738 , B01L3/502753 , B01L7/54 , B01L9/527 , B01L2200/025 , B01L2200/027 , B01L2200/0605 , B01L2200/10 , B01L2300/0681 , B01L2300/0816 , B01L2300/0861 , B01L2300/123 , B01L2300/14 , B01L2300/18 , B01L2400/0481 , B01L2400/0655 , B01L2400/0688 , B81B2201/051 , B81B2201/054 , B81B2203/0127 , B81B2203/0315 , B81C1/00119 , B81C99/0065 , C30B7/14 , C30B29/54 , C30B29/58 , F04B43/043 , F16K99/0001 , F16K99/0015 , F16K99/0046 , F16K99/0051 , F16K99/0059 , F16K2099/0074 , F16K2099/0078 , F16K2099/008 , Y10T117/10 , Y10T117/1004 , Y10T117/1008 , Y10T117/1024
摘要： High throughput screening of crystallization of a target material is accomplished by simultaneously introducing a solution of the target material into a plurality of chambers of a microfabricated fluidic device. The microfabricated fluidic device is then manipulated to vary the solution condition in the chambers, thereby simultaneously providing a large number of crystallization environments. Control over changed solution conditions may result from a variety of techniques, including but not limited to metering volumes of crystallizing agent into the chamber by volume exclusion, by entrapment of volumes of crystallizing agent determined by the dimensions of the microfabricated structure, or by cross-channel injection of sample and crystallizing agent into an array of junctions defined by intersecting orthogonal flow channels.
摘要翻译：目标材料的结晶化的高通量筛选是通过将目标材料的溶液同时引入微细加工的流体装置的多个室来实现的。然后对微制造的流体装置进行操作以改变室中的溶液状态，从而同时提供大量的结晶环境。改变的溶液条件的控制可以由各种技术产生，包括但不限于通过体积排阻将结晶剂计量到室中的体积，通过捕获通过微结构结构的尺寸确定的结晶剂体积，将样品和结晶剂通道注入由相交的正交流动通道限定的连接阵列。

6. 发明授权

US06900235B1 Benzimidazole compounds, and pharmaceutical compositions and unit dosages thereof 失效
标题翻译：苯并咪唑化合物及其药物组合物及其单位剂量
公开(公告)号：US06900235B1
公开(公告)日：2005-05-31
申请号：US09676032
申请日：2000-09-29
申请人： Joseph K. Agyin , James C. Quada, Jr. , James Berger Camden
发明人： Joseph K. Agyin , James C. Quada, Jr. , James Berger Camden
IPC分类号： C07D235/32 , A61K31/415 , A61K31/4184 , A61P31/12 , A61P35/00
CPC分类号： A61K31/4184
摘要： Benzimidazole derivatives and salts and prodrugs thereof are disclosed, together with methods for the treatment of cancers or viral infections in warm blooded animals by administration of these compounds. Such compounds may be used in combination with a chemotherapeutic agent and/or a potentiator.
摘要翻译：公开了苯并咪唑衍生物及其盐和前药，以及通过施用这些化合物治疗温血动物中的癌症或病毒感染的方法。这样的化合物可以与化疗剂和/或增效剂组合使用。

7. 发明授权

US06608096B1 Compounds and methods for use thereof in the treatment of cancer or viral infections 失效
标题翻译：用于治疗癌症或病毒感染的化合物和方法
公开(公告)号：US06608096B1
公开(公告)日：2003-08-19
申请号：US09670166
申请日：2000-09-26
申请人： James Berger Camden , James C. Quada, Jr. , Joseph K. Agyin
发明人： James Berger Camden , James C. Quada, Jr. , Joseph K. Agyin
IPC分类号： A61K31415
CPC分类号： C07D235/32 , A61K31/4184 , C07D235/30
摘要： Benzimidazole derivatives and salts and prodrugs thereof are disclosed, together with methods for the treatment of cancers or viral infections in warm-blooded animals by administration of these compounds. Such compounds may be used in combination with a chemotherapeutic agent and/or a potentiator.
摘要翻译：公开了苯并咪唑衍生物及其盐和前药，以及通过施用这些化合物治疗温血动物中的癌症或病毒感染的方法。这样的化合物可以与化疗剂和/或增效剂组合使用。

8. 发明授权

US06410575B1 Viral treatment 有权
公开(公告)号：US06410575B1
公开(公告)日：2002-06-25
申请号：US09812094
申请日：2001-03-19
申请人： James Berger Camden
发明人： James Berger Camden
IPC分类号： A61K31433
摘要： A pharmaceutical composition that inhibits or slows the growth of viruses in animals, particularly in mammals, is disclosed. This same composition is can be used to treat viral infections, particularly hepatitis C, herpes simplex, Kaposi's sarcoma and HIV. The composition preferably comprises from about 10 mg to about 6000 mg of a (5-aryl-1,2,4-thiadiazol)-3-yl thiourea derivative or of the formula: wherein X is sulfur, R is hydrogen or alkyl having from 1-3 carbons, n is 0-4, R1 is independently selected from the group consisting of hydrogen, alkyl having from 1 to 7 carbon atoms, chloro, bromo or fluoro, oxychloro, alkoxy having the formula —O(CH2)yCH3 wherein y is from 1 to 6, or a pharmaceutically acceptable acid addition salt or prodrug thereof. The preferred compound is (5-phenyl-1,2,4-thiadazol-3-yl)thiourea.

9. 发明授权

US06384049B1 Cancer treatment 失效
标题翻译：癌症治疗
公开(公告)号：US06384049B1
公开(公告)日：2002-05-07
申请号：US09578281
申请日：2000-05-25
申请人： James Berger Camden
发明人： James Berger Camden
IPC分类号： A61K3144
CPC分类号： A61K45/06 , A61K31/437 , A61K2300/00
摘要： This invention is a method of treating cancer, including carcinomas and sarcomas through the administration of a pharmaceutical composition containing a pyridinylimidazole carbamate. The pyridinylimidazole carbamate is selected from the group consisting of: wherein X is independently selected from the group consisting of halo, for example, bromo, fluoro, chloro, iodo; hydroxyl, alkyl of less than 8 carbon atoms or alkoxy of less than 8 carbon atoms; n is a positive integer less than 4; R is hydrogen or an alkyl group of from 1 to 8 carbons and its pharmaceutically acceptable salts and prodrugs thereof.
摘要翻译：本发明是通过给药含有吡啶基咪唑氨基甲酸酯的药物组合物来治疗癌症的方法，包括癌和肉瘤。吡啶基咪唑氨基甲酸酯选自：其中X独立地选自卤素，例如溴，氟，氯，碘; 羟基，低于8个碳原子的烷基或小于8个碳原子的烷氧基; n是小于4的正整数; R是氢或1至8个碳的烷基及其药学上可接受的盐和前药。

10. 发明授权

US06228876B1 Pharmaceutical composition for inhibiting the growth of cancers 失效
标题翻译：用于抑制癌症生长的药物组合物
公开(公告)号：US06228876B1
公开(公告)日：2001-05-08
申请号：US09469389
申请日：1999-12-22
申请人： James Berger Camden
发明人： James Berger Camden
IPC分类号： A61K3141
CPC分类号： A61K31/4196
摘要： A pharmaceutical composition that inhibits the growth of tumors and cancers in mammals that comprises a material is disclosed. The particular material used is a 1H-1,2,4-triazole derivative. These compounds can also be used to treat viral infections.
摘要翻译：公开了抑制包含材料的哺乳动物中肿瘤和癌症生长的药物组合物。所用的具体材料是1H-1,2,4-三唑衍生物。这些化合物也可用于治疗病毒感染。

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