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1. 发明授权

US08864189B2 Aircraft latch comprising a hook and a handle 有权
标题翻译：包括钩和手柄的飞行器闩锁
公开(公告)号：US08864189B2
公开(公告)日：2014-10-21
申请号：US13379134
申请日：2010-06-18
申请人： Jacques Fournie , Christophe Bernus , Thony Dupas
发明人： Jacques Fournie , Christophe Bernus , Thony Dupas
IPC分类号： B65D45/34 , E05C19/14 , E05C19/12 , E05B63/06
CPC分类号： E05C19/145 , B64D29/06 , E05B63/06 , E05C19/14 , Y10S292/49 , Y10S292/60 , Y10T292/108 , Y10T292/216
摘要： An aircraft latch including a main hook; an operating lever; a safety device; a button on the operating lever and fastened to the safety device; and adjustment means attached to the safety device for adjusting the position of the safety device with respect to the main hook.
摘要翻译：包括主钩的飞机闩锁; 操作杆安全装置操作杆上的按钮并紧固到安全装置上; 以及附接到安全装置的调节装置，用于调节安全装置相对于主钩的位置。

2. 发明授权

US08436243B2 Anti-lightning system and aircraft comprising such a system 有权
标题翻译：防雷系统和包括这种系统的飞机
公开(公告)号：US08436243B2
公开(公告)日：2013-05-07
申请号：US12747463
申请日：2008-12-10
申请人： Olivier Gattus , Charles Lambert , Jacques Fournie , Jean-Christope Loche , Mathieu Giraudineau , Gautier Destombes , Gilles Mercadier , Patrick Lieven , Damien Binaud
发明人： Olivier Gattus , Charles Lambert , Jacques Fournie , Jean-Christope Loche , Mathieu Giraudineau , Gautier Destombes , Gilles Mercadier , Patrick Lieven , Damien Binaud
IPC分类号： H02G13/00
CPC分类号： H02G13/00 , B64D45/02
摘要： An anti-lightning system for a composite structure having an external surface liable to be subjected to an air flow, the aforementioned system including at least one electrically conducting strip and fasteners fastening the aforementioned strip to the structure, the aforementioned strip being electrically connected to an electrical earth for removing current. According the disclosed embodiments, the aforementioned strip has a shape intended to collaborate with a housing created at the aforementioned external surface so that the external surface of the strip lies flush with the aforementioned external surface of the structure, and the aforementioned fasteners include an upper part flush with the external surface of the strip.
摘要翻译：一种用于复合结构的防雷系统，其具有容易受到空气流动的外表面，上述系统包括至少一个导电条和将上述条紧固到结构上的紧固件，上述条电连接到用于去除电流的电气接地。根据所公开的实施例，上述条具有旨在与在前述外表面处产生的壳体协作的形状，使得带的外表面与该结构的上述外表面平齐，并且上述紧固件包括上部与条的外表面齐平。

3. 发明申请

US20100173871A1 PHOSPHORYLATED DENDRIMERS AS ANTIINFLAMMATORY DRUGS 审中-公开
标题翻译：磷酸氢钠作为抗炎药
公开(公告)号：US20100173871A1
公开(公告)日：2010-07-08
申请号：US12525416
申请日：2008-08-01
申请人： Mary Poupot , Remy Poupot , Jean-Jacques Fournie , Damien Portevin , Severine Fruchon , Jean-Luc Davignon , Cedric-Olivier Davignon , Anne-Marie Caminade , Jean-Pierre Majoral , Oliver Rolland
发明人： Mary Poupot , Remy Poupot , Jean-Jacques Fournie , Damien Portevin , Severine Fruchon , Jean-Luc Davignon , Cedric-Olivier Davignon , Anne-Marie Caminade , Jean-Pierre Majoral , Oliver Rolland
IPC分类号： A61K31/66 , A61K31/695 , A61K31/675 , A61K31/6615
CPC分类号： A61K31/80 , C07C211/14 , C07C237/10 , C07F9/26 , C07F9/3817 , C07F9/4009 , C07F9/65815 , C07F9/65817
摘要： A method for treating inflammatory diseases through an anti-inflammatory type activation of monocytes, the method includes the administration to a patient in need thereof of an effective quantity of at least one dendrimer with mono- or biphosphonic terminations.
摘要翻译：通过单核细胞的抗炎型激活治疗炎性疾病的方法，所述方法包括向有需要的患者施用有效量的至少一种具有单或双膦末端的树枝状大分子。

4. 发明授权

US06624151B1 Compounds selectively inhibiting gamma 9 delta 2 T lymphocytes 失效
标题翻译：化合物选择性抑制γ9 T 2 T淋巴细胞
公开(公告)号：US06624151B1
公开(公告)日：2003-09-23
申请号：US09958323
申请日：2001-12-20
申请人： Christian Belmant , Marc Bonneville , Marc Alix Peyrat , Jean-Jacques Fournie , Alan P. Kozikowski
发明人： Christian Belmant , Marc Bonneville , Marc Alix Peyrat , Jean-Jacques Fournie , Alan P. Kozikowski
IPC分类号： A61K3166
CPC分类号： C12N5/0636 , A61K2035/122 , C07F9/4028 , C07F9/4037 , C07F9/4075 , C07F9/65505 , C12N2501/999
摘要： The invention concerns compounds CH3—R1—(CH1)2—R2 wherein: R1 is selected among a tertiary alcohol; a 1,2-diol; a halohydrine; an apoxide; an alkene; an aldehyde or an &agr;-hydroxyaldehyde; and R2 is selected among a methylenediphosphonate; a difluoromethylenediphosphonate; or a monofluoromethylenediphosphoneate. The invention also concerns the uses of said compounds as selective inhibitors of T&ggr;9&dgr;2 lymphocytes, and their uses, in particular for therapeutic purposes.
摘要翻译：本发明涉及化合物CH3-R1（CH1）2-R2，其中：R1选自叔醇; 1,2-二醇; 卤代水过氧化物烯烃醛或α-羟基醛; 并且R2选自亚甲基二膦酸盐; 二氟亚甲基二膦酸盐; 或单氟亚甲基二膦酸酯。本发明还涉及所述化合物作为Tgamma9delta2淋巴细胞的选择性抑制剂及其用途，特别是用于治疗目的的用途。

5. 发明申请

US20100276536A1 LIGHTNING PROTECTION SYSTEM AND AIRCRAFT COMPRISING SUCH A SYSTEM 有权
标题翻译：雷击保护系统和包含这种系统的飞机
公开(公告)号：US20100276536A1
公开(公告)日：2010-11-04
申请号：US12747448
申请日：2008-12-10
申请人： Charles Lambert , Christophe Bernus , Jacques Fournie , Jean-Claude Marty
发明人： Charles Lambert , Christophe Bernus , Jacques Fournie , Jean-Claude Marty
IPC分类号： B64D45/02 , H02G13/00
CPC分类号： B64D45/02 , H02G13/00
摘要： An anti-lightning system for a composite structure having an external surface configured to be subjected to an air flow, the aforementioned system including at least one electrically conducting strip and fasteners attaching this strip to the aforementioned structure. According to the disclosed embodiments, with this structure including holes configured to accept the fastenings for the strip, at least some these fastenings comprise an attachment element that attaches the lightning to this structure. This attachment element is configured to be inserted in the hole with its upper part substantially flush with the external surface of the structure, this attachment element being in electrical contact with the electrically conducting strip. The electrically conducting strip is configured to be positioned on the opposite side of the structure to the external surface and electrically earthed.
摘要翻译：一种用于复合结构的防雷系统，其具有构造成经受空气流动的外表面，所述系统包括至少一个导电条和将该条附接到上述结构的紧固件。根据所公开的实施例，通过这种结构，包括被配置为接受条的紧固件的孔，至少一些这些紧固件包括将闪电附接到该结构的附接元件。该附接元件构造成插入孔中，其上部与结构的外表面基本齐平，该附接元件与导电条电接触。导电条被配置为位于结构的与外表面相对的一侧并且电接地。

6. 发明申请

US20090304688A1 Methods and Compositions for Increasing the Efficiency of Therapeutic Antibodies Using Gamma Delta T Cell Activators 审中-公开
标题翻译：使用Gamma Delta T细胞激活剂提高治疗性抗体效率的方法和组合物
公开(公告)号：US20090304688A1
公开(公告)日：2009-12-10
申请号：US12307047
申请日：2007-07-12
申请人： Jean-Jacques Fournie , Julie Gertner , Hélenè Sicard , Guy Laurent , Christine Bezombes
发明人： Jean-Jacques Fournie , Julie Gertner , Hélenè Sicard , Guy Laurent , Christine Bezombes
IPC分类号： A61K39/395 , A61P35/00 , A61P31/12
CPC分类号： A61K31/663 , A61K39/395 , A61K39/39558 , A61K45/06 , A61K2300/00
摘要： The present invention relates to methods and compositions for increasing the efficiency of therapeutic antibodies. More particularly, the invention relates to the use of a therapeutic antibody in combination with a γδ T cell activating compound or activated γδ T cells. thereby allowing a potentiation of γδ T cell cytotoxicity in mammalian subjects in order to enhance the efficiency of the treatment in human subjects, particularly through an increase of the depletion of targeted cells.
摘要翻译：本发明涉及用于提高治疗性抗体效率的方法和组合物。更具体地，本发明涉及治疗性抗体与Gammadelta T细胞活化化合物或活化的Gammadelta T细胞的组合的用途。从而允许在哺乳动物受试者中增强gammadelta T细胞的细胞毒性，以提高人类受试者的治疗效果，特别是通过增加靶细胞的消耗。

7. 发明申请

US20090142316A1 Use of Dendrimers to Stimulate Cell Growth 有权
标题翻译：使用树枝状大分子刺激细胞生长
公开(公告)号：US20090142316A1
公开(公告)日：2009-06-04
申请号：US11658858
申请日：2005-07-29
申请人： Jean-Pierre Majoral , Anne-Marie Jeannine Jacqueline Caminade , Jean-Jacques Fournie , Laurent Griffe , Mary Poupot-Marsan , Remy Poupot , Cedric-Olivier Turrin
发明人： Jean-Pierre Majoral , Anne-Marie Jeannine Jacqueline Caminade , Jean-Jacques Fournie , Laurent Griffe , Mary Poupot-Marsan , Remy Poupot , Cedric-Olivier Turrin
IPC分类号： A61K35/12 , C12N5/00 , C07F9/08 , C07F9/572 , C07F9/576 , A61P35/00
CPC分类号： A61K31/663 , A61K31/662 , A61K31/675 , A61K31/80 , A61K35/26 , C07F9/65815 , C07F9/65817 , C12N5/0646 , C12N2501/23 , C12N2501/999 , A61K2300/00
摘要： The present invention relates to the use of dendrimers with monophosphonic or bisphosphonic terminations in order to stimulate the growth of cell cultures or to activate cells in culture.
摘要翻译：本发明涉及具有单膦酸或双膦酸末端的树枝状大分子的用途，以刺激细胞培养物的生长或激活培养物中的细胞。

8. 发明申请

US20060287274A1 Phosphoepoxides, method for making same and uses 失效
标题翻译：磷酸氧化物，制备方法和用途
公开(公告)号：US20060287274A1
公开(公告)日：2006-12-21
申请号：US11512855
申请日：2006-08-29
申请人： Christian Belmant , Jean-Jacques Fournie , Marc Bonneville , Marie-Alix Peyrat
发明人： Christian Belmant , Jean-Jacques Fournie , Marc Bonneville , Marie-Alix Peyrat
IPC分类号： A61K48/00 , A61K38/20 , A61K38/16 , A61K31/525 , A61K31/665 , A61K31/045 , C07F9/655
CPC分类号： C07H19/10 , A61K2035/124 , C07F9/65502 , C12N5/0636 , C12N2501/23 , C12N2501/999
摘要： The invention provides compounds comprising at least one phosphoepoxide group of the formula: where R1 is selected from among —CH3 and —CH2—CH3. Cat+ is an organic or inorganic cation, n is an integer between 2 and 20, processes for the production thereof and uses thereof, in particular therapeutic uses and for activating primate Tγ9δ2 lymphocytes.
摘要翻译：本发明提供了包含至少一种下式的磷酸环氧基的化合物：其中R 1选自-CH 3 - 和-CH 2 -CH 3 >。 Cat +是有机或无机阳离子，n是2和20之间的整数，其生产方法及其用途，特别是治疗用途和激活灵长类的Tgamma9delta2淋巴细胞。

9. 发明授权

US08462481B2 Lightning protection system and aircraft comprising such a system 有权
标题翻译：包括这种系统的防雷系统和飞机
公开(公告)号：US08462481B2
公开(公告)日：2013-06-11
申请号：US12747448
申请日：2008-12-10
申请人： Charles Lambert , Christophe Bernus , Jacques Fournie , Jean-Claude Marty
发明人： Charles Lambert , Christophe Bernus , Jacques Fournie , Jean-Claude Marty
IPC分类号： H02H1/04
CPC分类号： B64D45/02 , H02G13/00
摘要： An anti-lightning system for a composite structure having an external surface configured to be subjected to an air flow, the aforementioned system including at least one electrically conducting strip and fasteners attaching this strip to the aforementioned structure. According to the disclosed embodiments, with this structure including holes configured to accept the fastenings for the strip, at least some these fastenings comprise an attachment element that attaches the lightning to this structure. This attachment element is configured to be inserted in the hole with its upper part substantially flush with the external surface of the structure, this attachment element being in electrical contact with the electrically conducting strip. The electrically conducting strip is configured to be positioned on the opposite side of the structure to the external surface and electrically earthed.
摘要翻译：一种用于复合结构的防雷系统，其具有构造成经受空气流动的外表面，所述系统包括至少一个导电条和将该条附接到上述结构的紧固件。根据所公开的实施例，通过这种结构，包括被配置为接受条的紧固件的孔，至少一些这些紧固件包括将闪电附接到该结构的附接元件。该附接元件构造成插入孔中，其上部与结构的外表面基本齐平，该附接元件与导电条电接触。导电条被配置为位于结构的与外表面相对的一侧并且电接地。

10. 发明授权

US07625879B2 Phosphohalohydrins, process for the production thereof and use thereof 失效
标题翻译：磷代氢化醇，其制备方法和用途
公开(公告)号：US07625879B2
公开(公告)日：2009-12-01
申请号：US11512688
申请日：2006-08-30
申请人： Christian Belmant , Jean-Jacques Fournie , Marc Bonneville , Marie-Alix Peyrat
发明人： Christian Belmant , Jean-Jacques Fournie , Marc Bonneville , Marie-Alix Peyrat
IPC分类号： A61K31/66 , A01N57/00 , G01N33/00 , C12N5/06 , C12N5/16 , A01N65/00 , C07D301/36 , C07D303/02 , C07C321/00 , C07C323/00 , C07C381/00
CPC分类号： C07H19/10 , A61K31/66 , A61K39/00 , A61K45/06 , A61K2035/124 , A61K2039/55511 , C07F9/098 , C12N5/0636 , C12N2501/23 , C12N2501/999 , Y02A50/412
摘要： The invention provides compounds comprising at least one phosphohalohydrin group of the formula: where X is a halogen selected from among I, Br, Cl, R1 is selected from among —CH3 and —CH2—CH3, Cat+ is an organic or inorganic cation, and n is an integer between 2 and 20, processes for the production thereof and uses thereof, in particular therapeutic uses and for activating primate Tγ9δ2 lymphocytes.
摘要翻译：本发明提供了包含至少一种下式的磷酸卤代醇基团的化合物：其中X是选自I，Br，Cl中的卤素，R 1选自-CH 3和-CH 2 -CH 3，Cat +是有机或无机阳离子，和 n是2至20之间的整数，其制备方法及其用途，特别是治疗用途和用于激活灵长类的Tgamma9delta2淋巴细胞。

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