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1. 发明申请

WO2009061017A1 BIO LAB-ON-A-CHIP AND METHOD OF FABRICATING AND OPERATING THE SAME 审中-公开
公开(公告)号：WO2009061017A1
公开(公告)日：2009-05-14
申请号：PCT/KR2007/005655
申请日：2007-11-09
申请人： ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE , LEE, Dae Sik , PARK, Rae Man , MAENG, Sung Lyul , JUNG, Moon Youn , PARK, Seon Hee
发明人： LEE, Dae Sik , PARK, Rae Man , MAENG, Sung Lyul , JUNG, Moon Youn , PARK, Seon Hee
IPC分类号： G01N33/48
CPC分类号： G01N33/54366 , B01L3/502707 , B01L3/50273 , B01L2200/0673 , B01L2300/0636 , B01L2300/0645 , B01L2300/0816 , B01L2300/089 , B01L2300/161 , B01L2400/0436 , B01L2400/0496 , G01N33/5438
摘要： Disclosed is a bio lab-on-a-chip. The bio lab-on-a-chip is provided on a piez)electric thin film on a substrate, and includes a sensing unit to sense a bio signal and a fluidic control unit which controls a transfer of a microfluid adjacent to the sensing unit. Provided is also a method of fabricating the bio lab-on-a-chip. The method includes the steps of forming a piez)electric thin film, forming a sensing unit to sense a bio signal of a microfluid on the piez)electric thin film, and forming a fluidic control unit located adjacent to the sensing unit.
摘要翻译：公开了一种生物实验室芯片。芯片上的生物实验室被提供在基板上的压电薄膜上，并且包括用于感测生物信号的感测单元和控制与感测单元相邻的微流体传输的流体控制单元。还提供了一种制造生物芯片实验室的方法。该方法包括形成压电薄膜的步骤，形成感测单元以感测压电薄膜上的微流体的生物信号，以及形成位于感测单元附近的流体控制单元。

2. 发明申请

WO2009075437A1 SEMI-QUANTITATIVE IMMUNOLOGICAL DETECTION DEVICE WITH DIFFERENTIAL ANTIBODIES OR SUBSTRATES 审中-公开
标题翻译：具有差异抗体或底物的半定量免疫检测装置
公开(公告)号：WO2009075437A1
公开(公告)日：2009-06-18
申请号：PCT/KR2008/003585
申请日：2008-06-24
申请人： ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE , CHOI, Yo Han , JUNG, Moon Youn , PARK, Seon Hee
发明人： CHOI, Yo Han , JUNG, Moon Youn , PARK, Seon Hee
IPC分类号： G01N33/53 , G01N35/00
CPC分类号： G01N33/54386 , B01L3/5027 , B01L2300/0636 , B01L2300/0681 , B01L2300/0816 , B01L2300/0864 , B01L2400/0406 , B01L2400/0487
摘要： A semi-quantitative immunological detection device with differential antibodies and substrates is provided. The semi-quantitative immunological detection device with differential antibodies, includes: a sample injecting portion through which a sample is injected; and a reaction portion where a plurality of reacting materials reacting with an MUT (material under test) contained in the sample with different sensitivities to generate marker materials are disposed in the same space. Accordingly, a diagnosis result can be visually identified with user's eyes, and the diagnosis result similar to that of a quantitative assay apparatus can be provided.
摘要翻译：提供了具有差异抗体和底物的半定量免疫检测装置。具有差异抗体的半定量免疫检测装置包括：注射样品的样品注入部分; 和反应部分，其中多个反应材料与MUT（试验中的材料）反应，具有不同的灵敏度产生标记材料的样品被放置在相同的空间中。因此，可以用用户的眼睛可视地识别诊断结果，并且可以提供类似于定量测定装置的诊断结果。

3. 发明申请

WO2009072715A1 MICRO-SCALED ANIMAL CELL INCUBATOR AND PRODUCTION METHOD THEREOF 审中-公开
标题翻译：微量级动物细胞培养物及其生产方法
公开(公告)号：WO2009072715A1
公开(公告)日：2009-06-11
申请号：PCT/KR2008/003741
申请日：2008-06-27
申请人： ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE , CHOI, Yo Han , CHUNG, Kwang Hyo , LEE, Dae Sik , KIM, Sang Hee , JEONG, Min Suk , JUN, Chi Hoon , JUNG, Moon Youn , PARK, Seon Hee
发明人： CHOI, Yo Han , CHUNG, Kwang Hyo , LEE, Dae Sik , KIM, Sang Hee , JEONG, Min Suk , JUN, Chi Hoon , JUNG, Moon Youn , PARK, Seon Hee
IPC分类号： C12M3/00
CPC分类号： C12M23/20 , B01L3/5027 , B01L7/00 , C12M23/16 , C12M41/12 , Y10T29/49124
摘要： There is provided a cell culture technology for culturing an animal cell in a separate microstructure. The micro-scaled animal cell incubator includes a lower glass substrate having fine hot wires processed with a metal and formed in an upper surface thereof; a first PDMS film attached onto the lower glass substrate to form two or more liquid and solid storage spaces in a position corresponding to the fine hot wires of the lower glass substrate and gas flow channels coupled respectively to the liquid and solid storage spaces to allow generated gases to flow therethrough; a gas-permeable PDMS thin film attached onto the gas flow channels of the PDMS film to pass the generated gases therethrough; a second PDMS film attached onto the PDMS thin film and having a culture medium storage space for storing a culture medium; and an upper glass substrate attached onto the second PDMS film and having fine hot wires formed in a lower surface thereof, the fine hot wires being covered by the PDMS film. The micro-scaled animal cell incubator may be useful to control a temperature of a culture medium to a suitable temperature level, as well as to self-supply gases required for the animal cell culture in a microstructure.
摘要翻译：提供了用于在单独的微结构中培养动物细胞的细胞培养技术。微型动物细胞培养箱包括具有用金属加工并形成在其上表面的细微热丝的下玻璃基板; 附着在下玻璃基板上的第一PDMS膜，以形成两个或更多个液体和固体存储空间，该液体和固体储存空间位于对应于分别与液体和固体储存空间相连的下部玻璃基板和气体流动通道的细微热线的位置，以允许产生气体流过其中; 透气的PDMS薄膜，附着在PDMS薄膜的气流通道上，以使产生的气体通过; 附着在PDMS薄膜上并具有用于储存培养基的培养基存储空间的第二PDMS膜; 以及附着在第二PDMS膜上并具有形成在其下表面上的精细热丝的上玻璃基板，细的热丝被PDMS膜覆盖。微量级动物细胞培养箱可用于将培养基的温度控制到合适的温度水平，以及自动供应在微结构中动物细胞培养所需的气体。

4. 发明申请

WO2009078511A1 FLUORESCENCE MICROSCOPE USING SURFACE PLASMON RESONANCE 审中-公开
标题翻译：使用表面等离子体共振的荧光显微镜
公开(公告)号：WO2009078511A1
公开(公告)日：2009-06-25
申请号：PCT/KR2008/003114
申请日：2008-06-04
申请人： ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE , PYO, Hyeon Bong , JUNG, Moon Youn , PARK, Seon Hee
发明人： PYO, Hyeon Bong , JUNG, Moon Youn , PARK, Seon Hee
IPC分类号： G02B21/06
CPC分类号： G02B21/16 , G01N21/648
摘要： A fluorescence microscope using a Surface plasmon resonance (SPR) includes a monochromatic light provision unit, an SPR sensor, and a first light detector. The monochromatic light provision unit provides a monochromatic light consistent with an absorption wavelength of a specific fluorophore attached to a sample. The SPR sensor excites surface plasmons to amplify a fluorescence signal of the specific fluorophore. The first light detector detects the fluorescence signal to enable monitoring of a fluorescence intensity of the sample.
摘要翻译：使用表面等离子体共振（SPR）的荧光显微镜包括单色光提供单元，SPR传感器和第一光检测器。单色光提供单元提供与附接到样品的特定荧光团的吸收波长一致的单色光。 SPR传感器激发表面等离子体激元以扩增特定荧光团的荧光信号。第一光检测器检测荧光信号以便能够监测样品的荧光强度。

5. 发明申请

WO2009078510A1 DISPOSABLE SURFACE PLASMON RESONANCE BIOSENSOR AND SYSTEM USING THE SAME 审中-公开
标题翻译：可替换的表面等离子体共振生物传感器和使用它的系统
公开(公告)号：WO2009078510A1
公开(公告)日：2009-06-25
申请号：PCT/KR2008/003113
申请日：2008-06-04
申请人： ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE , PYO, Hyeon Bong , JUNG, Moon Youn , PARK, Seon Hee
发明人： PYO, Hyeon Bong , JUNG, Moon Youn , PARK, Seon Hee
IPC分类号： G01N33/48 , G01N33/20
CPC分类号： G01N21/553 , G01N33/54373
摘要： A Surface Plasmon Resonance (SPR) biosensor and system using the same are provided. The biosensor includes a sensor substrate and a thin metal film. The sensor substrate is configured to have a prism and a flat type transparent dielectric substrate formed of the same material in a body. The thin metal film is formed in a position, which faces the prism, on an opposite surface to a surface on which the prism of the sensor substrate is formed and generates SPR by light impinged on the prism.
摘要翻译：提供表面等离子体共振（SPR）生物传感器和使用其的系统。生物传感器包括传感器基板和薄金属膜。传感器基板被配置为具有由主体中的相同材料形成的棱镜和平面型透明电介质基板。薄金属膜形成在与形成有传感器基板的棱镜的表面相反的表面上的与棱镜相对的位置，并通过入射在棱镜上的光产生SPR。

6. 发明申请

WO2012046977A3 TARGET STRUCTURE USED IN CHARGED PARTICLE BEAM GENERATION, A PRODUCTION METHOD THEREFOR, AND A MEDICAL DEVICE USING THE SAME 审中-公开
标题翻译：充电粒子束生成中使用的目标结构，其生产方法和使用其的医疗装置
公开(公告)号：WO2012046977A3
公开(公告)日：2012-06-21
申请号：PCT/KR2011007258
申请日：2011-09-30
申请人： KOREA ELECTRONICS TELECOMM , CHO SEONG-MOK , JUNG MOON YOUN , KIM SEUNGHWAN
发明人： CHO SEONG-MOK , JUNG MOON YOUN , KIM SEUNGHWAN
IPC分类号： A61N5/10 , A61B18/00 , A61N5/067
CPC分类号： A61N5/1077 , A61B18/20 , A61N2005/1088
摘要： Provided are a target structure used in charged particle beam generation, a production method therefor, and a medical device using the same. The target structure comprises: a target layer; and a support having through holes that are used as passageways for the progress of a laser beam or a charged particle beam.
摘要翻译：提供了用于带电粒子束产生的目标结构及其制造方法以及使用该目标结构的医疗装置。目标结构包括：目标层; 以及具有用于激光束或带电粒子束的进行通道的通孔的支撑件。

7. 发明申请

WO2009075414A1 PS-SPCL SEARCHING APPARATUS AND METHOD USING SURFACE PLASMON RESONANCE 审中-公开
标题翻译： PS-SPCL搜索设备和使用表面等离子体共振的方法
公开(公告)号：WO2009075414A1
公开(公告)日：2009-06-18
申请号：PCT/KR2008/002162
申请日：2008-04-17
申请人： ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE , CHOI, Yo Han , JUNG, Moon Youn , PARK, Seon Hee
发明人： CHOI, Yo Han , JUNG, Moon Youn , PARK, Seon Hee
IPC分类号： G01N33/48 , G01N21/00
CPC分类号： G01N33/54373 , C40B30/00 , G01N21/553
摘要： A Positional Scanning - Synthetic Peptide Combinatorial Library (PS-SPC) searching apparatus and method using Surface Plasmon Resonance (SPR) are provided. The method includes spotting and fixing each of a plurality of peptide pools to a top of one thin metal film, inputting specific materials to the top of the thin metal film, applying a TM-mode light to a bottom of the thin metal film and exciting SPR for the thin metal film, and detecting a TM mode reflected light reflected from the thin metal film and displaying the detected light as a two-dimensional image.
摘要翻译：提供了使用表面等离子体共振（SPR）的位置扫描 - 合成肽组合库（PS-SPC）搜索装置和方法。该方法包括将多个肽池中的每一个点样并固定到一个薄金属膜的顶部，将特定材料输入到金属薄膜的顶部，向薄金属膜的底部施加TM模式的光，并激发 SPR，并且检测从薄金属膜反射的TM模式反射光，并将检测到的光显示为二维图像。

8. 发明申请

WO2009051432A2 LAB-ON-A-CHIP AND METHOD OF DRIVING THE SAME 审中-公开
标题翻译：片上实验室及其驱动方法
公开(公告)号：WO2009051432A2
公开(公告)日：2009-04-23
申请号：PCT/KR2008/006135
申请日：2008-10-17
申请人： ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE , JUNG, Moon-Youn , SHIN, Dong-Ho , KIM, Young-Jun , JEONG, Minsuk , KIM, Sanghee , KIM, Hye-Yoon , PARK, Seon-Hee
发明人： JUNG, Moon-Youn , SHIN, Dong-Ho , KIM, Young-Jun , JEONG, Minsuk , KIM, Sanghee , KIM, Hye-Yoon , PARK, Seon-Hee
IPC分类号： G01N33/49
CPC分类号： G01N33/49
摘要： Provided is a lab-on-a-chip. The lab-on-a-chip includes a first region where a lower substrate and an upper substrate are bonded to each other, a second region where the lower and upper substrates are not bonded, and a gap adjusting member disposed at an end of the second region that is opposite to a boundary between the first and second regions, the gap adjusting member being configured to adjust a gap between the first and second substrates to control a capillary force.
摘要翻译：
提供芯片实验室。芯片实验室包括下基板和上基板彼此接合的第一区域，未接合下基板和上基板的第二区域以及设置在第一区域的端部处的间隙调节构件第二区域与第一和第二区域之间的边界相对，所述间隙调节构件被配置为调节第一和第二基板之间的间隙以控制毛细作用力。

9. 发明申请

WO2009051432A3 LAB-ON-A-CHIP AND METHOD OF DRIVING THE SAME 审中-公开
标题翻译： LAB-ON-A-CHIP及其驱动方法
公开(公告)号：WO2009051432A3
公开(公告)日：2009-06-04
申请号：PCT/KR2008006135
申请日：2008-10-17
申请人： KOREA ELECTRONICS TELECOMM , JUNG MOON-YOUN , SHIN DONG-HO , KIM YOUNG-JUN , JEONG MINSUK , KIM SANGHEE , KIM HYE-YOON , PARK SEON-HEE
发明人： JUNG MOON-YOUN , SHIN DONG-HO , KIM YOUNG-JUN , JEONG MINSUK , KIM SANGHEE , KIM HYE-YOON , PARK SEON-HEE
IPC分类号： G01N33/49
CPC分类号： G01N33/49
摘要： Provided is a lab-on-a-chip. The lab-on-a-chip includes a first region where a lower substrate and an upper substrate are bonded to each other, a second region where the lower and upper substrates are not bonded, and a gap adjusting member disposed at an end of the second region that is opposite to a boundary between the first and second regions, the gap adjusting member being configured to adjust a gap between the first and second substrates to control a capillary force.
摘要翻译：提供了一个芯片实验室。芯片实验室包括下基板和上基板彼此接合的第一区域，下基板和上基板未接合的第二区域，以及设置在该基板的末端的间隙调节构件所述第二区域与所述第一和第二区域之间的边界相对，所述间隙调节构件被配置为调节所述第一和第二基板之间的间隙以控制毛细管力。

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