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1. 发明专利

CA53692A SPRING BEDSTEAD 未知
公开(公告)号：CA53692A
公开(公告)日：1896-10-07
申请号：CA53692D
申请日：1896-09-16
申请人： JONES WILLIAM M
发明人： JONES WILLIAM M

2. 发明申请

WO2005048443A3 BRUSHLESS REPULSION MOTOR SPEED CONTROL SYSTEM 审中-公开
公开(公告)号：WO2005048443A3
公开(公告)日：2005-05-26
申请号：PCT/US2004/036280
申请日：2004-11-01
申请人： DYNAMOTORS, INC. , JONES, William, M.
发明人： JONES, William, M.
IPC分类号： H02P7/638
摘要： A system for controlling the speed of a brushless repulsion motor having a series of switches mounted on a rotating armature for shorting circumferentially spaced armature coils comprising first stationary signaling means and a plurality of rotating detectors for activating said switches; second stationary signaling means for speed control; a plurality of markers on the rotating armature; a speed detector for detecting the speed of the rotating markers and generating a speed feedback signal; means for generating a speed command signal; an error calculator for comparing the speed feedback and speed command signals and generating an error signal; and a controller for controlling the signaling means based on the error signal.

3. 发明申请

WO2005048443A2 BRUSHLESS REPULSION MOTOR SPEED CONTROL SYSTEM 审中-公开
标题翻译：无刷马达速度控制系统
公开(公告)号：WO2005048443A2
公开(公告)日：2005-05-26
申请号：PCT/US2004036280
申请日：2004-11-01
申请人： DYNAMOTORS INC , JONES WILLIAM M
发明人： JONES WILLIAM M
IPC分类号： H02P25/10 , H02P
CPC分类号： H02P25/102
摘要： A system for controlling the speed of a brushless repulsion motor having a series of switches mounted on a rotating armature for shorting circumferentially spaced armature coils comprising first stationary signaling means and a plurality of rotating detectors for activating said switches; second stationary signaling means for speed control; a plurality of markers on the rotating armature; a speed detector for detecting the speed of the rotating markers and generating a speed feedback signal; means for generating a speed command signal; an error calculator for comparing the speed feedback and speed command signals and generating an error signal; and a controller for controlling the signaling means based on the error signal.
摘要翻译：一种用于控制无刷排斥电动机的速度的系统，其具有安装在旋转电枢上的一系列开关，用于短路周向间隔的电枢线圈，该电枢线圈包括第一固定信号装置和用于启动所述开关的多个旋转检测器; 用于速度控制的第二固定信号装置; 旋转电枢上的多个标记; 速度检测器，用于检测旋转标记的速度并产生速度反馈信号; 用于产生速度指令信号的装置; 误差计算器，用于比较速度反馈和速度指令信号并产生误差信号; 以及控制器，用于基于所述误差信号来控制所述信令装置。

4. 发明专利

CA18558A CHURN 未知
公开(公告)号：CA18558A
公开(公告)日：1884-01-25
申请号：CA18558D
申请人： JONES WILLIAM M , POMEROY DANIEL K
发明人： POMEROY DANIEL K

5. 发明申请

WO2010068452A1 HETEROARYL-SUBSTITUTED UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE 审中-公开
标题翻译：脂肪酸酰胺水解物的替代尿素调节剂
公开(公告)号：WO2010068452A1
公开(公告)日：2010-06-17
申请号：PCT/US2009/065752
申请日：2009-11-24
申请人： JANSSEN PHARMACEUTICA NV , BREITENBUCHER, J., Guy , KEITH, John, M. , TICHENOR, Mark, S. , CHAMBERS, Alison, L. , JONES, William, M. , HAWRYLUK, Natalie, A. , TIMMONS, Amy, K. , MERIT, Jeffrey, E. , SEIERSTAD, Mark, J.
发明人： BREITENBUCHER, J., Guy , KEITH, John, M. , TICHENOR, Mark, S. , CHAMBERS, Alison, L. , JONES, William, M. , HAWRYLUK, Natalie, A. , TIMMONS, Amy, K. , MERIT, Jeffrey, E. , SEIERSTAD, Mark, J.
IPC分类号： C07D401/12 , C07D471/04 , A61K31/47 , A61P29/00
CPC分类号： C07D498/04 , A61K31/437 , A61K31/454 , A61K31/4545 , A61K31/4709 , A61K31/5025 , A61K31/506 , A61K45/06 , C07D401/12 , C07D401/14 , C07D405/14 , C07D413/12 , C07D471/04 , C07D487/04
摘要： Certain heteroaryl-substituted piperidinyl and piperazinyl urea compounds are described, which are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity, such as anxiety, pain, inflammation, sleep disorders, eating disorders, insulin resistance, diabetes, osteoporosis, and movement disorders (e.g., multiple sclerosis).
摘要翻译：描述了某些杂芳基取代的哌啶基和哌嗪基脲化合物，其可用作FAAH抑制剂。这些化合物可用于治疗由脂肪酸酰胺水解酶（FAAH）活性介导的疾病状态，病症和病症的药物组合物和方法，例如焦虑症，疼痛，炎症，睡眠障碍，进食障碍，胰岛素抵抗，糖尿病，骨质疏松症和运动障碍（例如，多发性硬化症）。

6. 发明申请

WO2008153752A2 HETEROARYL-SUBSTITUTED UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE 审中-公开
标题翻译：脂肪酸酰胺水解物的替代尿素调节剂
公开(公告)号：WO2008153752A2
公开(公告)日：2008-12-18
申请号：PCT/US2008006607
申请日：2008-05-23
申请人： JANSSEN PHARMACEUTICA NV , APODACA RICHARD , BREITENBUCHER J GUY , HAWRYLUK NATALIE A , JONES WILLIAM M , KEITH JOHN M , MERIT JEFFREY E , TICHENOR MARK S , TIMMONS AMY K
发明人： APODACA RICHARD , BREITENBUCHER J GUY , HAWRYLUK NATALIE A , JONES WILLIAM M , KEITH JOHN M , MERIT JEFFREY E , TICHENOR MARK S , TIMMONS AMY K
IPC分类号： C07D401/00 , A61K31/445 , A61K31/496 , A61K31/501 , A61P1/00 , C07D403/00 , C07D403/14
CPC分类号： C07D231/40 , C07D237/20 , C07D241/20 , C07D257/06 , C07D261/14 , C07D261/20 , C07D271/12 , C07D285/14 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04
摘要： Certain heteroaryl-substituted piperidinyl and piperazinyl urea compounds are described, which are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity, such as anxiety, pain, inflammation, sleep disorders, eating disorders, insulin resistance, diabetes, osteoporosis, and movement disorders (e.g., multiple sclerosis).
摘要翻译：描述了某些杂芳基取代的哌啶基和哌嗪基脲化合物，其可用作FAAH抑制剂。这些化合物可用于治疗由脂肪酸酰胺水解酶（FAAH）活性介导的疾病状态，病症和病症的药物组合物和方法，例如焦虑症，疼痛，炎症，睡眠障碍，进食障碍，胰岛素抵抗，糖尿病，骨质疏松症和运动障碍（例如，多发性硬化症）。

7. 发明申请

WO2022104348A1 SMALL MOLECULE INHIBITORS OF NF-KB INDUCING KINASE 审中-公开
公开(公告)号：WO2022104348A1
公开(公告)日：2022-05-19
申请号：PCT/US2021/072343
申请日：2021-11-11
申请人： JANSSEN PHARMACEUTICA NV , JONES, William M.
发明人： LEBSACK, Alec D. , WOLIN, Ronald L. , ROVIRA, Alexander R.
IPC分类号： C07D471/04 , C07D487/04 , C07D519/00 , C07D417/14 , A61K31/437 , A61K31/519 , A61P35/00 , A61P29/00 , A61P37/00 , A61P3/00
摘要： This invention relates to compounds of Formula I that inhibit NIK and pharmaceutical compositions comprising such compounds and methods of using the same. These compounds and pharmaceutical compositions are useful for preventing or treating diseases such as cancer (such as B-cell malignancies including leukemias, lymphomas and myeloma), inflammatory disorders, autoimmune disorders, immunodermatologic disorders such as palmoplantar pustulosis and hidradenitis suppurativa, and metabolic disorders such as obesity and diabetes.

8. 发明申请

WO2011022348A1 ETHYLENE DIAMINE MODULATORS OF FATTY ACID AMIDE HYDROLASE 审中-公开
标题翻译：脂肪酸酰胺水解酶的乙烯二胺调节剂
公开(公告)号：WO2011022348A1
公开(公告)日：2011-02-24
申请号：PCT/US2010/045683
申请日：2010-08-17
申请人： JANSSEN PHARMACEUTICA NV , HAWRYLUK, Natalie, A. , BREITENBUCHER, J., Guy , JONES, William, M. , CHAMBERS, Alison, L. , KEITH, John, M. , SEIERSTAD, Mark
发明人： HAWRYLUK, Natalie, A. , BREITENBUCHER, J., Guy , JONES, William, M. , CHAMBERS, Alison, L. , KEITH, John, M. , SEIERSTAD, Mark
IPC分类号： C07D239/42 , C07D401/04 , C07D403/12 , C07D405/04 , C07D405/12 , C07D409/04 , C07D409/12 , C07D413/04 , C07D413/12 , C07D417/12 , A61K31/506 , A61P25/00 , A61P29/00
CPC分类号： C07D239/42 , C07D401/04 , C07D403/12 , C07D405/04 , C07D405/12 , C07D409/04 , C07D409/12 , C07D413/04 , C07D413/12 , C07D417/12
摘要： Certain ethylene diamine compounds of Formula (I) are described, which are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity, such as anxiety, pain, inflammation, sleep disorders, eating disorders, energy metabolism disorders, and movement disorders (e.g., multiple sclerosis). Methods of synthesizing such compounds are also disclosed.
摘要翻译：描述了某些式（I）的乙二胺化合物，其可用作FAAH抑制剂。这些化合物可用于治疗由脂肪酰胺水解酶（FAAH）活性介导的疾病状态，病症和病症的药物组合物和方法，例如焦虑症，疼痛，炎症，睡眠障碍，进食障碍，能量代谢紊乱，和运动障碍（例如多发性硬化）。还公开了合成这些化合物的方法。

9. 发明申请

WO2010068453A1 HETEROARYL-SUBSTITUTED UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE 审中-公开
标题翻译：脂肪酸酰胺水解酶的杂芳基取代尿素调节剂
公开(公告)号：WO2010068453A1
公开(公告)日：2010-06-17
申请号：PCT/US2009/065757
申请日：2009-11-24
申请人： JANSSEN PHARMACEUTICA NV , BREITENBUCHER, J., Guy , KEITH, John, M. , TICHENOR, Mark, S. , CHAMBERS, Alison, L. , JONES, William, M. , HAWRYLUK, Natalie, A. , TIMMONS, Amy, K. , MERIT, Jeffrey, E. , SEIERSTAD, Mark, J.
发明人： BREITENBUCHER, J., Guy , KEITH, John, M. , TICHENOR, Mark, S. , CHAMBERS, Alison, L. , JONES, William, M. , HAWRYLUK, Natalie, A. , TIMMONS, Amy, K. , MERIT, Jeffrey, E. , SEIERSTAD, Mark, J.
IPC分类号： C07D403/12 , C07D413/12 , C07D413/14 , C07D471/04 , C07D471/12 , C07D487/04 , C07D498/04 , A61K31/519 , A61P29/00
CPC分类号： C07D498/04 , C07D231/56 , C07D295/195 , C07D403/12 , C07D413/12 , C07D413/14 , C07D471/04 , C07D471/12 , C07D487/04
摘要： Certain heteroaryl-substituted piperidinyl and piperazinyl urea compounds are described, which are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity, such as anxiety, pain, inflammation, sleep disorders, eating disorders, insulin resistance, diabetes, osteoporosis, and movement disorders (e.g., multiple sclerosis).
摘要翻译：描述了某些杂芳基取代的哌啶基和哌嗪基脲化合物，其可用作FAAH抑制剂。此类化合物可用于治疗由脂肪酸酰胺水解酶（FAAH）活性（例如焦虑，疼痛，炎症，睡眠障碍，进食障碍，胰岛素抵抗，糖尿病）介导的疾病状态，病症和病症的药物组合物和方法，骨质疏松症和运动障碍（例如多发性硬化）。

10. 发明申请

WO2010141817A1 HETEROARYL-SUBSTITUTED SPIROCYCLIC DIAMINE UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE 审中-公开
标题翻译：脂肪酸酰胺水解酶的替代螺旋线性尿素调节剂
公开(公告)号：WO2010141817A1
公开(公告)日：2010-12-09
申请号：PCT/US2010/037402
申请日：2010-06-04
申请人： JANSSEN PHARMACEUTICA NV , BREITENBUCHER, Guy, J. , KEITH, John, M. , JONES, William, M.
发明人： BREITENBUCHER, Guy, J. , KEITH, John, M. , JONES, William, M.
IPC分类号： C07D471/10 , C07D487/10 , A61K31/397 , A61K31/407 , A61K31/4747 , A61P19/08 , A61P25/22 , A61P25/24 , A61P29/00
CPC分类号： C07D471/10 , C07D487/10
摘要： Certain heteroaryl-substituted spirocyclic diamine urea compounds are described, which are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity, such as anxiety, pain, inflammation, sleep disorders, eating disorders, energy metabolism disorders, and movement disorders (e.g., multiple sclerosis).
摘要翻译：描述了某些杂芳基取代的螺环二胺脲化合物，其可用作FAAH抑制剂。这些化合物可用于治疗由脂肪酰胺水解酶（FAAH）活性介导的疾病状态，病症和病症的药物组合物和方法，例如焦虑症，疼痛，炎症，睡眠障碍，进食障碍，能量代谢紊乱，和运动障碍（例如多发性硬化）。

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