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1. 发明申请

WO2005109707A2 GATEWAY APPLICATION TO SUPPORT USE OF A SINGLE INTERNET ADDRESS DOMAIN FOR ROUTING MESSAGES TO MULTIPLE MULTIMEDIA MESSAGE SERVICE CENTERS 审中-公开
标题翻译：网关应用程序支持使用单个互联网地址将消息传送到多个多媒体消息服务中心
公开(公告)号：WO2005109707A2
公开(公告)日：2005-11-17
申请号：PCT/US2005/015667
申请日：2005-05-06
申请人： TELECOMMUNICATION SYSTEMS, INC. , JOHNSON, Carl, S., Jr. , DEWEY, Mike , BHADANGE, Nikhil
发明人： JOHNSON, Carl, S., Jr. , DEWEY, Mike , BHADANGE, Nikhil
IPC分类号： H04J3/24
CPC分类号： H04W4/12 , H04W88/184 , H04W92/02 , H04W92/06 , H04W92/24
摘要： Wireless carrier networks can utilize multiple MMSCs all accessed by a message sender with a message addressed to a single Internet domain, providing a single point of entry for messages into the network of MMSCs and maintaining routing information sufficient to route messages to all subscribers via the MMSC.
摘要翻译：无线运营商网络可以利用所有由消息发送者访问的多个MMSC，其中消息寻址到单个因特网域，为MMSC的网络中的消息提供单个入口点，并维持路由信息足以通过MMSC将消息路由到所有订户。

2. 发明申请

WO9966324A2 A BIOLUMINESCENCE RESONANCE ENERGY TRANSFER (BRET) SYSTEM AND ITS USE 审中-公开
标题翻译：生物共振能量转移（BRET）系统及其使用
公开(公告)号：WO9966324A2
公开(公告)日：1999-12-23
申请号：PCT/CA9900561
申请日：1999-06-16
申请人： JOLY ERIK , JOHNSON CARL H , PISTON DAVID W
发明人： JOLY ERIK , JOHNSON CARL H , PISTON DAVID W
IPC分类号： C07K14/195 , C07K14/435 , C12N9/02 , C12N15/62 , G01N33/542 , G01N33/53
CPC分类号： C12N9/0069 , C07K14/195 , C07K14/43595 , C07K2319/09 , C07K2319/72 , C07K2319/80 , C07K2319/90 , C12N15/62 , G01N33/542 , G01N2333/43595
摘要： This invention provides bioluminescence resonance energy transfer (BRET) system that comprises four parts: 1) a bioluminescent protein that has luciferase activity; 2) an acceptor fluorophore that can accept the energy from the bioluminescent protein when they are associated, in the presence of the appropriate substrate; 3) a modulator that influences the proximity or the orientation of the bioluminescent protein and the fluorophore, and 4) an appropriate substrate to activate the luciferase activity of the bioluminescent protein. The components of this system interact to influence the spatial relationship between the bioluminescent protein and the fluorophore, that is demonstrated by the light emission from the system. The modulator can be a single entity, covalently attached to both the bioluminescent protein and the fluorophore, it can be two separate entities, each linked covalently to either the bioluminescent protein or the fluorophore, or an alternative configuration that falls within the scope of the invention. Thissystem can be used in both in vivo or in vitro assays to detect molecular changes in a wide variety of applications, and is amenable to automation. In particular, it is useful for assaying protein interactions, enzyme activities and the concentration of analytes or signaling molecules in cells or in solution.
摘要翻译：本发明提供生物发光共振能量转移（BRET）系统，其包括四个部分：1）具有荧光素酶活性的生物发光蛋白; 2）受体荧光团，当在适当的底物存在下，可接受来自生物发光蛋白的能量; 3）影响生物发光蛋白和荧光团的接近度或取向的调节剂，以及4）活化生物发光蛋白的荧光素酶活性的合适底物。该系统的组分相互影响生物发光蛋白和荧光团之间的空间关系，这是由系统的光发射所证明的。调节剂可以是共价连接生物发光蛋白质和荧光团的单个实体，它可以是两个分开的实体，每个实体共价连接到生物发光蛋白质或荧光团，或属于本发明范围内的替代配置。该系统可用于体内或体外测定以检测各种应用中的分子变化，并且适于自动化。特别地，它可用于测定细胞或溶液中的蛋白质相互作用，酶活性和分析物或信号分子的浓度。

3. 发明申请

WO1997046548A1 DIHYDROBENZOPYRAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS 审中-公开
标题翻译：二氢苯并噻吩和相关化合物作为抗炎药物有用
公开(公告)号：WO1997046548A1
公开(公告)日：1997-12-11
申请号：PCT/US1997009945
申请日：1997-06-06
申请人： THE PROCTER & GAMBLE COMPANY , JANUSZ, John, Michael , JOHNSON, Carl, Randolph , SENANAYAKE, Chandrawansha, Bandara, W.
发明人： THE PROCTER & GAMBLE COMPANY
IPC分类号： C07D311/58
CPC分类号： C07D335/06 , C07D311/58
摘要： A compound having structure (I) wherein (a) X is selected from the group consisting of O, S, SO, or SO2; (b) each Y is independently hydrogen or straight, branched or cyclic alkanyl having from 1 to about 4 carbon atoms, or the two Y's are bonded to form an alkanyl ring having from 3 to about 7 carbon atoms; (c) Z is branched or cyclic alkyl having from 3 to about 10 atoms other than hydrogen; (d) W is O or S; and (e) R is straight, branched or cyclic alkyl or aryl, saturated or mono- or di-unsaturated with double or triple bonds, R having from 1 to about 15 atoms other than hydrogen; pharmaceutical compositions comprising such compounds, and methods of treating inflammation or pain using such compounds.
摘要翻译：具有结构（I）的化合物，其中（a）X选自O，S，SO或SO 2; （b）每个Y独立地为氢或具有1至约4个碳原子的直链，支链或环状烷基，或两个Y键合以形成具有3至约7个碳原子的烷基环; （c）Z是除氢以外具有3至约10个原子的支链或环状烷基; （d）W为O或S; 和（e）R是具有双键或三键的饱和或单或二不饱和的直链，支链或环状烷基或芳基，R除氢以外具有1至约15个原子; 包含这些化合物的药物组合物，以及使用这些化合物治疗炎症或疼痛的方法。

4. 发明申请

WO2012138752A2 EMERGENCY AND TRAFFIC ALERT SYSTEM 审中-公开
标题翻译：紧急和交通警报系统
公开(公告)号：WO2012138752A2
公开(公告)日：2012-10-11
申请号：PCT/US2012032161
申请日：2012-04-04
申请人： B & C ELECTRONIC ENGINEERING INC , GUTIERREZ JUAN , JOHNSON CARL
发明人： GUTIERREZ JUAN , JOHNSON CARL
IPC分类号： G08G1/0965 , G08G1/0969
CPC分类号： G08G1/096716 , G01C21/3691 , G01C21/3697 , G08G1/0965 , G08G1/096741 , G08G1/09675 , G08G1/096775 , G08G1/205
摘要： Systems and methods are disclosed for providing event notification to navigational applications and devices. An event notification system determines whether to send application information to a navigation application or device based upon the proximity of the device to the event. In other embodiments, the event notification system sends all event information to the device and the device determines whether or not to display the information based upon the proximity of the event to the device. User interfaces for displaying event information to a user are also disclosed. Finally, system and methods are disclosed for providing disaster related information to service providers who, in turn, send the disaster information to users of personal navigation devices. For example, information provided may include evacuation routes, shelter locations, disaster recovery centers, hospitals, points of distribution, economic recovery locations, etc.
摘要翻译：公开了用于向导航应用和设备提供事件通知的系统和方法。事件通知系统基于设备对事件的接近度确定是否将应用信息发送到导航应用或设备。在其他实施例中，事件通知系统将所有事件信息发送到设备，并且设备基于事件对设备的接近度来确定是否显示信息。还公开了向用户显示事件信息的用户界面。最后，公开了系统和方法，用于向服务提供商提供灾害相关信息，服务提供商又将灾难信息发送给个人导航设备的用户。例如，提供的信息可能包括撤离路线，住所位置，灾难恢复中心，医院，分配点，经济恢复位置等。

5. 发明申请

WO2010013168A1 3',6-SUBSTITUTED INDIRUBINS AND THEIR BIOLOGICAL APPLICATIONS 审中-公开
标题翻译： 3'，6替代的INDIRUBINS及其生物应用
公开(公告)号：WO2010013168A1
公开(公告)日：2010-02-04
申请号：PCT/IB2009/053153
申请日：2009-07-21
申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) , MEIJER, Laurent , SKALTSOUNIS, Leandros , MIKROS, Emmanuel , MAGIATIS, Prokopios , JOHNSON, Carl
发明人： MEIJER, Laurent , SKALTSOUNIS, Leandros , MIKROS, Emmanuel , MAGIATIS, Prokopios , JOHNSON, Carl
IPC分类号： C07D209/40 , A61K31/404 , A61P35/00 , A61P25/00
CPC分类号： C07D209/40
摘要： Indirubin derivatives of formula (I) wherein R represents - (A) n - R 1 or -CO-N(R 2 ,R 3 ) with • A being C1-C5 alkylene group, optionally substituted by one or several A 1 radical, A 1 being an halogen Br, OH, OR 4 or NH 2 , R 4 being C1-C5 alkyl; - R 1 being halogen, OH, N(R 2 , R 3 ); R 2 and R 3 , identical or different, being C 1 -C5 alkyl, optionally substituted by A 1 such as above defined, or R 2 and R 3 are part of a cycle with 5 or 6 elements optionally comprising another heteroatom such as O or N; • n = 1-5. It also relates to the biological application thereof.
摘要翻译：其中R表示 - （A）n-R 1或-CO-N（R 2，R 3）的式（I）的靛玉红衍生物，其中A为C1-C5亚烷基，任选被一个或几个A 1基团取代，A 1为卤素Br ，OH，OR 4或NH 2，R 4为C 1 -C 5烷基; -R 1为卤素，OH，N（R 2，R 3）; R2和R3相同或不同，为任选被如上定义的A1取代的C 1 -C 5烷基，或者R 2和R 3是具有5或6个元素的循环的一部分，任选地包含另外的杂原子如O或N; n = 1-5。它还涉及其生物应用。

6. 发明申请

WO9966324A9 A BIOLUMINESCENCE RESONANCE ENERGY TRANSFER (BRET) SYSTEM AND ITS USE 审中-公开
标题翻译：生物共振能量转移（BRET）系统及其使用
公开(公告)号：WO9966324A9
公开(公告)日：2000-07-13
申请号：PCT/CA9900561
申请日：1999-06-16
申请人： JOLY ERIK , JOHNSON CARL H , PISTON DAVID W
发明人： JOLY ERIK , JOHNSON CARL H , PISTON DAVID W
IPC分类号： C07K14/195 , C07K14/435 , C12N9/02 , C12N15/62 , G01N33/542 , G01N33/58 , C12Q1/66 , G01N33/50
CPC分类号： C12N9/0069 , C07K14/195 , C07K14/43595 , C07K2319/09 , C07K2319/72 , C07K2319/80 , C07K2319/90 , C12N15/62 , G01N33/542 , G01N2333/43595
摘要： This invention provides bioluminescence resonance energy transfer (BRET) system that comprises four parts: 1) a bioluminescent protein that has luciferase activity; 2) an acceptor fluorophore that can accept the energy from the bioluminescent protein when they are associated, in the presence of the appropriate substrate; 3) a modulator that influences the proximity or the orientation of the bioluminescent protein and the fluorophore, and 4) an appropriate substrate to activate the luciferase activity of the bioluminescent protein. The components of this system interact to influence the spatial relationship between the bioluminescent protein and the fluorophore, that is demonstrated by the light emission from the system. The modulator can be a single entity, covalently attached to both the bioluminescent protein and the fluorophore, it can be two separate entities, each linked covalently to either the bioluminescent protein or the fluorophore, or an alternative configuration that falls within the scope of the invention. Thissystem can be used in both in vivo or in vitro assays to detect molecular changes in a wide variety of applications, and is amenable to automation. In particular, it is useful for assaying protein interactions, enzyme activities and the concentration of analytes or signaling molecules in cells or in solution.
摘要翻译：本发明提供生物发光共振能量转移（BRET）系统，其包括四个部分：1）具有荧光素酶活性的生物发光蛋白; 2）受体荧光团，当在适当的底物存在下，可接受来自生物发光蛋白的能量; 3）影响生物发光蛋白和荧光团的接近度或取向的调节剂，以及4）活化生物发光蛋白的荧光素酶活性的合适底物。该系统的组分相互影响生物发光蛋白和荧光团之间的空间关系，这是由系统的光发射所证明的。调节剂可以是共价连接生物发光蛋白质和荧光团的单个实体，它可以是两个分开的实体，每个实体共价连接到生物发光蛋白质或荧光团，或属于本发明范围内的替代配置。该系统可用于体内或体外测定以检测各种应用中的分子变化，并且适于自动化。特别地，它可用于测定细胞或溶液中的蛋白质相互作用，酶活性和分析物或信号分子的浓度。

7. 发明申请

WO2011064632A3 PREPARATION OF SETTING SLURRIES 审中-公开
标题翻译：定型流程的准备
公开(公告)号：WO2011064632A3
公开(公告)日：2011-11-17
申请号：PCT/IB2010002658
申请日：2010-10-15
申请人： SCHLUMBERGER TECHNOLOGY BV , SCHLUMBERGER HOLDINGS , SCHLUMBERGER CA LTD , SCHLUMBERGER SERVICES PETROL , PRAD RES & DEV LTD , SCHLUMBERGER SEACO INC , VIDICK BENOIT , HARTSHORNE ROBERT SETH , LAWRENCE NATHAN , JOHNSON CARL , MONTEIRO GLEN , WOODROW JONATHAN
发明人： VIDICK BENOIT , HARTSHORNE ROBERT SETH , LAWRENCE NATHAN , JOHNSON CARL , MONTEIRO GLEN , WOODROW JONATHAN
IPC分类号： E21B33/14
CPC分类号： E21B33/14 , C04B40/0032 , C09K8/467 , C04B28/02 , C04B40/0039 , C04B2103/22
摘要： When preparing a settable slurry such as a cement slurry for cementing an oil well, cement or other solid powder is mixed with water and a set retarder. In order to be able to run a convenient and rapid check on the concentration of retarder after dilution at the site of use, a tracer material is mixed with the retarder in known amount during manufacture. The tracer is chosen to enable its concentration to be determined analytically after dilution at the site of use, thereby providing a way to determine the concentration of set retarder after such dilution. The tracer may be a redox-active material and its concentration may be determined by voltammetry. Tracer may likewise be mixed with additives other than set retarder.
摘要翻译：当准备可固化的浆料如用于固井的水泥浆料时，水泥或其它固体粉末与水和凝结缓凝剂混合。为了能够在使用地点对稀释后的缓凝剂的浓度进行方便快捷的检查，在制造过程中将示踪物质与已知量的缓凝剂混合。选择示踪剂以使其浓度在稀释后在使用部位分析确定，从而提供一种确定稀释后凝固缓凝剂浓度的方法。示踪剂可以是氧化还原活性物质，其浓度可以通过伏安法测定。示踪剂同样可以与除阻滞剂之外的添加剂混合。

8. 发明申请

WO2011064632A2 PREPARATION OF SETTING SLURRIES 审中-公开
标题翻译：准备条件的准备
公开(公告)号：WO2011064632A2
公开(公告)日：2011-06-03
申请号：PCT/IB2010/002658
申请日：2010-10-15
申请人： SCHLUMBERGER TECHNOLOGY B.V. , SCHLUMBERGER HOLDINGS LIMITED , SCHLUMBERGER CANADA LIMITED , SERVICES PETROLIERS SCHLUMBERGER , PRAD RESEARCH AND DEVELOPMENT LIMITED , SCHLUMBERGER SEACO, INC. , VIDICK, Benoit , HARTSHORNE, Robert, Seth , LAWRENCE, Nathan , JOHNSON, Carl , MONTEIRO, Glen , WOODROW, Jonathan
发明人： VIDICK, Benoit , HARTSHORNE, Robert, Seth , LAWRENCE, Nathan , JOHNSON, Carl , MONTEIRO, Glen , WOODROW, Jonathan
CPC分类号： E21B33/14 , C04B40/0032 , C09K8/467 , C04B28/02 , C04B40/0039 , C04B2103/22
摘要： When preparing a settable slurry such as a cement slurry for cementing an oil well, cement or other solid powder is mixed with water and a set retarder. In order to be able to run a convenient and rapid check on the concentration of retarder after dilution at the site of use, a tracer material is mixed with the retarder in known amount during manufacture. The tracer is chosen to enable its concentration to be determined analytically after dilution at the site of use, thereby providing a way to determine the concentration of set retarder after such dilution. The tracer may be a redox-active material and its concentration may be determined by voltammetry. Tracer may likewise be mixed with additives other than set retarder.
摘要翻译：在制备用于固井的水泥浆等可固化浆料时，将水泥或其它固体粉末与水和缓凝剂混合。为了能够在使用地点稀释后对缓凝剂的浓度进行方便快速的检查，在制造过程中将示踪剂材料与缓凝剂以已知量混合。选择示踪剂以使其浓度在使用位置稀释后分析测定，由此提供确定这种稀释后缓凝剂浓度的方法。示踪剂可以是氧化还原活性物质，其浓度可以通过伏安法测定。示踪剂也可以与除缓凝剂之外的添加剂混合。

9. 发明申请

WO2010111442A1 EMERGENCY AND TRAFFIC ALERT SYSTEM 审中-公开
标题翻译：紧急和交通警报系统
公开(公告)号：WO2010111442A1
公开(公告)日：2010-09-30
申请号：PCT/US2010/028572
申请日：2010-03-25
申请人： B&C ELECTRONIC ENGINEERING, INC. , GUTIERREZ, Juan , JOHNSON, Carl
发明人： GUTIERREZ, Juan , JOHNSON, Carl
IPC分类号： G08G1/00
CPC分类号： G08G1/096775 , G01C21/3697 , G08G1/0965
摘要： Systems and methods are disclosed for providing event notification to navigational applications. More specifically, the disclosed systems and methods provide emergency and non-emergency event information to users such that the event information is displayed to the user of a navigation application. For example, the location of an emergency event, such as a car accident or a fire is displayed on a personal navigation device. Furthermore, the real-time location of emergency vehicles responding to the event can be displayed on the navigation application. This provides additional information to drivers to help avoid traffic situations and clear the route for emergency vehicles. The disclosed systems and methods may also be employed to provide non-emergency information to users, such as parade or marathon information and routes, snow routes, evacuation routes, and traffic signal outages.
摘要翻译：公开了用于向导航应用提供事件通知的系统和方法。更具体地，所公开的系统和方法向用户提供紧急和非紧急事件信息，使得事件信息被显示给导航应用的用户。例如，在个人导航装置上显示诸如车祸或火灾的紧急事件的位置。此外，响应于事件的紧急车辆的实时位置可以显示在导航应用中。这为驾驶员提供了额外的信息，以帮助避免交通情况，并清除紧急车辆的路线。还可以使用公开的系统和方法来向用户提供非紧急信息，例如游行或马拉松信息和路线，雪道，疏散路线和交通信号中断。

10. 发明申请

WO2009158014A1 SYSTEM AND METHOD FOR PROVIDING COST TRANSPARENCY TO UNITS OF AN ORGANIZATION 审中-公开
标题翻译：提供组织成本透明度的系统和方法
公开(公告)号：WO2009158014A1
公开(公告)日：2009-12-30
申请号：PCT/US2009/003807
申请日：2009-06-26
申请人： BARCLAYS CAPITAL INC. , CASTLE, Julie , LOH, Anne , JOHNSON, Carl , KRISHNAPILLAI, Biju Kumar , SCANLON, Sharon
发明人： CASTLE, Julie , LOH, Anne , JOHNSON, Carl , KRISHNAPILLAI, Biju Kumar , SCANLON, Sharon
IPC分类号： G05B19/418
CPC分类号： G06Q10/10 , G06Q40/12
摘要： A system and method provide transparency of costs allocated to a unit of an organization. The method includes steps to receive asset information for an application at a cost transparency engine and identify a direct dependency of the application and an indirect dependency of the application using the asset information for the application. An infrastructure cost for the application is determined based on the direct dependency, the indirect dependency, component consumption by the application, and a unit cost of a service supporting the component. A report is generated, via a reporting tool, presenting the infrastructure cost for the application.
摘要翻译：系统和方法提供了分配给组织单位的成本的透明度。该方法包括以成本透明度引擎接收应用的资产信息的步骤，并且使用应用的资产信息来识别应用的直接依赖性和应用的间接依赖性。基于直接依赖性，间接依赖性，应用程序的组件消耗以及支持组件的服务的单位成本确定应用程序的基础架构成本。通过报告工具生成报告，介绍应用程序的基础架构成本。

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