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1. 发明专利

GB9424156D0 Timber post preservative applicator 未知
公开(公告)号：GB9424156D0
公开(公告)日：1995-01-18
申请号：GB9424156
申请日：1994-11-30
申请人： DUFFILL JOHN K , JOHNSON TONY

2. 发明申请

WO2007068474A1 (2,5-DIOXOIMIDAZOLIDIN-I-YL)-N-HYDROXY-ACETAMIDES AS METALLOPROTEINASE INHIBITORS 审中-公开
标题翻译：（2,5-DIOXOIMIDAZOLIDIN-I-YL）-N-羟基 - 乙酰胺作为金属蛋白酶抑制剂
公开(公告)号：WO2007068474A1
公开(公告)日：2007-06-21
申请号：PCT/EP2006/012019
申请日：2006-12-13
申请人： MEDIVIR AB , JIANGSU HENGRUI MEDICINE COMPANY LIMITED , WALLBERG, Hans , XU, Ming, Hua , LIN, Guo, Qiang , LEI, Xin, Sheng , SUN, Piaoyang , PARKES, Kevin , JOHNSON, Tony , SAMUELSSON, Bertil
发明人： WALLBERG, Hans , XU, Ming, Hua , LIN, Guo, Qiang , LEI, Xin, Sheng , SUN, Piaoyang , PARKES, Kevin , JOHNSON, Tony , SAMUELSSON, Bertil
IPC分类号： C07D233/74 , C07D233/78 , C07D233/76
CPC分类号： C07D233/78 , C07D233/76
摘要： The invention provides compounds of the formula (I) wherein the variables are as defined in the specification. The compounds of the invention are inhibitors of metalloproteinase MMP-12 and are among other things useful for the treatment of obstructive airway diseases, such as chronic obstructive pulmonary disease (COPD).
摘要翻译：本发明提供式（I）化合物，其中变量如说明书中所定义。本发明的化合物是金属蛋白酶MMP-12的抑制剂，其它可用于治疗阻塞性气道疾病如慢性阻塞性肺疾病（COPD）。

3. 发明申请

WO2004093616A2 CUTING BOARD FOR FOOD PRODUCTS 审中-公开
标题翻译：食品食品委员会
公开(公告)号：WO2004093616A2
公开(公告)日：2004-11-04
申请号：PCT/US2004/012148
申请日：2004-04-20
申请人： JOHNSON, Tony, A. , JOHNSON, Wayne, R.
发明人： JOHNSON, Tony, A. , JOHNSON, Wayne, R.
IPC分类号： A47J
CPC分类号： A47J47/005
摘要： Disclosed is a cutting board, comprising a body. The body defines a cutting surface. The cutting surface comprises a plurality of apertures extending through the body and a support structure separating each adjacent aperture of the plurality of apertures. The plurality of apertures allows fluid to drain from the cutting surface while the support structure grips the food item to minimize slippage on the surface during a cutting motion. The support structure includes one or more gripping edges for gripping a food item to resist horizontal shear forces exerted on the cutting surface. The plurality of apertures and the support structure define a substantially open matrix.
摘要翻译：公开了一种切割板，包括主体。主体定义切割表面。切割表面包括延伸穿过主体的多个孔和分隔多个孔的每个相邻孔的支撑结构。多个孔允许流体从切割表面排出，同时支撑结构握住食品以最小化在切割运动期间在表面上的滑动。支撑结构包括用于夹紧食品以抵抗施加在切割表面上的水平剪切力的一个或多个抓握边缘。多个孔和支撑结构限定基本上开放的矩阵。

4. 发明申请

WO9817628A3 A SOLID-PHASE TECHNOLOGY FOR THE PREPARATION OF AMIDES 审中-公开
标题翻译：一种用于制备AMIDES的固相技术
公开(公告)号：WO9817628A3
公开(公告)日：1998-09-03
申请号：PCT/GB9702914
申请日：1997-10-22
申请人： PEPTIDE THERAPEUTICS LTD , JOHNSON TONY , QUIBELL MARTIN
发明人： JOHNSON TONY , QUIBELL MARTIN
IPC分类号： C07D241/08 , C07B61/00 , C07C47/565 , C07C51/367 , C07C59/74 , C07C59/92 , C07C69/712 , C07C231/02 , C07C231/10 , C07C233/00 , C07K1/04 , C07K1/06 , C08F8/30 , C07C59/125 , C07C69/708 , C07K1/00
CPC分类号： C07C59/74 , C07C69/712 , C07C231/10 , C07K1/045 , C07K1/047
摘要： A method for the solid phase synthesis of compounds of formula (1), in which either or both of R1 or R2 are combinatorially variable by a process represented by scheme (4) and wherein: X is (a), (b), (c) or (d); Y is H or a side chain functional group protective moiety such as Fmoc; R21 is an intermediate form of R2 which is subsequently chemically transformed to give the desired R2; and n is between 2 and 12, preferably 4. The invention also provides compounds and combinatorial libraries of compounds of formula (1), as well as intermediate compounds for use in the method.

5. 发明申请

WO1997004004A1 CYSTEINE PROTEASE INHIBITORS FOR USE IN TREATMENT OF IgE MEDIATED ALLERGIC DISEASES 审中-公开
标题翻译：用于治疗IgE介导性过敏性疾病的CYSTEINE PROTEASE抑制剂
公开(公告)号：WO1997004004A1
公开(公告)日：1997-02-06
申请号：PCT/GB1996001707
申请日：1996-07-17
申请人： PEPTIDE THERAPEUTICS LIMITED , JOHNSON, Tony , HART, Terrance , LAING, Peter , SHAKIB, Farouk , QUIBELL, Martin
发明人： PEPTIDE THERAPEUTICS LIMITED
IPC分类号： C07K05/06
CPC分类号： C07K5/06052 , A61K38/00
摘要： The invention relates to compounds for use in the treatment of allergic diseases including juvenile asthma and eczema. The compounds can inhibit IgE mediated reaction to major environmental and occupational allergens. They can also have a prophylactic effect against allergic disease by preventing allergic sensitisation to environmental and occupational antigens when administered to at-risk individuals (e.g. those at genetic risk of asthma, and those exposed to occupational allergens in the workplace). The compounds of the invention can also be useful for inactivation or attenuation of the allergenicity of allergens in situ. The invention provides novel compounds and ligands per se, pharmaceutical compositions containing the compounds, processes for producing the compounds and pharmaceutical compositions, and methods for using the compounds and compositions in treatment or prophylaxis of IgE mediated allergic diseases and in inactivation or attenuation of allergens in situ. The invention also provides means for the reducing or destroying the viability of allergy-causing organisms.
摘要翻译：本发明涉及用于治疗过敏性疾病（包括幼年型哮喘和湿疹）的化合物。这些化合物可以抑制IgE介导的对主要环境和职业过敏原的反应。当对有风险的个体（例如那些患有哮喘的遗传风险和在工作场所暴露于职业过敏原的人）施用时，它们也可以通过防止对环境和职业抗原的过敏敏化来预防过敏性疾病。本发明的化合物还可用于失活或减轻原位过敏原的致敏性。本发明提供了新的化合物和配体本身，含有化合物的药物组合物，用于生产化合物的方法和药物组合物，以及使用该化合物和组合物治疗或预防IgE介导的过敏性疾病和灭活或减弱变应原的方法原位。本发明还提供了减少或破坏过敏生物的活力的方法。

6. 发明申请

WO2012027702A1 PYRIDYL-AMINE FUSED AZADECALIN MODULATORS 审中-公开
标题翻译：吡啶胺混合阿扎他林调节剂
公开(公告)号：WO2012027702A1
公开(公告)日：2012-03-01
申请号：PCT/US2011/049408
申请日：2011-08-26
申请人： CORCEPT THERAPEUTICS, INC. , CLARK, Robin , JOHNSON, Tony , HUNT, Hazel , MCDONALD, Ian
发明人： CLARK, Robin , JOHNSON, Tony , HUNT, Hazel , MCDONALD, Ian
IPC分类号： C07D471/00
CPC分类号： C07D471/04
摘要： The present invention provides a novel class of pyridyl-amine fused azadecalin compounds and methods of using the compounds as glucocorticoid receptor modulators.
摘要翻译：本发明提供了一类新颖的吡啶基 - 胺稠合的十九烷基化合物和使用该化合物作为糖皮质激素受体调节剂的方法。

7. 发明申请

WO2007063330A3 BAG 审中-公开
公开(公告)号：WO2007063330A3
公开(公告)日：2007-06-07
申请号：PCT/GB2006/004506
申请日：2006-12-04
申请人： TRI-BAG LIMITED , SMITH, Wendy , MYERS, Chris , JOHNSON, Tony , PROBEREZNY, Ken
发明人： MYERS, Chris , JOHNSON, Tony , PROBEREZNY, Ken
IPC分类号： A45C5/14 , A63B55/08
摘要： Apparatus (1) comprising a bag (22) having a base (6) adapted to receive a ground rolling device (100), said ground rolling device (100) being detachably connectable to the base (6) and comprising an axle (16) provided with a wheel (17a, 17b) at or adjacent each end such that when the ground rolling device (100) is connected to the base (6) the wheels (17a, 17b) project laterally from either side of the base (6).

8. 发明申请

WO2012044673A1 POWER MONITORING DEVICE SIMULATION USING A DATABASE PROFILE GENERATED FROM REAL TIME-VALUE DATA 审中-公开
标题翻译：使用实时数据生成的数据库配置文件进行电力监控设备的仿真
公开(公告)号：WO2012044673A1
公开(公告)日：2012-04-05
申请号：PCT/US2011/053659
申请日：2011-09-28
申请人： SCHNEIDER ELECTRIC USA, INC. , LLOYD, Chad, Andrew , JOHNSON, Tony , MCQUILLAN, Jayme
发明人： LLOYD, Chad, Andrew , JOHNSON, Tony , MCQUILLAN, Jayme
IPC分类号： G05B23/02
CPC分类号： G05B23/0213
摘要： A system and methods for using data from an external database compiled from real device used for testing and simulation of a system. The system includes an external database interface to access an external database. The external database includes a plurality of categories of time-value data collected from an electrical device. An importer converts one of plurality of categories of time-value data to a corresponding topic of a common data format. A device profiler is coupled to the importer to create a device profile including the converted topic. A database profiler creates a database profile representing a system including a device defined by the device profile and including the category of time-value data.
摘要翻译：用于从用于测试和模拟系统的实际设备编译的外部数据库中使用数据的系统和方法。该系统包括一个用于访问外部数据库的外部数据库接口。外部数据库包括从电气设备收集的多个类别的时间值数据。导入器将多个类别的时间值数据中的一个转换为公共数据格式的相应主题。设备分析器耦合到导入器以创建包括转换的主题的设备简档。数据库分析器创建表示包括由设备配置文件定义并且包括时间值数据类别的设备的系统的数据库配置文件。

9. 发明申请

WO2011086053A1 TRICYCLIC HETEROCYCLIC COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF 审中-公开
标题翻译：三元杂环化合物，组合物及其使用方法
公开(公告)号：WO2011086053A1
公开(公告)日：2011-07-21
申请号：PCT/EP2011/050239
申请日：2011-01-11
申请人： F. HOFFMANN-LA ROCHE AG , BABU, Srinivasan , BERGERON, Phillippe , DRAGOVICH, Peter , DYKE, Hazel Joan , GIBBONS, Paul , GRADL, Stefan , HANAN, Emily , HURLEY, Christopher , JOHNSON, Tony , KOEHLER, Michael , KULAGOWSKI, Janusz Josef , LABADIE, Sharada Shenvi , LYSSIKATOS, Joseph P. , MENDONCA, Rohan , PULK, Rebecca , WARD, Stuard , WASZKOWYCZ, Bohdan , ZAK, Mark
发明人： BABU, Srinivasan , BERGERON, Phillippe , DRAGOVICH, Peter , DYKE, Hazel Joan , GIBBONS, Paul , GRADL, Stefan , HANAN, Emily , HURLEY, Christopher , JOHNSON, Tony , KOEHLER, Michael , KULAGOWSKI, Janusz Josef , LABADIE, Sharada Shenvi , LYSSIKATOS, Joseph P. , MENDONCA, Rohan , PULK, Rebecca , WARD, Stuard , WASZKOWYCZ, Bohdan , ZAK, Mark
IPC分类号： C07D471/14 , C07D487/10 , A61K31/437 , A61P11/06 , A61P17/06 , A61P19/02 , A61P37/00 , A61P37/06
CPC分类号： C07D471/14 , C07D487/10
摘要： The invention provides novel compounds of formula (I) having the general formula, wherein R 1 , R 2 , R 3 , X and Y are as described herein. Accordingly, the compounds may be provided in pharmaceutically acceptable compositions and used for the treatment of immunological or hyperproliferative disorders.
摘要翻译：本发明提供具有以下通式的新的式（I）化合物：其中R 1，R 2，R 3，X和Y如本文所述。因此，化合物可以以药学上可接受的组合物提供，并用于治疗免疫学或过度增殖性疾病。

10. 发明申请

WO2008114054A1 PROTEASE INHIBITORS 审中-公开
标题翻译： PROTEASE抑制剂
公开(公告)号：WO2008114054A1
公开(公告)日：2008-09-25
申请号：PCT/GB2008/050193
申请日：2008-03-18
申请人： MEDIVIR AB , KANGASMETSA, Jussi , PARKES, Kevin , TOZER, Matt , JOHNSON, Tony , GRABOWSKA, Urszula , ODEN, Lourdes , SUND, Christian , NILSSON, Magnus , IVANOV, Vladimir , KAHNBERG, Pia
发明人： KANGASMETSA, Jussi , PARKES, Kevin , TOZER, Matt , JOHNSON, Tony , GRABOWSKA, Urszula , ODEN, Lourdes , SUND, Christian , NILSSON, Magnus , IVANOV, Vladimir , KAHNBERG, Pia
IPC分类号： C07D491/04 , A61K31/407 , A61P19/00
CPC分类号： C07D491/04
摘要： Compounds of the formula (II): wherein R 2 is the side chain of leucine, isoleucine, cyclohexylglycine, O-methyl threonine, 4-fluoroleucine or 3-methoxyvaline; R 3 is H, methyl or fluoro; R 4 is C 1 -C 6 alkyl; E is a bond or thiazolyl, optionally substituted with methyl or fluoro; n is 0 or 1; or a pharmaceutically acceptable salt, N-oxide or hydrate thereof; have utility in the treatment of disorders characterized by inappropriate expression or activation of cathepsinK, such as osteoporosis, osteoarthritis, rheumatoid arthritis or bone metastases.
摘要翻译：式（II）的化合物：其中R 2是亮氨酸的侧链，异亮氨酸，环己基甘氨酸，O-甲基苏氨酸，4-氟代亮氨酸或3-甲氧基缬氨酸; R 3是H，甲基或氟; R 4是C 1 -C 6烷基; R 4是C 1 -C 6烷基; E是任选被甲基或氟取代的键或噻唑基; n为0或1; 或其药学上可接受的盐，N-氧化物或其水合物; 可用于治疗特征为组织蛋白酶K不适当表达或活化的疾病，例如骨质疏松症，骨关节炎，类风湿性关节炎或骨转移。

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