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1. 发明申请

US20130313737A1 NOVEL COMPOSITION FOR PREPARING POLYSACCHARIDE FIBERS 有权
标题翻译：制备多糖纤维的新型组合物
公开(公告)号：US20130313737A1
公开(公告)日：2013-11-28
申请号：US13479990
申请日：2012-05-24
申请人： John P. O'BRIEN
发明人： John P. O'BRIEN
IPC分类号： C08L5/00
CPC分类号： D01D5/06 , C08B37/0021 , C08L5/00 , C08L5/02 , D01F9/00 , D01F11/00
摘要： Solutions formed by combining poly(α(1→3) glucan) with CS2 in aqueous alkali metal hydroxide solution have been shown to produce the xanthated form of the poly(+(1→3) glucan). The solutions so formed have been shown to be useful for solution spinning into fiber of poly(α(1→3) glucan) when the spun fiber is coagulated in an acidic coagulation bath. The fibers so produced exhibit desirable physical properties. The poly(α(1→3) glucan) employed was synthesized by fermentation.
摘要翻译：已经显示通过在碱金属氢氧化物水溶液中将聚（α（1→3）葡聚糖）与CS2结合形成的溶液产生聚（+（1-> 3）葡聚糖）的黄原酸形式。当纺丝纤维在酸性凝固浴中凝结时，这样形成的溶液已被证明可用于溶液纺丝成聚（α（1→3）葡聚糖纤维）。如此制备的纤维表现出所需的物理性质。所用的聚（α（1→3）葡聚糖）是通过发酵合成的。

2. 发明授权

US08318659B2 Peptide-based organic sunscreens 失效
标题翻译：基于肽的有机防晒剂
公开(公告)号：US08318659B2
公开(公告)日：2012-11-27
申请号：US11590717
申请日：2006-10-31
申请人： David J. Lowe , John P. O'Brien , Antoinette E. Wilkins
发明人： David J. Lowe , John P. O'Brien , Antoinette E. Wilkins
IPC分类号： A61K38/00 , A61K38/04 , A61K8/00 , A61K8/18 , A61K8/64 , A61K8/65 , C07K5/00 , C07K7/00 , C07K16/00 , C07K17/00 , A61Q17/04
CPC分类号： A61Q17/04 , A61K8/64 , A61K2800/57 , C07K7/06 , C07K7/08
摘要： Peptide-based organic sunscreens, formed by coupling a skin-binding peptide with an organic sunscreen agent, are described. The skin-binding peptide part of the peptide-based organic sunscreen binds strongly to the skin, thus keeping the organic sunscreen agent attached to the skin for long lasting protection. Sunscreen compositions comprising the peptide-based organic sunscreens are also provided.
摘要翻译：描述了通过将皮肤结合肽与有机防晒剂偶联形成的肽类有机防晒剂。基于肽的有机防晒剂的皮肤结合肽部分强烈地与皮肤结合，从而保持有机防晒剂附着在皮肤上以获得持久的保护。还提供了包含基于肽的有机防晒剂的防晒组合物。

3. 发明申请

US20120073886A1 ROBOTIC VEHICLE 有权
标题翻译：机动车
公开(公告)号：US20120073886A1
公开(公告)日：2012-03-29
申请号：US12838824
申请日：2010-07-19
申请人： Adam P. Couture , Richard Page , John P. O'Brien , Mikhail Filippov
发明人： Adam P. Couture , Richard Page , John P. O'Brien , Mikhail Filippov
IPC分类号： B62D55/075 , B60L11/18
CPC分类号： B25J5/005 , B62D25/2054 , B62D55/065 , B62D55/0655
摘要： A robotic vehicle is disclosed, which is characterized by high mobility, adaptability, and the capability of being remotely controlled in hazardous environments. The robotic vehicle includes a chassis having front and rear ends and supported on right and left driven tracks. Right and left elongated flippers are disposed on corresponding sides of the chassis and operable to pivot. A linkage connects a payload deck, configured to support a removable functional payload, to the chassis. The linkage has a first end rotatably connected to the chassis at a first pivot, and a second end rotatably connected to the deck at a second pivot. Both of the first and second pivots include independently controllable pivot drivers operable to rotatably position their corresponding pivots to control both fore-aft position and pitch orientation of the payload deck with respect to the chassis.
摘要翻译：公开了一种机动车辆，其特征在于高度的移动性，适应性以及在危险环境中被远程控制的能力。机器人车辆包括具有前端和后端并支撑在右和左驱动轨道上的底盘。右和左细长鳍状物设置在底盘的相应侧上并可操作以枢转。一个链接将一个配置成支持可移动功能有效载荷的有效载荷甲板连接到机箱。联动装置具有在第一枢轴处可转动地连接到底盘的第一端，以及在第二枢轴处可旋转地连接到甲板的第二端。第一枢轴和第二枢轴都包括可独立控制的枢转驱动器，其可操作以可旋转地定位其对应的枢轴以控制有效载荷甲板相对于底盘的前后位置和俯仰方位。

4. 发明授权

US07964180B2 Method for enhancing effects of colorants and conditioners 有权
标题翻译：增强着色剂和调理剂效果的方法
公开(公告)号：US07964180B2
公开(公告)日：2011-06-21
申请号：US12754630
申请日：2010-04-06
申请人： William A. Beck , John P. O'Brien , Hong Wang
发明人： William A. Beck , John P. O'Brien , Hong Wang
IPC分类号： A61Q5/12
CPC分类号： A61K8/64 , A61K2800/94 , A61Q3/00 , A61Q5/10 , A61Q17/005 , A61Q17/04 , A61Q19/00 , A61Q19/04 , C07K2319/00
摘要： Methods are provided for enhancing the longevity of the binding of various benefit agents to hair and skin. Applications of traditional and non-traditional colorants and conditioners to hair and skin are amended with compositions of hair or skin-binding peptides respectively. The presence of the hair or skin-binding peptide compositions act to increase the longevity of the applied colorant or conditioner on the hair or skin.
摘要翻译：提供了用于增强各种有益剂与头发和皮肤结合的寿命的方法。传统和非传统着色剂和调理剂对毛发和皮肤的应用分别用头发或皮肤结合肽的组合物修饰。头发或皮肤结合肽组合物的存在用于增加所施用的着色剂或护发素在头发或皮肤上的寿命。

5. 发明申请

US20110052508A1 PEPTIDE-BASED ORAL CARE SURFACE REAGENTS FOR PERSONAL CARE 失效
标题翻译：基于肽的口腔护理面部个人护理试剂
公开(公告)号：US20110052508A1
公开(公告)日：2011-03-03
申请号：US12853436
申请日：2010-08-10
申请人： Xueying Huang , John P. O'Brien , Hong Wang
发明人： Xueying Huang , John P. O'Brien , Hong Wang
IPC分类号： A61K8/21 , C07K7/08 , C07K14/00 , C07K7/06 , A61K8/64 , A61Q11/00 , C12N9/96 , B82Y5/00
CPC分类号： A61K8/29 , A61K8/64 , A61K2800/413 , A61K2800/42 , A61K2800/57 , A61K2800/94 , A61Q1/02 , A61Q1/10 , A61Q3/00 , A61Q5/065 , A61Q5/12 , A61Q11/00 , A61Q17/04 , A61Q19/00 , A61Q19/04 , B82Y5/00 , C07K7/06 , C07K7/08
摘要： Peptides have been identified that bind to oral surfaces such as teeth and gums. Peptide based oral care reagents have been created by couple such peptides to oral care benefit agents such as whiteners.
摘要翻译：已经鉴定了结合口腔表面如牙齿和牙龈的肽。基于肽的口腔护理试剂已经通过将这些肽与口腔护理有益剂如增白剂相结合而形成。

6. 发明授权

US07858581B2 PMMA binding peptides and methods of use 有权
标题翻译： PMMA结合肽及其使用方法
公开(公告)号：US07858581B2
公开(公告)日：2010-12-28
申请号：US11607732
申请日：2006-12-01
申请人： Scott D. Cunningham , David J. Lowe , John P. O'Brien , Hong Wang , Antoinette E. Wilkins
发明人： Scott D. Cunningham , David J. Lowe , John P. O'Brien , Hong Wang , Antoinette E. Wilkins
IPC分类号： A61K38/02 , C10M145/14
CPC分类号： C07K7/08 , C07K7/06 , C07K14/001
摘要： Combinatorially generated peptides are provided that have binding affinity for polymethylmethacrylate (PMMA). The peptides may be used to deliver benefit agents to various PMMA surfaces.
摘要翻译：提供了对聚甲基丙烯酸甲酯（PMMA）具有结合亲和力的组合产生的肽。肽可以用于将有益剂递送到各种PMMA表面。

7. 发明授权

US07807141B2 Peptide-based oral care surface reagents for personal care 有权
标题翻译：用于个人护理的基于肽的口腔护理表面试剂
公开(公告)号：US07807141B2
公开(公告)日：2010-10-05
申请号：US11971975
申请日：2008-01-10
申请人： Xueying Huang , John P. O'Brien , Hong Wang
发明人： Xueying Huang , John P. O'Brien , Hong Wang
IPC分类号： A61K8/64 , A61K11/00 , C07K7/08
CPC分类号： A61K8/29 , A61K8/64 , A61K2800/413 , A61K2800/42 , A61K2800/57 , A61K2800/94 , A61Q1/02 , A61Q1/10 , A61Q3/00 , A61Q5/065 , A61Q5/12 , A61Q11/00 , A61Q17/04 , A61Q19/00 , A61Q19/04 , B82Y5/00 , C07K7/06 , C07K7/08
摘要： Peptides have been identified that bind to oral surfaces such as teeth and gums. Peptide based oral care reagents have been created by couple such peptides to oral care benefit agents such as whiteners.
摘要翻译：已经鉴定了结合口腔表面如牙齿和牙龈的肽。基于肽的口腔护理试剂已经通过将这些肽与口腔护理有益剂如增白剂相结合而形成。

8. 发明申请

US20100189670A1 METHOD FOR ENHANCING EFFECTS OF COLORANTS AND CONDITIONERS 有权
标题翻译：提高颜料和调色剂效果的方法
公开(公告)号：US20100189670A1
公开(公告)日：2010-07-29
申请号：US12754630
申请日：2010-04-06
申请人： WILLIAM A. BECK , JOHN P. O'BRIEN , HONG WANG
发明人： WILLIAM A. BECK , JOHN P. O'BRIEN , HONG WANG
IPC分类号： A61K8/64 , C07K14/00 , A61K8/89 , A61K8/92 , A61K8/98 , A61K8/87 , A61Q5/12 , A61Q5/10 , A61Q5/00 , A61Q19/00 , A61Q1/02
CPC分类号： A61K8/64 , A61K2800/94 , A61Q3/00 , A61Q5/10 , A61Q17/005 , A61Q17/04 , A61Q19/00 , A61Q19/04 , C07K2319/00
摘要： Methods are provided for enhancing the longevity of the binding of various benefit agents to hair and skin. Applications of traditional and non-traditional colorants and conditioners to hair and skin are amended with compositions of hair or skin-binding peptides respectively. The presence of the hair or skin-binding peptide compositions act to increase the longevity of the applied colorant or conditioner on the hair or skin.
摘要翻译：提供了用于增强各种有益剂与头发和皮肤结合的寿命的方法。传统和非传统着色剂和调理剂对毛发和皮肤的应用分别用头发或皮肤结合肽的组合物修饰。头发或皮肤结合肽组合物的存在用于增加所施用的着色剂或护发素在头发或皮肤上的寿命。

9. 发明申请

US20090142283A1 PEPTIDE-BASED ANTIDANDRUFF REAGENTS 审中-公开
标题翻译：基于肽的抗转移试剂
公开(公告)号：US20090142283A1
公开(公告)日：2009-06-04
申请号：US12273753
申请日：2008-11-19
申请人： John P. O'Brien , Hong Wang , Antoinette E. Wilkins
发明人： John P. O'Brien , Hong Wang , Antoinette E. Wilkins
IPC分类号： A61K8/64 , C07K14/00 , A61K38/16
CPC分类号： A61K8/64 , A61Q5/006 , C07K7/06 , C07K7/08
摘要： Peptide-based antidandruff reagents, formed by coupling a skin-binding peptide with an antidandruff agent, are described. The skin-binding peptide part of the peptide-based antidandruff reagent binds strongly to the skin, thus keeping the antidandruff agent coupled to the skin for a long lasting effect. Hair care compositions comprising the peptide-based antidandruff reagents are also provided as well as methods for treating or preventing dandruff.
摘要翻译：描述了通过将皮肤结合肽与抗头皮屑剂偶联而形成的基于肽的去头皮屑试剂。基于肽的去头皮屑试剂的皮肤结合肽部分强烈地与皮肤结合，从而使去头皮屑剂与皮肤偶联以持久的效果。还提供了包含基于肽的去头皮屑试剂的护发组合物以及用于治疗或预防头皮屑的方法。

10. 发明授权

US07434515B2 Signal transmission fuse 失效
标题翻译：信号传输保险丝
公开(公告)号：US07434515B2
公开(公告)日：2008-10-14
申请号：US11452571
申请日：2006-06-14
申请人： John P. O'Brien
发明人： John P. O'Brien
IPC分类号： C06C5/04
CPC分类号： C06C5/04
摘要： A small diameter shock tube of unique internal surface configuration such that the powder loading per meter of tubing can be higher than achieved with conventional shock tube. The outside diameter of the tube is less than 0.10″, preferably 0.085″ with inner and outer layers of different polymeric material bonded together in a coextrusion process. The inside surface of the shock tube has radially inwardly projecting ribs or protuberances that result in an increase of the internal perphi of the inner surface cross section achieving a 30% increase so that powder loading per meter of the tube can be kept in a safe range.
摘要翻译：具有独特内表面构造的小直径冲击管，使得每米管道的粉末负载可高于用传统冲击管实现的粉末负荷。管的外径小于0.10“，优选为0.085”，其中不同聚合材料的内层和外层在共挤出方法中结合在一起。冲击管的内表面具有径向向内突出的肋或突起，其导致内表面横截面的内部弯曲增加，达到30％的增加，使得每米管的粉末负载能够保持在安全范围内。

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