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1. 发明专利

IL232973A Pharmaceutical compositions for controlled drug release containing chelating complex micelles and uses thereof 未知
公开(公告)号：IL232973A
公开(公告)日：2018-06-28
申请号：IL23297314
申请日：2014-06-05
申请人： ORIGINAL BIOMEDICALS CO LTD , CHIA HUNG CHEN , CHAU HUI WANG , JOHN SON LIN , TIEH HSIUNG CHIU , JING YI CHEN , PI HUNG LIAO , CHIA CHI SU , WEI CHUAN LIAO
IPC分类号： A61K20060101
摘要： This invention provides the controlled-release method for a pharmaceutical composition comprising of metals in the drug carrier. The specific chelator is used to trigger the release of active pharmaceutical ingredients from chelating complex micelles. The drug release rate and half-life can also be controlled by manipulating the dosing sequence and the concentration of metal and specific chelator.

2. 发明专利

CA2854927A1 THE CONTROLLED RELEASE METHOD FOR A PHARMACEUTICAL COMPOSITION COMPOSED OF CHELATING COMPLEX MICELLES 未知
公开(公告)号：CA2854927A1
公开(公告)日：2014-03-06
申请号：CA2854927
申请日：2013-01-31
申请人： ORIGINAL BIOMEDICALS CO LTD , CHIA-HUNG CHEN , CHAU-HUI WANG , JOHN-SON LIN , TIEH-HSIUNG CHIU , JING-YI CHEN , PI-HUNG LIAO , CHIA-CHI SU , WEI-CHUAN LIAO
发明人： CHIA-HUNG CHEN , CHAU-HUI WANG , JOHN-SON LIN , TIEH-HSIUNG CHIU , JING-YI CHEN , PI-HUNG LIAO , CHIA-CHI SU , WEI-CHUAN LIAO
IPC分类号： A61K9/107 , A61K31/16 , A61K31/496 , A61K31/661 , A61K31/704 , A61K38/14 , A61K47/02 , A61K47/30
摘要： This invention provides the controlled-release method for a pharmaceutical composition comprising of metals in the drug carrier. The specific chelator is used to trigger the release of active pharmaceutical ingredients from chelating complex micelles. The drug release rate and half-life can also be controlled by manipulating the dosing sequence and the concentration of metal and specific chelator.

3. 发明专利

AU2013309496A1 The controlled release method for a pharmaceutical composition composed of chelating complex micelles 未知
公开(公告)号：AU2013309496A1
公开(公告)日：2014-06-05
申请号：AU2013309496
申请日：2013-01-31
申请人： CHAU HUI WANG , CHIA CHI SU , CHIA HUNG CHEN , JING YI CHEN , JOHN SON LIN , ORIGINAL BIOMEDICALS CO LTD , PI HUNG LIAO , TIEH HSIUNG CHIU , WEI CHUAN LIAO
发明人： CHIA-HUNG CHEN , CHAU-HUI WANG , JOHN-SON LIN , TIEH-HSIUNG CHIU , JING-YI CHEN , PI-HUNG LIAO , CHIA-CHI SU , WEI-CHUAN LIAO
IPC分类号： A61K47/32 , A61K31/28 , A61K33/24
摘要： This invention provides the controlled-release method for a pharmaceutical composition comprising of metals in the drug carrier. The specific chelator is used to trigger the release of active pharmaceutical ingredients from chelating complex micelles. The drug release rate and half-life can also be controlled by manipulating the dosing sequence and the concentration of metal and specific chelator.

4. 发明专利

IL232973D0 Method for controlled release of a pharmaceutical composition composed of chelating complex micelles 未知
公开(公告)号：IL232973D0
公开(公告)日：2014-07-31
申请号：IL23297314
申请日：2014-06-05
申请人： ORIGINAL BIOMEDICALS CO LTD , CHIA HUNG CHEN , CHAU HUI WANG , JOHN SON LIN , TIEH HSIUNG CHIU , JING YI CHEN , PI HUNG LIAO , CHIA CHI SU , WEI CHUAN LIAO
IPC分类号： A61K20060101
摘要： This invention provides the controlled-release method for a pharmaceutical composition comprising of metals in the drug carrier. The specific chelator is used to trigger the release of active pharmaceutical ingredients from chelating complex micelles. The drug release rate and half-life can also be controlled by manipulating the dosing sequence and the concentration of metal and specific chelator.

5. 发明申请

WO2014035465A1 THE CONTROLLED RELEASE METHOD FOR A PHARMACEUTICAL COMPOSITION COMPOSED OF CHELATING COMPLEX MICELLES 审中-公开
标题翻译：用于组合复合细胞的药物组合物的控制释放方法
公开(公告)号：WO2014035465A1
公开(公告)日：2014-03-06
申请号：PCT/US2013/024049
申请日：2013-01-31
申请人： ORIGINAL BIOMEDICALS CO., LTD. , CHIA-HUNG, Chen , CHAU-HUI, Wang , JOHN-SON, LIn , TIEH-HSIUNG, Chiu , JING-YI, Chen , PI-HUNG, Liao , CHIA-CHI, Su , WEI-CHUAN, Liao
发明人： CHIA-HUNG, Chen , CHAU-HUI, Wang , JOHN-SON, LIn , TIEH-HSIUNG, Chiu , JING-YI, Chen , PI-HUNG, Liao , CHIA-CHI, Su , WEI-CHUAN, Liao
IPC分类号： A61K47/32 , A61K31/28 , A61K33/24
CPC分类号： A61K47/48215 , A61K9/1075 , A61K9/5115 , A61K9/5153 , A61K31/164 , A61K31/198 , A61K31/496 , A61K31/661 , A61K31/704 , A61K38/14 , A61K47/02 , A61K47/183 , A61K47/22 , Y02A50/402 , A61K2300/00
摘要： This invention provides the controlled-release method for a pharmaceutical composition comprising of metals in the drug carrier. The specific chelator is used to trigger the release of active pharmaceutical ingredients from chelating complex micelles. The drug release rate and half-life can also be controlled by manipulating the dosing sequence and the concentration of metal and specific chelator.
摘要翻译：本发明提供了包含药物载体中的金属的药物组合物的控释方法。特异性螯合剂用于引发活性药物成分从螯合复合胶束的释放。药物释放速率和半衰期也可以通过操纵给药顺序和金属和特异性螯合剂的浓度来控制。

6. 发明授权

US08269408B2 LED base structure with embedded capacitor 失效
标题翻译： LED基座结构，带嵌入式电容器
公开(公告)号：US08269408B2
公开(公告)日：2012-09-18
申请号：US13003702
申请日：2008-08-12
申请人： Ming-Hung Chen , Shih-Yi Wen , Jing-Yi Chen
发明人： Ming-Hung Chen , Shih-Yi Wen , Jing-Yi Chen
IPC分类号： H01L33/62 , H01L33/36 , H01L33/00
CPC分类号： H01L33/486 , H01L25/0753 , H01L25/167 , H01L33/62 , H01L2924/0002 , H05B33/0821 , H01L2924/00
摘要： An LED base structure with an embedded capacitor includes a body, at least one pair of metal layers, at least one dielectric layer, and at least two conductive channels. The body is an insulating base. The metal layers are disposed in the body, and the dielectric layer is disposed between the metal layers, so as to form an embedded capacitor. The conductive channels are electrically connected to the metal layers, respectively. The LED base structure is further electrically connected to a resistor for forming a resistor-capacitor delay circuit whereby a phase delay is effectuated whenever AC power is supplied to the LED base structure, so as to control the time for switching on one of two parallel-connected LEDs and, as a result, prevent the LEDs from flashing which might otherwise arise when the LEDs are supplied with AC power.
摘要翻译：具有嵌入式电容器的LED基座结构包括主体，至少一对金属层，至少一个电介质层和至少两个导电沟道。身体是绝缘基座。金属层设置在主体中，并且电介质层设置在金属层之间，以便形成嵌入式电容器。导电通道分别电连接到金属层。 LED基座结构进一步电连接到用于形成电阻器 - 电容器延迟电路的电阻器，由此每当向LED基座结构提供AC电力时，实现相位延迟，以便控制用于切换两个并联电路中的一个的时间，连接的LED，从而防止LED闪烁，否则当LED被提供交流电源时可能会发生。

7. 发明授权

US08207001B2 Manufacturing method for an axially symmetric light-emitting diode assembly 有权
标题翻译：轴对称发光二极管组件的制造方法
公开(公告)号：US08207001B2
公开(公告)日：2012-06-26
申请号：US13054272
申请日：2008-09-23
申请人： Ming-Hung Chen , Jing-Yi Chen
发明人： Ming-Hung Chen , Jing-Yi Chen
IPC分类号： H01L33/00
CPC分类号： H01L27/156 , H01L33/08 , H01L33/62 , H01L2924/0002 , H01L2924/00
摘要： A manufacturing method for an axially symmetric light-emitting diode assembly disclosed herein includes steps of: providing a substrate; and forming a plurality of light-emitting areas on the substrate. The substrate has a central axis. The light-emitting areas are arranged with axial symmetry around the central axis while being insulated from each other. Each of the light-emitting areas has at least one light-emitting diode, and the light-emitting diodes are electrically connected to each other. Since the light-emitting areas are formed on the substrate with the axially symmetric arrangement, the axially symmetric light-emitting diode assembly can present a well symmetric light pattern.
摘要翻译：本文公开的轴对称发光二极管组件的制造方法包括以下步骤：提供基板; 以及在所述基板上形成多个发光区域。基板具有中心轴。发光区域围绕中心轴线对称布置，同时彼此绝缘。每个发光区域具有至少一个发光二极管，并且发光二极管彼此电连接。由于发光区域形成在具有轴对称布置的基板上，所以轴对称发光二极管组件可以呈现良好对称的光图案。

8. 发明申请

US20110121329A1 AC LED Structure 审中-公开
标题翻译：交流LED结构
公开(公告)号：US20110121329A1
公开(公告)日：2011-05-26
申请号：US13003714
申请日：2008-08-06
申请人： Ming-Hung Chen , Shih-Yi Wen , Jing-Yi Chen
发明人： Ming-Hung Chen , Shih-Yi Wen , Jing-Yi Chen
IPC分类号： H01L27/15
CPC分类号： H01L25/0753 , H01L33/20 , H01L33/385 , H01L33/62 , H01L2924/0002 , H01L2924/00
摘要： An AC LED structure includes an insulating substrate, an LED set, a first metal layer and a second metal layer. The LED set has a first light-emitting diode and a second light-emitting diode, which are deposited on the insulating substrate and insulated from each other. The first metal layer and the second metal layer commonly have a first profile and serve to electrically connect the first light-emitting diode and the second light-emitting diode in an inverse parallel connection. In virtue of the first metal layer and the second metal layer of the first profile deposited on the first light-emitting diode and the second light-emitting diode, the LED set is allowed to be connected in series or in parallel with another LED set according to practical needs, so as to be able to endure high current density or high voltage operation.
摘要翻译： AC LED结构包括绝缘基板，LED组，第一金属层和第二金属层。 LED组具有第一发光二极管和第二发光二极管，其沉积在绝缘基板上并彼此绝缘。第一金属层和第二金属层通常具有第一轮廓并且用于以反并联方式电连接第一发光二极管和第二发光二极管。通过沉积在第一发光二极管和第二发光二极管上的第一轮廓的第一金属层和第二金属层，允许LED组与另一个LED组串联或并联连接，根据满足实际需要，以便能够承受高电流密度或高电压操作。

9. 发明申请

US20120018773A1 ALTERNATING-CURRENT LIGHT EMITTING DIODE STRUCTURE WITH OVERLOAD PROTECTION 审中-公开
标题翻译：具有过载保护功能的交流发光二极管结构
公开(公告)号：US20120018773A1
公开(公告)日：2012-01-26
申请号：US13258627
申请日：2009-04-07
申请人： Jing-Yi Chen , Shih-Yi Wen , Ching-Jen Pan , Ming-Hung Chen
发明人： Jing-Yi Chen , Shih-Yi Wen , Ching-Jen Pan , Ming-Hung Chen
IPC分类号： H01L33/64
CPC分类号： H05B33/0821 , H01L2224/48091 , H01L2224/73265 , H05B33/0803 , H05B33/089 , Y02B20/341 , H01L2924/00014
摘要： The present invention relates to an alternating current (AC) light emitting diode (LED) structure with overload protection, which comprises an AC LED, a heat dissipating unit and an overload protecting unit. The AC LED is thermally connected with the heat dissipating unit, and the overload protecting unit is connected in series between the AC LED and a power source. Thus, when an overload current is inputted to the AC LED structure, the temperature of the overload protecting unit will rise to disconnect the AC LED from the power source. In this way, an open-circuit status can be produced timely in the AC LED structure to block the power input into the AC LED for purpose of protection against overload.
摘要翻译：本发明涉及具有过载保护的交流（AC）发光二极管（LED）结构，其包括AC LED，散热单元和过载保护单元。交流LED与散热单元热连接，过载保护单元串联连接在交流LED和电源之间。因此，当过载电流被输入到AC LED结构时，过载保护单元的温度将升高以将AC LED与电源断开。以这种方式，可以在AC LED结构中及时产生开路状态，以阻断AC LED的电力输入，以防止过载。

10. 发明申请

US20110121723A1 LED Base Structure with Embedded Capacitor 失效
标题翻译：嵌入式电容器的LED基座结构
公开(公告)号：US20110121723A1
公开(公告)日：2011-05-26
申请号：US13003702
申请日：2008-08-12
申请人： Ming-Hung Chen , Shih-Yi Wen , Jing-Yi Chen
发明人： Ming-Hung Chen , Shih-Yi Wen , Jing-Yi Chen
IPC分类号： H01J1/62
CPC分类号： H01L33/486 , H01L25/0753 , H01L25/167 , H01L33/62 , H01L2924/0002 , H05B33/0821 , H01L2924/00
摘要： An LED base structure with an embedded capacitor includes a body, at least one pair of metal layers, at least one dielectric layer, and at least two conductive channels. The body is an insulating base. The metal layers are disposed in the body, and the dielectric layer is disposed between the metal layers, so as to form an embedded capacitor. The conductive channels are electrically connected to the metal layers, respectively. The LED base structure is further electrically connected to a resistor for forming a resistor-capacitor delay circuit whereby a phase delay is effectuated whenever AC power is supplied to the LED base structure, so as to control the time for switching on one of two parallel-connected LEDs and, as a result, prevent the LEDs from flashing which might otherwise arise when the LEDs are supplied with AC power.
摘要翻译：具有嵌入式电容器的LED基座结构包括主体，至少一对金属层，至少一个电介质层和至少两个导电沟道。身体是绝缘基座。金属层设置在主体中，并且电介质层设置在金属层之间，以便形成嵌入式电容器。导电通道分别电连接到金属层。 LED基座结构进一步电连接到用于形成电阻器 - 电容器延迟电路的电阻器，由此每当向LED基座结构提供AC电力时，实现相位延迟，以便控制用于切换两个并联 - 连接的LED，从而防止LED闪烁，否则当LED被提供交流电源时可能会发生。

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