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1. 发明专利

AU2020213494A1 Method for simulating CIE standard illuminant using multi-channel LEDs and illumination system 未知
公开(公告)号：AU2020213494A1
公开(公告)日：2021-08-12
申请号：AU2020213494
申请日：2020-01-13
申请人： JIN PENG
发明人： JIN PENG
IPC分类号： G01J3/50
摘要： Provided in the present invention are a method for simulating a CIE standard illuminant using multi-channel LEDs and an illumination system. The method relates to adjusting, according to chromaticity coordinates, brightness of a main light source control channel, a wavelength supplement control channel, and a color temperature adjustment control channel, so as to enable mixed chromaticity coordinates to reach chromaticity coordinates of a CIE standard illuminant to be simulated. According to the method, LED control channels are reduced by means of grouping optimization; and the use of a filter, a technique abandoned by multi-channel LEDs, achieves qualitative transitions that the number of control channels is greatly reduced and the simulation of a standard illuminant light source using multi-channel LEDs can be controlled by means of single chromaticity, without the need of chromaticity control by means of spectroscopic conversion. In a process of simulating a CIE standard illuminant using multi-channel LEDs, the light source performance of a pure chromaticity technique having lower analysis performance surpasses or reaches the light source performance achieved by a spectroscopic chromaticity technique having higher analysis performance.

2. 发明公开

EP3919877A1 METHOD FOR SIMULATING CIE STANDARD ILLUMINANT USING MULTI-CHANNEL LEDS AND ILLUMINATION SYSTEM 有权
公开(公告)号：EP3919877A1
公开(公告)日：2021-12-08
申请号：EP20749416.2
申请日：2020-01-13
申请人： Jin, Peng
发明人： Jin, Peng
IPC分类号： G01J3/50
摘要： A method and an illumination system for simulating a CIE standard illuminant with a multi-channel LED are disclosed. The method includes adjusting a brightness of the main light source control channel, the wavelength complementary control channel, the color temperature adjustment control channel to make a mixed chromaticity coordinate meet a chromaticity coordinate of the CIE standard illuminant to be simulated according to chromaticity coordinates. The LED control channels are reduced through group optimization, and a technology which is discarded by multi-channel LED such as a filter is used, a control of a light source substantially reducing number of control channels and enabling a multi-channel LED to simulate a standard illuminant is formed, such that a single chromaticity control rather than a chromaticity control which must be transformed by a spectral conversion is achieved.

3. 发明申请

WO2008073957A3 COMPOUNDS AND METHODS FOR MODULATING THE SILENCING OF A POLYNUCLEOTIDE OF INTEREST 审中-公开
公开(公告)号：WO2008073957A3
公开(公告)日：2008-06-19
申请号：PCT/US2007/087172
申请日：2007-12-12
申请人： EMORY UNIVERSITY , JIN, Peng
发明人： JIN, Peng
IPC分类号： A61K31/4375 , A61K31/47 , A61K31/4741 , A61K31/519 , A61K38/00 , A61P31/12 , A61P43/00
摘要： Methods and compositions comprising chemical compounds that modulate the silencing of a polynucleotide of interest in a cell are provided. Such chemical compounds when used in combination with an appropriate silencing element can be used to modulate (e.g., increase) the level of the polynucleotide targeted by the silencing element. Methods of using such compositions both in therapies involving RNAi -mediated suppression of gene expression, as well as, in vitro methods that allow for the targeted modulation of expression of a polynucleotide of interest are provided. Pharmaceutical or cosmetic compositions comprising such compounds and silencing elements also are disclosed. Methods for screening a compound of interest for the ability to modulate the activity of a heterologous silencing element also are provided.

4. 发明申请

WO2007050741A2 COMPOSITIONS FOR TREATING FRAGILE X AND OTHER DISORDERS METHODS OF USE THEREOF AND SCREENING FOR COMPOUNDS FOR FRAGILE X AND OTHER DISORDERS 审中-公开
标题翻译：用于治疗脆弱性X及其他疾病的组合物及其使用方法和筛选化合物X和其他疾病
公开(公告)号：WO2007050741A2
公开(公告)日：2007-05-03
申请号：PCT/US2006041759
申请日：2006-10-26
申请人： UNIV EMORY , WARREN STEPHEN T , CHANG SHUANG , JIN PENG
发明人： WARREN STEPHEN T , CHANG SHUANG , JIN PENG
IPC分类号： C40B50/06 , C40B40/10
CPC分类号： A61K31/4462 , A61K31/4178 , G01N33/5085 , G01N2800/28
摘要： Methods of screening compounds, active compositions, pharmaceutical compositions, methods of treating disorders, methods of preventing disorders, and kits to screen a librar of com ounds are disclosed.
摘要翻译：公开了筛选化合物，活性组合物，药物组合物，治疗障碍的方法，预防病症的方法和筛选化合物的图书馆的试剂盒的方法。

5. 发明申请

WO2008073961A3 COMPOUNDS AND METHODS FOR MODULATING THE SILENCING OF A POLYNUCLEOTIDE OF INTEREST 审中-公开
公开(公告)号：WO2008073961A3
公开(公告)日：2008-06-19
申请号：PCT/US2007/087186
申请日：2007-12-12
申请人： EMORY UNIVERSITY , JIN, Peng
发明人： JIN, Peng
IPC分类号： A61K31/4439 , A61P31/12 , A61P43/00
摘要： Methods and compositions comprising chemical compounds that modulate the silencing of a polynucleotide of interest in a cell are provided. Such chemical compounds when used in combination with an appropriate silencing element can be used to modulate (increase or decrease) the level of the polynucleotide targeted by the silencing element. Methods of using such compositions both in therapies involving RNAi-mediated suppression of gene expression, as well as, in vitro methods that allow for the targeted modulation of expression of a polynucleotide of interest are provided. Pharmaceutical or cosmetic compositions comprising such compounds and silencing elements also are disclosed. Methods for screening a compound of interest for the ability to modulate the activity of a heterologous silencing element also are provided.

6. 发明申请

WO2005057289A1 IMPROVED LITHOGRAPHIC PROCESS 审中-公开
标题翻译：改进的光刻过程
公开(公告)号：WO2005057289A1
公开(公告)日：2005-06-23
申请号：PCT/GB2004/005048
申请日：2004-12-01
申请人： THE UNIVERSITY OF BIRMINGHAM , JIANG, Kyle , JIN, Peng
发明人： JIANG, Kyle , JIN, Peng
IPC分类号： G03F7/20
CPC分类号： G03F7/2008 , G03F7/20
摘要： The present invention provides a lithographic process for producing high aspect ratio parts from an epoxy-type negative photoresist comprising the steps of: (i) irradiating a prebaked masked epoxy-type negative photoresist on a substrate with light at a total energy density of from 18,000 to 35,000mJ/cm 2 , (ii) post-baking the exposed photoresist at elevated temperature, and (iii) developing the exposed photoresist in a solvent, wherein no more than 15 % of the energy density is contributed by light having a wavelength of 400nm or less. The invention also discloses a reciprocating microengine (10) comprising a cylinder (14), piston (12) and crankshaft made by the process.
摘要翻译：本发明提供了一种用于从环氧型负型光致抗蚀剂制造高纵横比部件的光刻工艺，其特征在于包括以下步骤：（i）在总能量密度为18,000的光照射基底上的预焙掩膜的环氧型负性光致抗蚀剂至35,000mJ / cm 2，（ii）在升高的温度下对曝光的光致抗蚀剂进行后烘烤，和（iii）在溶剂中显影曝光的光致抗蚀剂，其中不超过15％的能量密度由具有波长400nm以下。本发明还公开了一种往复式微发动机（10），其包括由该过程制成的气缸（14），活塞（12）和曲轴。

7. 发明申请

WO2008073957A8 COMPOUNDS AND METHODS FOR MODULATING THE SILENCING OF A POLYNUCLEOTIDE OF INTEREST 审中-公开
标题翻译：用于调节多焦点的沉降的化合物和方法
公开(公告)号：WO2008073957A8
公开(公告)日：2009-07-30
申请号：PCT/US2007087172
申请日：2007-12-12
申请人： UNIV EMORY , JIN PENG
发明人： JIN PENG
IPC分类号： A61K31/4375 , A61K31/47 , A61K31/4741 , A61K31/519 , A61K38/00 , A61P31/12 , A61P43/00
CPC分类号： C12N15/111 , A61K31/4375 , A61K31/47 , A61K31/4741 , A61K31/519 , A61K31/7088 , C12N2310/14 , C12N2310/141 , C12N2320/50 , A61K2300/00
摘要： Methods and compositions comprising chemical compounds that modulate the silencing of a polynucleotide of interest in a cell are provided. Such chemical compounds when used in combination with an appropriate silencing element can be used to modulate (e.g., increase) the level of the polynucleotide targeted by the silencing element. Methods of using such compositions both in therapies involving RNAi -mediated suppression of gene expression, as well as, in vitro methods that allow for the targeted modulation of expression of a polynucleotide of interest are provided. Pharmaceutical or cosmetic compositions comprising such compounds and silencing elements also are disclosed. Methods for screening a compound of interest for the ability to modulate the activity of a heterologous silencing element also are provided.
摘要翻译：提供了包含调节细胞中目的多核苷酸沉默的化合物的方法和组合物。当与适当的沉默元件组合使用时，这种化合物可用于调节（例如，增加）沉默元件靶向的多核苷酸的水平。提供了在涉及RNAi介导的基因表达抑制的治疗中使用这些组合物的方法，以及允许目的调节感兴趣的多核苷酸表达的体外方法。还公开了包含这些化合物和沉默元件的药物或化妆品组合物。还提供了筛选感兴趣的化合物调节异源沉默元件的活性能力的方法。

8. 发明申请

WO2008073957A2 COMPOUNDS AND METHODS FOR MODULATING THE SILENCING OF A POLYNUCLEOTIDE OF INTEREST 审中-公开
标题翻译：用于调节感兴趣的多核苷酸沉默的化合物和方法
公开(公告)号：WO2008073957A2
公开(公告)日：2008-06-19
申请号：PCT/US2007087172
申请日：2007-12-12
申请人： UNIV EMORY , JIN PENG
发明人： JIN PENG
CPC分类号： C12N15/111 , A61K31/4375 , A61K31/47 , A61K31/4741 , A61K31/519 , A61K31/7088 , C12N2310/14 , C12N2310/141 , C12N2320/50 , A61K2300/00
摘要： Methods and compositions comprising chemical compounds that modulate the silencing of a polynucleotide of interest in a cell are provided. Such chemical compounds when used in combination with an appropriate silencing element can be used to modulate (e.g., increase) the level of the polynucleotide targeted by the silencing element. Methods of using such compositions both in therapies involving RNAi -mediated suppression of gene expression, as well as, in vitro methods that allow for the targeted modulation of expression of a polynucleotide of interest are provided. Pharmaceutical or cosmetic compositions comprising such compounds and silencing elements also are disclosed. Methods for screening a compound of interest for the ability to modulate the activity of a heterologous silencing element also are provided.
摘要翻译：提供了包含调节细胞中感兴趣多核苷酸沉默的化学化合物的方法和组合物。当与合适的沉默元件组合使用时，这些化学化合物可用于调节（例如增加）沉默元件靶向的多核苷酸的水平。提供了在涉及RNAi介导的基因表达抑制的疗法中使用这种组合物的方法，以及允许针对性地调节目的多核苷酸表达的体外方法。也公开了包含这些化合物和沉默元件的药物或美容组合物。还提供了用于筛选感兴趣的化合物以调节异源沉默元件的活性的能力的方法。

9. 发明申请

WO03041659A3 METHOD AND IDENTIFICATION OF DOWNSTREAM MRNA LIGANDS TO FMRP AND THEIR ROLE IN FRAGILE X SYNDROME AND ASSOCIATED DISORDERS 审中-公开
标题翻译：下颌骨MRNA配体对FMRP的方法和鉴定及其在脆性X综合征和相关疾病中的作用
公开(公告)号：WO03041659A3
公开(公告)日：2003-07-31
申请号：PCT/US0236861
申请日：2002-11-15
申请人： UNIV EMORY , UNIV DUKE , UNIV ROCKEFELLER , WARREN STEPHEN T , BROWN-KENNERLY VICTORIA , JIN PENG , CEMAN STEPHANIE , DARNELL ROBERT B , DARNELL JENNIFER C , KEENE JACK D , TENENBAUM SCOTT A
发明人： WARREN STEPHEN T , BROWN-KENNERLY VICTORIA , JIN PENG , CEMAN STEPHANIE , DARNELL ROBERT B , DARNELL JENNIFER C , KEENE JACK D , TENENBAUM SCOTT A
IPC分类号： A01K67/027 , C07H21/04 , C07K14/705 , C07K16/28 , C12Q1/68 , A61K48/00 , C12P19/34
CPC分类号： C12Q1/6883 , C12Q1/6837 , C12Q2600/158
摘要： Compositions and methods for identifying and/or modulating RNA transcripts and/or genes involved in fragile X syndrome and other associated disorders are provided. In particular, RNA targets for fragile X mental retardation protein (FMRP) have been identified by a novel monoclonal antibody to FMRP and a consensus sequence for the RNA binding region has been identified. Arrays for identifying compounds, proteins, nucleotides, and the like that modulate the RNA targets or associated genes are provided. Additionally, methods for modulating RNA targets are provided.
摘要翻译：提供了用于鉴定和/或调节涉及脆性X综合征和其它相关病症的RNA转录物和/或基因的组合物和方法。特别地，已经通过FMRP的新型单克隆抗体鉴定了脆性X智力迟钝蛋白（FMRP）的RNA靶标，并且已经鉴定了RNA结合区域的共有序列。提供了用于鉴定调节RNA靶标或相关基因的化合物，蛋白质，核苷酸等的阵列。另外，提供了调节RNA靶标的方法。

10. 发明申请

WO2008073961A8 COMPOUNDS AND METHODS FOR MODULATING THE SILENCING OF A POLYNUCLEOTIDE OF INTEREST 审中-公开
标题翻译：用于调节多焦点的沉降的化合物和方法
公开(公告)号：WO2008073961A8
公开(公告)日：2009-08-06
申请号：PCT/US2007087186
申请日：2007-12-12
申请人： UNIV EMORY , JIN PENG
发明人： JIN PENG
IPC分类号： A61K31/4439 , A61P31/12 , A61P43/00
CPC分类号： A61K31/4439
摘要： Methods and compositions comprising chemical compounds that modulate the silencing of a polynucleotide of interest in a cell are provided. Such chemical compounds when used in combination with an appropriate silencing element can be used to modulate (increase or decrease) the level of the polynucleotide targeted by the silencing element. Methods of using such compositions both in therapies involving RNAi-mediated suppression of gene expression, as well as, in vitro methods that allow for the targeted modulation of expression of a polynucleotide of interest are provided. Pharmaceutical or cosmetic compositions comprising such compounds and silencing elements also are disclosed. Methods for screening a compound of interest for the ability to modulate the activity of a heterologous silencing element also are provided.
摘要翻译：提供了包含调节细胞中目的多核苷酸沉默的化合物的方法和组合物。当与适当的沉默元件组合使用时，这种化合物可用于调节（增加或减少）沉默元件靶向的多核苷酸的水平。提供了在涉及RNAi介导的基因表达抑制的治疗中使用这些组合物的方法，以及允许针对目的调节感兴趣的多核苷酸表达的体外方法。还公开了包含这些化合物和沉默元件的药物或化妆品组合物。还提供了筛选感兴趣的化合物调节异源沉默元件的活性能力的方法。

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