专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2007048831A3 BIODEGRADABLE SCAFFOLD WITH ECM MATERIAL 审中-公开
标题翻译：采用ECM材料的可生物降解脚手架
公开(公告)号：WO2007048831A3
公开(公告)日：2007-06-28
申请号：PCT/EP2006067837
申请日：2006-10-26
申请人： COLOPLAST AS , NIELSEN PETER SYLVEST , NIELSEN BRIAN , JESPERSEN LENE KARIN , EVERLAND HANNE , NIELSEN LENE FELDSKOV
发明人： NIELSEN PETER SYLVEST , NIELSEN BRIAN , JESPERSEN LENE KARIN , EVERLAND HANNE , NIELSEN LENE FELDSKOV
IPC分类号： A61L15/00
CPC分类号： A61L27/3633 , A61L27/56 , A61L27/58
摘要： We add discontinuous regions of Extra Cellular Matrix (ECM) to a biodegradable scaffold. Hereby it is possible to combine the range of physical properties the scaffold can offer with the reconstructive properties of the ECM. The optimal amount of discrete ECM material for each application is disclosed and this concentration is equally distributed in the dressing hence avoiding unnecessary high concentrations of ECM. In addition to the effect of the ECM, the porous structure of the base material provides the cells with a structure for in-growth.
摘要翻译：我们将额外细胞基质（ECM）的不连续区域添加到可生物降解的支架中。因此，可以将支架可提供的物理性质的范围与ECM的重建特性相结合。公开了每种应用的离散ECM材料的最佳量，并且该浓度在敷料中均匀分布，因此避免了不必要的高浓度ECM。除了ECM的作用之外，基材的多孔结构还为电池提供内生长结构。

2. 发明申请

WO2005094875A1 USE OF EPI-HNE 1-4 审中-公开
标题翻译： EPI-HNE的使用1-4
公开(公告)号：WO2005094875A1
公开(公告)日：2005-10-13
申请号：PCT/DK2005/000216
申请日：2005-03-30
申请人： COLOPLAST A/S , JENSEN, Flemming, Reissig , JESPERSEN, Lene, Karin , LAUEMOELLER, Sanne, Lise , LARSEN, Kristian , BOUGHERARA, Chaabane
发明人： JENSEN, Flemming, Reissig , JESPERSEN, Lene, Karin , LAUEMOELLER, Sanne, Lise , LARSEN, Kristian , BOUGHERARA, Chaabane
IPC分类号： A61K38/57
CPC分类号： A61K38/57 , C07K14/8114
摘要： The invention relates to use of at least one of the compounds EPI-HNE 1, EPI-HNE 2, EPI-HNE 3 or EPI-HNE 4 for manufacture of a medicament for treatment of chronic wounds or burns. The EPI-HNE 1-4 compounds are e.g. suitable for incorporation into a wound care device, such as a dressing.
摘要翻译：本发明涉及至少一种化合物EPI-HNE 1，EPI-HNE 2，EPI-HNE 3或EPI-HNE 4的用途，用于制备用于治疗慢性伤口或烧伤的药物。 EPI-HNE 1-4化合物是例如适合并入伤口护理装置，如敷料。

3. 发明申请

WO2007101443A8 DEGRADABLE HYDROPHILIC BLOCK COPOLYMERS WITH IMPROVED BIOCOMPATIBILITY FOR SOFT TISSUE REGENERATION 审中-公开
标题翻译：具有改善软组织再生的生物活性的可降解的亲水性嵌段共聚物
公开(公告)号：WO2007101443A8
公开(公告)日：2007-11-08
申请号：PCT/DK2007000115
申请日：2007-03-07
申请人： COLOPLAST AS , VANGE JAKOB , SCHWACH-ABDELLAOUI KHADIJA , EVERLAND HANNE , NIELSEN PETER SYLVEST , NIELSEN BRIAN , JESPERSEN LENE KARIN , NIELSEN LENE FELDSKOV
发明人： VANGE JAKOB , SCHWACH-ABDELLAOUI KHADIJA , EVERLAND HANNE , NIELSEN PETER SYLVEST , NIELSEN BRIAN , JESPERSEN LENE KARIN , NIELSEN LENE FELDSKOV
IPC分类号： C08G63/664 , A61L15/26 , A61L27/18 , A61L27/56 , C08G81/00 , C08J9/00 , C08J9/28
CPC分类号： C08G63/664 , A61L15/26 , A61L15/425 , A61L27/18 , A61L27/56 , C08G2261/126 , C08J9/28 , C08J2201/0482 , C08J2201/0484 , C08J2367/04 , C12N5/0068 , C12N2533/30 , C12N2533/40 , Y10T428/249958 , C08L67/04
摘要： The present application discloses biodegradable polymers, to porous and other materials comprising such polymers, and to various medical uses of such materials, including use as a scaffold for supporting cell adhesion or the in-growth for regeneration of tissue. The polymer is of the formula A-O-(CHR 1 CHR 2 O) n -B wherein A is a poly(lactide-co-glycolide) residue, the molar ratio of (i) lactide units [-CH(CH 3 )-COO-] and (ii) glycolide units [-CH 2 -COO-] in the poly(lactide-co-glycolide) residue being in the range of 80:20 to 10:90, B is either a poly(lactide-co-glycolide) residue or hydrogen, C 1-6 -alkyl or hydroxy protecting groups, one of R 1 and R 2 is hydrogen or methyl, and the other is hydrogen, n is 10-1000, the molar ratio of (iii) polyalkylene glycol units [-(CHR 1 CHR 2 O)-] to the combined amount of (i) lactide units and (ii) glycolide units in the poly(lactide-co-glycolide) residue(s) is at the most 14:86, and the molecular weight of the copolymer is at least 20,000 g/mol.
摘要翻译：本申请公开了可生物降解的聚合物，包括这种聚合物的多孔和其它材料，以及这些材料的各种医学用途，包括用作支撑细胞粘附的支架或用于组织再生的生长。该聚合物具有下式：其中A是聚（丙交酯 - 共 - 乙交酯），其中A是聚（丙交酯 - 共 - 乙交酯））残基，（i）丙交酯单元[-CH（CH 3） - COO-]的摩尔比和（ii）乙交酯单元[-CH 2 -COO- ]在聚（丙交酯 - 共 - 乙交酯）残基中的比例在80:20至10:90的范围内，B是聚（丙交酯 - 共 - 乙交酯）残基或氢，C 1-6 - N 1 - 烷基或羟基保护基，R 1和R 2之一是氢或甲基，另一个是氢，n是10-1000，摩尔比的（iii）聚亚烷基二醇单元[ - （CHR 1 CH 2 O） - ]与（i）丙交酯单元和（ii）乙二醇单元的组合聚（丙交酯 - 共 - 乙交酯）残基最多为14:86，共聚物的分子量至少为20,000g / mol。

4. 发明申请

WO2008074331A1 WOUND OR TISSUE DRESSING COMPRISING LACTIC ACID BACTERIA 审中-公开
标题翻译：包裹酸乳杆菌的组织或组织
公开(公告)号：WO2008074331A1
公开(公告)日：2008-06-26
申请号：PCT/DK2007/050196
申请日：2007-12-19
申请人： Ferrosan A/S , HANSEN, John E. , JESPERSEN, Lene Karin
发明人： HANSEN, John E. , JESPERSEN, Lene Karin
IPC分类号： A61L15/32 , A61L15/36
CPC分类号： A61L15/36
摘要： The present invention is directed to a wound or tissue dressing comprising a bacteria having the property of producing lactic acid from sugars by fermentation of the sugars. The bacteria preferably belongs to the family of lactic acid bacteria. The family of lactic acid bacteria refers to any bacteria belonging to a genus selected from the group consisting of Carnobacterium, Enterococcus, Lactobacillus, Lactococcus, Leuconostoc, Oenococcus, Pediococcus, Streptococcus, Tetragenococcus, Vagococcus and Weissella. There is also provided a wound or tissue dressing comprising an absorbent compound for absorbing wound exudate, wherein said wound or tissue dressing is attached to or comprises a lactic acid bacterium. The utility of the present invention is demonstrated by use of the wound or tissue dressings in methods for treating a wound or damaged tissue in an individual, said method comprising the steps of contacting said wound or damaged tissue with the wound or tissue dressing according to the invention, thereby treating the wound or damaged tissue. The treatment results in healing of the wound or in accelerated healing of the wound. There is also provided the use of a lactic acid bacteria in the manufacture of a wound or tissue dressing for treating or accelerating the healing of a wound in an individual.
摘要翻译：本发明涉及一种包含细菌的伤口或组织敷料，其具有通过发酵糖从糖生产乳酸的性质。细菌优选属于乳酸菌家族。乳酸菌系指属于选自Carnobacterium，Enterococcus，Lactobacillus，Lactococcus，Leuconostoc，Oenococcus，Pediococcus，Streptococcus，Tetragenococcus，Vagococcus和Weissella的属的任何细菌。还提供了包含用于吸收伤口渗出物的吸收剂化合物的伤口或组织敷料，其中所述伤口或组织敷料附着或包含乳酸菌。本发明的用途通过在伤口或组织敷料中用于治疗个体中的伤口或受损组织的方法中被使用来证明，所述方法包括以下步骤：使伤口或受损组织与伤口或组织敷料接触，根据从而治疗伤口或损伤的组织。该治疗导致伤口愈合或加速伤口愈合。还提供了在制造伤口或组织敷料中的乳酸菌用于治疗或加速个体伤口愈合的用途。

5. 发明申请

WO2007101443A1 DEGRADABLE HYDROPHILIC BLOCK COPOLYMERS WITH IMPROVED BIOCOM PATIBILΠ FOR SOFT TISSUE REGENERATION 审中-公开
标题翻译：具有改进的生物体肥料的可降解的亲水性嵌段共聚物？用于软组织再生
公开(公告)号：WO2007101443A1
公开(公告)日：2007-09-13
申请号：PCT/DK2007/000115
申请日：2007-03-07
申请人： COLOPLAST A/S , VANGE, Jakob , SCHWACH-ABDELLAOUI, Khadija , EVERLAND, Hanne , NIELSEN, Peter, Sylvest , NIELSEN, Brian , JESPERSEN, Lene, Karin , NIELSEN, Lene, Feldskov
发明人： VANGE, Jakob , SCHWACH-ABDELLAOUI, Khadija , EVERLAND, Hanne , NIELSEN, Peter, Sylvest , NIELSEN, Brian , JESPERSEN, Lene, Karin , NIELSEN, Lene, Feldskov
IPC分类号： C08G63/664 , C08G81/00 , C08J9/00 , C08J9/28 , A61L27/18 , A61L15/26 , A61L27/56
CPC分类号： C08G63/664 , A61L15/26 , A61L15/425 , A61L27/18 , A61L27/56 , C08G2261/126 , C08J9/28 , C08J2201/0482 , C08J2201/0484 , C08J2367/04 , C12N5/0068 , C12N2533/30 , C12N2533/40 , Y10T428/249958 , C08L67/04
摘要： The present application discloses biodegradable polymers, to porous and other materials comprising such polymers, and to various medical uses of such materials, including use as a scaffold for supporting cell adhesion or the in-growth for regeneration of tissue. The polymer is of the formula A-O-(CHR 1 CHR 2 O) n -B wherein A is a poly(lactide-co-glycolide) residue, the molar ratio of (i) lactide units [-CH(CH 3 )-COO-] and (ii) glycolide units [-CH 2 -COO-] in the poly(lactide-co-glycolide) residue being in the range of 80:20 to 10:90, B is either a poly(lactide-co-glycolide) residue or hydrogen, C 1-6 -alkyl or hydroxy protecting groups, one of R 1 and R 2 is hydrogen or methyl, and the other is hydrogen, n is 10-1000, the molar ratio of (iii) polyalkylene glycol units [-(CHR 1 CHR 2 O)-] to the combined amount of (i) lactide units and (ii) glycolide units in the poly(lactide-co-glycolide) residue(s) is at the most 14:86, and the molecular weight of the copolymer is at least 20,000 g/mol.
摘要翻译：本申请公开了可生物降解的聚合物，包括这种聚合物的多孔和其它材料，以及这种材料的各种医学用途，包括用作支撑细胞粘附的支架或用于组织再生的生长中的用途。该聚合物具有下式：其中A是聚（丙交酯 - 共 - 乙交酯），其中A是聚（丙交酯 - 共 - 乙交酯））残基，（i）丙交酯单元[-CH（CH 3） - COO-]的摩尔比和（ii）乙交酯单元[-CH 2 -COO- ]在聚（丙交酯 - 共 - 乙交酯）残基中的比例在80:20至10:90的范围内，B是聚（丙交酯 - 共 - 乙交酯）残基或氢，C 1-6 - N 1 - 烷基或羟基保护基，R 1和R 2之一是氢或甲基，另一个是氢，n是10-1000，摩尔比的（iii）聚亚烷基二醇单元[ - （CHR 1 CH 2 O） - ]与（i）丙交酯单元和（ii）乙二醇单元的组合聚（丙交酯 - 共 - 乙交酯）残基最多为14:86，共聚物的分子量至少为20,000g / mol。

6. 发明申请

WO2007048831A2 BIODEGRADABLE SCAFFOLD WITH ECM MATERIAL 审中-公开
标题翻译：具有ECM材料的生物可降解SCAFFOLD
公开(公告)号：WO2007048831A2
公开(公告)日：2007-05-03
申请号：PCT/EP2006/067837
申请日：2006-10-26
申请人： COLOPLAST A/S , NIELSEN, Peter Sylvest , NIELSEN, Brian , JESPERSEN, Lene Karin , EVERLAND, Hanne , NIELSEN, Lene Feldskov
发明人： NIELSEN, Peter Sylvest , NIELSEN, Brian , JESPERSEN, Lene Karin , EVERLAND, Hanne , NIELSEN, Lene Feldskov
IPC分类号： A61L15/00
CPC分类号： A61L27/3633 , A61L27/56 , A61L27/58
摘要： We add discontinuous regions of Extra Cellular Matrix (ECM) to a biodegradable scaffold. Hereby it is possible to combine the range of physical properties the scaffold can offer with the reconstructive properties of the ECM. The optimal amount of discrete ECM material for each application is disclosed and this concentration is equally distributed in the dressing hence avoiding unnecessary high concentrations of ECM. In addition to the effect of the ECM, the porous structure of the base material provides the cells with a structure for in-growth.
摘要翻译：我们将Extra Cellular Matrix（ECM）的不连续区域添加到可生物降解的支架中。因此，可以组合脚手架可以提供的物理范围与ECM的重建性质。公开了每种应用的离散ECM材料的最佳量，并且该浓度均匀分布在敷料中，从而避免不必要的高浓度的ECM。除了ECM的作用之外，基体材料的多孔结构为细胞提供了用于生长的结构。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式