专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20220096806A1 A MICRONEEDLE DEVICE AND A MICRONEEDLE DEVICE FOR USE IN A METHOD FOR THE TREATMENT OF A LUMEN, VESSEL, CAVITY OR A FISTULA 有权
公开(公告)号：US20220096806A1
公开(公告)日：2022-03-31
申请号：US17422030
申请日：2020-01-29
申请人： JANISYS LIMITED
发明人： John O'DEA
IPC分类号： A61M37/00
摘要： A microneedle device for delivering a therapeutic fluid to a fistula comprises a carrier element (5) formed by a pair of shells (9). The shells (9) are of semi-circular cross-section and are urged together by resilient bands (10) to define a main bore (14) extending therethrough. A plurality of microneedles (17) extend from the respective shells (9). An operating member (30) of circular transverse cross-section of external diameter greater than the diameter of the main bore (14) is urgeable into the main bore (14) for urging the shells (9) and in turn the microneedles (17) radially outwardly from a rest state to an engagement state, and into the tissue within the fistula (3). A tubular shield (23) of circular transverse cross-section having a carrier element accommodating bore (25) extending therethrough is provided for accommodating the carrier element (3) with the microneedles (17) in the rest state for facilitating insertion of the carrier element (3) located within the tubular shield (24) into the fistula (3) in order to avoid engagement of the microneedles (17) with the tissue of the fistula (3) during insertion of the carrier element (5). On the carrier element (5) being correctly located in the fistula (3), the tubular shield (24) is withdrawn and the operating member (30) is urged into the main bore (14) of the carrier element (5) for urging the microneedles (17) into engagement with the tissue. Main chambers (40) communicate with the microneedles (17) through communicating ports (45) and corresponding inlet ports (21) when the operating member (30) is aligned in the carrier element (5). A delivery needle is urgeable sequentially into the main chambers (40) for delivering the therapeutic fluid into the main chambers (40) for in turn delivery through the microneedles (17).

2. 发明申请

WO2009069112A1 A DELIVERY DEVICE FOR ADMINISTERING AN ACTIVE SUBSTANCE TO A SUBJECT 审中-公开
标题翻译：用于管理主体的主体的输送装置
公开(公告)号：WO2009069112A1
公开(公告)日：2009-06-04
申请号：PCT/IE2008/000115
申请日：2008-11-28
申请人： JANISYS LIMITED , O'DEA, John , BAMBURY, Eoin
发明人： O'DEA, John , BAMBURY, Eoin
IPC分类号： A61M37/00 , A61M31/00 , A61K9/00
CPC分类号： A61M5/2046 , A61K9/0021 , A61K9/0024 , A61K9/0097 , A61M37/0015 , A61M37/0069 , A61M2037/0023 , A61M2037/0046 , A61M2205/0244
摘要： A delivery device (1) for administering an active substance to a subject transdermal^ comprises a first plate member (7) having a plurality of first chambers (8) formed therein. Solid form structures (2) comprising the active substance and of conical shape having a pointed skin penetrating tip (5) are located in the first chambers (8). A second plate member (12) having a plurality of second chambers (16) comprising a driving substance (18) is secured to the first plate member (7) with a first membrane (20) of an expandable material sealably located between the respective first and second plate members (7,12). Expansion of the driving substance (18) in the second chambers (22) urges the first membrane (20) into the corresponding first chambers (8) for in turn urging the solid form structures (2) to penetrate through a second membrane (22) into the skin of the subject. A third plate member (24) comprises a plurality of electrically powered heating elements (28) aligned with the second chambers (22) for heating the driving substance (18) in the second chambers (16) for in turn expanding the driving substances (18) therein.
摘要翻译：用于向受试者透皮施用活性物质的递送装置（1）包括具有形成在其中的多个第一室（8）的第一板构件（7）。包含活性物质和具有尖锐皮肤渗透尖端（5）的圆锥形状的固体形式结构（2）位于第一腔室（8）中。具有包括驱动物质（18）的多个第二腔室（16）的第二板构件（12）通过可膨胀材料的第一膜（20）固定到第一板构件（7），所述第一膜（20）可密封地位于相应的第一和第二板构件（7,12）。驱动物质（18）在第二腔室（22）中的膨胀将第一膜（20）推到相应的第一腔室（8）中，从而推动固体形式结构（2）穿透第二隔膜（22）进入主体的皮肤。第三板构件（24）包括与第二室（22）对准的多个电动加热元件（28），用于加热第二室（16）中的驱动物质（18），从而使驱动物质（18 ）。

3. 发明申请

WO2010052692A1 A TRANSFER DEVICE FOR TRANSFERRING A SUBSTANCE BETWEEN THE DEVICE AND A SUBJECT 审中-公开
标题翻译：用于传送设备和主体之间的物质的传送设备
公开(公告)号：WO2010052692A1
公开(公告)日：2010-05-14
申请号：PCT/IE2009/000076
申请日：2009-11-04
申请人： JANISYS LIMITED , O'DEA, John , BAMBURY, Eoin
发明人： O'DEA, John , BAMBURY, Eoin
IPC分类号： A61M37/00 , A61K9/00 , A61B10/00
CPC分类号： A61M37/0015 , A61B17/205 , A61B2010/008 , A61M2037/0023 , A61M2037/003 , A61M2037/0038 , A61M2037/0053 , A61M2037/0061
摘要： A micro-needle delivery device (1) comprises an active substance accommodating layer (17) having active substance accommodating chambers (20) therein, a drive substance accommodating layer (32) having drive substance accommodating chambers (35) therein aligned with the active substance accommodating chambers (20), an activating layer (45) having heating elements (48) aligned with the drive substance accommodating chambers (35) for heating a drive substance therein, and a micro-needle element (8) having a needle support layer (9) and a plurality of micro-needles (12) extending therefrom. A burstable first membrane (22) is located between and sealably secured to the micro-needle element (8) and to the active substance accommodating layer (17) for sealably closing the active substance accommodating chambers (20) at one end. A second stretchable membrane (30) is located between and sealably secured to the drive substance accommodating layer (32) and to the active substance accommodating layer (17) sealably closes the active substance accommodating chambers (20) at the other end, and the drive substance accommodating chambers (35). A third membrane (40) sealably closes the drive substance accommodating chambers (35).
摘要翻译：微针输送装置（1）包括其中具有活性物质容纳室（20）的活性物质容纳层（17），具有与活性物质对准的驱动物质容纳室（35）的驱动物质容纳层（32）容纳室（20），具有与用于加热其中的驱动物质的驱动物质容纳室（35）对准的加热元件（48）的活化层（45）和具有针支撑层的微针元件（8） 9）和从其延伸的多个微针（12）。可爆破的第一膜（22）位于微针元件（8）之间并且可密封地固定到活动物质容纳层（17）上，用于在一端密封地封闭活性物质容纳室（20）。第二可拉伸膜（30）位于驱动物质容纳层（32）之间并且可密封地固定在驱动物质容纳层（32）上并且活性物质容纳层（17）在另一端密封地封闭活性物质容纳室（20）物质容纳室（35）。第三膜（40）密封地封闭驱动物质容纳室（35）。

4. 发明申请

WO2010070628A1 A FLUID TRANSFER DEVICE AND AN ACTIVE SUBSTANCE CARTRIDGE FOR THE FLUID TRANSFER DEVICE, AND A METHOD FOR CONTROLLING THE PRESSURE AT WHICH AN ACTIVE SUBSTANCE IS DELIVERED TO A SUBJECT FROM A FLUID TRANSFER DEVICE 审中-公开
标题翻译：流体传输装置和用于流体传输装置的活性物质盒，以及用于控制活性物质被输送到流体传输装置的主体的压力的方法
公开(公告)号：WO2010070628A1
公开(公告)日：2010-06-24
申请号：PCT/IE2009/000092
申请日：2009-12-21
申请人： JANISYS LIMITED , O'DEA, John , BAMBURY, Eoin
发明人： O'DEA, John , BAMBURY, Eoin
IPC分类号： A61M37/00
CPC分类号： A61M37/0015 , A61M5/282 , A61M5/425 , A61M2005/14252 , A61M2037/0023 , A61M2037/003 , A61M2037/0061
摘要： A micro-needle device comprising an active substance layer (3) having a plurality of active substance chambers (4) formed therein, a drive substance layer (9) having a plurality of drive substance chambers (10) formed therein and a needle support layer (5) having a plurality of micro-needles (6) extending therefrom. An activation layer (12) comprising a plurality of heating elements (14) for heating an expandable drive substance (11) located in the drive substance chambers (10) for in turn urging the second membrane (16) into the active substance chamber (4) for pressurising and urging an active substance (2) therefrom through the corresponding micro-needle (6). A plurality of membrane accommodating recesses (25) extend into the needle support layer (5) for accommodating the first membrane (15) as the active substance in the corresponding active substance chamber (10) is pressurised. A puncturing member (33) with a piercing point (35) extends into each membrane accommodating recess (25). A barrier grating (41) extends across each active substance chamber (4) for preventing contact between the second membrane (16) and the corresponding puncturing member (33).
摘要翻译：一种微针装置，包括具有形成在其中的多个活性物质室（4）的活性物质层（3），形成有多个驱动物质室（10）的驱动物质层（9）和针支撑层（5）具有从其延伸的多个微针（6）。一种激活层（12），包括多个用于加热位于所述驱动物质室（10）中的可膨胀驱动物质（11）的加热元件（14），从而将所述第二隔膜（16）推进所述活性物质室（4）），用于通过相应的微针（6）加压和推压活性物质（2）。随着相应的活性物质室（10）中的活性物质被加压，多个膜容纳凹部（25）延伸到针支撑层（5）中，用于容纳第一膜（15）。具有穿刺点（35）的穿刺构件（33）延伸到每个膜容纳凹部（25）中。屏障光栅（41）延伸穿过每个活性物质室（4），以防止第二膜（16）和相应的穿刺构件（33）之间的接触。

5. 发明申请

WO2008012788A1 A MICROFLUIDIC DEVICE FOR CONTROLLED MOVEMENT OF MATERIAL AND A METHOD FOR DELIVERING A MATERIAL FROM A MICROFLUIDIC DEVICE 审中-公开
标题翻译：用于控制材料运动的微流体装置和从微流体装置传送材料的方法
公开(公告)号：WO2008012788A1
公开(公告)日：2008-01-31
申请号：PCT/IE2007/000074
申请日：2007-07-30
申请人： JANISYS LIMITED , ZHANG, Sean, Xiao-An , BECK, Patricia, A. , NICKEL, Janice, H.
发明人： ZHANG, Sean, Xiao-An , BECK, Patricia, A. , NICKEL, Janice, H.
IPC分类号： B01L3/00
CPC分类号： B01L3/0268 , A61M5/14244 , A61M5/14586 , A61M5/14593 , A61M5/172 , A61M37/0015 , A61M2005/14252 , A61M2205/3653 , B01L2400/0442 , B01L2400/046 , B01L2400/0481 , Y10T117/102 , Y10T117/104 , Y10T137/85978
摘要： A microfluidic device (100) for controllably moving a material of interest (102) includes a holding cavity (108) configured to hold the material of interest (102) and at least one actuator (120) configured to induce an activation material (116) to expand or contract. Expansion of the activation material (116) decreases the size of the holding cavity (108) to cause the material of interest (102) to be released from the holding cavity (108) and contraction of the activation material (116) increases the size of the holding cavity (108) to cause the material of interest (102) to be received into the holding cavity (108). The at least one actuator (120) is operable at multiple levels between a zero induction level to a maximum induction level on the activation material (116) to thereby controllably expand or contract the holding cavity (108) to release or receive a specified volume of the material of interest (102).
摘要翻译：用于可控地移动感兴趣的材料（102）的微流体装置（100）包括构造成保持感兴趣的材料（102）的保持腔（108）和被配置为诱导活化材料（116）的至少一个致动器（120）扩大或收缩。激活材料（116）的膨胀减小了保持腔（108）的尺寸，以使感兴趣的材料（102）从保持腔（108）释放并且活化材料（116）的收缩增大了所述保持腔（108）将感兴趣的材料（102）接收到所述保持腔（108）中。所述至少一个致动器（120）可在致动材料（116）上的零感应电平与最大感应电平之间的多个水平处操作，从而可控地扩张或收缩保持腔（108）以释放或接收指定体积感兴趣的材料（102）。

6. 发明申请

WO2020157740A2 A MICRONEEDLE DEVICE AND A MICRONEEDLE DEVICE FOR USE IN A METHOD FOR THE TREATMENT OF A LUMEN, VESSEL, CAVITY OR A FISTULA 审中-公开
公开(公告)号：WO2020157740A2
公开(公告)日：2020-08-06
申请号：PCT/IE2020/000003
申请日：2020-01-29
申请人： JANISYS LIMITED
发明人： O'DEA, John
摘要： A microneedle device for delivering a therapeutic fluid to a fistula comprises a carrier element (5) formed by a pair of shells (9). The shells (9) are of semi-circular cross-section and are urged together by resilient bands (10) to define a main bore (14) extending therethrough. A plurality of microneedles (17) extend from the respective shells (9). An operating member (30) of circular transverse cross-section of external diameter greater than the diameter of the main bore (14) is urgeable into the main bore (14) for urging the shells (9) and in turn the microneedles (17) radially outwardly from a rest state to an engagement state, and into the tissue within the fistula (3). A tubular shield (23) of circular transverse cross-section having a carrier element accommodating bore (25) extending therethrough is provided for accommodating the carrier element (3) with the microneedles (17) in the rest state for facilitating insertion of the carrier element (3) located within the tubular shield (24) into the fistula (3) in order to avoid engagement of the microneedles (17) with the tissue of the fistula (3) during insertion of the carrier element (5). On the carrier element (5) being correctly located in the fistula (3), the tubular shield (24) is withdrawn and the operating member (30) is urged into the main bore (14) of the carrier element (5) for urging the microneedles (17) into engagement with the tissue. Main chambers (40) communicate with the microneedles (17) through communicating ports (45) and corresponding inlet ports (21) when the operating member (30) is aligned in the carrier element (5). A delivery needle is urgeable sequentially into the main chambers (40) for delivering the therapeutic fluid into the main chambers (40) for in turn delivery through the microneedles (17).

7. 发明申请

WO2010125551A3 A MICRO-NEEDLE DEVICE AND APPARATUS AND A METHOD FOR APPLYING A MICRO-NEEDLE ELEMENT TO A SITE ON THE SKIN OF A SUBJECT 审中-公开
公开(公告)号：WO2010125551A3
公开(公告)日：2010-11-04
申请号：PCT/IE2010/000032
申请日：2010-04-29
申请人： JANISYS LIMITED , O'DEA, JOHN, , BAMBURY, Eoin
发明人： O'DEA, JOHN, , BAMBURY, Eoin
IPC分类号： A61M37/00
摘要： A micro-needle device (3) comprises a micro-needle element (2) which is carried on a strap (14) and is securable around a limb of a subject by the strap (14) with the micro-needle element (2) located at a desired site. A pressure sensor (23) is located between the strap (14) and the micro-needle element (2) for detecting the pressure at which the micro-needle element (2) is urged into engagement with the skin of the subject. An adjustable clasp (18) secures the strap (14) and permits adjustment of the tension in the strap (14) for in turn adjusting the pressure with which the micro-needle element (2) is urged into engagement with the skin of the subject. An electronic control circuit located in a housing (26) mounted on the strap (14) monitors the pressure read by the pressure sensor (23) and operates three light emitting diodes (28,29,30) to indicate the pressures with which the micro-needle element (2) is urged into engagement with the skin of the subject, and also to indicate when the micro-needle element (2) is urged into engagement with the skin of the subject by the strap (14) with micro-needles (5) of the micro-needle element (2) penetrating the skin of the subject to a desired depth.

8. 发明授权

EP2046498B1 A MICROFLUIDIC DEVICE FOR CONTROLLED MOVEMENT OF MATERIAL AND A METHOD FOR DELIVERING A MATERIAL FROM A MICROFLUIDIC DEVICE 有权
标题翻译：微流体装置从微流体装置送料控制的资料处理和方法
公开(公告)号：EP2046498B1
公开(公告)日：2011-11-16
申请号：EP07789927.6
申请日：2007-07-30
申请人： Janisys Limited
发明人： ZHANG, Sean, Xiao-An , BECK, Patricia, A. , NICKEL, Janice, H.
IPC分类号： B01L3/00
CPC分类号： B01L3/0268 , A61M5/14244 , A61M5/14586 , A61M5/14593 , A61M5/172 , A61M37/0015 , A61M2005/14252 , A61M2205/3653 , B01L2400/0442 , B01L2400/046 , B01L2400/0481 , Y10T117/102 , Y10T117/104 , Y10T137/85978
摘要： A microfluidic device (100) for controllably moving a material of interest (102) includes a holding cavity (108) configured to hold the material of interest (102) and at least one actuator (120) configured to induce an activation material (116) to expand or contract. Expansion of the activation material (116) decreases the size of the holding cavity (108) to cause the material of interest (102) to be released from the holding cavity (108) and contraction of the activation material (116) increases the size of the holding cavity (108) to cause the material of interest (102) to be received into the holding cavity (108). The at least one actuator (120) is operable at multiple levels between a zero induction level to a maximum induction level on the activation material (116) to thereby controllably expand or contract the holding cavity (108) to release or receive a specified volume of the material of interest (102).

9. 发明授权

EP3328269B1 A METHOD AND APPARATUS FOR MONITORING THE DEGREE OF OPENING OF THE CERVIX PRIOR TO THE ONSET OF LABOUR 有权转让
公开(公告)号：EP3328269B1
公开(公告)日：2020-09-30
申请号：EP16757976.2
申请日：2016-08-02
申请人： Janisys Limited
发明人： O'DEA, John
IPC分类号： A61B5/00 , A61B5/107

10. 发明授权

EP2227286B1 A DELIVERY DEVICE FOR ADMINISTERING AN ACTIVE SUBSTANCE TO A SUBJECT 有权
标题翻译：供给装置中，给人一种活性物质的人
公开(公告)号：EP2227286B1
公开(公告)日：2017-04-19
申请号：EP08853959.8
申请日：2008-11-28
申请人： Janisys Limited
发明人： O'DEA, John , BAMBURY, Eoin
IPC分类号： A61M37/00 , A61M31/00 , A61K9/00 , A61M5/20
CPC分类号： A61M5/2046 , A61K9/0021 , A61K9/0024 , A61K9/0097 , A61M37/0015 , A61M37/0069 , A61M2037/0023 , A61M2037/0046 , A61M2205/0244

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式