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1. 发明专利

AU1598701A Tissue-engineered ligament 未知
公开(公告)号：AU1598701A
公开(公告)日：2001-06-06
申请号：AU1598701
申请日：2000-11-10
申请人： JAMES CHO HONG GOH , KWAN HO CHAN
发明人： GOH JAMES CHO HONG , CHAN KWAN-HO
IPC分类号： A61F2/08

2. 发明授权

US5758253A Sintered titanium-graphite composite and method of making 失效
标题翻译：烧结钛 - 石墨复合材料及其制备方法
公开(公告)号：US5758253A
公开(公告)日：1998-05-26
申请号：US726732
申请日：1996-10-07
申请人： Swee Hin Teoh , Rajendran Thampuran , James Cho Hong Goh , Winston Kar Heng Seah
发明人： Swee Hin Teoh , Rajendran Thampuran , James Cho Hong Goh , Winston Kar Heng Seah
IPC分类号： B22F1/00 , A61F2/00 , A61L27/06 , A61L27/08 , A61L27/56 , C22C1/05 , C22C1/10 , C22C14/00 , B22F3/12
CPC分类号： C22C1/055 , A61L27/06 , A61L27/08 , A61L27/56 , A61F2310/00023 , A61F2310/00161 , Y10S264/36
摘要： A process for producing sintered titanium-graphite having improved wear resistance and low frictional characteristics is described. The said process which produces titanium-graphite composites having a triphasic structure with controlled porosity and a graphite lubricating film, comprises sintering a mixture of titanium and graphite powders in which the percentage of graphite may vary from 4 to 8 percent at temperatures from about 800.degree. C. to 1600.degree. C., for about 1/2 to 2 hours, under a compaction pressure of 0.17 to 0.62 MPa. The composites have applications in biomedical engineering and other fields of engineering due to their biocompatibility, strength and improved wear resistance.
摘要翻译：描述了具有改进的耐磨性和低摩擦特性的生产烧结钛 - 石墨的方法。所述制备具有可控孔隙率的三相结构和石墨润滑膜的钛 - 石墨复合材料的方法包括烧结钛和石墨粉末的混合物，其中石墨的百分比可以在约800℃的温度下变化4至8％在约0.17至0.62MPa的压实压力下，对于约+ E，fra 1/2 + EE至2小时。由于复合材料具有生物相容性，强度和耐磨性，因此具有生物医学工程和其他工程领域的应用。

3. 发明授权

US06737053B1 Tissue-engineered ligament 失效
标题翻译：组织工程韧带
公开(公告)号：US06737053B1
公开(公告)日：2004-05-18
申请号：US09710435
申请日：2000-11-10
申请人： James Cho Hong Goh , Kwan-Ho Chan
发明人： James Cho Hong Goh , Kwan-Ho Chan
IPC分类号： C12N500
CPC分类号： A61F2/08
摘要： An apparatus and method for the reconstruction of a previously torn ligament using a tissue-engineered ligament. The tissue-engineered ligament includes a scaffold of biocompatible material having at least one layer and forming a sheet. The scaffold is placed in a cultured medium for seeding with fibrocyte forming cells. The seeded scaffold is then placed in an incubator to increase the number of cells. The seeded scaffold is then formed into a slender structure suitable for implantation. The method of making a tissue-engineered ligament includes forming a scaffold of biocompatible material having at least one layer forming a sheet. Next, the scaffold sheet is seeded with fibrocyte forming cells. The method further includes increasing the number of cells on the seeded scaffold and forming a slender structure suitable for implantation from the scaffold.
摘要翻译：使用组织工程化韧带重建以前撕裂的韧带的装置和方法。组织工程化韧带包括具有至少一层并形成片材的生物相容性材料的支架。将支架放置在培养的培养基中用于与成纤维细胞形成细胞接种。然后将接种的支架放置在培养箱中以增加细胞数量。接种的支架然后形成适合植入的细长结构。制备组织工程化韧带的方法包括形成具有至少一层形成片材的生物相容性材料的支架。接下来，将支架片接种成纤维细胞形成细胞。该方法还包括增加接种的支架上的细胞数量并形成适于从支架植入的细长结构。

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