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    • 1. 发明授权
    • Perpendicular magnetic recording media and methods for producing the same
    • 垂直磁记录介质及其制造方法
    • US09472227B2
    • 2016-10-18
    • US13166002
    • 2011-06-22
    • Hi ShinIwao Okamoto
    • Hi ShinIwao Okamoto
    • G11B5/73G11B5/738
    • G11B5/7325G11B5/738
    • [Problem] An object is to provide a perpendicular magnetic recording medium that can realize both improvement in crystal orientation and refinement of crystal grain size and can achieve a higher recording density and a higher SN ratio, and a method of manufacturing the same.[Solution] A perpendicular magnetic recording medium 100 of the present invention is a perpendicular magnetic recording medium 100 having a base plate 100, and a laminate film including a first ground layer 150a provided on the base plate 100, a second ground layer 150b provided on the first ground layer 150a, and a main recording layer 160 provided on the second ground layer 150b and containing a magnetic material having a granular structure, wherein the magnetic material which constitutes the main recording layer 160 contains a CoCrPt alloy, and a material which constitutes the second ground layer 150b contains an Ru—Co oxide alloy.
    • [解决方案]本发明的垂直磁记录介质100是具有基板100的垂直磁记录介质100,以及包括设置在基板100上的第一接地层150a的层压膜,设置在基板100上的第二接地层150b 第一接地层150a和设置在第二接地层150b上并包含具有粒状结构的磁性材料的主记录层160,其中构成主记录层160的磁性材料包含CoCrPt合金,以及构成 第二接地层150b含有Ru-Co氧化物合金。
    • 5. 发明申请
    • APPARATUS OF MAGNETIC DISC
    • 磁盘设备
    • US20120069466A1
    • 2012-03-22
    • US13071132
    • 2011-03-24
    • Iwao OkamotoChiyo SaitoDaisuke Masuda
    • Iwao OkamotoChiyo SaitoDaisuke Masuda
    • G11B5/55
    • G11B5/012G11B5/09G11B5/1278
    • An object of the present invention is to further improve a recording density in a magnetic disk apparatus using a shingle write system.In a magnetic disk apparatus including a magnetic disk, a recording head that writes information on the magnetic disk, and a controller that controls a writing operation of the recording head to the magnetic disk, the controller controls the writing operation such that the recording head writes information on a region including a target track and a portion of track adjacent thereto in an overlapping manner while position-shifting in a radial direction of the magnetic disk and a first writing frequency to a track on which information is last written is higher than a second writing frequency to another track.
    • 本发明的目的是进一步提高使用瓦片写入系统的磁盘装置中的记录密度。 在包括磁盘的磁盘装置,在磁盘上写入信息的记录头以及控制记录头对磁盘的写入操作的控制器中,控制器控制写入操作使得记录头写入 关于包括目标轨道和与其相邻的轨道的一部分的区域的信息,当在磁盘的径向方向上的位置移位和对最后写入信息的轨道的第一写入频率高于第二 将频率写入另一个轨道。
    • 7. 发明授权
    • DNA encoding loypeptides having interferon-γ inducing activity
    • 编码具有干扰素-γ诱导活性的寡肽的DNA
    • US07037685B2
    • 2006-05-02
    • US10260576
    • 2002-10-01
    • Kozo YamamotoIwao OkamotoMasashi Kurimoto
    • Kozo YamamotoIwao OkamotoMasashi Kurimoto
    • C12P21/02
    • C07K14/54A61K38/00Y02A50/411
    • Disclosed are created stable polypeptides which are capable of inducing the production of interferon-gamma by immunocompetent cells. The present polypeptides contain specific amino acid sequences usually derived from the wild-type polypeptides, being capable of the production of interferon-gamma, by replacing the cysteine(s) with different amino acid(s). The present polypeptides possess a stability and an activity of inducing the production of IFN-γ by immunocompetent cells, both of which are significantly higher than those of the wild-type polypeptides. In addition to the activity, the present polypeptides can exhibit remarkable activities of inducing the formation of killer cells and enhancing thier cytotoxicities. The present polypeptides are easily obtainable by the process according to the present invention using recombinant DNA techniques. Thus the present polypeptides are useful for agents to treat and/or prevent susceptive diseases such as viral diseases, infections, malignant tumors, and immunopathies.
    • 公开了能够通过免疫活性细胞诱导干扰素-γ产生的稳定多肽。 本发明的多肽含有通常衍生自野生型多肽的能够产生干扰素-γ的特异性氨基酸序列,通过用不同的氨基酸替代半胱氨酸。 本发明的多肽具有通过免疫活性细胞诱导IFN-γ产生的稳定性和活性,两者均明显高于野生型多肽。 除了活性之外,本发明的多肽可以表现出显着的诱导杀伤细胞形成的活性和增强其细胞毒性。 本发明的多肽可以使用重组DNA技术通过本发明的方法容易地获得。 因此,本发明的多肽可用于治疗和/或预防感染性疾病如病毒性疾病,感染,恶性肿瘤和免疫病症的药剂。