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    • 3. 发明申请
    • Topical formulations of resorcinols and cannibinoids and methods of use
    • 间苯二酚和类别的主要配方及其使用方法
    • US20030232101A1
    • 2003-12-18
    • US10391845
    • 2003-03-18
    • Immugen Pharmaceuticals, Inc.
    • Craig R. Travis
    • A61K031/353A61K035/78
    • A61K31/35A61K9/0034A61K31/353
    • In one aspect, the invention provides a method for preventing the transmission of HIV from one individual to another. In accordance with the method, a pharmacologically-acceptable composition including at least one resorcinol derivative compound and/or cannabinoid (e.g., cannabinol derivatives, null8-THC derivatives, cannabichromene derivatives, cannabidiol derivatives, cannabigerol derivatives) (including combinations thereof) is administered topically to a first individual harboring HIV, or to a second individual at risk of infection with HIV, proximate in time with contact between the first individual and the second individual. The invention also provides topical formulations of at least one resorcinol and/or cannabinoid and water insoluble polymers as hydrogels.
    • 一方面,本发明提供了一种防止HIV从一个个体传播到另一个个体的方法。 根据该方法,局部施用包含至少一种间苯二酚衍生物化合物和/或大麻素(例如大麻酚衍生物,Delta8-THC衍生物,大麻异黄酮衍生物,大麻二酚衍生物,大麻酚衍生物)(包括其组合)的药理学上可接受的组合物 对第一个患有艾滋病毒的个体,或有第二个个人感染艾滋病毒的风险,与第一个人和第二个人之间接触的时间相近。 本发明还提供至少一种间苯二酚和/或大麻素和水不溶性聚合物作为水凝胶的局部制剂。