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1. 发明申请

US20080009701A1 FAST SPIN ECHO MRI METHOD COMPATIBLE WITH CPMG VIOLATION 有权
标题翻译：快速旋转ECHO MRI方法兼容CPMG暴露
公开(公告)号：US20080009701A1
公开(公告)日：2008-01-10
申请号：US11420224
申请日：2006-05-25
申请人： Hector E. Avram , James D. Hale , Ilya Simovsky , David M. Kramer
发明人： Hector E. Avram , James D. Hale , Ilya Simovsky , David M. Kramer
IPC分类号： A61B5/05
CPC分类号： G01R33/56341 , G01R33/5608 , G01R33/5615 , G01R33/5617 , G01R33/565 , G01R33/56509
摘要： In preferred embodiments, a fast spin echo imaging technique is provided that is insensitive to violations of the Carr Purcell Meiboom Gill (CPMG) condition. Diffusion gradients disrupt the CPMG condition, and, hence, the present fast spin echo method is compatible with diffusion measurements and diffusion weighted imaging. The preferred embodiments of the present technique involve splitting of spin echoes into echo pairs. Spin echoes are split by adjustment (in magnitude or duration) of an initial readout gradient pulse. A train of echo pairs is captured. A first image is constructed using the first echoes of each pair. Also, a second image is constructed using the second echoes of each pair. Hybrid radial Cartesian methods are used for constructing the first and second images. The first and second images are constructed independently of one another. Independent image construction renders the method insensitive to violation of the CPMG condition. Finally, the two images are combined to form a final image.
摘要翻译：在优选实施例中，提供了对违反Carr Purcell Meiboom Gill（CPMG）条件不敏感的快速自旋回波成像技术。扩散梯度破坏CPMG条件，因此，本发明的快速自旋回波方法与扩散测量和扩散加权成像兼容。本技术的优选实施例涉及将自旋回波分解为回波对。旋转回波通过初始读数梯度脉冲的调整（幅度或持续时间）分割。一串回波对被捕获。使用每对的第一个回波构建第一个图像。此外，使用每对的第二回波来构建第二图像。混合径向笛卡尔方法用于构建第一和第二图像。第一和第二图像彼此独立构建。独立的图像构造使得方法对违反CPMG条件不敏感。最后，将两张图像合并形成最终图像。

2. 发明授权

US07538548B2 Fast spin echo MRI method compatible with CPMG violation 有权
标题翻译：快速自旋回波MRI方法兼容CPMG违规
公开(公告)号：US07538548B2
公开(公告)日：2009-05-26
申请号：US11420224
申请日：2006-05-25
申请人： Hector E. Avram , James D. Hale , Ilya Simovsky , David M. Kramer
发明人： Hector E. Avram , James D. Hale , Ilya Simovsky , David M. Kramer
IPC分类号： G01V3/00
CPC分类号： G01R33/56341 , G01R33/5608 , G01R33/5615 , G01R33/5617 , G01R33/565 , G01R33/56509
摘要： In preferred embodiments, a fast spin echo imaging technique is provided that is insensitive to violations of the Carr Purcell Meiboom Gill (CPMG) condition. Diffusion gradients disrupt the CPMG condition, and, hence, the present fast spin echo method is compatible with diffusion measurements and diffusion weighted imaging. The preferred embodiments of the present technique involve splitting of spin echoes into echo pairs. Spin echoes are split by adjustment (in magnitude or duration) of an initial readout gradient pulse. A train of echo pairs is captured. A first image is constructed using the first echoes of each pair. Also, a second image is constructed using the second echoes of each pair. Hybrid radial Cartesian methods are used for constructing the first and second images. The first and second images are constructed independently of one another. Independent image construction renders the method insensitive to violation of the CPMG condition. Finally, the two images are combined to form a final image.
摘要翻译：在优选实施例中，提供了对违反Carr Purcell Meiboom Gill（CPMG）条件不敏感的快速自旋回波成像技术。扩散梯度破坏CPMG条件，因此，本发明的快速自旋回波方法与扩散测量和扩散加权成像兼容。本技术的优选实施例涉及将自旋回波分解为回波对。旋转回波通过初始读数梯度脉冲的调整（幅度或持续时间）分割。一串回波对被捕获。使用每对的第一个回波构建第一个图像。此外，使用每对的第二回波来构建第二图像。混合径向笛卡尔方法用于构建第一和第二图像。第一和第二图像彼此独立构建。独立的图像构造使得方法对违反CPMG条件不敏感。最后，将两张图像合并形成最终图像。

3. 发明申请

US20050122105A1 Water-fat separation for fast spin echo imaging in an inhomogeneous field with progressive encoding 有权
标题翻译：水分离快速自旋回波成像在不均匀的领域与渐进编码
公开(公告)号：US20050122105A1
公开(公告)日：2005-06-09
申请号：US10981739
申请日：2004-11-05
申请人： Hector Avram , Ilya Simovsky
发明人： Hector Avram , Ilya Simovsky
IPC分类号： G01R33/48 , A61B5/055 , G01R33/54 , G01V3/00
CPC分类号： G01R33/4828
摘要： A method to separate two chemically-shifted components of water (w) and fat (f) signals by: (i) estimating the field inhomogeneity β through a treatment of the residuals of the Moore-Penrose solution of the following equations: cos(αnβ)*w+cos [αn(1+β)]*f=real (In) and sin(αnβ)*w+sin [αn(1+β)]*f=imaginary (In), and (ii) using the estimated β to determine the resulting solution for w and f from the original input signals In.
摘要翻译：通过以下方式分离水（w）和脂肪（f）信号的两个化学位移分量的方法：（i）通过处理以下等式的摩尔 - 彭罗斯溶液的残差来估计场不均匀性β：cos（α （1 +β）] * f =实数（I n + N）和sin（α< （1 +β）] * f =虚数（I n + n），和（ii）使用估计的beta以从原始输入信号I N n确定w和f的结果解。

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