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    • 4. 发明申请
    • SURFACE TREATMENT METHOD AND COMPOSITION FOR ZINC COATED STEEL SHEET
    • 表面处理方法和组合镀锌钢板
    • WO1991011542A2
    • 1991-08-08
    • PCT/US1991000531
    • 1991-01-25
    • HENKEL CORPORATIONISHII, HitoshiMORI, KazuhikoMIYAWAKI, ToshiSHIMA, Shizuo
    • HENKEL CORPORATION
    • C23C22/60
    • C23C22/78C23C22/60
    • A nickel and/or cobalt deposition process which can be run at a nearly neutral pH and which rapidly deposits nickel and/or cobalt in quantities large enough to improve the paint adhesion and post coating corrosion resistance and which has a good solution stability, is achieved by treating zinc coated sheet steel with an aqueous solution that has a pH between 5 and 10 inclusive and comprises (A) a total of at least 0.01 g/L of metal ions selected from the group consisting of NI and Co ions and (B) a sufficient amount to fully complex the metal ions recited in part (A) of complexing agents selected from the group consisting of ammonia and organic compounds having at least one amino group in the neutral region. The substitution precipitation reaction of nickel and cobalt is substantially accelerated by the presence, as a third component in addition to the metal ion and complexing agent, of at least one ionic species or compound selected from the nitrite ion, nitrate ion, thiocyanate ion, thiosulfate ion, thiourea, phosphite ion, hypophosphite ion, and perchlorate ion.
    • 实现镍和/或钴沉积工艺,其可以在几乎中性的pH下运行,并且能够快速沉积足够大量的镍和/或钴,以提高涂料粘附性和后涂层耐腐蚀性并且具有良好的溶液稳定性。 通过用pH在5和10之间的水溶液处理含锌涂层钢板,包括(A)总计至少0.01g / L的选自由Ni 2+和Co 2+组成的组中的金属离子, 2+离子和(B)足够量使得部分(A)中所列的金属离子与选自氨和中性区具有至少一个氨基的有机化合物的络合剂完全复合。 作为除了金属离子和配位剂之外的至少一种离子种类或选自亚硝酸根离子,硝酸根离子,硫氰酸根离子,硫代硫酸盐的化合物的第三成分,镍和钴的取代沉淀反应基本上加快 离子,硫脲,亚磷酸根离子,次磷酸根离子和高氯酸根离子。
    • 7. 发明申请
    • ALZHEIMER'S DISEASE TREATMENT MEDICINE OR TREATMENT METHOD
    • WO2021105732A1
    • 2021-06-03
    • PCT/IB2019/001168
    • 2019-11-27
    • ISHII, Hitoshi
    • ISHII, Hitoshi
    • C12N9/64A61P25/28A61K38/00
    • The present invention relates to a medicine for treating Alzheimer's disease. [Solution] When adding acid, In Alzheimer's disease, amyloid β protein, which is a collection of fragments excised by two enzymes, β-sectorase and γ-sectorase, from amyloid β-precursor protein in brain cell membranes, accumulates to forms a mass called senile plaque. Since the two enzymes β-sectorase and γ-sectorase have optimum pH, the enzyme does not work if the pH value in the brain neurons is deviated from the optimum pH value. For the purpose of changing the hydrogen ion concentration, if acid is added to the brain neurons to make it acidic, the pH in the brain neurons changes and deviated from the optimum pH value. Because the two enzymes, β-sectorase and γ-sectorase, do not work, amyloid β-protein does not accumulate and senile plaques cannot be formed. When adding a base, In Alzheimer's disease, amyloid β protein, which is a collection of fragments excised by two enzymes β-sectorase and γ-sectorase from amyloid β-precursor protein in brain cell membranes, accumulates to forms a mass called senile plaque. Since the two enzymes β-sectorase and γ-sectorase have optimum pH the enzyme does not work if the pH value in the brain neurons is deviated from the optimum pH value. For the purpose of changing the hydrogen ion concentration if base is added to the brain neurons to make it basic, the pH in the brain neurons changes and deviated from the optimum pH value. Because the two enzymes, β-sectorase and γ-sectorase, do not work, amyloid β-protein does not accumulate and senile plaques cannot be formed.
    • 10. 发明申请
    • TREATMENT FOR THE FORMATION OF A CORROSION RESISTANT FILM ON METAL SURFACES
    • 在金属表面形成耐腐蚀膜的处理
    • WO1993009265A1
    • 1993-05-13
    • PCT/US1992008811
    • 1992-10-22
    • HENKEL CORPORATIONFURUYAMA, OsamuMORITA, RyojiISHII, Hitoshi
    • HENKEL CORPORATION
    • C23C22/28
    • B05D7/14B05D7/51B05D2301/10C09D5/08C23C22/07C23C22/08C23C22/12
    • A phosphate surface-treatment bath which contains a cationic organic polymeric compound (or salt thereof) that contains at least one cationic nitrogen atom and has a molecular weight of 1,000 to 1,000,000 forms a highly corrosion resistant film on metal surfaces (e.g., iron, zinc, aluminum, etc.) that is also an excellent paint undercoat. The film preferably is one in which the resin composed of the cationic organic compound (or salt thereof) has penetrated into the grain boundaries between phosphate crystals with an accompanying formation of a phosphate crystal/resin composite. A film formed in accordance with the present invention affords a remarkable improvement in corrosion resistance and paint adherence, compared with the phosphate conversion achieved with the same treatment, except for the omission of the organic polymer containing cationic nitrogen. In addition, even when the primer coating step is omitted, the present invention exhibits a performance approximately equivalent to the application of a primer coating on a conventional phosphate film.
    • 包含含有至少一个阳离子氮原子并具有1,000至1,000,000分子量的阳离子有机聚合物(或其盐)的磷酸盐表面处理浴在金属表面(例如铁,锌)上形成高度耐腐蚀的膜 ,铝等),其也是优异的漆底漆。 该膜优选其中由阳离子有机化合物(或其盐)组成的树脂渗透到磷酸盐晶体之间的晶界中并伴随形成磷酸盐晶体/树脂复合物。 与通过相同处理实现的磷酸盐转化率相比,根据本发明形成的膜除了含有阳离子氮的有机聚合物以外,提供了耐腐蚀性和涂料粘附性的显着改进。 此外,即使省略底漆涂布步骤,本发明也显示出与常规磷酸盐膜上底漆涂层的应用大致相同的性能。