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1. 发明申请

WO0194393A3 SYNTHETIC SPIDER SILK PROTEINS AND THE EXPRESSION THEREOF IN TRANSGENIC PLANTS 审中-公开
标题翻译：合成蜘蛛丝蛋白及其表达在转基因植物
公开(公告)号：WO0194393A3
公开(公告)日：2002-06-20
申请号：PCT/EP0106586
申请日：2001-06-11
申请人： IPK INST FUER PFLANZENGENETIK , SCHELLER JUERGEN , CONRAD UDO , GROSSE FRANK , GUEHRS KARL-HEINZ
发明人： SCHELLER JUERGEN , CONRAD UDO , GROSSE FRANK , GUEHRS KARL-HEINZ
IPC分类号： C07K14/435 , C12N15/12 , C12N15/82 , A01H5/00
CPC分类号： C12N15/8257 , C07K14/43518 , C07K14/43586
摘要： The invention relates to a DNA sequence coding for a synthetic protein, and recombinant spider silk proteins which are coded by the inventive DNA sequence. The invention also relates to methods for producing plants or plant cells containing the recombinant spider silk protein, and transgenic plants and cells containing a DNA sequence coding for a synthetic spider protein. The invention further relates to a method for obtaining a vegetable spider silk protein from transgenic plants, in addition to vegetable spider silk proteins produced according to said method.
摘要翻译：本发明涉及一种DNA序列，其为一个合成的蜘蛛丝蛋白，重组蜘蛛丝蛋白，其由本发明的DNA序列编码的方法，用于产生包含所述重组蜘蛛丝蛋白以及转基因植物细胞和植物含有DNA的植物或植物细胞中的代码包含用于合成的蜘蛛丝蛋白质序列的代码。本发明还涉及一种获得转基因植物的植物的蜘蛛丝蛋白以及植物的蜘蛛丝蛋白，其已经制备通过这样的方法的方法。

2. 发明申请

WO2004058934A3 METHOD FOR PRODUCING TRANSGENIC PLANTS HAVING AN ELEVATED VITAMIN E CONTENT BY MODIFYING THE SERINE-ACETYLTRANSFERASE CONTENT 审中-公开
标题翻译：过程产生转基因植物具有增加的维生素E含量由丝氨酸乙酰强度变化
公开(公告)号：WO2004058934A3
公开(公告)日：2004-09-02
申请号：PCT/EP0314409
申请日：2003-12-17
申请人： SUNGENE GMBH & CO KGAA , IPK INST FUER PFLANZENGENETIK , GEIGER MICHAEL , TROPF SUSANNE , SALCHERT KLAUS-DIETER , KEETMAN ULRICH , HERBERS KARIN , LEMKE RAINER , HELL RUEDIGER , WIRTZ MARKUS
发明人： GEIGER MICHAEL , TROPF SUSANNE , SALCHERT KLAUS-DIETER , KEETMAN ULRICH , HERBERS KARIN , LEMKE RAINER , HELL RUEDIGER , WIRTZ MARKUS
IPC分类号： C12N9/10 , C12N15/82
CPC分类号： C12N9/1029 , C12N15/8243
摘要： The invention relates to a method for producing transgenic plants and/or plant cells having an elevated vitamin E content, said transgenic plants and/or plant cells having a serine-acetyltransferase (SAT) content and/or activity which is modified in relation to the wild type, and/or a modified thiol compound content. The invention also relates to the use of nucleic acids coding for a SAT, for producing transgenic plants or plant cells having an elevated vitamin E content. The invention further relates to a method for producing vitamin E by cultivating transgenic plants or plant cells having a modified SAT content in relation to the wild type.
摘要翻译：本Erfndung涉及用于产生转基因植物和/或植物细胞的具有增加的维生素E含量的方法，所述转基因植物或植物细胞的相比丝氨酸乙酰转移酶（SAT）和野生型含量和/或活性改变的/ 或有硫醇化合物的改变的内容。本发明还涉及使用核酸编码的一个卫星，用于产生转基因植物或植物细胞具有增加的维生素E含量。本发明还通过培养具有相比SAT的野生型水平的改变的转基因植物或植物细胞涉及用于生产维生素E的处理。

3. 发明申请

WO0159131A3 USE OF PALATINASE AND TREHALULASE SEQUENCES AS NUTRITIVE MARKERS IN TRANSFORMED CELLS 审中-公开
标题翻译：在转化细胞使用和palatinase trehalulase序列内的营养MARKER
公开(公告)号：WO0159131A3
公开(公告)日：2002-06-20
申请号：PCT/EP0101602
申请日：2001-02-14
申请人： IPK INST FUER PFLANZENGENETIK , BOERNKE FREDERIK , SONNEWALD UWE
发明人： BOERNKE FREDERIK , SONNEWALD UWE
IPC分类号： C07K14/27 , C12N9/44 , C12N9/90 , C12N15/52 , C12N15/56 , C12N15/64 , C12N15/82 , A01H5/00 , C12N5/10
CPC分类号： C12N9/2451 , C07K14/27 , C12N9/90 , C12N15/52 , C12N15/64 , C12N15/8209
摘要： The invention relates to recombinant nucleic acid molecules containing a DNA sequence that encodes a protein with the enzymatic activity of a palatinose hydrolase, also referred to as palatinase, or a trehalulose hydrolase, also referred to as trehalulase. The invention further relates to the use of said nucleic acid molecules as selection markers in transformed cells. The invention particularly relates to recombinant nucleic acid molecules containing a DNA sequence that encodes a protein with the enzymatic activity of a palatinase or a trehalulase, said DNA sequence being under the control of regulatory sequences of a promoter that is active in plants. The invention further relates to vectors and host cells containing the recombinant nucleic acid molecules according to the invention. The invention further provides methods for producing transformed plant cells and plants using the recombinant nucleic acid molecules and vectors. The invention also relates to transgenic plants, their harvest products and propagation material as well as transgenic plant cells that contain the nucleic acid molecules or vectors according to the invention or that are produced by the methods according to the invention. The invention particularly relates to the use of DNA sequences that encode a protein with the enzymatic activity of a palatinose hydrolase or a trehalulose hydrolase as nutritive selection markers in plant cells for selecting transformed plant cells and plants. The invention also relates to a method for selecting microorganisms on a palatinose or trehalulose containing medium.
摘要翻译：本发明涉及一种含有DNA序列的重组核酸分子是指具有帕拉金糖水解酶，也称为palatinase或海藻糖水解酶的酶活性的蛋白质也被称为trehalulase，编码，以及使用这些核酸分子的如在转化细胞的选择标记。特别地，本发明涉及含有编码具有palatinase或trehalulase的酶活性的蛋白质的DNA序列的重组核酸分子，且其中所述DNA序列是下活性在植物中的启动子的调节序列的控制。本发明载体和宿主细胞包含有关新的重组核酸分子。此外，使用该重组核酸分子和载体提供了制备转化的植物细胞和植物的方法。此外，本发明涉及转基因植物，其繁殖材料和收获的产品和转基因植物细胞包含本发明核酸分子或载体，或者通过本发明的方法来制备。本发明特别涉及使用DNA Sequenze的编码蛋白质与水解酶或帕拉金糖，海藻糖水解酶在植物细胞营养选择标记转化的植物细胞和植物的选择的酶活性。本发明还涉及一种用于在帕拉金糖或含海藻糖介质的微生物的选择的方法。

4. 发明申请

WO03023018A2 A METHOD FOR ISOLATING, CULTURING AND DIFFERENTIATING INTESTINAL STEM CELLS FOR THERAPEUTIC USE 审中-公开
标题翻译：一种分离，培养和分化肠干细胞用于治疗的方法
公开(公告)号：WO03023018A2
公开(公告)日：2003-03-20
申请号：PCT/EP0210248
申请日：2002-09-12
申请人： DEVELOGEN AG , IPK INST FUER PFLANZENGENETIK , WOBUS ANNA , ROLLETSCHEK ALEXANDRA , WIESE CORNELIA , PRZEMYSLAW BLYSZCZUK , ST-ONGE LUC
发明人： WOBUS ANNA , ROLLETSCHEK ALEXANDRA , WIESE CORNELIA , PRZEMYSLAW BLYSZCZUK , ST-ONGE LUC
IPC分类号： C12N15/09 , A61K35/12 , A61K35/38 , A61L27/00 , A61P3/10 , A61P9/00 , A61P25/00 , A61P37/04 , C12N5/071 , C12N5/073 , C12N5/074 , C12N5/0793 , C12N5/10 , C12N5/00
CPC分类号： C12N5/068 , A61K35/12 , A61K35/38 , C12N5/0603 , C12N5/0619 , C12N5/067 , C12N5/0676 , C12N2506/02 , C12N2506/23 , C12N2510/02
摘要： The present invention relates to methods for the isolation, culture, and production of undifferentiated somatic intestinal stem/progenitor cells of mammalian, preferably human origins. The resulting stem/progenitor cells resemble properties of embryonic stem (ES) and multipotent progenitor cells with respect to morphology, biochemical property, and in pluripotency.
摘要翻译：本发明涉及用于分离，培养和生产哺乳动物，优选人类来源的未分化的体细胞肠干/祖细胞的方法。由此产生的干/祖细胞在形态学，生物化学性质和多能性方面类似于胚胎干细胞（ES）和多潜能祖细胞的特性。

5. 发明申请

WO02061106A2 METHOD FOR PRODUCING CYSTEINE, CYSTINE AND GLUTATHIONE BY FERMENTATION 审中-公开
标题翻译： PROCEDURE发酵生产半胱氨酸，半胱氨酸和谷胱甘肽
公开(公告)号：WO02061106A2
公开(公告)日：2002-08-08
申请号：PCT/EP0201122
申请日：2002-02-04
申请人： IPK INST FUER PFLANZENGENETIK , WIRTZ MARKUS , HELL RUEDIGER
发明人： WIRTZ MARKUS , HELL RUEDIGER
IPC分类号： C12N1/21 , C12N9/10 , C12N15/29 , C12N15/54 , C12P13/12 , C12P21/02 , C12P
CPC分类号： C12N9/1029 , C12P13/12 , C12P21/02
摘要： The invention relates to a method for detecting genes and DNA- sequences which code for the enzyme serine acetyltransferase (SAT) and are suitable for the production of cysteine by fermentation. The invention relates to a method for producing compounds containing sulphur such as cysteine, cystine and glutathione in bacteria and other host organisms by overexpression of SAT genes, wherein the host organism is disturbed in their own glutathoine synthesis.
摘要翻译：本发明涉及一种用于基因和DNA序列编码的酶丝氨酸乙酰转移（SAT）的发现的方法和适合于发酵生产半胱氨酸的。此外，本发明涉及一种用于含硫化合物如半胱氨酸，由基因的过表达SAT的装置胱氨酸和谷胱甘肽在细菌和其他宿主生物的制备方法，其中所述宿主生物体是在他自己的谷胱甘肽合成干扰。

6. 发明申请

WO0214363A3 INFLUENCING THE DISTRIBUTION OF METALS IN TRANSGENIC PLANTS 审中-公开
标题翻译： - 影响金属在转基因植物的分布
公开(公告)号：WO0214363A3
公开(公告)日：2002-07-04
申请号：PCT/EP0109518
申请日：2001-08-17
申请人： IPK INST FUER PFLANZENGENETIK , KRUEGER CLAUDIA , STEPHAN UDO W , HELL RUEDIGER
发明人： KRUEGER CLAUDIA , STEPHAN UDO W , HELL RUEDIGER
IPC分类号： C07K14/415 , C12N15/82 , C07K1/22
CPC分类号： C07K14/415 , C12N15/8259 , C12N15/8261 , C12N15/8271 , Y02A40/146 , Y02W10/37
摘要： The invention relates to a novel metal binding protein and to a method for influencing the distribution of metals in transgenic plants by expressing the metal-binding protein.
摘要翻译：本发明涉及一种新的金属结合蛋白和由金属结合蛋白的表达影响金属的转基因植物中的分布的方法。

7. 发明申请

WO0192504A3 TRIACYLGLYCEROL LIPASES FROM ARABIDOPSIS THALIANA 审中-公开
标题翻译：来自拟南芥的TRIACYLGLYCERIN-LIPASES
公开(公告)号：WO0192504A3
公开(公告)日：2002-06-20
申请号：PCT/EP0106156
申请日：2001-05-30
申请人： IPK INST FUER PFLANZENGENETIK , KOERNER MARTINA , BERNDT EKKEHART , FRITSCHE KATHRIN , FEUSSNER IVO
发明人： KOERNER MARTINA , BERNDT EKKEHART , FRITSCHE KATHRIN , FEUSSNER IVO
IPC分类号： C07K14/415 , C12N9/20 , C12N15/55 , C12N15/82 , A01H5/00 , C12Q1/68
CPC分类号： C12N15/8247 , C07K14/415 , C12N9/20
摘要： The invention relates to nucleic acid molecules, which code for proteins with the enzymatic activity of an acyl hydrolase, in particular, a triacylglycerol lipase (TAG-lipase) and method for the production of transgenic plants, which contain said nucleic acid molecules and whose acyl hydrolase content, in particular of TAG-lipase is altered in comparison to wild type plants. The invention further relates to said novel plants, the parts, products and plant cells thereof and the use of the nucleic acid molecules to influence the content of polyunsaturated fatty acids in transgenic plants.
摘要翻译：本发明涉及编码的蛋白质与酰基水解酶的酶活性，特别是三酰甘油脂肪酶（TAG脂肪酶）的核酸分子，用于生成包含这些核酸分子和它们的酰基水解酶的含量，转基因植物和特别的方法来标记脂肪酶相比被改变的野生型植物中，这些新的植物，其部分和产品，和植物细胞，以及用于影响的多不饱和脂肪酸在转基因植物中的内容的使用的核酸分子。

8. 发明申请

WO0194606A3 METHOD FOR PRODUCING C9 ALDEHYDES, C9 ALCOHOLS AND ESTERS THEREOF 审中-公开
标题翻译：用于生产C> 9 <醛，C> 9 <醇类和它们的酯
公开(公告)号：WO0194606A3
公开(公告)日：2002-05-30
申请号：PCT/EP0106584
申请日：2001-06-11
申请人： IPK INST FUER PFLANZENGENETIK , BERNDT EKKEHART , FEUSSNER IVO
发明人： BERNDT EKKEHART , FEUSSNER IVO
IPC分类号： C12N9/88 , C12P7/04 , C12P7/24 , C12P7/62 , C12N1/16 , C12N1/21 , C12N5/14 , C12N15/82
CPC分类号： C12N9/88 , C12P7/04 , C12P7/24 , C12P7/62
摘要： The invention relates to a method for producing C>9 9
摘要翻译：本发明涉及一种用于C的制备> 9 < - 醛类，C> 9 <醇及其酯，其（在多不饱和脂肪酸与重组9-脂氧合酶（9-LOX）和13-氢酶反应 13-HPL）为主。

9. 发明申请

WO2005080577A2 METHOD FOR MODULATING GIBBERELLIC ACID-DEPENDENT PROCESSES IN PLANTS 审中-公开
标题翻译：方法调制赤霉酸依赖性过程IN PLANTS
公开(公告)号：WO2005080577A2
公开(公告)日：2005-09-01
申请号：PCT/EP2005002022
申请日：2005-02-25
申请人： IPK INST FUER PFLANZENGENETIK , BAEUMLEIN HELMUT , TIEDEMANN JENS , IVANOV RUMEN , REIDT WIM , ELLERSTROEM MATS
发明人： BAEUMLEIN HELMUT , TIEDEMANN JENS , IVANOV RUMEN , REIDT WIM , ELLERSTROEM MATS
IPC分类号： C07K14/415 , C12N15/82
CPC分类号： C12N15/8297 , C07K14/415
摘要： The invention relates to a method for inhibiting gibberellic acid-dependent processes in transgenic plants by modulation of the expression of a negative regulator of gibberellic acid-controlled processes. The invention also relates to transgenic plants and plant cells with inhibited gibberellic acid-dependent processes as compared to wild-type plants or wild-type plant cells, and to the transgenic crop products and the transgenic propagation material of these transgenic plants.
摘要翻译：本发明涉及通过调制的负调节，赤霉酸控制的流程的表达抑制在转基因植物Gibberellinsäureabhängiger过程的方法。此外，本发明涉及的转基因植物和植物细胞，其在相比野生型植物或抑制Gibberellinäure依赖性过程的细胞，以及转基因收获产品和有关的转基因植物的转基因的繁殖材料。

10. 发明申请

WO2004106548A3 METHOD FOR CONDUCTING SINGLE NUCLEOTIDE POLYMORPHISMS (SNP)-ANALYSIS ON BIOCHIPS HAVING OLIGONUCLEOTIDE AREAS 审中-公开
标题翻译：方法SNP分析生物芯片上与寡核苷酸区
公开(公告)号：WO2004106548A3
公开(公告)日：2005-02-10
申请号：PCT/EP2004006002
申请日：2004-06-03
申请人： IPK INST FUER PFLANZENGENETIK , FISCHER DIRK , GEISTLINGER JOERG
发明人： FISCHER DIRK , GEISTLINGER JOERG
IPC分类号： C12Q1/68 , B01L3/00
CPC分类号： C12Q1/6837 , C12Q2535/125
摘要： The invention relates to a method for the multiparallel detection of nucleotide polymorphisms on a polydimensional array. The invention also relates to a method for detecting many individual nucleotide polymorphisms, during which the nucleotide polymorphisms of multiple individuals can be multiparallelly detected on the array. According to the invention, the hybridization of a probe molecule with a sample molecule ensues in a hybridization field on the array that is separated from surrounding hybridization fields.
摘要翻译：本发明涉及一种用于polydimensional阵列上核苷酸多态性的检测multiparallel的方法。此外，本发明涉及一种用于检测许多的单核苷酸多态性，其中多个个体的核苷酸多态性可以在阵列的多并行地检测的方法。在本发明方法的上下文中，探针分子的杂交，分别各自与在阵列，其是从周围字段杂交发生独立于杂交箱样品分子。

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