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1. 发明申请

US20140072610A1 BIOABSORBABLE TRACHEAL STENT, AND METHOD OF MANUFACTURING THEREOF 审中-公开
标题翻译：生物吸收性斜管及其制造方法
公开(公告)号：US20140072610A1
公开(公告)日：2014-03-13
申请号：US14003738
申请日：2012-03-21
申请人： Subramanian Venkatraman , Herr Cheun Anthony Ng , Yin Chiang Freddy Boey , Hsueh Yee Lynne Lim
发明人： Subramanian Venkatraman , Herr Cheun Anthony Ng , Yin Chiang Freddy Boey , Hsueh Yee Lynne Lim
IPC分类号： A61F2/04 , A61K31/407 , A61K47/32
CPC分类号： A61F2/04 , A61F2/82 , A61F2002/046 , A61K31/407 , A61K47/32 , A61L31/06 , A61L31/16 , A61L2300/00 , C08L67/04
摘要： A bioabsorbable tracheal stent is provided. The bioabsorbable stent comprises a biodegradable polymer, wherein the “ biodegradable polymer comprises about 0 to 30 wt % glycerol, polyethylene glycol, triethyl citrate, or mixture thereof. A drug is dispersed within or dissolved in the biodegradable polymer. In a second and third aspect, the invention relates to methods of manufacturing a bioabsorbable tracheal stent. The first method includes forming a solution comprising a biodegradable polymer and a drug, the biodegradable polymer comprising about 0 to 30 wt % glycerol, polyethylene glycol, triethyl citrate, or mixture thereof. The method further comprises casting the solution to form the bioabsorbable tracheal stent. The second method includes forming a polymeric stent, and dip casting the polymeric stent in a solution comprising a biodegradable polymer and a drug to form a coating on the polymeric stent, wherein the biodegradable polymer comprises about 0 to 30 wt % glycerol, polyethylene glycol, triethyl citrate, or mixture thereof.
摘要翻译：提供生物吸收性气管支架。生物可吸收性支架包括可生物降解的聚合物，其中“可生物降解的聚合物包含约0至30重量％的甘油，聚乙二醇，柠檬酸三乙酯或其混合物”，药物分散在生物可降解的聚合物中或溶于可生物降解的聚合物中，在第二和第三方面本发明涉及制造生物可吸收气管支架的方法，第一种方法包括形成包含可生物降解的聚合物和药物的溶液，所述可生物降解聚合物包含约0至30重量％的甘油，聚乙二醇，柠檬酸三乙酯或其混合物。该方法还包括浇铸该溶液以形成生物可吸收气管支架，第二种方法包括形成聚合物支架，并将聚合物支架浸入包含可生物降解聚合物和药物的溶液中以在聚合物支架上形成涂层，其中可生物降解的聚合物包含约0至30重量％的甘油，聚乙二醇，柠檬酸三乙酯或混合物t 这里。

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