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1. 发明专利

ES1066700U COLCHON PARA BEBE 未知
公开(公告)号：ES1066700U
公开(公告)日：2008-02-16
申请号：ES200702531
申请日：2007-12-05
申请人： JIA HONGYU ZHAO LI
发明人： JIA HONGYU ZHAO LI
IPC分类号： A47G27/00
摘要： 1. Colchón para bebés, estando formado por un cuerpo principal, caracterizado por el hecho de que la cabecera del cuerpo principal del colchón posee un orificio transversal para colocar la cabeza del bebé, estando dicho orificio relleno interiormente de un material esponjoso y de baja elasticidad, y recubierto por un tejido de alta transpiración.

2. 发明专利

ES1066763U ALMOHADA DE DOBLE USO 未知
公开(公告)号：ES1066763U
公开(公告)日：2008-03-01
申请号：ES200702517
申请日：2007-12-04
申请人： JIA HONGYU ZHAO LI , ZHAO LI
发明人： JIA HONGYU ZHAO LI , ZHAO LI
IPC分类号： A47G9/10
摘要： 1. Almohada de doble uso, en particular para las posiciones de decúbito lateral y decúbito supino, caracterizada por el hecho de que el cuerpo principal presenta una porción apta para la posición de decúbito supino y al menos una porción apta para la posición del decúbito lateral que tiene una altura superior al tramo para la posición de decúbito supino, estando tales porciones distribuidas horizontalmente a lo largo del cuerpo principal de la almohada.

3. 发明专利

ES1066763Y ALMOHADA DE DOBLE USO 未知
公开(公告)号：ES1066763Y
公开(公告)日：2008-08-16
申请号：ES200702517
申请日：2007-12-04
申请人： JIA HONGYU ZHAO LI
发明人： JIA HONGYU ZHAO LI , ZHAO LI
IPC分类号： A47G9/10

4. 发明专利

ES1066700Y COLCHON PARA BEBE 未知
公开(公告)号：ES1066700Y
公开(公告)日：2008-05-16
申请号：ES200702531
申请日：2007-12-05
申请人： JIA HONGYU ZHAO LI
发明人： JIA HONGYU ZHAO LI
IPC分类号： A47G27/00

5. 发明申请

US20120165532A1 One-Step Synthesis Method of 2,9-Dimethyl-4,7-Diphenyl-1,10- Phenanthroline 审中-公开
标题翻译： 2,9-二甲基-4,7-二苯基-1,10-菲咯啉的一步合成方法
公开(公告)号：US20120165532A1
公开(公告)日：2012-06-28
申请号：US13318716
申请日：2010-03-30
申请人： Lifei Cai , Weilong Zhang , Hongyu Zhao , Lei Dai
发明人： Lifei Cai , Weilong Zhang , Hongyu Zhao , Lei Dai
IPC分类号： C07D471/04
CPC分类号： C07D471/04
摘要： This invention, which belongs to the field of organic synthesis, involves “One-step synthetic method of 2,9-dimethyl-1,7-diphenyl-1,10-phenanthroline”. This method uses O-phenylenediamine and formula III to react under the condition of mixed-shrinking agent, the synthesis can be completed in one step, the stated mixed-shrinking agent is mixture of hydrochloric acid and organic acid. The organic acid serves as phase transfer catalyst and shrinking agent, meanwhile, as buffer reagent, organic acid reduces polymerization of III, and side products as well. The products gained are of high purity and the reaction is mild and easy to control. Since there is no polluting material added and generated, the waste is safe to discharge. In the after treatment of reaction, ketone solvent is used to reduce separation step and product lost, thus improving yield.
摘要翻译：属于有机合成领域的本发明涉及“2,9-二甲基-1,7-二苯基-1,10-菲咯啉的一步合成方法”。该方法使用O-苯二胺和式III在混合收缩剂的条件下反应，合成可以一步完成，所述混合收缩剂是盐酸和有机酸的混合物。有机酸用作相转移催化剂和收缩剂，同时作为缓冲剂，有机酸还可以降低III和侧产物的聚合。所得产品纯度高，反应温和，易于控制。由于没有污染物质的添加和生成，废物是安全的排放。在反应后处理中，使用酮溶剂来减少分离步骤和产物损失，从而提高产率。

6. 发明申请

US20120071695A1 Synthetic Method of 5,5-Dimethyl-2,4-Adipaldehyde-0,0-Boron Difluoride 审中-公开
标题翻译： 5,5-二甲基-2,4-己二醛-O0-硼二氟化物的合成方法
公开(公告)号：US20120071695A1
公开(公告)日：2012-03-22
申请号：US13321119
申请日：2010-05-05
申请人： Lifei Cai , Lei Dai , Hongyu Zhao , Weilong Zhang , Libai Shao , Xiaofeng Wang
发明人： Lifei Cai , Lei Dai , Hongyu Zhao , Weilong Zhang , Libai Shao , Xiaofeng Wang
IPC分类号： C07F5/02
CPC分类号： C07F5/025 , C07F5/022
摘要： This invention, which involves synthetic method of 5, 5- dimethyl-2, 4-adipaldehyde-0, 0-Boron difluoride, belongs to the field of organic synthesis. Synthetic method of 5, 5-dimethyl-2, 4-adipaldehyde-0, 0-Boron difluoride is to react pinacolone and boron trifluoride diethyl ether at low temperature, and then add aqueous alkaline solution in after treatment to extract product from ether, after that, separate fluid, condense organic phase and final product is obtained. Yield of this method is 2 to 3 times higher than that in literature, and apart from that, mild reaction condition, simple procedures, easy operation, and low cost make it easy for industrial production. The product can be used directly in next step reaction without any special purification.
摘要翻译：本发明涉及5,5-二甲基-2,4-甲二醛-O-O-二氟化硼的合成方法属于有机合成领域。 5,5-二甲基-2,4-己二醛0-0-二氟化硼的合成方法是在低温下反应频哪酮和三氟化硼二乙醚，然后在处理后加入碱性水溶液从乙醚中提取产物，之后得到分离的流体，冷凝有机相和最终产物。该方法的产量比文献中的高2〜3倍，除此之外，温和的反应条件，操作简单，操作简单，成本低，使工业生产变得容易。该产品可直接用于下一步反应，无需任何特殊的纯化。

7. 发明授权

US07169797B2 Protein-tyrosine phosphatase inhibitors and uses thereof 失效
标题翻译：蛋白质 - 酪氨酸磷酸酶抑制剂及其用途
公开(公告)号：US07169797B2
公开(公告)日：2007-01-30
申请号：US10771926
申请日：2004-02-04
申请人： Zhili Xin , Gang Liu , Zhonghua Pei , Bruce G. Szczepankiewicz , Michael D. Serby , Hongyu Zhao
发明人： Zhili Xin , Gang Liu , Zhonghua Pei , Bruce G. Szczepankiewicz , Michael D. Serby , Hongyu Zhao
IPC分类号： A61K31/445 , A61K31/41 , C07D211/32 , C07D285/12 , C07D271/06
CPC分类号： C07D413/04 , C07D261/18 , C07D413/12
摘要： The present invention is directed to compounds of formula (I), or a pharmaceutically suitable salt or prodrug thereof, which are useful for the selective inhibition of protein tyrosine phosphatase-1B (PTP1B), and are useful for the treatment of disorders caused by overexpressed or altered protein tyrosine phosphatase 1B.
摘要翻译：本发明涉及可用于选择性抑制蛋白酪氨酸磷酸酶1B（PTP1B）的式（I）化合物或其药学上合适的盐或前药，并且可用于治疗由过表达或改变的蛋白酪氨酸磷酸酶1B。

8. 发明申请

US20060173050A1 Inhibitors of c-Jun N-terminal kinases 有权
标题翻译： c-Jun N-末端激酶抑制剂
公开(公告)号：US20060173050A1
公开(公告)日：2006-08-03
申请号：US11337862
申请日：2006-01-23
申请人： Gang Liu , Hing Sham , Bruce Szczepankiewicz , Zhili Xin , Hongyu Zhao , Michael Serby , Bo Liu , Mei Liu
发明人： Gang Liu , Hing Sham , Bruce Szczepankiewicz , Zhili Xin , Hongyu Zhao , Michael Serby , Bo Liu , Mei Liu
IPC分类号： C07D213/84 , A61K31/44
CPC分类号： C07D417/12 , C07D213/73 , C07D213/81 , C07D213/84 , C07D213/85 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/04 , C07D405/12 , C07D409/04 , C07D409/12 , C07D409/14 , C07D413/04 , C07D413/06 , C07D413/10 , C07D417/06 , C07D417/10
摘要： The present invention relates to compounds that are inhibitors of c-jun N-terminal kinase 1, 2, or 3 (JNK1, JNK2, or JNK3), compositions containing the compounds and the use of the compounds in the prevention or treatment of disorders regulated by the activation of JNK1, JNK2 and JNK3.
摘要翻译：本发明涉及作为c-jun N-末端激酶1,2或3（JNK1，JNK2或JNK3）的抑制剂的化合物，含有这些化合物的组合物和该化合物在预防或治疗调节疾病中的用途通过激活JNK1，JNK2和JNK3。

9. 发明授权

US08834582B2 Apparatus for manufacturing semiconductor wafer 有权
标题翻译：半导体晶片制造装置
公开(公告)号：US08834582B2
公开(公告)日：2014-09-16
申请号：US13701880
申请日：2012-06-13
申请人： Hongyu Zhao , Xiaohong Zhang , Likun Pei , Bao Zhang , Ruiting Wang
发明人： Hongyu Zhao , Xiaohong Zhang , Likun Pei , Bao Zhang , Ruiting Wang
IPC分类号： H01L29/00 , H01L21/67 , H01L21/677
CPC分类号： H01L21/67769 , H01L21/67017 , H01L21/67742 , H01L21/67766 , Y10T29/41
摘要： The present invention provides an apparatus for manufacturing semiconductor wafer comprising at least two manipulators, at least one set of chemical gas/liquid distribution unit and an air circulating and filtering unit. The air circulating and filtering unit is separated into three regions, including the front region, the middle region, and the side region, which are controlled by respective control electric motors to achieve uniform air flow and uniform pressure in the respective regions. The cleaning degree in the internal of the apparatus can be improved by the regional control of the air circulating and filtering unit; the wafer transport efficiency can be enhanced by the double-armed manipulators having multiple degrees of freedom; and the product yield per unit area can be increased by the chemical gas/liquid distribution unit providing stable and uniform gas/liquid flow and pressure.
摘要翻译：本发明提供了一种用于制造半导体晶片的装置，其包括至少两个操纵器，至少一组化学气体/液体分配单元和空气循环和过滤单元。空气循环和过滤单元被分为包括前区域，中间区域和侧区域的三个区域，这三个区域由相应的控制电动机控制，以在各个区域中实现均匀的气流和均匀的压力。通过空气循环和过滤单元的区域控制可以改善设备内部的清洁度; 可以通过具有多个自由度的双臂操纵器来提高晶片输送效率; 可以通过化学气体/液体分配单元提高单位面积的产品产量，提供稳定和均匀的气/液流量和压力。

10. 发明申请

US20120157324A1 METHYLATION BIOMARKERS AND METHODS OF USE 审中-公开
标题翻译：甲基生物标志物及其使用方法
公开(公告)号：US20120157324A1
公开(公告)日：2012-06-21
申请号：US13390669
申请日：2010-08-17
申请人： Paul M. Lizardi , Sebastian Szpakowski , Min Chen , Jose Costa , Hongyu Zhao
发明人： Paul M. Lizardi , Sebastian Szpakowski , Min Chen , Jose Costa , Hongyu Zhao
IPC分类号： C12Q1/68 , C40B50/00 , C40B20/00 , C07H21/04 , C07H1/00
CPC分类号： C12Q1/6886 , C12Q2600/154
摘要： Disclosed are methods and compositions of assessing one or more statuses of a subject. Also disclosed are methods and compositions of identifying status biomarkers associated with a status of a subject. Also disclosed are sets of one or more status biomarkers. Also disclosed are methods and compositions of producing status biomarker capture probes.
摘要翻译：公开了评估受试者的一种或多种状态的方法和组合物。还公开了鉴定与受试者状态相关的状态生物标志物的方法和组合物。还公开了一种或多种状态生物标志物。还公开了生产状态生物标志物捕获探针的方法和组合物。

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