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1. 发明授权

US09045689B2 Yellow light afterglow material and preparation method thereof as well as LED illuminating device using same 有权
标题翻译：黄光余辉材料及其制备方法以及使用其的LED照明装置
公开(公告)号：US09045689B2
公开(公告)日：2015-06-02
申请号：US13497129
申请日：2009-11-09
申请人： Hongjie Zhang , Ming Zhang , Chengyu Li , Kun Zhao , Hao Zhang
发明人： Hongjie Zhang , Ming Zhang , Chengyu Li , Kun Zhao , Hao Zhang
IPC分类号： C09K11/80 , H01L33/00 , C09K11/77 , H01L33/50
CPC分类号： C09K11/7774 , H01L25/0753 , H01L33/502
摘要： The invention relates to a yellow light afterglow material and a preparation method thereof as well as an LED illuminating device using the same. The yellow light afterglow material comprises the chemical formula of aY2O3.bAl2O3.cSiO2:mCe.nB.xNa.yP, where a, b, c, m, n, x and y are coefficients, and a is not less than 1 but not more than 2, b is not less than 2 but not more than 3, c is not less than 0.001 but not more than 1, m is not less than 0.0001 but not more than 0.6, n is not less than 0.0001 but not more than 0.5, x is not less than 0.0001 but not more than 0.2, and y is not less than 0.0001 but not more than 0.5; wherein Y, Al and Si are substrate elements, and Ce, B, Na and P are activators. The yellow light afterglow material is prepared by the following steps: weighing oxides of elements or materials which can generate oxides at high temperature by molar ratio as raw materials, evenly mixing and then sintering the raw materials at 1200-1700° in a reducing atmosphere.
摘要翻译：本发明涉及一种黄光余辉材料及其制备方法以及使用其的LED照明装置。黄光余辉材料包括aY2O3.bAl2O3.cSiO2：mCe.nB.xNa.yP的化学式：其中a，b，c，m，n，x和y是系数，a不小于1但不是大于2，b不小于2，但不大于3，c不小于0.001，但不大于1，m不小于0.0001，但不大于0.6，n不小于0.0001，但不大于 0.5，x不小于0.0001但不大于0.2，y不小于0.0001但不大于0.5; 其中Y，Al和Si是底物，Ce，B，Na和P是活化剂。黄光余辉材料通过以下步骤制备：将以高摩尔比生成氧化物的元素或材料的氧化物称重为原料，均匀混合，然后在还原气氛中在1200-1700℃下烧结原料。

2. 发明授权

US08691825B2 Inhibitors of AKT activity 有权
标题翻译： AKT活性抑制剂
公开(公告)号：US08691825B2
公开(公告)日：2014-04-08
申请号：US13262096
申请日：2010-03-29
申请人： Qi Chen , Mingxiang Cui , Bin Hu , Shuangxi Hu , Zhifa Pu , Philip E. Sanderson , Richard Soll , Xue Tang , Jiabing Wang , Yongjin Yan , Jinfeng Yao , Hongjie Zhang
发明人： Qi Chen , Mingxiang Cui , Bin Hu , Shuangxi Hu , Zhifa Pu , Philip E. Sanderson , Richard Soll , Xue Tang , Jiabing Wang , Yongjin Yan , Jinfeng Yao , Hongjie Zhang
IPC分类号： A01N43/90 , A61K31/519 , C07D487/00
CPC分类号： A61K31/44 , C07D487/04
摘要： The instant invention provides for substituted fused pyrimidine compounds of Formula A that inhibit Akt activity: In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of treatment of cancer.
摘要翻译：本发明提供了抑制Akt活性的式A的取代的稠合嘧啶化合物：特别地，所公开的化合物选择性地抑制一种或两种Akt同种型。本发明还提供了包含这种抑制化合物的组合物和通过将该化合物给予需要治疗癌症的患者来抑制Akt活性的方法。

3. 发明申请

US20090166216A1 METHOD FOR PRODUCING A MAGNESIUM-LANTHANUM PRASEODYMIUM CERIUM INTERMEDIATE ALLOY 有权
标题翻译：生产镁 - 中华矾土中间合金的方法
公开(公告)号：US20090166216A1
公开(公告)日：2009-07-02
申请号：US12343414
申请日：2008-12-23
申请人： Jian MENG , Daqing FANG , Deping ZHANG , Jiacheng SHEN , Dingxiang TANG , Hongjie ZHANG
发明人： Jian MENG , Daqing FANG , Deping ZHANG , Jiacheng SHEN , Dingxiang TANG , Hongjie ZHANG
IPC分类号： C25C1/24
CPC分类号： C25C3/34
摘要： The invention relates to a method for producing a magnesium-rare earth intermediate alloy, which belongs to the technical field of molten salt electrolytic metallurgical technology. Inside an electrolysis oven, magnesium chloride, lanthanum praseodymium cerium chloride and potassium chloride in a controlled mass ratio of 5:(40-35):(55-60) are formulated as electrolyte composition, and the electrolysis is performed under a temperature of 800-900° C., a cathode current density of 10-30 A/cm2, and a distance between the electrodes of 4 to 8 cm; and the lanthanum praseodymium cerium chloride and the magnesium chloride are added in a mass ratio of 1:1.5-5 during the electrolysis, thus the magnesium-lanthanum praseodymium cerium intermediate alloy is produced. In the electrolysis process, neither metal magnesium nor rare earth metal is used, only the chlorides of rare earths and magnesium are used, and the rare earth ions and the magnesium ions are co-electrodeposited on the cathode, so as to obtain the intermediate alloy having a melting point close to the eutectic temperature of the rare earth and magnesium. The method has the advantages of high operability, simple process and equipment, stable quality of product by mass production, and easy for commercial scale production.
摘要翻译：本发明涉及一种属于熔盐电解冶金技术领域的镁 - 稀土中间体合金的制备方法。在电解炉内，以5：（40-35）：（55-60）的质量控制比例将氯化镁，氯化镧氯化铯和氯化钾配制成电解质组成，电解温度为800℃ -900℃，阴极电流密度为10-30A / cm 2，电极间距离为4至8cm; 并且在电解过程中以1：1.5-5的质量比加入氯化铈镧铈和氯化镁，从而制备镁 - 镧镨铈中间体合金。在电解过程中，既不使用金属镁也不使用稀土金属，仅使用稀土类和镁类的氯化物，将稀土离子和镁离子共沉积在阴极上，得到中间合金具有接近稀土和镁的共晶温度的熔点。该方法具有操作性好，工艺流程设备简单，批量生产质量稳定，易于商业化生产的优点。

4. 发明申请

US20220369572A1 A PLANT CLIMBING COLUMN 有权
公开(公告)号：US20220369572A1
公开(公告)日：2022-11-24
申请号：US17635860
申请日：2021-04-27
申请人： Hongjie Zhang
发明人： Hongjie Zhang
IPC分类号： A01G9/12
摘要： The present invention discloses a plant climbing column, comprising a climbing column body, in which a receiving hole is arranged, and at least one end of the receiving hole is open; a connecting component, arranged at the open end of the receiving hole so that the connecting component is detachably connected to the climbing column body. The connecting component can enclose the open end of the receiving hole. The present invention can improve the convenience for the use of plant climbing columns.

5. 发明授权

US09185761B2 White LED device having LED chips directly driven by alternating current 有权
标题翻译：白色LED器件，具有直接由交流电驱动的LED芯片
公开(公告)号：US09185761B2
公开(公告)日：2015-11-10
申请号：US13883832
申请日：2011-03-01
申请人： Hongjie Zhang , Ming Zhang , Chengyu Li , Kun Zhao , Dongming Li , Li Zhang
发明人： Hongjie Zhang , Ming Zhang , Chengyu Li , Kun Zhao , Dongming Li , Li Zhang
IPC分类号： H01J1/62 , H01L33/00 , H05B33/08 , H01L33/50
CPC分类号： H05B33/0845 , H01L27/15 , H01L33/502 , H05B33/0809 , H05B33/0821
摘要： An Alternate Current (AC) white Light-Emitting Diode (LED) device is provided, which belongs to the technical field of white LED manufacturing. The problem to be solved by the present invention is to low-costly overcome a series of deficiencies such as the stroboflash of an AC driven LED, and the heat dissipation difficulty caused by an integrated packaging of multiple LEDs. A white LED unit includes an LED chip and a light emitting material that can emit light when being excited by the LED chip. The luminous lifetime of the light emitting material is 1-100 ms. The LED chip only comprises one PN junction. The light emitted by the LED chip is mixed with the light emitted by the light emitting material to form white light. The white LED unit is driven by AC with a frequency not more than 100 Hz. The white LED device of prevent invention uses the single PN junction chip, rather than the prior integrated packaged AC multi-LED chip.
摘要翻译：提供交流（AC）白光发光二极管（LED）装置，属于白光LED制造技术领域。本发明要解决的问题是低成本地克服了诸如AC驱动LED的闪光灯等一系列缺陷以及由多个LED的集成封装引起的散热困难。白色LED单元包括LED芯片和当被LED芯片激发时可以发光的发光材料。发光材料的发光寿命为1-100ms。 LED芯片仅包括一个PN结。由LED芯片发出的光与由发光材料发射的光混合，形成白光。白色LED单元由AC不超过100 Hz的频率驱动。防止发明的白色LED装置使用单个PN结芯片，而不是现有的集成封装的交流多LED芯片。

6. 发明申请

US20100173288A1 SERUM/PLASMA MICRONAS AND USES THEREOF 审中-公开
公开(公告)号：US20100173288A1
公开(公告)日：2010-07-08
申请号：US12302196
申请日：2007-12-06
申请人： Chenyu Zhang , Junfeng Zhang , Xi Chen , Yi Ba , Jiangning Chen , Jin Wang , Ke Zeng , Hongjie Zhang
发明人： Chenyu Zhang , Junfeng Zhang , Xi Chen , Yi Ba , Jiangning Chen , Jin Wang , Ke Zeng , Hongjie Zhang
IPC分类号： C12Q1/68 , C12M1/34
CPC分类号： C12Q1/6886 , C12Q1/6809 , C12Q1/6876 , C12Q1/6883 , C12Q2600/158 , C12Q2600/178 , C12Q2525/207
摘要： This invention provides a combination of microRNAs for evaluating the physiological and/or pathological condition of a subject, wherein the combination comprises all detectable microRNAs stably existing in the serum/plasma of a subject; and a method for evaluating the physiological and/or pathological condition of a subject, wherein the method includes determining all detectable microRNAs stably existing in the serum/plasma of a subject; and a kit for evaluating the physiological and/or pathological condition of a subject, wherein the kit contains the tools for determining all detectable microRNAs that stably existing in the serum/plasma of a subject; and a biochip for evaluating the physiological and/or pathological condition of a subject, wherein the biochip contains the components for determining all detectable microRNAs stably existing in the serum/plasma of a subject. The aforementioned combination, method, kit and biochip can be used for diagnosis as well as differentially diagnosis of diseases including various tumors; various acute/chronic infectious diseases, e.g. viral diseases such as viral influenza, viral hepatitis, AIDS, SARS, bacterial diseases such as tuberculosis, bacterial pneumonia, and other acute/chronic infectious diseases caused by various pathogenic microorganisms; other acute/chronic diseases such as diseases of respiratory system, diseases of immune system, diseases of blood and hematopoietic system, diseases of circulatory system such as cardio-cerebrovascular diseases, metabolic diseases of endocrine system, diseases of digestive system, diseases of nervous system, diseases of urinary system, diseases of reproductive system and diseases of locomotor system, prediction of complications occurrence and malignant diseases relapse, evaluation of therapeutic effects, screening of pharmaceutical active ingredients, assessment of drug efficacy as well as forensic authentication and prohibited drug inspection and the like, possessing a number of advantages such as extensive detection spectrum, high sensitivity, low cost, convenience for sampling, ease for sample preservation, etc. The said method can be widely used in work related to general survey of diseases and so on, improve the low-specificity and low-sensitivity caused by individual differences which single markers are difficult to overcome, significantly increasing the clinical detection rate of diseases, all of which make it become an effective means for diagnosing diseases in an early phase.

7. 发明授权

US07708937B2 High-strength, high-toughness, weldable and deformable rare earth magnesium alloy 有权
标题翻译：高强度，高韧性，可焊接和可变形的稀土镁合金
公开(公告)号：US07708937B2
公开(公告)日：2010-05-04
申请号：US12105165
申请日：2008-04-17
申请人： Jian Meng , Daqing Fang , Deping Zhang , Dingxiang Tang , Huayi Lu , Lianshan Zhao , Wei Sun , Xin Qiu , Hongjie Zhang
发明人： Jian Meng , Daqing Fang , Deping Zhang , Dingxiang Tang , Huayi Lu , Lianshan Zhao , Wei Sun , Xin Qiu , Hongjie Zhang
IPC分类号： C22C23/06 , C22C23/00
CPC分类号： C22C23/04 , C22F1/06
摘要： A high-strength, high-toughness, weldable and deformable rare earth magnesium alloy comprised of 0.7˜1.7% of Ym, 5.5˜6.4% of Zn, 0.45˜0.8% of Zr, 0.02% or less of the total amount of impurity elements of Si, Fe, Cu and Ni, and the remainder of Mg, based on the total weight of the alloy. During smelting, Y, Ho, Er, Gd and Zr are added in a manner of Mg—Y-rich, Mg—Zr intermediate alloys into a magnesium melt; Zn is added in a manner of pure Zn, and at 690˜720° C., a round bar was cast by a semi-continuous casting or a water cooled mould, then an extrusion molding was performed at 380˜410° C. after cutting. Before the extrusion, the alloy is treated by the solid-solution treatment at 480˜510° C. for 2˜3 hours, however, the alloy can also be extrusion molded directly without the solid-solution treatment. After the extrusion molding, this alloy has a strength of 340 MPa or more and a percentage elongation of 14% or more at room temperature and is a high-strength, high-toughness, weldable and deformable rare earth magnesium alloy.
摘要翻译：一种高强度，高韧性，可焊接和可变形的稀土镁合金，其含有0.7〜1.7％的Ym，5.5〜6.4％的Zn，0.45〜0.8％的Zr，0.02％以下的杂质元素总量的Si，Fe，Cu和Ni，剩余的Mg基于合金的总重量。在熔炼过程中，以Mg-Y，Mg-Zr中间合金的方式将Y，Ho，Er，Gd和Zr加入到镁熔体中; 以纯Zn的方式添加Zn，在690〜720℃下，通过半连续铸造或水冷模具浇铸圆棒，然后在380〜410℃下进行挤出成型切割。在挤出前，合金在480〜510℃固溶处理2〜3小时，然而合金也可直接挤出成形而无需固溶处理。挤出成型后，该合金的室温下的强度为340MPa以上，伸长率为14％以上，为高强度，高韧性，可焊接且可变形的稀土类镁合金。

8. 发明申请

US20130221870A1 AC WHITE LED DEVICE 有权
标题翻译：交流白光LED装置
公开(公告)号：US20130221870A1
公开(公告)日：2013-08-29
申请号：US13883832
申请日：2011-03-01
申请人： Hongjie Zhang , Ming Zhang , Chengyu Li , Kun Zhao , Dongming Li , Li Zhang
发明人： Hongjie Zhang , Ming Zhang , Chengyu Li , Kun Zhao , Dongming Li , Li Zhang
IPC分类号： H05B33/08
CPC分类号： H05B33/0845 , H01L27/15 , H01L33/502 , H05B33/0809 , H05B33/0821
摘要： An Alternate Current (AC) white Light-Emitting Diode (LED) device is provided, which belongs to the technical field of white LED manufacturing. The problem to be solved by the present invention is to low-costly overcome a series of deficiencies such as the stroboflash of an AC driven LED, and the heat dissipation difficulty caused by an integrated packaging of multiple LEDs. A white LED unit includes an LED chip and a light emitting material that can emit light when being excited by the LED chip. The luminous lifetime of the light emitting material is 1-100 ms. The LED chip only comprises one PN junction. The light emitted by the LED chip is mixed with the light emitted by the light emitting material to form white light. The white LED unit is driven by AC with a frequency not more than 100 Hz. The white LED device of prevent invention uses the single PN junction chip, rather than the prior integrated packaged AC multi-LED chip.
摘要翻译：提供交流（AC）白光发光二极管（LED）装置，属于白光LED制造技术领域。本发明要解决的问题是低成本地克服了诸如AC驱动LED的闪光灯等一系列缺陷以及由多个LED的集成封装引起的散热困难。白色LED单元包括LED芯片和当被LED芯片激发时可以发光的发光材料。发光材料的发光寿命为1-100ms。 LED芯片仅包括一个PN结。由LED芯片发出的光与由发光材料发射的光混合，形成白光。白色LED单元由AC不超过100 Hz的频率驱动。防止发明的白色LED装置使用单个PN结芯片，而不是现有的集成封装的交流多LED芯片。

9. 发明申请

US20120077810A1 Inhibitors Of AKT Activity 有权
标题翻译： AKT活性抑制剂
公开(公告)号：US20120077810A1
公开(公告)日：2012-03-29
申请号：US13262096
申请日：2010-03-29
申请人： Qi Chen , Mingxiang Cui , Bin Hu , Shuangxi Hu , Zhifa Pu , Philip E. Sanderson , Richard Soll , Xue Tang , Jiabing Wang , Yongjin Yan , Jinfeng Yao , Hongjie Zhang
发明人： Qi Chen , Mingxiang Cui , Bin Hu , Shuangxi Hu , Zhifa Pu , Philip E. Sanderson , Richard Soll , Xue Tang , Jiabing Wang , Yongjin Yan , Jinfeng Yao , Hongjie Zhang
IPC分类号： A61K31/5377 , A61K31/519 , A61P35/00 , C07D487/04
CPC分类号： A61K31/44 , C07D487/04
摘要： The instant invention provides for substituted fused pyrimidine compounds that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of treatment of cancer.
摘要翻译：本发明提供抑制Akt活性的取代的稠合嘧啶化合物。特别地，所公开的化合物选择性地抑制一种或两种Akt同种型。本发明还提供了包含这种抑制化合物的组合物和通过将该化合物给予需要治疗癌症的患者来抑制Akt活性的方法。

10. 发明授权

US07744814B2 Method for producing a magnesium-lanthanum praseodymium cerium intermediate alloy 有权
标题翻译：镁镧镨铈中间合金的制造方法
公开(公告)号：US07744814B2
公开(公告)日：2010-06-29
申请号：US12343414
申请日：2008-12-23
申请人： Jian Meng , Daqing Fang , Deping Zhang , Jiacheng Shen , Dingxiang Tang , Hongjie Zhang
发明人： Jian Meng , Daqing Fang , Deping Zhang , Jiacheng Shen , Dingxiang Tang , Hongjie Zhang
IPC分类号： C25C1/24
CPC分类号： C25C3/34
摘要： Methods for producing a magnesium-rare earth intermediate alloy, which belongs to the technical field of molten salt electrolytic metallurgical technology. In one embodiment, the method comprises subjecting magnesium chloride, lanthanum praseodymium cerium chloride and potassium chloride to an electrolysis, and adding additional lanthanum praseodymium cerium chloride and magnesium chloride during the electrolysis. In the electrolysis process, neither metal magnesium nor rare earth metal is used, only the chlorides of rare earths and magnesium are used and the rare earth ions and the magnesium ions are co-electrodeposited on the cathode, so as to obtain the intermediate alloy having a melting point close to the eutectic temperature of the rare earth and magnesium. The method has various advantages including but not limited to high operability, simple process and equipment, stable quality of product by mass production and easy for commercial scale production.
摘要翻译：属于熔盐电解冶金技术领域的镁 - 稀土中间体合金的制造方法。在一个实施方案中，该方法包括使氯化镁，氯化镧镧氯化铯和氯化钾进行电解，并在电解过程中加入另外的镧氯化铈和氯化镁。在电解过程中，不使用金属镁和稀土金属，仅使用稀土和镁的氯化物，稀土离子和镁离子共沉积在阴极上，以获得具有熔点接近稀土和镁的共晶温度。该方法具有多种优点，包括但不限于可操作性高，工艺简单，设备简单，产品质量稳定，生产量大，易于商业化生产。

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