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    • 7. 发明授权
    • Foamable dentifrice composition
    • 可泡沫组合物
    • US5094840A
    • 1992-03-10
    • US600984
    • 1990-10-23
    • Kenji IsobeNobuyuki MiyajimaHiroshi Yutani
    • Kenji IsobeNobuyuki MiyajimaHiroshi Yutani
    • A61K8/00A61K8/37A61Q11/00C07C69/40
    • A61Q11/00A61K8/375C07C69/40
    • A novel foaming agent in dentifrice compositions, e.g., tooth pastes, is proposed which is an at least partially, with a basic compound, neutralized salt of a glycerin diester compound represented by the general formulaR.sup.1 --CO--O--CH.sub.2 --CHOH--CH.sub.2 --O--CO--R.sup.2,in which R.sup. 1 --CO--is a residue of a monobasic carboxylic acid having 8 to 18 carbon atoms in a molecule, e.g., lauric acid, and R.sup.2 is a residue of a polybasic carboxylic acid, e.g., succinic acid, from which one of the carboxyl groups is eliminated of which is a 1% by weight aqueous solution has a pH value in the range from 4 to 10 at 25.degree. C. The dentifrice composition compounded with 0.1-10% by weight of the above defined foaming agent has outstandingly high foamability and is advantageous in respect of the little adverse influences on the stability of enzymes contained in the dentrifrices composition.
    • 提出了一种洁齿剂组合物例如牙膏中的新型发泡剂,其至少部分为碱性化合物,由通式R 1 -CO-O-CH 2 -CHOH-CH 2所代表的甘油二酯化合物的中和盐 -O-CO-R 2,其中R 1 -CO-是分子中具有8至18个碳原子的一元羧酸的残基,例如月桂酸,R 2是多元羧酸的残基, 琥珀酸,其中一个羧基被除去,其中1重量%的水溶液在25℃下的pH值在4至10的范围内。将洁齿剂组合物与0.1-10重量% 上述定义的发泡剂具有非常高的起泡性,并且在对牙齿组合物中所含的酶的稳定性的微小的不利影响方面是有利的。