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1. 发明授权

US09273050B2 Cyclobutyl purine derivative, angiogenesis promoting agent, lumen formation promoting agent, neurocyte growth promoting agent, and drug 有权
标题翻译：环丁基嘌呤衍生物，血管生成促进剂，管腔形成促进剂，神经细胞生长促进剂和药物
公开(公告)号：US09273050B2
公开(公告)日：2016-03-01
申请号：US13130952
申请日：2009-11-27
申请人： Ikuko Tsukamoto , Ryoji Konishi , Masaaki Tokuda , Yasuo Kubota , Tokumi Maruyama , Hiroaki Kosaka , Junsuke Igarashi
发明人： Ikuko Tsukamoto , Ryoji Konishi , Masaaki Tokuda , Yasuo Kubota , Tokumi Maruyama , Hiroaki Kosaka , Junsuke Igarashi
IPC分类号： C07D473/34 , C07D473/40 , C07D473/18 , C07D473/24
CPC分类号： C07D473/18 , C07D473/24 , C07D473/34 , C07D473/40
摘要： Provided is a compound having at least one selected from the group consisting of cell growth promoting activity, angiogenesis promoting activity, lumen formation promoting activity, cell migration promoting activity, and neurocyte growth promoting activity, which is a chemically stable low-molecular-weight substance that has high absorbability and can be supplied stably at a low cost because of its low molecular weight. A cyclobutyl purine derivative, a tautomer or stereoisomer thereof, or a salt, solvate, or hydrate thereof according to the present invention is a cyclobutyl purine derivative represented by the following general formula (1), a tautomer or stereoisomer thereof, or a salt, solvate, or hydrate thereof.
摘要翻译：本发明提供一种化学稳定的低分子量物质，其具有选自细胞生长促进活性，血管生成促进活性，管腔形成促进活性，细胞迁移促进活性和神经细胞生长促进活性的至少一种化合物具有高吸收性，由于其低分子量，可以以低成本稳定地供给。根据本发明的环丁基嘌呤衍生物，其互变异构体或立体异构体或其盐，溶剂化物或水合物是由以下通式（1）表示的环丁基嘌呤衍生物，其互变异构体或立体异构体，或其盐，溶剂合物或水合物。

2. 发明授权

US08280602B2 Operation assist apparatus 有权
标题翻译：操作辅助装置
公开(公告)号：US08280602B2
公开(公告)日：2012-10-02
申请号：US12297646
申请日：2007-08-01
申请人： Masaaki Uechi , Kazuya Sasaki , Masumi Kobana , Hirokazu Nishitani , Hiroaki Kosaka
发明人： Masaaki Uechi , Kazuya Sasaki , Masumi Kobana , Hirokazu Nishitani , Hiroaki Kosaka
IPC分类号： B60K28/02
CPC分类号： B60T7/22 , B60W40/08 , B60W2050/0014
摘要： An operation assist apparatus including: an assist controller that assists a driver of a vehicle in operating the vehicle before a stop point; and a watching action detector that detects a watching action of the driver for watching the stop point. The assist controller changes an assist manner in which to assist the vehicle operation by the driver in accordance with whether the watching action is detected by the watching action detector during deceleration of the vehicle. Thus configured, the operation assist apparatus can accurately determine whether the driver will stop the vehicle at the stop point and thus can perform the vehicle operation assist appropriately.
摘要翻译：一种操作辅助装置，包括：辅助控制器，其在停止点之前辅助车辆的驾驶员操作所述车辆; 以及观察动作检测器，其检测驾驶员观看停止点的观看动作。辅助控制器根据车辆减速期间的观察动作检测器是否检测到观察动作，改变辅助驾驶员的车辆操作的辅助方式。如此构成，操作辅助装置可以准确地判断驾驶员是否会在停止点停车，能够适当地进行车辆的操作辅助。

3. 发明申请

US20110230659A1 CYCLOBUTYL PURINE DERIVATIVE, ANGIOGENESIS PROMOTING AGENT, LUMEN FORMATION PROMOTING AGENT, NEUROCYTE GROWTH PROMOTING AGENT, AND DRUG 有权
标题翻译：环磷酰胺衍生物，促血管发生剂，促红细胞生成促进剂，神经生长促进剂和药物
公开(公告)号：US20110230659A1
公开(公告)日：2011-09-22
申请号：US13130952
申请日：2009-11-27
申请人： Ikuko Tsukamoto , Ryoji Konishi , Masaaki Tokuda , Yasuo Kubota , Tokumi Maruyama , Hiroaki Kosaka , Junsuke Igarashi
发明人： Ikuko Tsukamoto , Ryoji Konishi , Masaaki Tokuda , Yasuo Kubota , Tokumi Maruyama , Hiroaki Kosaka , Junsuke Igarashi
IPC分类号： C07D473/24 , C07D473/40 , C07D473/18
CPC分类号： C07D473/18 , C07D473/24 , C07D473/34 , C07D473/40
摘要： Provided is a compound having at least one selected from the group consisting of cell growth promoting activity, angiogenesis promoting activity, lumen formation promoting activity, cell migration promoting activity, and neurocyte growth promoting activity, which is a chemically stable low-molecular-weight substance that has high absorbability and can be supplied stably at a low cost because of its low molecular weight. A cyclobutyl purine derivative, a tautomer or stereoisomer thereof, or a salt, solvate, or hydrate thereof according to the present invention is a cyclobutyl purine derivative represented by the following general formula (1), a tautomer or stereoisomer thereof, or a salt, solvate, or hydrate thereof.
摘要翻译：本发明提供一种化学稳定的低分子量物质，其具有选自细胞生长促进活性，血管生成促进活性，管腔形成促进活性，细胞迁移促进活性和神经细胞生长促进活性的至少一种化合物具有高吸收性，由于其低分子量，可以以低成本稳定地供给。根据本发明的环丁基嘌呤衍生物，其互变异构体或立体异构体或其盐，溶剂化物或水合物是由以下通式（1）表示的环丁基嘌呤衍生物，其互变异构体或立体异构体，或其盐，溶剂合物或水合物。

4. 发明申请

US20090069994A1 OPERATION ASSIST APPARATUS 有权
标题翻译：操作辅助装置
公开(公告)号：US20090069994A1
公开(公告)日：2009-03-12
申请号：US12297646
申请日：2007-08-01
申请人： Masaaki Uechi , Kazuya Sasaki , Masumi Kobana , Hirokazu Nishitani , Hiroaki Kosaka
发明人： Masaaki Uechi , Kazuya Sasaki , Masumi Kobana , Hirokazu Nishitani , Hiroaki Kosaka
IPC分类号： B60K28/02 , B60W30/08 , B60W40/08
CPC分类号： B60T7/22 , B60W40/08 , B60W2050/0014
摘要： An operation assist apparatus including: an assist controller that assists a driver of a vehicle in operating the vehicle before a stop point; and a watching action detector that detects a watching action of the driver for watching the stop point. The assist controller changes an assist manner in which to assist the vehicle operation by the driver in accordance with whether the watching action is detected by the watching action detector during deceleration of the vehicle. Thus configured, the operation assist apparatus can accurately determine whether the driver will stop the vehicle at the stop point and thus can perform the vehicle operation assist appropriately.
摘要翻译：一种操作辅助装置，包括：辅助控制器，其在停止点之前辅助车辆的驾驶员操作所述车辆; 以及观察动作检测器，其检测驾驶员观看停止点的观看动作。辅助控制器根据车辆减速期间的观察动作检测器是否检测到观察动作，改变辅助驾驶员的车辆操作的辅助方式。如此构成，操作辅助装置可以准确地判断驾驶员是否会在停止点停车，能够适当地进行车辆的操作辅助。

5. 发明授权

US5039651A Chemically activated shaped carbon, process for producing same and use thereof 失效
标题翻译：化学活化成型碳，其制造方法及其应用
公开(公告)号：US5039651A
公开(公告)日：1991-08-13
申请号：US409864
申请日：1989-09-07
申请人： Hiroaki Kosaka , Hideo Hirota , Yoshinori Iwashima
发明人： Hiroaki Kosaka , Hideo Hirota , Yoshinori Iwashima
IPC分类号： B01D53/72 , B01J20/20 , C01B31/12 , C01B31/14 , F02B1/04 , F02B75/02 , F02M25/08
CPC分类号： B01D53/72 , C01B31/12 , C01B31/125 , C01B31/14 , F02M25/089 , F02B1/04 , F02B2075/027 , Y10S95/901
摘要： A chemically activated shaped carbon suitable for adsorbing and desorbing hydrophobic organic compounds and having the specific properties in bulk density, pore volume, bulk density x pore volume, surface area, bulk density x surface area, mean pore size and the effective amount of adsorption of butane, a process for producing thereof and use thereof.
摘要翻译：适用于吸附和解吸疏水性有机化合物的化学活化成型碳，具有堆积密度，孔体积，体积密度×孔体积，表面积，体积密度×表面积，平均孔径和有效吸附量的特性丁烷，其制备方法和用途。

6. 发明授权

US5522915A Method and apparatus for sequentially and continuously determining concentrations of carbon, hydrogen, and nitrogen in molten steel, and method and apparatus for rapidly determining trace amounts of carbon in molten steel 失效
标题翻译：用于连续和连续地确定钢水中碳，氢和氮浓度的方法和装置，以及用于快速测定钢水中痕量碳的方法和装置
公开(公告)号：US5522915A
公开(公告)日：1996-06-04
申请号：US300722
申请日：1994-09-02
申请人： Akihiro Ono , Masaki Ina , Hiroaki Kosaka , Toshihiro Ogura
发明人： Akihiro Ono , Masaki Ina , Hiroaki Kosaka , Toshihiro Ogura
IPC分类号： G01N33/00 , G01N33/20 , C21C1/04
CPC分类号： G01N33/206 , G01N33/0011 , G01N33/203
摘要： Disclosed herein is a method of sequentially and continuously determining the concentrations of carbon, hydrogen, and nitrogen in molten steel using a single apparatus. Disclosed also herein are a method and an apparatus for determining trace amounts of carbon in molten steel which are the specialized application of the principle used for the above-mentioned method.Said method comprises bubbling through molten steel a carrier gas selected according to any specific element to be determined in molten steel, recovering the carrier gas containing the specific element, circulating or passing the recovered carrier gas through a gas circulating circuit so that the concentration of the specific element in the carrier gas reaches an approximate or complete equilibrium with the concentration of the specific element in molten steel, determining the concentration of the specific element by the means to determine the concentration of one or more specific elements, (and in the case of determination of several elements) discharging the carrier gas from the gas circulating circuit and repeating said steps with a renewed carrier gas to determine the remaining elements to be determined.
摘要翻译：本文公开了使用单个装置依次和连续地测定钢水中的碳，氢和氮的浓度的方法。本文还公开了用于测定钢水中痕量碳的方法和装置，这是用于上述方法的原理的专门应用。所述方法包括通过钢水鼓泡根据钢水中要确定的任何特定元素选择的载气，回收含有特定元素的载气，使回收的载气循环或通过气体循环回路，使浓度载气中的特定元素与钢水中特定元素的浓度达到近似或完全平衡，通过确定一种或多种特定元素浓度的方法确定特定元素的浓度（以及在确定几个元件）从气体循环回路排出载气并用更新的载气重复所述步骤以确定待确定的剩余元素。

7. 发明申请

US20060201806A1 Method of forming thin film layer on external surface of sensor and sensor manufactured therewith 审中-公开
标题翻译：在传感器和传感器的外表面上形成薄膜层的方法
公开(公告)号：US20060201806A1
公开(公告)日：2006-09-14
申请号：US10544846
申请日：2004-02-27
申请人： Masanori Iwase , Kiyoshi Matsushita , Hideki Watanabe , Yukio Terauchi , Hiroaki Kosaka
发明人： Masanori Iwase , Kiyoshi Matsushita , Hideki Watanabe , Yukio Terauchi , Hiroaki Kosaka
IPC分类号： G01N27/26 , B05D5/12 , B05D5/00
CPC分类号： G01N27/4115
摘要： It is an object of the present invention to provide a method for forming a thin-film layer on the outer surface of a sensor, by which a thin-film layer formed on the surface of a sensor used for measuring the concentration of elements contained in the measurement object such as a molten metal, slag, or gas, can be easily provided with a complex pattern shape of small thickness and a uniformly arranged pattern shape. The method is provided for forming a thin-film layer of a sensor composed of a solid electrolyte which is a molded body having an inner space, a reference substance filled in the inner space, a reference electrode connected to the reference substance and led out to the outside of the inner space, and a thin-film layer comprising a ceramic powder or a metal powder as the main component and formed on the outer surface of the solid electrolyte in such a manner that part of the outer surface is exposed. This thin-film layer is formed by printing.
摘要翻译：本发明的目的是提供一种在传感器的外表面上形成薄膜层的方法，通过该方法形成在用于测量包含的元素的浓度的传感器的表面上的薄膜层诸如熔融金属，渣或气体的测量对象可以容易地具有小厚度和均匀排列的图案形状的复杂图案形状。该方法用于形成由固体电解质构成的传感器的薄膜层，所述固体电解质是具有内部空间的成型体，填充在内部空间中的参考物质，与参考物质连接的参考电极，内部空间的外部，以及包含陶瓷粉末或金属粉末作为主要成分的薄膜层，并且以暴露外表面的一部分的方式形成在固体电解质的外表面上。该薄膜层通过印刷形成。

8. 发明授权

US5118329A Process for recovering a hydrophobic organic compound by absorption and desorption with a chemically activated shaped carbon 失效
标题翻译：通过用化学活化的成型碳吸收和解吸来回收疏水性有机化合物的方法
公开(公告)号：US5118329A
公开(公告)日：1992-06-02
申请号：US699953
申请日：1991-05-14
申请人： Hiroaki Kosaka , Hideo Hirota , Yoshinori Iwashima
发明人： Hiroaki Kosaka , Hideo Hirota , Yoshinori Iwashima
IPC分类号： B01D53/72 , B01J20/20 , C01B31/12 , C01B31/14 , F02B1/04 , F02B75/02 , F02M25/08
CPC分类号： B01D53/72 , C01B31/12 , C01B31/125 , C01B31/14 , F02M25/089 , F02B1/04 , F02B2075/027 , Y10S95/901
摘要： Process of recovering a hydrophobic organic compound(s) by contacting a chemically activated shaped carbon with a hydrophobic organic compound to repeatedly absorb and desorb the compound, thereby recovering the same. The activated carbon is such that it has a bulk density of 0.25 to 0.6 g/cm.sup.3, a pore volume of 0.65 to 1.2 cm.sup.3 /g, a bulk density.times.pore volume of 0.25 to 0.4 cm.sup.3 /cm.sup.3, a surface area of at least 1000 m.sup.2 /g, a mean pore size of 18 to 35 angstroms, a bulk density.times.surface area of at least 400 m.sup.2 /cm.sup.3, and which chemically activated carbon effectively adsorbs butane in an amount of 8.0 to 15 g/100 ml. The process is especially suitable for absorbing gasoline vapor in an automobile exhaust and releasing the absorbed gasoline for reuse in the operation of the engine.
摘要翻译：通过使化学活化的成形碳与疏水性有机化合物接触来反复吸收和解吸该化合物，从而回收疏水性有机化合物，从而回收疏水性有机化合物。活性炭的体积密度为0.25〜0.6g / cm 3，孔体积为0.65〜1.2cm 3 / g，体积密度孔体积为0.25〜0.4cm 3 / cm 3，表面积为1000m 2 平均孔径为18〜35埃，体积密度面积为400平方米/立方厘米以上，化学活性炭有效吸附量为8.0〜15克/毫升的丁烷。该方法特别适用于吸收汽车尾气中的汽油蒸气并释放吸收的汽油以便在发动机的运行中再次使用。

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