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    • 5. 发明授权
    • Multiple-source imaging system with flat-panel detector
    • 具有平板检测器的多源成像系统
    • US08891726B2
    • 2014-11-18
    • US12864880
    • 2009-02-02
    • Herfried WieczorekGereon Vogtmeier
    • Herfried WieczorekGereon Vogtmeier
    • G06K9/00A61B6/00A61B6/03
    • A61B6/4007A61B6/032A61B6/4014A61B6/4028A61B6/4233A61B6/4447A61B6/4488
    • When performing nuclear (e.g., SPECT or PET) and CT scans on a patient, an imaging system (10) includes three or more carbon nanotube x-ray sources (20) are circumferentially spaced along an arc of a rotatable gantry (16) that spans a distance larger than a maximum cross-sectional dimension of a section of a patient (14) to be imaged. The x-ray sources are sequentially pulsed to emit x-rays for scanning a section of a patient (14) including a volume of interest (VOI) (13). Only one source (20) is in an ON state at a time to create a duty cycle, which reduces cooling time for the respective sources as well as radiation dose to the subject. X-rays traversing the patient (14) are received at a flat panel x-ray detector (22) that has a width smaller than the maximum cross-sectional dimension, which further reduces the weight and size of the system (10).
    • 当对患者进行核(例如SPECT或PET)和CT扫描时,成像系统(10)包括三个或更多个碳纳米管x射线源(20)沿着可旋转机架(16)的圆弧沿圆周间隔开, 跨越要被成像的患者(14)的一部分的最大横截面尺寸的距离。 x射线源被顺序地脉冲以发射X射线,用于扫描包括感兴趣体积(VOI)(13)的患者(14)的一部分。 一次只有一个源(20)处于ON状态以创建占空比,这降低了各个源的冷却时间以及对被摄体的辐射剂量。 穿过患者(14)的X射线被接收在具有小于最大横截面尺寸的宽度的平板X射线检测器(22)上,这进一步减小了系统(10)的重量和尺寸。
    • 6. 发明授权
    • Dynamic PET imaging with isotope contamination compensation
    • 动态PET成像与同位素污染补偿
    • US08692681B2
    • 2014-04-08
    • US13382191
    • 2010-06-15
    • Herfried WieczorekFrank O. ThieleManoj V. Narayanan
    • Herfried WieczorekFrank O. ThieleManoj V. Narayanan
    • G08B21/00
    • G01T1/2985A61B6/037
    • A nuclear imaging system includes a scanner (8), such as a PET scanner. A patient is injected with a [13N]ammonia radioisotope tracer which is contaminated with a small percent of 18F contamination. The scanner receives radiation from the injected tracer and a reconstruction processor (28) reconstructs the detected radiation into image representations. A calibration processor (16) generates an estimated decay curve based on the proton bombardment and a priori information about the tracer. An activity meter (42) measures radiation emitted from a sample of the tracer and a dose calibrator (44) determines a decay curve from the measured radiation. The detected radiation is corrected with one of the decay curves during reconstruction or a correction processor (50) corrects reconstructed images with one or both of the decay curves. A display (14) displays uncorrected reconstructed images and the decay curve and/or the corrected images.
    • 核成像系统包括诸如PET扫描仪的扫描器(8)。 注射一个[13N]氨放射性同位素示踪剂,其被少量的18F污染物污染。 扫描仪接收来自被注入示踪剂的辐射,并且重建处理器(28)将检测到的辐射重建成图像表示。 校准处理器(16)基于质子轰击和关于示踪器的先验信息产生估计衰减曲线。 活性计量器(42)测量从示踪剂的样品发射的辐射,剂量校准器(44)从测量的辐射确定衰减曲线。 在重建过程中用一个衰减曲线来校正检测到的辐射,或者校正处理器(50)用一个或两个衰减曲线校正重建图像。 显示器(14)显示未校正的重建图像和衰减曲线和/或校正图像。
    • 7. 发明申请
    • DYNAMIC PET IMAGING WITH ISOTOPE CONTAMINATION COMPENSATION
    • 动态PET成像与同位素污染补偿
    • US20120098671A1
    • 2012-04-26
    • US13382191
    • 2010-06-15
    • Herfried WieczorekFrank O. ThieleManoj V. Narayanan
    • Herfried WieczorekFrank O. ThieleManoj V. Narayanan
    • G08B21/00A61B6/00
    • G01T1/2985A61B6/037
    • A nuclear imaging system includes a scanner (8), such as a PET scanner. A patient is injected with a [13N]ammonia radioisotope tracer which is contaminated with a small percent of 18F contamination. The scanner receives radiation from the injected tracer and a reconstruction processor (28) reconstructs the detected radiation into image representations. A warning generator (12) generates warnings to the clinician concerning the effects of the 18F contamination. A calibration processor (16) generates an estimated decay curve based on a time since the end of the proton bombardment which created the tracer and a priori information about the tracer. An activity meter (42) measures radiation emitted from a sample of the tracer and a dose calibrator (44) determines a decay curve from the measured radiation. Either the detected radiation is corrected in accordance with one of the decay curves during reconstruction or a correction processor (50) corrects reconstructed images in accordance with one or both of the decay curves. A display (14) displays uncorrected reconstructed images and the decay curve and/or the corrected images.
    • 核成像系统包括诸如PET扫描仪的扫描器(8)。 注射一个[13N]氨放射性同位素示踪剂,其被少量的18F污染物污染。 扫描仪接收来自被注入示踪剂的辐射,并且重建处理器(28)将检测到的辐射重建成图像表示。 警告发生器(12)向临床医生发出关于18F污染的影响的警告。 校准处理器(16)基于自产生示踪剂的质子轰击结束以及关于示踪剂的先验信息之后的时间产生估计衰减曲线。 活性计量器(42)测量从示踪剂的样品发射的辐射,剂量校准器(44)从测量的辐射确定衰减曲线。 根据重建期间的衰减曲线之一校正检测到的辐射,或者校正处理器(50)根据衰减曲线中的一个或两个来校正重建图像。 显示器(14)显示未校正的重建图像和衰减曲线和/或校正图像。
    • 9. 发明申请
    • X-ray examination apparatus
    • X光检查仪
    • US20060056593A1
    • 2006-03-16
    • US10535058
    • 2003-10-27
    • Herfried Wieczorek
    • Herfried Wieczorek
    • H05G1/58H05G1/54
    • H01L27/14676
    • An x-ray examination apparatus comprises an x-ray source and an x-ray detector. The x-ray detector includes a photoconductor to derive electric charges from incident x-radiation and read-out elements which derive electrical pixel-signals from the electric charges from the photoconductor. A central group of the read-out elements is located in a central region of the x-ray detector and a peripheral group of the read-out elements is located in a peripheral region which surrounds the central region. The x-ray examination apparatus being provided with a selection system to select the central group of read-out elements so as to supply pixel-signals from the central group of read-elements to the output circuit. The selection system may include an encompassing electrode to drain electric charges from the peripheral group. Or the selection system shields the peripheral group from x-rays.
    • x射线检查装置包括x射线源和x射线检测器。 X射线检测器包括光电导体,以从入射的X射线和读出元件导出电荷,该元件从光电导体得到电子像素信号。 读出元件的中心组位于x射线检测器的中心区域,并且读出元件的外围组位于围绕中心区域的外围区域中。 X射线检查装置设置有选择系统,以选择读出元件的中心组,以便将来自读取元件的中心组的像素信号提供给输出电路。 选择系统可以包括围绕电极排出来自周边组的电荷。 或者选择系统屏蔽外围组与X射线。