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1. 发明授权

US5700087A Device maximizing dispersion of aggregate in liquid diluent 失效
标题翻译：设备最大化聚集体在液体稀释剂中的分散
公开(公告)号：US5700087A
公开(公告)日：1997-12-23
申请号：US540022
申请日：1995-10-06
申请人： Arnold H. Beckett , James E. Swon , Henry Z. Hofer
发明人： Arnold H. Beckett , James E. Swon , Henry Z. Hofer
IPC分类号： B01F15/00 , B01F7/16
CPC分类号： B01F15/00824
摘要： For specialized use to secure reliable standardized complete distribution or solution of aggregate mixed into a liquid diluent, a vessel having an interior hemispherical concave bottom having extending upwardly centrally from the concave bottom an arcuate conical member having upright concavely-shaped circumscribing sides. The vessel is taken in conjunction with a stably mounted mixing structure having a downwardly-extending shaft and mixing blades thereof. The shaft on a lower portion thereof supports balanced mixing blades extending radially outwardly from the mixing shaft. The mixing blades are positioned to be substantially spaced below a predetermined liquid level of liquid diluent containing a dissolvable or suspendable aggregate and to be substantially spaced above an upper end of the centrally upwardly arcuate conical member. The blades when positioned and when the mixing structure is set to revolvably the blade at a predetermined result-intensive rpm, results in homogeneously distributed aggregate in liquid contained diluent.
摘要翻译：为了专门用于确保混合到液体稀释剂中的可靠的标准化完全分布或聚集体的溶液，具有从凹形底部向中心向上延伸的内部半球状凹形底部的容器具有直立的凹形形状的外接侧面的弓形锥形构件。容器与具有向下延伸的轴和混合叶片的稳定安装的混合结构结合。其下部的轴支撑从混合轴径向向外延伸的平衡混合叶片。混合叶片被定位成基本上间隔在包含可溶解或可悬浮聚集体的液体稀释剂的预定液面以下并且基本上间隔在中心向上的弓形锥形构件的上端上方。当定位的叶片和当混合结构以预定的结果密集转速设定为可转动的叶片时，导致在液体含有稀释剂中的均匀分布的聚集体。

2. 发明授权

US07332128B2 Fiber-optic dissolution systems devices, and methods 失效
标题翻译：光纤溶解系统装置及方法
公开(公告)号：US07332128B2
公开(公告)日：2008-02-19
申请号：US10838907
申请日：2004-05-03
申请人： C. J. Anthony Fernando , James E. Swon , Henry Z. Hofer
发明人： C. J. Anthony Fernando , James E. Swon , Henry Z. Hofer
IPC分类号： G01N21/00
CPC分类号： G01N21/8507 , G01N13/00 , G01N21/253 , G01N33/15 , G01N2013/006 , G01N2021/8521 , G01N2021/8528 , Y10T436/117497 , Y10T436/2575
摘要： A dissolution system provides remote flow cells integrated into a manifold device. The manifold device communicates with liquid input and output lines associated with each flow cell, as well as fiber-optic input and output lines associated with each flow cell. Liquid samples are respectively drawn from dissolution vessels, optically-related measurements are taken, and the samples are thereafter returned their respective vessels. The manifold device can be adapted to receive probe-type instruments that incorporate the fiber-optics, wherein each probe-type instrument is associated with each flow cell. Alternatively, each corresponding pair of fiber-optic input and output lines are disposed in opposing, optically-aligned relation and probe-type instruments are not used. The gap between the ends of the opposing fiber-optic lines provides a light path across the corresponding flow cell. Calibration procedures using blank and/or standard media are performed using the same flow cells, with provisions made for bypassing the vessels in which the samples to be analyzed are held.
摘要翻译：溶解系统提供集成在歧管装置中的远程流动池。歧管装置与与每个流动池相关联的液体输入和输出线路以及与每个流动池相关联的光纤输入和输出线路通信。液体样品分别从溶解容器中抽出，进行光学相关测量，然后将样品返回其各自的容器。歧管装置可以适于接纳包含光纤的探针型仪器，其中每个探针型仪器与每个流动池相关联。或者，每个对应的一对光纤输入和输出线以相对的光学对准关系设置，并且不使用探针型仪器。相对的光纤线路的端部之间的间隙提供穿过相应的流动池的光路。使用空白和/或标准介质的校准程序使用相同的流动池进行，其中为绕过待分析样品的容器进行旁路。

3. 发明授权

US06764651B2 Fiber-optic dissolution systems, devices, and methods 失效
标题翻译：光纤溶解系统，装置和方法
公开(公告)号：US06764651B2
公开(公告)日：2004-07-20
申请号：US10014270
申请日：2001-11-07
申请人： C. J. Anthony Fernando , James E. Swon , Henry Z. Hofer
发明人： C. J. Anthony Fernando , James E. Swon , Henry Z. Hofer
IPC分类号： G01N2101
CPC分类号： G01N21/8507 , G01N13/00 , G01N21/253 , G01N33/15 , G01N2013/006 , G01N2021/8521 , G01N2021/8528 , Y10T436/117497 , Y10T436/2575
摘要： A dissolution system provides remote flow cells integrated into a manifold device. The manifold device communicates with liquid input and output lines associated with each flow cell, as well as fiber-optic input and output lines associated with each flow cell. Liquid samples are respectively drawn from dissolution vessels, optically-related measurements are taken, and the samples are thereafter returned their respective vessels. The manifold device can be adapted to receive probe-type instruments that incorporate the fiber-optics, wherein each probe-type instrument is associated with each flow cell. Alternatively, each corresponding pair of fiber-optic input and output lines are disposed in opposing, optically-aligned relation and probe-type instruments are not used. The gap between the ends of the opposing fiber-optic lines provides a light path across the corresponding flow cell. Calibration procedures using blank and/or standard media are performed using the same flow cells, with provisions made for bypassing the vessels in which the samples to be analyzed are held.
摘要翻译：溶解系统提供集成在歧管装置中的远程流动池。歧管装置与与每个流动池相关联的液体输入和输出线路以及与每个流动池相关联的光纤输入和输出线路通信。液体样品分别从溶解容器中抽出，进行光学相关测量，然后将样品返回其各自的容器。歧管装置可以适于接纳包含光纤的探针型仪器，其中每个探针型仪器与每个流动池相关联。或者，每个对应的一对光纤输入和输出线以相对的光学对准关系设置，并且不使用探针型仪器。相对的光纤线路的端部之间的间隙提供穿过相应的流动池的光路。使用空白和/或标准介质的校准程序使用相同的流动池进行，其中为绕过待分析样品的容器进行旁路。

4. 发明授权

US5540496A Solute dissolution reciprocating flow-cell 失效
标题翻译：溶质溶解往复流动池
公开(公告)号：US5540496A
公开(公告)日：1996-07-30
申请号：US528788
申请日：1995-09-18
申请人： Arnold H. Beckett , James F. Swon , Henry Z. Hofer
发明人： Arnold H. Beckett , James F. Swon , Henry Z. Hofer
IPC分类号： B01F9/00 , B01F11/00 , B01F13/00 , B01F15/06
CPC分类号： B01F11/0077 , B01F13/005 , B01F9/00
摘要： A combination of a flow-cell with a rate of flow controllable and set to obtain and maintain a solvent or diluent predetermined low flow pressure from the flow-cell's inlet to the flow-cell's outlet, in which at-least an outlet thereof is alternately raised to a height above the inlet thereof sufficiently relative to mass of individual solute(s) and/or individual bead(s) (or other insoluble mass(es)) as to permit the mass of the individual solute(s) and/or individual bead(s) to move by gravity from a direction of the outlet end toward the inlet end of the flow-cell as part of a mechanism ascertainable of improved dissolving of solute and/or suspension of particles of insoluble matter.
摘要翻译：流动池与流速可组合以设定以获得并保持溶剂或稀释剂预定的低流量压力，从流动池的入口到流通池的出口，其中至少一个出口是交替的相对于单个溶质和/或单个珠粒（或其它不溶质量）的质量足够地升高到入口上方的高度，以允许单个溶质的质量和/或通过重力从出口端的方向朝向流动池的入口端移动的单个珠子作为确定可改善溶解和/或不溶物质颗粒的悬浮液的机制的一部分。

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