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1. 发明申请

US20110273715A1 DIAGNOSTIC TAPE UNIT AND DIAGNOSTIC MEASURING SYSTEM 有权
标题翻译：诊断胶带单元和诊断测量系统
公开(公告)号：US20110273715A1
公开(公告)日：2011-11-10
申请号：US12940368
申请日：2010-11-05
申请人： Peter Seelig , Helmut Leininger
发明人： Peter Seelig , Helmut Leininger
IPC分类号： G01N21/55
CPC分类号： G01N21/55 , A61B5/14532 , A61B5/1455 , A61B2562/0295 , B01L3/505 , B01L9/523 , B01L2300/0654 , B01L2300/0812 , B01L2300/0825 , B01L2300/0841 , G01N21/8483 , G01N33/48764 , G01N33/66
摘要： The invention concerns a diagnostic tape unit with a test tape that can be wound onto a spool which comprises a transport tape and a plurality of test elements mounted thereon, where the test elements have an analytical reagent layer, a carrier foil supporting the reagent layer and a piece of adhesive tape connecting the carrier foil with the transport tape, and where the front side of the reagent layer facing away from the carrier foil is designed for the application of a sample substance. According to the invention it is proposed that the test elements in combination with the light transmitting transport tape in each case form an optical multi-layer system for a rear-side reflection-photometric measurement of the reagent layer.
摘要翻译：本发明涉及一种诊断带单元，其具有可以缠绕在卷轴上的测试带，该卷轴包括传送带和安装在其上的多个测试元件，其中测试元件具有分析试剂层，载体箔支撑试剂层，将载体箔与输送带连接的一段粘合带，并且试剂层的背离载体箔的前侧被设计用于施加样品物质。根据本发明，提出了与各透光性输送带组合的测试元件形成用于对试剂层进行背面反射测光的光学多层系统。

2. 发明授权

US07479253B2 Method of assembling a diagnostic test strip having a functional overlay 失效
标题翻译：组装具有功能覆盖层的诊断测试条的方法
公开(公告)号：US07479253B2
公开(公告)日：2009-01-20
申请号：US10360966
申请日：2003-02-07
申请人： Wolfgang-Reinhold Knappe , Helmut Leininger , Ralf Steinbrueck , Franz Wittmann
发明人： Wolfgang-Reinhold Knappe , Helmut Leininger , Ralf Steinbrueck , Franz Wittmann
IPC分类号： G01N30/00
CPC分类号： G01N33/525
摘要： A flat-shaped functional overlay for at least one region of a flat-shaped flexible object which does not form a fold when the sandwich composed of the flexible object and overlay is bent towards the side on which the overlay is located is described. The overlay is composed of one or several flat-shaped overlays which are attached to the flexible object in such a way that a part of their surface can move freely relative to the surface of the object covered by this part in the direction of curvature produced when the object is bent.In addition diagnostic test strips are described which have such an overlay.
摘要翻译：描述了当由柔性物体和覆盖层构成的夹层由朝向覆盖层所在的一侧弯曲时，平面状柔性物体的至少一个区域的平坦形功能覆盖层不会形成折痕。覆盖层由一个或多个平面形状的叠层组成，这些叠层以这样的方式附接到柔性物体上，使得其表面的一部分相对于被该部分覆盖的物体的表面在所产生的曲率方向上自由移动，物体弯曲。此外，描述了具有这样的覆盖层的诊断测试条。

3. 发明授权

US5846837A Volume-independent diagnostic test carrier and methods in which it is used to determine an analyte 失效
标题翻译：体积独立的诊断测试载体及其用于确定分析物的方法
公开(公告)号：US5846837A
公开(公告)日：1998-12-08
申请号：US900401
申请日：1997-07-21
申请人： Detlef Thym , Helmut Leininger
发明人： Detlef Thym , Helmut Leininger
IPC分类号： G01N31/22 , G01N33/52 , G01N33/66 , G01N33/49
CPC分类号： G01N33/521 , Y10T436/25375
摘要： The present invention concerns a diagnostic test carrier (1) containing a supporting layer (2) with a detection layer (3) arranged thereon containing the reagents required to determine analyte in a liquid sample and a network (4) covering the detection layer (3) which is larger than the detection layer (3) and which is attached to the supporting layer (2), which is characterized in that the network (4) is hydrophilic but not capillary active on its own and an inert cover (5) made of sample-impermeable material is arranged over the areas (6) of the network that extend beyond the detection layer in such a way that a sample application site (7) remains free on the region of the network (4) covering the detection layer as well as the use of such a test carrier for the determination of analyte in a liquid. In addition the invention concerns a method for the determination of an analyte in a liquid sample with the aid of a test carrier according to the invention.
摘要翻译：本发明涉及一种包含支撑层（2）的诊断测试载体（1），其上布置有检测层（3），其上包含测定液体样品中的分析物所需的试剂和覆盖检测层（3）的网络（4）），其大于所述检测层（3）并且附接到所述支撑层（2），其特征在于，所述网络（4）本身是亲水的但不是毛细管活动的，并且惰性盖（5）制成样品不可渗透材料布置在网络的延伸超过检测层的区域（6）上，使得样品施加部位（7）在覆盖检测层的网络（4）的区域上保持空闲，如以及使用这种测试载体来测定液体中的分析物。此外，本发明涉及借助于根据本发明的测试载体来确定液体样品中的分析物的方法。

4. 发明授权

US07975842B2 Outer packaging system for medical consumables 有权
标题翻译：医疗耗材外包装系统
公开(公告)号：US07975842B2
公开(公告)日：2011-07-12
申请号：US11612889
申请日：2006-12-19
申请人： Bruno Thoes , Udo Manser , Helmut Leininger
发明人： Bruno Thoes , Udo Manser , Helmut Leininger
IPC分类号： B65D81/26 , G01N21/00
CPC分类号： G01N33/48764 , G01N33/48778
摘要： The invention relates to a packaging system for medical consumables, in particular test elements. The packaging system comprises an outer packaging, which accommodates a first desiccant supply, and a magazine with an unused test element supply. In the closed state of the outer packaging, the first desiccant supply of the outer packaging acts on the interior of the magazine via a connection that permits water vapor diffusion. In exemplary embodiments, the magazine includes a second desiccant supply. The communication of water vapor between the magazine and outer package reduces the load on the desiccant supply in the magazine.
摘要翻译：本发明涉及用于医疗消耗品，特别是测试元件的包装系统。包装系统包括容纳第一干燥剂供应的外包装和具有未使用的测试元件供应的盒。在外包装的关闭状态下，外部包装的第一干燥剂供应通过允许水蒸气扩散的连接件作用在盒的内部。在示例性实施例中，盒包括第二干燥剂供应。杂志和外包装之间的水蒸气通讯减少了杂志中干燥剂供应的负担。

5. 发明申请

US20070151884A1 OUTER PACKAGING SYSTEM FOR MEDICAL CONSUMABLES 有权
标题翻译：医疗消费外包装系统
公开(公告)号：US20070151884A1
公开(公告)日：2007-07-05
申请号：US11612889
申请日：2006-12-19
申请人： Bruno Thoes , Udo Manser , Helmut Leininger
发明人： Bruno Thoes , Udo Manser , Helmut Leininger
IPC分类号： A61B19/02 , B65D81/26
CPC分类号： G01N33/48764 , G01N33/48778
摘要： The invention relates to a packaging system for medical consumables, in particular test elements. The packaging system comprises an outer packaging, which accommodates a first desiccant supply, and a magazine with an unused test element supply. In the closed state of the outer packaging, the first desiccant supply of the outer packaging acts on the interior of the magazine via a connection that permits water vapor diffusion. In exemplary embodiments, the magazine includes a second desiccant supply. The communication of water vapor between the magazine and outer package reduces the load on the desiccant supply in the magazine.
摘要翻译：本发明涉及用于医疗消耗品，特别是测试元件的包装系统。包装系统包括容纳第一干燥剂供应的外包装和具有未使用的测试元件供应的盒。在外包装的关闭状态下，外部包装的第一干燥剂供应通过允许水蒸气扩散的连接件作用在盒的内部。在示例性实施例中，盒包括第二干燥剂供应。杂志和外包装之间的水蒸气通讯减少了杂志中干燥剂供应的负担。

6. 发明授权

US06231815B1 Storage and transport system for sample material 失效
标题翻译：储存和运输系统样品
公开(公告)号：US06231815B1
公开(公告)日：2001-05-15
申请号：US08974481
申请日：1997-11-20
申请人： Gregor Bainczyk , Rolf Nagel , Helmut Leininger , Rolf Lerch
发明人： Gregor Bainczyk , Rolf Nagel , Helmut Leininger , Rolf Lerch
IPC分类号： G01N110
CPC分类号： B01L3/5023 , B01L2200/18 , B01L2300/042 , B01L2300/0825 , B01L2300/0887 , B01L2300/105 , B01L2400/0406
摘要： The invention concerns a system for the storage and transport of sample material on absorbent material which is characterized in that the system contains no test reagents and it additionally includes a closable container containing a medium that can absorb moisture such as a desiccant in addition to the absorbent material for absorbing a liquid sample. Furthermore the system according to the invention can contain an agent to stabilize the sample material and optionally further auxiliary substances.
摘要翻译：本发明涉及一种用于在吸收材料上储存和运送样品材料的系统，其特征在于该系统不含测试试剂，并且还包括一种可封闭的容器，该容器包含除吸收剂之外还可以吸收湿气的介质，例如干燥剂用于吸收液体样品的材料。此外，根据本发明的系统可以含有用于稳定样品材料和任选的另外的辅助物质的试剂。

7. 发明授权

US6055060A Analytical system with means for detecting too small sample volumes 失效
标题翻译：具有检测太小样品量的手段的分析系统
公开(公告)号：US6055060A
公开(公告)日：2000-04-25
申请号：US895368
申请日：1997-07-16
申请人： Franz Bolduan , Bernd Eisenbarth , Karl Miltner , Helmut Leininger , Detlef Thym
发明人： Franz Bolduan , Bernd Eisenbarth , Karl Miltner , Helmut Leininger , Detlef Thym
IPC分类号： G01N31/22 , G01N21/27 , G01N21/86 , G01N33/487 , G01N33/52 , G01N35/00 , G01N35/02 , G01N35/10 , G01N21/00
CPC分类号： G01N21/8483 , G01N35/00029 , G01N35/00594 , G01N35/00603 , G01N2035/009 , G01N35/1016
摘要： Analytical system for evaluating test elements having means of determining whether a sufficient amount of sample liquid was evenly applied to an application zone comprising in a first embodiment of the invention at least two sources of light which illuminate separate or at least not fully overlapping areas of the application zone or the evaluation zone of the test strip, a control unit with which the light sources, of which there at least two, can be independently activated, at least one sensor which detects light reflected by the evaluation zone or transmitted by the evaluation zone and supplies an output signal proportional to the intensity of light as well as an evaluation unit which receives a first output signal from the sensor and converts it into a first measured value when the first of the light sources is activated, receives a second output signal from the sensor and converts it into a second measured value when the second of the light sources, is activated and compares the measured values and determines whether the deviation of the first value measured from the second value measured is sufficiently small. In a second embodiment of an analytical system according to the invention, at least one light source is used to illuminate the sample application zone or the evaluation zone of a test element and at least two sensors detect light reflected or transmitted by the evaluation zone, the output signal of the sensors being converted into measured values by the evaluation unit which determines whether the deviation of the measured values is sufficiently small.
摘要翻译：用于评估测试元件的分析系统，其具有确定足够量的样品液体是否均匀地施加到包括本发明的第一实施方案的施用区域中的装置，所述至少两个光源照射所述第一实施例的分离的或至少不完全重叠的区域应用区域或测试条的评估区域，控制单元，其中至少两个的光源可独立地被激活;至少一个传感器，其检测由评估区域反射或由评估区域传输的光并且提供与光强成正比的输出信号以及评估单元，该评估单元从第一传感器接收第一输出信号并将其转换为第一测量值，当第一光源被激活时，从第一测量值接收第二输出信号传感器并将其转换成第二个测量值，当第二个光源被激活并比较我并确定从测量的第二值测得的第一值的偏差是否足够小。在根据本发明的分析系统的第二实施例中，使用至少一个光源来照射测试元件的样品施加区域或评估区域，并且至少两个传感器检测由评估区域反射或透射的光，由评估单元将传感器的输出信号转换为测量值，该评估单元确定测量值的偏差是否足够小。

8. 发明授权

US08449823B2 Diagnostic tape unit 有权
标题翻译：诊断磁带机
公开(公告)号：US08449823B2
公开(公告)日：2013-05-28
申请号：US12940368
申请日：2010-11-05
申请人： Peter Seelig , Helmut Leininger
发明人： Peter Seelig , Helmut Leininger
IPC分类号： G01N33/00
CPC分类号： G01N21/55 , A61B5/14532 , A61B5/1455 , A61B2562/0295 , B01L3/505 , B01L9/523 , B01L2300/0654 , B01L2300/0812 , B01L2300/0825 , B01L2300/0841 , G01N21/8483 , G01N33/48764 , G01N33/66
摘要： The invention concerns a diagnostic tape unit with a test tape that can be wound onto a spool which comprises a transport tape and a plurality of test elements mounted thereon, where the test elements have an analytical reagent layer, a carrier foil supporting the reagent layer and a piece of adhesive tape connecting the carrier foil with the transport tape, and where the front side of the reagent layer facing away from the carrier foil is designed for the application of a sample substance. According to the invention it is proposed that the test elements in combination with the light transmitting transport tape in each case form an optical multi-layer system for a rear-side reflection-photometric measurement of the reagent layer.
摘要翻译：本发明涉及一种诊断带单元，其具有可以缠绕在卷轴上的测试带，该卷轴包括传送带和安装在其上的多个测试元件，其中测试元件具有分析试剂层，载体箔支撑试剂层，将载体箔与输送带连接的一段粘合带，并且试剂层的背离载体箔的前侧被设计用于施加样品物质。根据本发明，提出了与各透光性输送带组合的测试元件形成用于对试剂层进行背面反射测光的光学多层系统。

9. 发明授权

US06537496B1 Functional overlay for flexible objects in particular for diagnostic test strips 失效
标题翻译：灵活对象的功能覆盖，特别是诊断测试条
公开(公告)号：US06537496B1
公开(公告)日：2003-03-25
申请号：US09426938
申请日：1999-10-22
申请人： Wolfgang-Reinhold Knappe , Helmut Leininger , Ralf Steinbrueck , Franz Wittmann
发明人： Wolfgang-Reinhold Knappe , Helmut Leininger , Ralf Steinbrueck , Franz Wittmann
IPC分类号： G01N2100
CPC分类号： G01N33/525
摘要： A flat-shaped functional overlay for at least one region of a flat-shaped flexible object which does not form a fold when the sandwich composed of the flexible object and overlay is bent towards the side on which the overlay is located is described. The overlay is composed of one or several flat-shaped overlays which are attached to the flexible object in such a way that a part of their surface can move freely relative to the surface of the object covered by this part in the direction of curvature produced when the object is bent. In addition diagnostic test strips are described which have such an overlay.
摘要翻译：描述了当由柔性物体和覆盖层构成的夹层由朝向覆盖层所在的一侧弯曲时，平面状柔性物体的至少一个区域的平坦形功能覆盖层不会形成折痕。覆盖层由一个或多个平面形状的叠层组成，这些叠层以这样的方式附接到柔性物体上，使得其表面的一部分相对于被该部分覆盖的物体的表面在所产生的曲率方向上自由移动，物体被弯曲。此外，描述了具有这种覆盖层的诊断测试条。

10. 发明授权

US6025203A Diagnostic test carrier and methods in which it is used to determine an analyte 失效
标题翻译：诊断测试载体及其用于测定分析物的方法
公开(公告)号：US6025203A
公开(公告)日：2000-02-15
申请号：US897608
申请日：1997-07-21
申请人： Peter Vetter , Helmut Leininger
发明人： Peter Vetter , Helmut Leininger
IPC分类号： G01N31/22 , G01N33/52 , G01N33/48
CPC分类号： G01N33/525 , Y10T436/25375 , Y10T436/255
摘要： The invention concerns a diagnostic test carrier (1) containing a supporting layer (2) with a detection layer (3) arranged thereon containing the reagents required to determine an analyte in a liquid sample and a network (4) covering the detection layer (3) which is larger than the detection layer (3) and which is attached to the supporting layer (2), wherein the network (4) is a plied knitted fabric the threads of which are highly roughened on the side facing the detection layer (3) whereas the threads on the side of the knitted fabric which face away from the detection layer (3) are relatively smooth as well as the use of such a test carrier to determine an analyte in a liquid and the use of such a knitted fabric as a layer spreading liquid in a diagnostic test carrier. Moreover the invention concerns a method for the determination of an analyte in a liquid sample with the aid of a test carrier according to the invention.
摘要翻译：本发明涉及一种诊断测试载体（1），其包含支撑层（2），其上布置有检测层（3），其上包含确定液体样品中的分析物所需的试剂和覆盖检测层（3）的网络（4）），其大于所述检测层（3）并且附接到所述支撑层（2），其中所述网络（4）是其面线向所述检测层（3）侧的线被高度粗糙化的合股针织物），而针对织物的远离检测层（3）的那侧的线相对平滑，以及使用这种测试载体来确定液体中的分析物以及使用这样的针织物作为在诊断测试载体中铺展液体的层。此外，本发明涉及借助于根据本发明的测试载体来确定液体样品中的分析物的方法。

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