专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08900602B2 Disintegrating particle composition and orally rapidly disintegrating tablet 有权
标题翻译：崩解颗粒组合物和口服快速崩解片剂
公开(公告)号：US08900602B2
公开(公告)日：2014-12-02
申请号：US13389874
申请日：2010-08-11
申请人： Keiichi Fujiwara , Tadashi Fukami , Haruka Koizumi
发明人： Keiichi Fujiwara , Tadashi Fukami , Haruka Koizumi
IPC分类号： A23L1/48 , A61K47/26 , A61K9/20 , A61K31/5375 , A61K9/00
CPC分类号： A61K9/0056 , A61K9/2018 , A61K31/5375
摘要： Disclosed is an orally rapidly disintegrating tablet which has a good texture and taste in the oral cavity, such a sufficient hardness as not giving any worry of being chipped or dusted during production or transportation and good disintegrating properties in the oral cavity. The orally rapidly disintegrating tablet, which has a good texture and taste, an appropriate hardness, and good disintegrating properties, can be produced by using a composition, which is prepared by dispersing, by spray-drying, an inorganic excipient and starch(es) in complex particles composed of mannitol and xylitol, in an orally rapidly disintegrating tablet.
摘要翻译：公开了一种在口腔中具有良好质地和口感的口腔快速崩解片，足够的硬度，不会在生产或运输过程中担心切屑或粉尘，并且在口腔中具有良好的崩解性能。可以通过使用通过喷雾干燥分散无机赋形剂和淀粉而制备的组合物来制备具有良好的质地和味道，适当的硬度和良好的崩解性的口腔快速崩解片剂，在由甘露糖醇和木糖醇组成的复合颗粒中，在口腔快速崩解片剂中。

2. 发明申请

US20120165413A1 DISINTEGRATING PARTICLE COMPOSITION AND ORALLY RAPIDLY DISINTEGRATING TABLET 有权
标题翻译：消毒颗粒组合物和ORANDY快速消毒片
公开(公告)号：US20120165413A1
公开(公告)日：2012-06-28
申请号：US13389874
申请日：2010-08-11
申请人： Keiichi Fujiwara , Tadashi Fukami , Haruka Koizumi
发明人： Keiichi Fujiwara , Tadashi Fukami , Haruka Koizumi
IPC分类号： A61K47/26 , A23L1/48
CPC分类号： A61K9/0056 , A61K9/2018 , A61K31/5375
摘要： Disclosed is an orally rapidly disintegrating tablet which has a good texture and taste in the oral cavity, such a sufficient hardness as not giving any worry of being chipped or dusted during production or transportation and good disintegrating properties in the oral cavity. The orally rapidly disintegrating tablet, which has a good texture and taste, an appropriate hardness, and good disintegrating properties, can be produced by using a composition, which is prepared by dispersing, by spray-drying, an inorganic excipient and starch(es) in complex particles composed of mannitol and xylitol, in an orally rapidly disintegrating tablet.
摘要翻译：公开了一种在口腔中具有良好质地和口感的口腔快速崩解片，足够的硬度，不会在生产或运输过程中担心切屑或粉尘，并且在口腔中具有良好的崩解性能。可以通过使用通过喷雾干燥分散无机赋形剂和淀粉而制备的组合物来制备具有良好的质地和味道，适当的硬度和良好的崩解性的口腔快速崩解片剂，在由甘露糖醇和木糖醇组成的复合颗粒中，在口腔快速崩解片剂中。

3. 发明申请

US20120040001A1 DISINTEGRATING PARTICLE COMPOSITION AND RAPIDLY DISINTEGRATING COMPRESSION-MOLDED MATERIAL USED THE SAME 审中-公开
标题翻译：消毒颗粒组合物和快速消毒压缩模塑材料使用相同
公开(公告)号：US20120040001A1
公开(公告)日：2012-02-16
申请号：US13148999
申请日：2010-02-12
申请人： Haruka Koizumi , Tadashi Fukami , Hitoshi Machimura
发明人： Haruka Koizumi , Tadashi Fukami , Hitoshi Machimura
IPC分类号： A61K9/14
CPC分类号： A61K9/1652 , A61K9/0056 , A61K9/1694 , A61K9/2013
摘要： [Subject Matter]A rapidly disintegrating compression-molded material has been demanded, which exhibits good taking feeling and taste in the oral cavity, has a sufficient hardness for prevent the material from causing problems such as cracking or dusting during the preparation or distribution process, also has a good disintegrating property in the oral cavity, and can be taken in a large amount.[Means to Solve]A disintegrating particle composition is prepared by wet-granulating a starch, a water-soluble binding agent, and if needed a molding agent/an effective ingredient. By incorporating this disintegrating particle composition, a rapidly disintegrating compression-molded material can be prepared which has an excellent taking feeling, taste, hardness and disintegrating property and can be taken without limitation in quantity.
摘要翻译： [主题]需要快速崩解的压缩成型材料，其在口腔中表现出良好的摄取感和味道，具有足够的硬度以防止在制备或分配过程中材料引起诸如破裂或粉尘等问题，口腔也具有良好的崩解性，可以大量服用。 [解决方法]通过将淀粉，水溶性粘合剂和需要的成型剂/有效成分进行湿法成粒，制备崩解性颗粒组合物。通过引入该崩解性粒子组合物，可以制备具有优异的感觉，味道，硬度和崩解性的快速崩解的压缩成型材料，并且可以不限于数量。

4. 发明授权

US09446055B2 Disintegrating particle composition and orally rapidly disintegrating tablet 有权
标题翻译：崩解颗粒组合物和口服快速崩解片剂
公开(公告)号：US09446055B2
公开(公告)日：2016-09-20
申请号：US13389880
申请日：2010-08-11
申请人： Keiichi Fujiwara , Tadashi Fukami , Haruka Koizumi
发明人： Keiichi Fujiwara , Tadashi Fukami , Haruka Koizumi
IPC分类号： A61K47/26 , A61K31/167 , A61K9/14 , A61K31/616 , A61K9/00 , A61K9/20
CPC分类号： A61K31/616 , A61K9/0056 , A61K9/2018
摘要： There has been a need for an orally rapidly disintegrating tablet which has a good texture and taste in the oral cavity, such a sufficient hardness as not giving any worry of being chipped or dusted during production or transportation and good disintegrating properties in the oral cavity and can sustain a sufficient hardness even under humid conditions after opening. Disclosed are a disintegrating particle composition which is prepared by dispersing, in the presence of water, mannitol, xylitol, an inorganic excipient, a disintegrating agent and carmellose and drying, and an orally rapidly disintegrating tablet which comprises said disintegrating particle composition, an active substance and a disintegrating agent. The disintegrating tablet has a good texture and taste, an appropriate hardness and good disintegrating properties and can sustain a sufficient hardness under humid conditions.
摘要翻译：需要一种在口腔中具有良好质地和口感的口服快速崩解片剂，足够的硬度，不会在生产或运输过程中担心不会被切碎或撒粉，并且在口腔中具有良好的崩解性能，即使在开放后的潮湿条件下，也能维持足够的硬度。公开了通过在水，甘露糖醇，木糖醇，无机赋形剂，崩解剂和羧甲基纤维素和干燥剂的存在下分散而制备的崩解颗粒组合物，以及包含所述崩解颗粒组合物的口服快速崩解片剂，活性物质和崩解剂。崩解片具有良好的质地和味道，适当的硬度和良好的崩解性能，并能在潮湿条件下维持足够的硬度。

5. 发明申请

US20120156261A1 DISINTEGRATING PARTICLE COMPOSITION AND ORALLY RAPIDLY DISINTEGRATING TABLET 有权
标题翻译：消毒颗粒组合物和ORANDY快速消毒片
公开(公告)号：US20120156261A1
公开(公告)日：2012-06-21
申请号：US13389880
申请日：2010-08-11
申请人： Keiichi Fujiwara , Tadashi Fukami , Haruka Koizumi
发明人： Keiichi Fujiwara , Tadashi Fukami , Haruka Koizumi
IPC分类号： A61K47/26 , A61K31/167 , A61K9/14 , A61K31/616 , A61K47/02 , A61K47/34
CPC分类号： A61K31/616 , A61K9/0056 , A61K9/2018
摘要： There has been a need for an orally rapidly disintegrating tablet which has a good texture and taste in the oral cavity, such a sufficient hardness as not giving any worry of being chipped or dusted during production or transportation and good disintegrating properties in the oral cavity and can sustain a sufficient hardness even under humid conditions after opening. Disclosed are a disintegrating particle composition which is prepared by dispersing, in the presence of water, mannitol, xylitol, an inorganic excipient, a disintegrating agent and carmellose and drying, and an orally rapidly disintegrating tablet which comprises said disintegrating particle composition, an active substance and a disintegrating agent. The disintegrating tablet has a good texture and taste, an appropriate hardness and good disintegrating properties and can sustain a sufficient hardness under humid conditions.
摘要翻译：需要一种在口腔中具有良好的质地和口感的口服快速崩解片剂，足够的硬度，不会在生产或运输过程中担心不会被切碎或撒粉，并且在口腔中具有良好的崩解性能，即使在开放后的潮湿条件下，也能维持足够的硬度。公开了通过在水，甘露醇，木糖醇，无机赋形剂，崩解剂和羧甲基纤维素和干燥剂的存在下分散而制备的崩解颗粒组合物，以及包含所述崩解颗粒组合物的口服快速崩解片剂，活性物质和崩解剂。崩解片具有良好的质地和味道，适当的硬度和良好的崩解性能，并能在潮湿条件下维持足够的硬度。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式