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1. 发明授权

US07670550B2 Rapid sterilization system 有权
标题翻译：快速灭菌系统
公开(公告)号：US07670550B2
公开(公告)日：2010-03-02
申请号：US11093526
申请日：2005-03-30
申请人： Szu-Min Lin , Paul T. Jacobs , Jenn-Hann Wang , James P. Kohler , Richard Jed Kendall , Harold R. Williams , Robert Lukasik
发明人： Szu-Min Lin , Paul T. Jacobs , Jenn-Hann Wang , James P. Kohler , Richard Jed Kendall , Harold R. Williams , Robert Lukasik
IPC分类号： A61L2/20
CPC分类号： A61L2/24 , A61L2/208 , A61L2202/122 , A61L2202/14
摘要： A method of sterilizing an article includes placing the article into a chamber containing an inner atmosphere and exhausting the inner atmosphere to lower pressure in the chamber. Hydrogen peroxide vapor is present in the chamber during at least a portion of the step of exhausting the inner atmosphere. Exhaustion of the inner atmosphere is terminated and additional hydrogen peroxide is admitted into the chamber. Hydrogen peroxide vapor contacts the article for a sufficient period to effect sterilization of the article.
摘要翻译：对物品进行灭菌的方法包括将物品放置在含有内部气氛的室中并排出内部气氛以使室内的压力降低。在排气内部气氛的步骤的至少一部分期间，过氧化氢蒸汽存在于室中。内部气氛的耗尽终止，另外的过氧化氢进入腔室。过氧化氢蒸气与制品接触足够的时间以实现制品的灭菌。

2. 发明授权

US07452504B2 Sterilization/disinfection cycle control 有权
标题翻译：灭菌/消毒循环控制
公开(公告)号：US07452504B2
公开(公告)日：2008-11-18
申请号：US10856664
申请日：2004-05-28
申请人： Su-Syin S. Wu , James P. Kohler , Harold R. Williams
发明人： Su-Syin S. Wu , James P. Kohler , Harold R. Williams
IPC分类号： A61L2/20
CPC分类号： A61L2/208 , A61L2/20 , A61L2/24 , A61L2202/122 , A61L2202/14
摘要： A sterilizer includes a vacuum chamber, a source of vaporizable sterilant, a vacuum pump, and a control system. The control system is programmed to take one or more data inputs regarding the nature of the load, such as lumen length and diameter, and determine one or more parameters of the sterilization cycle based upon the inputs.
摘要翻译：灭菌器包括真空室，可蒸发消毒源，真空泵和控制系统。控制系统被编程为对负载的性质（例如管腔长度和直径）采取一个或多个数据输入，并且基于输入确定灭菌周期的一个或多个参数。

3. 发明授权

US07300637B2 Sterilization container kit 失效
标题翻译：灭菌容器套件
公开(公告)号：US07300637B2
公开(公告)日：2007-11-27
申请号：US10261214
申请日：2002-09-30
申请人： Szu-Min Lin , Harold R. Williams , Robert Lukasik
发明人： Szu-Min Lin , Harold R. Williams , Robert Lukasik
IPC分类号： A61L2/20
CPC分类号： A61L2/208 , A61L2/07 , A61L2/206 , A61L2/26 , A61L2202/122 , A61L2202/182 , A61L2202/24
摘要： A sterilization container holds instruments during a sterilization process. It has an enclosure with an opening into the enclosure and an adapter at the opening. Various inserts such as semi-permeable filters and blocking plates may be placed into the adapter.
摘要翻译：灭菌容器在灭菌过程中保持仪器。它有一个带有开口的外壳和开口处的适配器。可以将各种插入件例如半透过滤器和阻挡板放置在适配器中。

4. 发明授权

US07229591B2 Lumen sterilization device and method 失效
标题翻译：流明消毒装置及方法
公开(公告)号：US07229591B2
公开(公告)日：2007-06-12
申请号：US10160869
申请日：2002-05-31
申请人： Su-Syin S. Wu , Harold R. Williams , Nancy S. Chu , Hans Strobel , Szu-Min Lin , Henry K. Hui , Leslie A. Feldman
发明人： Su-Syin S. Wu , Harold R. Williams , Nancy S. Chu , Hans Strobel , Szu-Min Lin , Henry K. Hui , Leslie A. Feldman
IPC分类号： A61L2/00
CPC分类号： A61L2/186 , A61L2/208 , A61L2202/24
摘要： Devices and methods for sterilizing lumens involve a booster that is attached to the lumen. In preferred embodiments, the contact area between the lumen and the booster enhances the penetration of an antimicrobial agent to the contact area.
摘要翻译：用于灭菌腔的装置和方法涉及附着于内腔的增压器。在优选实施例中，内腔和助推器之间的接触面积增强了抗微生物剂渗透到接触区域。

5. 发明授权

US07179419B2 Method for sterilizing devices in a container 失效
标题翻译：对容器中的装置进行消毒的方法
公开(公告)号：US07179419B2
公开(公告)日：2007-02-20
申请号：US10284987
申请日：2002-10-31
申请人： Szu-Min Lin , Anthony Lemus , Harold R. Williams , Paul T. Jacobs , Tralance O. Addy , Jon M. Jacobs
发明人： Szu-Min Lin , Anthony Lemus , Harold R. Williams , Paul T. Jacobs , Tralance O. Addy , Jon M. Jacobs
IPC分类号： A61L2/20
CPC分类号： A61L2/208 , A61L2/14 , A61L2/16 , A61L2202/122 , A61L2202/14 , A61L2202/24
摘要： A method for sterilizing medical devices and similar instruments in diffusion-restricted containers is provided. The sterilization method includes placing a liquid solution containing vaporizable germicide such as hydrogen peroxide into the diffusion-restricted container and vaporizing the germicide. The containers can be attachable and detachable to a sterilization system, and used as a vacuum chamber. An attachable/detachable container containing an article to be sterilized can be nested with a second container, and the article and inside and outside of the inner container are sterilized. The sterile article inside the nested containers can be transported and the sterile inner container with the sterilized article can removed from the outer container and placed in a sterile environment without contaminating the sterile environment. The sterile article can then be removed from the sterile container and utilized. Alternatively, the sterilization method may include introducing germicide vapor into an attachable/detachable container.
摘要翻译：提供了一种在扩散限制容器中对医疗器械和类似仪器进行消毒的方法。灭菌方法包括将含有可蒸发的杀菌剂如过氧化氢的液体溶液放置在扩散限制容器中并使杀菌剂蒸发。容器可以安装和拆卸到灭菌系统，并用作真空室。容纳待灭菌物品的可装卸的容器可以嵌入第二容器，并且将内部容器的内部和外部消毒。嵌套容器内的无菌制品可以运输，具有灭菌制品的无菌内容器可以从外容器中取出并放置在无菌环境中，而不会污染无菌环境。然后将无菌制品从无菌容器中取出并使用。或者，灭菌方法可以包括将杀菌剂蒸气引入可附接/可拆卸的容器中。

6. 发明授权

US6106772A Injector impinger 失效
标题翻译：喷油器冲击器
公开(公告)号：US6106772A
公开(公告)日：2000-08-22
申请号：US103126
申请日：1998-06-23
申请人： James P. Kohler , Harold R. Williams
发明人： James P. Kohler , Harold R. Williams
IPC分类号： A61L2/14 , A61L2/20 , B01D45/08
CPC分类号： A61L2/208 , A61L2/14 , B01D45/08 , A61L2202/11 , A61L2202/24
摘要： A sterilizing system for receiving a stream of solid-stabilizer-containing fluid and sterilizing an article comprises a chamber for receiving the article and an injection assembly coupled to the chamber for generating and introducing a fluid jet into the chamber. The system particularly comprises an injector impinger for removing particulates and liquid droplets from the solid-stabilizer-containing fluid by causing a sudden change of the stream line direction of the fluid jet. The injector impinger is positioned between the injection assembly and the article, so that the fluid jet can not reach the article without first interacting with the injector impinger. A method for removing particulates from a solid-stabilizer-containing fluid in a sterilizing process comprises the steps of providing the fluid, vaporizing the fluid, forming a vapor stream from the vaporized fluid, and removing the particulates and the droplets from the vapor stream by causing a sudden change of direction of stream line of the vapor stream.
摘要翻译：用于接收含固体稳定剂的流体流并对物品灭菌的消毒系统包括用于接收物品的腔室和联接到腔室的注射组件，用于产生流体射流并将其引入腔室。该系统特别地包括用于通过使流体射流的流线方向突然变化来从含固体稳定剂的流体中除去微粒和液滴的喷射器撞击器。喷射器撞击器位于注射组件和制品之间，使得流体射流不会首先与喷射器撞击器相互作用而到达制品。在灭菌方法中从含固体稳定剂的流体中除去微粒的方法包括以下步骤：提供流体，蒸发流体，形成来自蒸发的流体的蒸汽流，以及通过以下步骤从蒸汽流中除去微粒和液滴：导致蒸气流的流线方向突然变化。

7. 发明授权

US5911950A Method of releasing gas or vapor from a solid material 失效
标题翻译：从固体材料中释放气体或蒸汽的方法
公开(公告)号：US5911950A
公开(公告)日：1999-06-15
申请号：US941384
申请日：1997-09-30
申请人： Xiaolan Chen , Paul Taylor Jacobs , Szu-Min Lin , Robert M. Spencer , Harold R. Williams
发明人： Xiaolan Chen , Paul Taylor Jacobs , Szu-Min Lin , Robert M. Spencer , Harold R. Williams
IPC分类号： A61L2/16 , A01N59/00 , A61L2/04 , A61L2/10 , A61L2/14 , A61L2/20 , A61L2/24 , A61L2/26 , B01J7/00 , B65D65/38 , B65D65/40 , B65D81/24 , C01B15/01 , C01B15/03 , C01B15/037 , C01B15/06 , C01B15/08 , C01B15/10 , C01B15/14 , C01B15/16 , C01D7/00 , C07D233/64
CPC分类号： A61L2/208 , A01N59/00 , A61L2/14 , A61L2/20 , A61L2/26 , C01B15/01 , C01B15/03 , C01B15/06 , C01B15/08 , C01B15/103 , C01B15/14 , C01B15/16 , A61L2202/122 , A61L2202/24 , Y10S261/65 , Y10T428/1352 , Y10T428/1355 , Y10T428/1359 , Y10T428/1376 , Y10T428/1379 , Y10T428/1383
摘要： A system to deliver gas/vapor from solid materials. Specifically, the delivery system for the use of gas or vapor released from a solid material, such as a non-aqueous/solid hydrogen peroxide complex. The system is comprised of a delivery system that is configured to receive a plurality of disks containing the solid material and provide these disks into an injector. The injector heats the disks to produce a gas or vapor that is then provided into a chamber. The sterilization process can be done by gas or vapor alone, or in combination with plasma or ultra violet radiation. In particular, a control system automatically induces the delivery system to provide the injector with a disk and then remove the disk once the injection sequence is complete.
摘要翻译：从固体材料输送气体/蒸汽的系统。具体地，用于使用从固体材料如非水/固体过氧化氢络合物释放的气体或蒸汽的输送系统。该系统包括配送系统，该配送系统被配置为接收包含固体材料的多个盘，并将这些盘提供到喷射器中。喷射器加热盘以产生气体或蒸气，然后将其提供到室中。灭菌过程可以通过单独的气体或蒸气，或与等离子体或紫外线辐射结合进行。特别地，控制系统自动地引导传送系统以向注射器提供磁盘，然后一旦注射顺序完成就移除磁盘。

8. 发明授权

US4909287A Fluid injection system 失效
标题翻译：流体注射系统
公开(公告)号：US4909287A
公开(公告)日：1990-03-20
申请号：US179786
申请日：1988-04-11
申请人： Harold R. Williams , Robert M. Spencer
发明人： Harold R. Williams , Robert M. Spencer
IPC分类号： A61L2/24 , G01F11/08
CPC分类号： A61L2/24 , G01F11/086
摘要： A cassette containing a group of sealed cells is used as a means for delivering doses of fluid to be injected into a sterilizing chamber. After the cassette is automatically positioned over a piercing mechanism, the cassette is moved downwardly so that a cell is pierced. Fluid is then forced out of the cell by pneumatic pressure into an injector valve, which opens in a manner which does not adversely affect a vacuum within the chamber.
摘要翻译：使用包含一组密封细胞的盒作为用于输送待注射到灭菌室中的剂量的装置。在盒被自动定位在穿刺机构上之后，盒子向下移动，使得电池被刺穿。然后将流体通过气动压力从电池中排出到注射器阀中，该注射器阀以不会不利地影响腔室内的真空的方式打开。

9. 外观设计

USD306066S Multi-dispenser cassette or the like for dispensing doses of sterilizing liquid 失效
公开(公告)号：USD306066S
公开(公告)日：1990-02-13
申请号：US320723
申请日：1989-03-08
申请人： Harold R. Williams , Charles W. Howlett
设计人： Harold R. Williams , Charles W. Howlett

10. 发明授权

US07807100B2 Sterilization system and method with temperature-controlled condensing surface 有权
标题翻译：具有温度控制冷凝面的灭菌系统和方法
公开(公告)号：US07807100B2
公开(公告)日：2010-10-05
申请号：US10403217
申请日：2003-03-31
申请人： Alfredo Choperena , Harold R. Williams , Szu-Min Lin , Robert Lukasik , Richard Jed Kendall , James P. Kohler
发明人： Alfredo Choperena , Harold R. Williams , Szu-Min Lin , Robert Lukasik , Richard Jed Kendall , James P. Kohler
IPC分类号： A61L9/00 , A61L2/08 , A61L2/00
CPC分类号： A61L2/208 , A61L2/14 , A61L2/186 , A61L2/24 , A61L2202/122 , A61L2202/14 , A61L2202/24 , H01L35/00 , H04J14/0227 , H04J14/0241 , H04J14/0284 , H04Q11/0062 , H04Q2011/0084 , H04Q2011/0086
摘要： A chemical vapor sterilization process is enhanced by concentrating a germicide via condensation and re-vaporization thereof, exploiting the difference between the vapor pressures of the germicide and its solvent to extract some of the solvent during the condensation process.
摘要翻译：通过冷凝和再蒸发浓缩杀菌剂来增强化学蒸气灭菌过程，利用杀菌剂及其溶剂的蒸气压之间的差异，在冷凝过程中提取一些溶剂。

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