专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08987307B2 3-amino-pyridines as GPBAR1 agonists 有权
标题翻译： 3-氨基 - 吡啶类作为GPBAR1激动剂
公开(公告)号：US08987307B2
公开(公告)日：2015-03-24
申请号：US13406572
申请日：2012-02-28
申请人： Caterina Bissantz , Henrietta Dehmlow , Shawn David Erickson , Prabha Saba Karnachi , Kyungjin Kim , Rainer E. Martin , Patrizio Mattei , Ulrike Obst Sander , Sherrie Lynn Pietranico-Cole , Hans Richter , Christoph Ullmer
发明人： Caterina Bissantz , Henrietta Dehmlow , Shawn David Erickson , Prabha Saba Karnachi , Kyungjin Kim , Rainer E. Martin , Patrizio Mattei , Ulrike Obst Sander , Sherrie Lynn Pietranico-Cole , Hans Richter , Christoph Ullmer
IPC分类号： A61K31/44 , C07D213/72 , C07D213/75 , C07D213/81 , C07D213/82 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/04 , C07D405/12 , C07D413/04 , C07D413/12 , C07D417/04 , C07D417/12 , C07D491/107
CPC分类号： C07D213/75 , C07D213/81 , C07D213/82 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/04 , C07D405/12 , C07D413/04 , C07D413/12 , C07D417/04 , C07D417/12 , C07D491/107
摘要： This invention relates to novel 3-aminopyridines of the formula wherein B1, B2 and R1 to R6 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and can be used as medicaments for the treatment of diseases such as type II diabetes.
摘要翻译：本发明涉及下式的新的3-氨基吡啶类，其中B1，B2和R1至R6如说明书和权利要求书中所定义，以及其药学上可接受的盐。这些化合物是GPBAR1激动剂，可用作治疗II型糖尿病等疾病的药物。

2. 发明授权

US08410662B2 Electric universal drive 有权
标题翻译：电动万能驱动
公开(公告)号：US08410662B2
公开(公告)日：2013-04-02
申请号：US13068203
申请日：2011-05-05
申请人： Hans Richter
发明人： Hans Richter
IPC分类号： H01L41/08
CPC分类号： H02N2/101 , F16D55/2245 , F16D65/54 , F16D2125/68 , H02N2/021
摘要： In a universal drive with a rotatable or linearly movable drive member and piezo actuators supported on a carrier for acting on a leg supported on the drive member and moving the leg in a high-frequency stepping sequence in a drive direction, wherein the carriers are jointly supported on a stator by a pretension member which biases them elastically toward the drive member via an elbow lever mechanism including a first elbow lever and at least a second elbow lever which are both connected to an actuator by a coupling member and this arrangement is such that, with the first elbow lever stretched, the second elbow lever is kinked and vice versa.
摘要翻译：在具有可旋转或可线性移动的驱动构件的通用驱动器和支撑在载体上的压电致动器用于作用在支撑在驱动构件上的腿上并以驱动方向的高频步进顺序移动腿，其中载体共同通过预紧构件支撑在定子上，该预紧构件通过包括第一肘杆和至少第二肘杆的肘杆机构朝向驱动构件弹性地偏压，所述肘杆机构都通过联接构件连接到致动器，并且这种布置使得第一肘杆拉伸，第二肘杆扭结，反之亦然。

3. 发明授权

US08309734B2 Substituted pyridines as GPBAR1 agonists 有权
标题翻译：取代的吡啶作为GPBAR1激动剂
公开(公告)号：US08309734B2
公开(公告)日：2012-11-13
申请号：US12581227
申请日：2009-10-19
申请人： Caterina Bissantz , Henrietta Dehmlow , Rainer E. Martin , Ulrike Obst Sander , Hans Richter , Christoph Ullmer
发明人： Caterina Bissantz , Henrietta Dehmlow , Rainer E. Martin , Ulrike Obst Sander , Hans Richter , Christoph Ullmer
IPC分类号： C07D213/63
CPC分类号： C07D209/08 , C07C235/64 , C07D213/81 , C07D213/82 , C07D215/08 , C07D215/18 , C07D241/42 , C07D265/36 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/14 , C07D413/06 , C07D417/06 , C07D471/04 , C07D487/04
摘要： This invention relates to novel phenyl amide or pyridyl amide derivatives of the formula wherein A1, A2, B1, B2 and R1 to R11 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and can be used as medicaments for the treatment of diseases such as type II diabetes.
摘要翻译：本发明涉及下式的新型苯基酰胺或吡啶基酰胺衍生物，其中A1，A2，B1，B2和R1至R11如说明书和权利要求书中所定义，以及其药学上可接受的盐。这些化合物是GPBAR1激动剂，可用作治疗II型糖尿病等疾病的药物。

4. 发明授权

US08309581B2 Benzimidazole derivatives 有权
标题翻译：苯并咪唑衍生物
公开(公告)号：US08309581B2
公开(公告)日：2012-11-13
申请号：US12885588
申请日：2010-09-20
申请人： Gregory Martin Benson , Konrad Bleicher , Song Feng , Uwe Grether , Bernd Kuhn , Rainer E. Martin , Jean-Marc Plancher , Hans Richter , Markus Rudolph , Sven Taylor
发明人： Gregory Martin Benson , Konrad Bleicher , Song Feng , Uwe Grether , Bernd Kuhn , Rainer E. Martin , Jean-Marc Plancher , Hans Richter , Markus Rudolph , Sven Taylor
IPC分类号： A61K31/4439 , A61K31/4184 , C07D401/04 , C07D235/18 , C07D403/12 , A61P3/06
CPC分类号： C07D401/04 , C07D235/18 , C07D403/10 , C07D403/12 , C07D405/14 , C07D417/14
摘要： The present invention relates to compounds of formula (I), as well as pharmaceutically acceptable salts thereof can be used in the form of pharmaceutical compositions, wherein A, B, R1, R2, R3, R4, R5, n, m and p have the significance defined herein.
摘要翻译：本发明涉及式（I）化合物及其药学上可接受的盐可以药物组合物的形式使用，其中A，B，R 1，R 2，R 3，R 4，R 5，n，m和p具有本文定义的意义。

5. 发明授权

US08252826B2 Cyclopentyl- and cycloheptylpyrazoles 有权
标题翻译：环戊基 - 和环庚基吡唑
公开(公告)号：US08252826B2
公开(公告)日：2012-08-28
申请号：US13050031
申请日：2011-03-17
申请人： Gregory Martin Benson , Konrad Bleicher , Uwe Grether , Bernd Kuhn , Hans Richter , Sven Taylor
发明人： Gregory Martin Benson , Konrad Bleicher , Uwe Grether , Bernd Kuhn , Hans Richter , Sven Taylor
IPC分类号： A61K31/41 , A61K31/415 , C07D257/02 , C07D231/10
CPC分类号： C07D231/54 , A61K9/0019 , A61K9/0095 , A61K9/1623 , A61K9/1652 , A61K9/2018 , A61K9/2866 , A61K9/4825 , A61K9/4858 , C07D401/12 , C07D403/12
摘要： This invention relates to novel cyclopentyl- and cycloheptylpyrazole derivatives of the formula I wherein A and R1 to R4 are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. The invention relates also to compositions including these compounds and methods of using the compounds.
摘要翻译：本发明涉及式I的新的环戊基 - 和环庚基吡唑衍生物，其中A和R 1至R 4如说明书和权利要求书中所定义，以及其生理上可接受的盐。本发明还涉及包括这些化合物的组合物和使用该化合物的方法。

6. 发明授权

US08088930B2 Benzimidazole derivatives 有权
标题翻译：苯并咪唑衍生物
公开(公告)号：US08088930B2
公开(公告)日：2012-01-03
申请号：US12554023
申请日：2009-09-04
申请人： Gregory Martin Benson , Konrad Bleicher , Song Feng , Uwe Grether , Bernd Kuhn , Rainer E. Martin , Jean-Marc Plancher , Hans Richter , Sven Taylor
发明人： Gregory Martin Benson , Konrad Bleicher , Song Feng , Uwe Grether , Bernd Kuhn , Rainer E. Martin , Jean-Marc Plancher , Hans Richter , Sven Taylor
IPC分类号： A61K31/4184 , C07D235/12
CPC分类号： C07D235/18 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D495/04
摘要： The invention is concerned with novel benzimidazole derivatives of formula (I) wherein A, n and R1 to R7 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds can be used as medicaments.
摘要翻译：本发明涉及新的式（I）的苯并咪唑衍生物，其中A，n和R 1至R 7如说明书和权利要求书中所定义，以及其生理上可接受的盐和酯。这些化合物可以用作药物。

7. 发明授权

US07825258B2 Methyl-benzimidazole derivatives 有权
标题翻译：甲基 - 苯并咪唑衍生物
公开(公告)号：US07825258B2
公开(公告)日：2010-11-02
申请号：US12265049
申请日：2008-11-05
申请人： Gregory Martin Benson , Konrad Bleicher , Uwe Grether , Rainer E. Martin , Jean-Marc Plancher , Hans Richter , Sven Taylor , Minmin Yang
发明人： Gregory Martin Benson , Konrad Bleicher , Uwe Grether , Rainer E. Martin , Jean-Marc Plancher , Hans Richter , Sven Taylor , Minmin Yang
IPC分类号： A61K31/4184 , C07D235/06
CPC分类号： C07D235/06 , C07D405/12 , C07D409/12
摘要： The invention is concerned with novel substituted benzimidazole derivatives of formula (I) wherein R1 to R10 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds can be used as medicaments.
摘要翻译：本发明涉及式（I）的新型取代的苯并咪唑衍生物，其中R 1至R 10如说明书和权利要求书中所定义，以及其生理学上可接受的盐和酯。这些化合物可以用作药物。

8. 发明授权

US07723325B2 5-amido-indole-2-carboxamide derivatives 失效
标题翻译： 5-氨基 - 吲哚-2-甲酰胺衍生物
公开(公告)号：US07723325B2
公开(公告)日：2010-05-25
申请号：US12493516
申请日：2009-06-29
申请人： Matthias Nettekoven , Jean-Marc Plancher , Hans Richter , Olivier Roche , Sven Taylor
发明人： Matthias Nettekoven , Jean-Marc Plancher , Hans Richter , Olivier Roche , Sven Taylor
IPC分类号： A61K31/4439 , A61K31/5355 , A61K31/541 , C07D295/192 , C07D401/14 , C07D413/14
CPC分类号： C07D401/06 , C07D209/42 , C07D401/14 , C07D403/06 , C07D405/12 , C07D487/04 , C07D491/113
摘要： The present invention relates to compounds of formula I wherein G and R1 to R5 and R12 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prevention of diseases which are associated with the modulation of H3 receptors.
摘要翻译：本发明涉及式I化合物，其中G和R 1至R 5和R 12如说明书和权利要求书中所定义，及其药学上可接受的盐。该化合物可用于治疗和/或预防与H3受体的调节相关的疾病。

9. 发明申请

US20100105906A1 NOVEL PHENYL AMIDE OR PYRIDYL AMIDE DERIVATIVES 有权
标题翻译：新颖的苯胺或吡啶衍生物
公开(公告)号：US20100105906A1
公开(公告)日：2010-04-29
申请号：US12581227
申请日：2009-10-19
申请人： Caterina Bissantz , Henrietta Dehmlow , Rainer E. Martin , Ulrike Obst Sander , Hans Richter , Christoph Ullmer
发明人： Caterina Bissantz , Henrietta Dehmlow , Rainer E. Martin , Ulrike Obst Sander , Hans Richter , Christoph Ullmer
IPC分类号： C07D241/38
CPC分类号： C07D209/08 , C07C235/64 , C07D213/81 , C07D213/82 , C07D215/08 , C07D215/18 , C07D241/42 , C07D265/36 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/14 , C07D413/06 , C07D417/06 , C07D471/04 , C07D487/04
摘要： This invention relates to novel phenyl amide or pyridyl amide derivatives of the formula wherein A1, A2, B1, B2 and R1 to R11 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and can be used as medicaments for the treatment of diseases such as type II diabetes.
摘要翻译：本发明涉及下式的新型苯基酰胺或吡啶基酰胺衍生物，其中A1，A2，B1，B2和R1至R11如说明书和权利要求书中所定义，以及其药学上可接受的盐。这些化合物是GPBAR1激动剂，可用作治疗II型糖尿病等疾病的药物。

10. 发明申请

US20100093818A1 BENZIMIDAZOLE DERIVATIVES 失效
标题翻译：苯并咪唑衍生物
公开(公告)号：US20100093818A1
公开(公告)日：2010-04-15
申请号：US12577765
申请日：2009-10-13
申请人： Gregory Martin Benson , Konrad Bleicher , Song Feng , Uwe Grether , Bernd Kuhn , Rainer E. Martin , Jean-Marc Plancher , Hans Richter , Sven Taylor
发明人： Gregory Martin Benson , Konrad Bleicher , Song Feng , Uwe Grether , Bernd Kuhn , Rainer E. Martin , Jean-Marc Plancher , Hans Richter , Sven Taylor
IPC分类号： A61K31/4184 , C07D235/12 , A61P9/00 , A61P9/10 , A61P35/00 , A61P17/06 , A61P25/00 , A61P25/28 , A61P25/16 , A61P3/10 , A61P3/06
CPC分类号： C07D235/18
摘要： The invention is concerned with novel benzimidazole derivatives of formula (I) wherein R1 to R6 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds can be used as medicaments.
摘要翻译：本发明涉及式（I）的新的苯并咪唑衍生物，其中R 1至R 6如在说明书和权利要求书中所定义，以及其生理上可接受的盐和酯。这些化合物可以用作药物。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式