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1. 发明授权

US08639742B2 Refreshing cached documents and storing differential document content 有权
标题翻译：刷新缓存的文档并存储差异文档内容
公开(公告)号：US08639742B2
公开(公告)日：2014-01-28
申请号：US13550540
申请日：2012-07-16
申请人： Eric Russell Fredricksen , Hanping Feng , Naga Sridhar Kataru , Georges Harik
发明人： Eric Russell Fredricksen , Hanping Feng , Naga Sridhar Kataru , Georges Harik
IPC分类号： G06F15/16
CPC分类号： H04L67/1097 , H04L29/08729 , H04L67/02 , H04L67/32
摘要： The present invention is directed to a method for updating a cache. A server identifies whether certain preconditions have been met for a document in a cache from freshness parameters associated with a document identifier for the document. Then when the preconditions have been met, a first document content is retrieved from a remote host. A first content fingerprint for the first document content is calculated. The first document content is stored in the cache. Then a content difference is calculated between the first document content and a second document content, both associated with the document identifier. The content difference is stored. Then the document identifier is associated with the content difference.
摘要翻译：本发明涉及一种用于更新高速缓存的方法。服务器识别与文档的文档标识符相关联的新鲜度参数是否满足高速缓存中的文档的某些前提条件。然后当满足前提条件时，从远程主机检索第一个文档内容。计算第一文档内容的第一内容指纹。第一个文档内容存储在缓存中。然后，在与文档标识符相关联的第一文档内容和第二文档内容之间计算内容差异。存储内容差异。然后文档标识符与内容差异相关联。

2. 发明申请

US20130185054A1 TECHNIQUES FOR INSERTING DIACRITICAL MARKS TO TEXT INPUT VIA A USER DEVICE 有权
标题翻译：通过用户设备将双向标记插入文本输入的技术
公开(公告)号：US20130185054A1
公开(公告)日：2013-07-18
申请号：US13565056
申请日：2012-08-02
申请人： Xiangye Xiao , Yuanbo Zhang , Vincent Ngo Bao Khoi , Fan Yang , Baohua Liao , Hanping Feng
发明人： Xiangye Xiao , Yuanbo Zhang , Vincent Ngo Bao Khoi , Fan Yang , Baohua Liao , Hanping Feng
IPC分类号： G06F17/27
CPC分类号： G06F17/214 , G06F3/018 , G06F17/2223 , G06F17/276
摘要： A computer-implemented method for assisting a user to input Vietnamese text to a user device lacking a subset of characters in a Vietnamese alphabet includes receiving a character input by a user, determining three words previously input by the user, the three words having already had diacritical marks inserted, transmitting the three words and the character to a server via a network, receiving first and second information corresponding to the character from the server via the network, the first and second information generated at the server based on a context of the three words, the context determined at the server using a language model, the first and second information indicating whether the character requires a diacritical mark and a specific diacritical mark, respectively, generating a modified character comprising a character in the Vietnamese alphabet based on the character and the first and second information, and displaying the modified character.
摘要翻译：用于辅助用户将越南语文本输入到越南字母中缺少字符子集的用户设备的计算机实现的方法包括：接收用户输入的字符，确定用户先前输入的三个字，已经有三个字插入的变音标记，经由网络将三个字和字符发送到服务器，经由网络从服务器接收对应于该字符的第一和第二信息，基于三个上下文的服务器生成的第一和第二信息单词，使用语言模型在服务器处确定的上下文，分别指示角色是否需要变音标记和特定变音符号的第一和第二信息，生成包括基于字符的越南字母表中的字符的修改字符;以及第一和第二信息，并显示修改的字符。

3. 发明申请

US20130013636A1 METHOD AND SYSTEM FOR PROCESSING QUERIES INITIATED BY USERS OF MOBILE DEVICES 有权
标题翻译：用于处理由移动设备的用户启动的查询的方法和系统
公开(公告)号：US20130013636A1
公开(公告)日：2013-01-10
申请号：US13619872
申请日：2012-09-14
申请人： Benjamin C. Ling , Jie J. Wu , Jian Gong Deng , Hanping Feng
发明人： Benjamin C. Ling , Jie J. Wu , Jian Gong Deng , Hanping Feng
IPC分类号： G06F17/30
CPC分类号： G06F17/30867 , G06F17/30979 , G06F17/30991 , H04L51/066 , H04W4/14 , H04W48/16
摘要： In one embodiment, a method for processing queries initiated by users of mobile devices includes receiving an incoming message containing a query initiated by a user of a mobile device, and extracting the query from the received message. The message further includes obtaining a result of the query and creating an outgoing message with the result of the query for delivery to the mobile device.
摘要翻译：在一个实施例中，用于处理由移动设备的用户发起的查询的方法包括：接收包含由移动设备的用户发起的查询的输入消息，以及从接收到的消息中提取查询。该消息还包括获得查询的结果并创建具有用于传送到移动设备的查询结果的传出消息。

4. 发明申请

US20120173222A1 METHOD AND SYSTEM FOR FACILITATING TEXT INPUT 有权
标题翻译：促进文本输入的方法和系统
公开(公告)号：US20120173222A1
公开(公告)日：2012-07-05
申请号：US13142898
申请日：2011-01-05
申请人： Yonggang Wang , Xiangye Xiao , Junyu Wang , Jian Zeng , Pan Jie , George Zhang , Annie Chang , Hanping Feng , Henry Ou
发明人： Yonggang Wang , Xiangye Xiao , Junyu Wang , Jian Zeng , Pan Jie , George Zhang , Annie Chang , Hanping Feng , Henry Ou
IPC分类号： G06F3/048 , G06F17/28 , G06F17/20
CPC分类号： G06F17/273 , G06F17/276 , G06F17/289
摘要： A method and system for facilitating text input is disclosed. The method comprises: invoking an input assistant from within an application in an operating environment at a client, the input assistant being a standalone input service within the same operating environment as the application, receiving a text string from a user in an input field of the application, providing, by the input assistant, input prediction for completing the text string, selecting an input text of at least one word in the input field of the application, retrieving, by the input assistant, text content related to the input text from one or more text assistance services in communication with the input assistant, presenting the received text content to the user for assistance in the user's text input.
摘要翻译：公开了一种便于文本输入的方法和系统。该方法包括：在客户端的操作环境中从应用程序内调用输入助手，输入助理是在与应用程序相同的操作环境内的独立输入服务，在用户的输入字段中接收来自用户的文本串应用程序，由输入助理提供用于完成文本串的输入预测，在应用的输入字段中选择至少一个单词的输入文本，由输入助理检索与一个输入文本相关的文本内容或更多的与输入助理通信的文本辅助服务，将接收的文本内容呈现给用户以帮助用户的文本输入。

5. 发明授权

US10961299B2 Tetra-specific, octameric binding agents and antibodies against Clostridium difficile toxin A and toxin B for treatment of C. difficile infection 有权
公开(公告)号：US10961299B2
公开(公告)日：2021-03-30
申请号：US15548901
申请日：2016-02-05
申请人： Hanping Feng , Yongjun Guan , Yongrong Zhang , Zhiyong Yang , Lianfa Shi
发明人： Hanping Feng , Yongjun Guan , Yongrong Zhang , Zhiyong Yang , Lianfa Shi
IPC分类号： C07K16/12 , A61P31/04 , A61K39/00
摘要： Novel, antibody-based binding agents derived from human and camelid immunoglobulins are described. These binding agents recognize and bind with specificity to Clostridium difficile toxin A and/or toxin B and in some cases exhibit toxin neutralizing activity. These binding agents can be used to treat or prevent primary and recurrent CDI. The binding agents include camelid VHH peptide monomers, linked groups of VHH peptide monomers, VHH peptide monomers joined to antibody Fc domains, and VHH peptide monomers joined to IgG antibodies.

6. 发明授权

US08306511B2 Method and system for processing queries initiated by users of mobile devices 有权
标题翻译：用于处理由移动设备的用户发起的查询的方法和系统
公开(公告)号：US08306511B2
公开(公告)日：2012-11-06
申请号：US12652646
申请日：2010-01-05
申请人： Benjamin C. Ling , Jie J. Wu , Jian Gong Deng , Hanping Feng
发明人： Benjamin C. Ling , Jie J. Wu , Jian Gong Deng , Hanping Feng
IPC分类号： H04W3/42
CPC分类号： G06F17/30867 , G06F17/30979 , G06F17/30991 , H04L51/066 , H04W4/14 , H04W48/16
摘要： In one embodiment, a method for processing queries initiated by users of mobile devices includes receiving an incoming message containing a query initiated by a user of a mobile device, and extracting the query from the received message. The message further includes obtaining a result of the query and creating an outgoing message with the result of the query for delivery to the mobile device.
摘要翻译：在一个实施例中，用于处理由移动设备的用户发起的查询的方法包括：接收包含由移动设备的用户发起的查询的输入消息，以及从接收到的消息中提取查询。该消息还包括获得查询的结果并创建具有用于传送到移动设备的查询结果的传出消息。

7. 发明授权

US07643822B2 Method and system for processing queries initiated by users of mobile devices 有权
标题翻译：用于处理由移动设备的用户发起的查询的方法和系统
公开(公告)号：US07643822B2
公开(公告)日：2010-01-05
申请号：US10957115
申请日：2004-09-30
申请人： Benjamin C. Ling , Jie J. Wu , Jian Gong Deng , Hanping Feng
发明人： Benjamin C. Ling , Jie J. Wu , Jian Gong Deng , Hanping Feng
IPC分类号： H04L29/06 , H04M3/42 , H04W4/00 , H04M1/725
CPC分类号： G06F17/30867 , G06F17/30979 , G06F17/30991 , H04L51/066 , H04W4/14 , H04W48/16
摘要： In one embodiment, a method for processing queries initiated by users of mobile devices includes receiving an incoming message containing a query initiated be a user of a mobile device, and extracting the query from the received message. The message further includes obtaining a result of the query and creating an outgoing message with the result of the query for delivery to the mobile device.
摘要翻译：在一个实施例中，用于处理由移动设备的用户发起的查询的方法包括：接收包含作为移动设备的用户的发起的查询的传入消息，以及从所接收的消息中提取查询。该消息还包括获得查询的结果并创建具有用于传送到移动设备的查询结果的传出消息。

8. 发明授权

US12077575B2 Humanized tetra-specific octavalent antibody against clostridium difficile toxin A and B 有权
公开(公告)号：US12077575B2
公开(公告)日：2024-09-03
申请号：US17616134
申请日：2020-06-03
申请人： Hanping Feng , Yongrong Zhang , Zhiyong Yang , Hua Yu , Yifan Zhang
发明人： Hanping Feng , Yongrong Zhang , Zhiyong Yang , Hua Yu , Yifan Zhang
IPC分类号： C07K16/12 , A61K39/00 , A61P31/04
CPC分类号： C07K16/1282 , A61P31/04 , A61K2039/505 , C07K2317/22 , C07K2317/24
摘要： Novel, antibody-based binding agents derived from camelid VHH and human immunoglobulins are described. These binding agents recognize and bind with specificity to Clostridium difficile toxin A and/or toxin B and in some cases exhibit toxin neutralizing activity. These binding agents can be used to treat or prevent primary and recurrent CDI. The binding agents include humanized VHH peptide monomers, linked groups of humanized VHH peptide monomers, humanized VHH peptide monomers joined to antibody Fc domains, and humanized VHH peptide monomers joined to IgG antibodies.

9. 发明公开

US20230340087A1 YEAST-BASED IMMUNOTHERAPY AGAINST CLOSTRIDIUM DIFFICILE INFECTION 审中-公开
公开(公告)号：US20230340087A1
公开(公告)日：2023-10-26
申请号：US17955537
申请日：2022-09-29
申请人： Hanping Feng , James Eugene GALEN , Kevin CHEN , Yixuan ZHU
发明人： Hanping Feng , James Eugene GALEN , Kevin CHEN , Yixuan ZHU
IPC分类号： C07K16/12 , A61P31/04 , A61K9/00 , A61K36/064 , A61K45/06 , C12N1/18 , G01N33/569
CPC分类号： C07K16/1282 , A61P31/04 , A61K9/0031 , A61K9/0043 , A61K9/0053 , A61K36/064 , A61K45/06 , C12N1/18 , G01N33/56961 , A61K2039/505
摘要： Antibody-based binding agents derived from human and camelid immunoglobulins are described, as well as strains of yeast engineered to secrete the binding agents, and methods of treating and preventing Clostridium difficile infections using the engineered strains of yeast. These binding agents recognize and bind with specificity to Clostridium difficile toxin A and/or toxin B and in some cases exhibit toxin neutralizing activity. The binding agents include camelid VHH peptide monomers, linked groups of VHH peptide monomers, VHH peptide monomers joined to antibody Fc domains, and VHH peptide monomers joined to IgG antibodies.

10. 发明申请

US20190111001A1 MICROPARTICULATE SYSTEM FOR COLONIC DRUG DELIVERY 审中-公开
公开(公告)号：US20190111001A1
公开(公告)日：2019-04-18
申请号：US16089564
申请日：2017-03-30
申请人： Hanping FENG , Hua YU , Stephen HOAG , Bowen JIANG
发明人： Hanping FENG , Hua YU , Stephen HOAG , Bowen JIANG
IPC分类号： A61K9/50 , C07K16/12 , A61K39/40 , A61P31/04
摘要： A delivery system that allows for targeted released of therapeutics in selected regions of the GI tract is provided. The delivery system is adapted to deliver a certain type of therapeutic, such as a protein-based therapeutic, to a certain area of the GI tract, such the colon of a subject. The delivery vehicle comprises a microbead coated with layers that include: a subcoat layer and a therapeutic agent layer. The delivery vehicles may also include an enteric coating layer and/or a sustained release layer.

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