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1. 发明申请

US20120051667A1 METHOD AND SYSTEM OF RECONSTRUCTING SUPER-RESOLUTION IMAGE 有权
标题翻译：重构超分辨率图像的方法和系统
公开(公告)号：US20120051667A1
公开(公告)日：2012-03-01
申请号：US13185810
申请日：2011-07-19
申请人： Bong-hyup KANG , Han-seok KO , Tae-yup SONG , Bon-hwa KU , Young-hyun LEE , Min-jae KIM , Dae-sung CHUNG , Hyun-hak SHIN
发明人： Bong-hyup KANG , Han-seok KO , Tae-yup SONG , Bon-hwa KU , Young-hyun LEE , Min-jae KIM , Dae-sung CHUNG , Hyun-hak SHIN
IPC分类号： G06K9/32
CPC分类号： G06T3/4053
摘要： A method and system of generating a super-resolution image is provided. fusing The method includes inputting an image; and generating an estimated high-resolution image of a current time by fusing an input image and an estimated high-resolution image of a previous time corresponding to the input image.
摘要翻译：提供了一种生成超分辨率图像的方法和系统。融合方法包括输入图像; 以及通过融合输入图像和对应于输入图像的前一时间的估计高分辨率图像来生成估计的当前时间的高分辨率图像。

2. 发明申请

US20090304200A1 Adaptive mode control apparatus and method for adaptive beamforming based on detection of user direction sound 有权
标题翻译：基于用户方向声音检测的自适应波束成形自适应模式控制装置及方法
公开(公告)号：US20090304200A1
公开(公告)日：2009-12-10
申请号：US12455873
申请日：2009-06-09
申请人： Hyun-Soo Kim , Han-Seok Ko , Joung-Hoon Beh , Taek-Jin Lee
发明人： Hyun-Soo Kim , Han-Seok Ko , Joung-Hoon Beh , Taek-Jin Lee
IPC分类号： G10K11/16
CPC分类号： G10K11/178 , G10K2210/111
摘要： An adaptive mode control apparatus and method for adaptive beamforming based on detection of a user direction sound are provided. The adaptive mode control apparatus includes a signal intensity detector that searches for signal intensity of each designated direction to detect signal intensity having a maximum value when a voice signal of each direction is input through at least one microphone; and an adaptive mode controller that compares the signal intensity having the maximum value detected through the signal intensity detector with a threshold value and determines whether to perform an adaptive mode of a Generalized Sidelobe Canceller (GSC) according to the comparison results. Therefore, a lack of control of adaptation of an adaptive filter of the conventional art is solved. That is, as one condition for guaranteeing performance of adaptive beamforming, adaptation of an adaptive filter is not performed when noise of a sound with a high autocorrelation is cancelled.
摘要翻译：提供了一种基于用户方向声音检测的自适应波束成形的自适应模式控制装置和方法。自适应模式控制装置包括信号强度检测器，当通过至少一个麦克风输入每个方向的语音信号时，搜索每个指定方向的信号强度以检测具有最大值的信号强度; 以及自适应模式控制器，其将具有通过信号强度检测器检测到的最大值的信号强度与阈值进行比较，并且根据比较结果确定是否执行广义旁瓣消除器（GSC）的自适应模式。因此，解决了传统技术的自适应滤波器的适应性缺乏控制。也就是说，作为用于保证自适应波束形成的性能的一个条件，当取消具有高自相关性的声音的噪声时，不执行自适应滤波器的自适应。

3. 发明授权

US08682109B2 Method and system of reconstructing super-resolution image 有权
标题翻译：重构超分辨率图像的方法和系统
公开(公告)号：US08682109B2
公开(公告)日：2014-03-25
申请号：US13185810
申请日：2011-07-19
申请人： Bong-hyup Kang , Han-seok Ko , Tae-yup Song , Bon-hwa Ku , Young-hyun Lee , Min-jae Kim , Dae-sung Chung , Hyun-hak Shin
发明人： Bong-hyup Kang , Han-seok Ko , Tae-yup Song , Bon-hwa Ku , Young-hyun Lee , Min-jae Kim , Dae-sung Chung , Hyun-hak Shin
IPC分类号： G06K9/32 , G09G5/02
CPC分类号： G06T3/4053
摘要： A method and system of generating a super-resolution image is provided. fusing The method includes inputting an image; and generating an estimated high-resolution image of a current time by fusing an input image and an estimated high-resolution image of a previous time corresponding to the input image.
摘要翻译：提供了一种生成超分辨率图像的方法和系统。融合方法包括输入图像; 以及通过融合输入图像和对应于输入图像的前一时间的估计高分辨率图像来生成估计的当前时间的高分辨率图像。

4. 发明授权

US08603994B2 Transcriptional repression leading to Parkinson's disease 有权
标题翻译：转录抑制导致帕金森病
公开(公告)号：US08603994B2
公开(公告)日：2013-12-10
申请号：US13294909
申请日：2011-11-11
申请人： Ted M. Dawson , Valina L. Dawson , Han Seok Ko , Jooho Shin
发明人： Ted M. Dawson , Valina L. Dawson , Han Seok Ko , Jooho Shin
IPC分类号： C12N15/11 , A61K48/00 , C07H21/02 , C07H21/04
CPC分类号： G01N33/6896 , A61K31/7088 , C12N15/113 , C12N15/1137 , C12N2310/14 , C12N2310/531 , C12N2320/30 , C12Q1/6883 , C12Q2600/158 , C12Y603/02019 , G01N33/6872 , G01N2333/4704 , G01N2800/2835
摘要： Parkinson's disease is caused by the preferential loss of substantia nigra dopamine neurons. A Parkin Interacting Substrate, PARIS (ZNF746) is identified. The levels of PARIS are regulated by the ubiquitin proteasome system via binding to and ubiquitination by the E3 ubiquitin ligase, parkin. PARIS is a KRAB and zinc finger protein that accumulates in models of parkin inactivation and in human brain Parkinson's disease patients. PARIS represses the expression of the transcriptional co-activator, PGC-1α and the PGC-1α target gene, NRF-1 by binding to insulin response sequences in the PGC-1α promoter. Conditional knockout of parkin in adult animals leads to progressive loss of dopamine (DA) neurons that is PARIS dependent. Overexpression of PARIS causes selective loss of DA neurons in the substantia nigra, which is reversed by either parkin or PGC-1α co-expression. The identification of PARIS provides a molecular mechanism for neurodegeneration due to parkin inactivation.
摘要翻译：帕金森病由黑质多巴胺神经元的优先丧失引起。确定了帕金相互作用基板，巴黎（ZNF746）。 PARIS的水平由泛素蛋白酶体系统通过E3泛素连接酶parkin的结合和泛素化来调控。 PARIS是在帕金森失活模型和人脑帕金森病患者中积累的KRAB和锌指蛋白。 PARIS通过与PGC-1α启动子中的胰岛素应答序列结合来抑制转录辅助激活物PGC-1α和PGC-1α靶基因NRF-1的表达。成年动物中parkin的条件敲除导致PARIS依赖性的多巴胺（DA）神经元的进行性丧失。 PARIS的过度表达导致黑质中的DA神经元的选择性丧失，其被parkin或PGC-1alpha共表达所逆转。 PARIS的鉴定提供了由于parkin失活引起的神经变性的分子机制。

5. 发明授权

US08135235B2 Pre-processing method and apparatus for wide dynamic range image processing 有权
标题翻译：用于宽动态范围图像处理的预处理方法和装置
公开(公告)号：US08135235B2
公开(公告)日：2012-03-13
申请号：US12381920
申请日：2009-03-18
申请人： Bong-hyup Kang , Chang-won Jeon , Han-seok Ko
发明人： Bong-hyup Kang , Chang-won Jeon , Han-seok Ko
IPC分类号： G06K9/36 , G09G5/02 , H04N9/77
CPC分类号： H04N5/20 , H04N5/2353 , H04N5/2355
摘要： Provided are method and apparatus of pre-processing in WDR (wide dynamic range) image processing, the method of pre-processing of WDR image processing including: (a) receiving luminance and chrominance signals having different exposure times, and analyzing the correlation between a luminance signal having a first exposure time and a luminance signal having a second exposure time that is longer than the first exposure time; (b) based on the result of the analysis, dividing each of the luminance signal having the first exposure time and the luminance signal having the second exposure signal, into at least one of a bright region, a transition region, and a dark region; and (c) normalizing the regions of the luminance signal having the first exposure time to respectively correspond to the regions of the luminance signal having the second exposure times.
摘要翻译：提供了在WDR（宽动态范围）图像处理中预处理的方法和装置，WDR图像处理的预处理方法包括：（a）接收具有不同曝光时间的亮度和色度信号，并分析其中的相关性具有第一曝光时间的亮度信号和具有比第一曝光时间长的第二曝光时间的亮度信号; （b）基于分析结果，将具有第一曝光时间的亮度信号和具有第二曝光信号的亮度信号分成亮区域，过渡区域和暗区域中的至少一个; 以及（c）对具有第一曝光时间的亮度信号的区域进行归一化，以分别对应于具有第二曝光时间的亮度信号的区域。

6. 发明申请

US20120122958A1 TRANSCRIPTIONAL REPRESSION LEADING TO PARKINSON'S DISEASE 有权
标题翻译：导致PARKINSON疾病的转诊
公开(公告)号：US20120122958A1
公开(公告)日：2012-05-17
申请号：US13294909
申请日：2011-11-11
申请人： Ted M. Dawson , Valina L. Dawson , Han Seok Ko , Jooho Shin
发明人： Ted M. Dawson , Valina L. Dawson , Han Seok Ko , Jooho Shin
IPC分类号： A61K31/7088 , C12Q1/68 , A61P25/16 , G01N33/566 , A61K31/7105 , C07H21/04
CPC分类号： G01N33/6896 , A61K31/7088 , C12N15/113 , C12N15/1137 , C12N2310/14 , C12N2310/531 , C12N2320/30 , C12Q1/6883 , C12Q2600/158 , C12Y603/02019 , G01N33/6872 , G01N2333/4704 , G01N2800/2835
摘要： Parkinson's disease is caused by the preferential loss of substantia nigra dopamine neurons. A Parkin Interacting Substrate, PARIS (ZNF746) is identified. The levels of PARIS are regulated by the ubiquitin proteasome system via binding to and ubiquitination by the E3 ubiquitin ligase, parkin. PARIS is a KRAB and zinc finger protein that accumulates in models of parkin inactivation and in human brain Parkinson's disease patients. PARIS represses the expression of the transcriptional co-activator, PGC-1α and the PGC-1α target gene, NRF-1 by binding to insulin response sequences in the PGC-1α promoter. Conditional knockout of parkin in adult animals leads to progressive loss of dopamine (DA) neurons that is PARIS dependent. Overexpression of PARIS causes selective loss of DA neurons in the substantia nigra, which is reversed by either parkin or PGC-1α co-expression. The identification of PARIS provides a molecular mechanism for neurodegeneration due to parkin inactivation.
摘要翻译：帕金森病由黑质多巴胺神经元的优先丧失引起。确定了帕金相互作用基板，巴黎（ZNF746）。 PARIS的水平由泛素蛋白酶体系统通过E3泛素连接酶parkin的结合和泛素化来调控。 PARIS是在帕金森失活模型和人脑帕金森病患者中积累的KRAB和锌指蛋白。 PARIS通过与PGC-1α启动子中的胰岛素应答序列结合来抑制转录辅助激活物PGC-1α和PGC-1α靶基因NRF-1的表达。成年动物中parkin的条件敲除导致PARIS依赖性的多巴胺（DA）神经元的进行性丧失。 PARIS的过度表达导致黑质中的DA神经元的选择性丧失，其被parkin或PGC-1α共表达所逆转。 PARIS的鉴定提供了由于parkin失活引起的神经变性的分子机制。

7. 发明申请

US20090268963A1 Pre-processing method and apparatus for wide dynamic range image processing 有权
标题翻译：用于宽动态范围图像处理的预处理方法和装置
公开(公告)号：US20090268963A1
公开(公告)日：2009-10-29
申请号：US12381920
申请日：2009-03-18
申请人： Bong-hyup Kang , Chang-won Jeon , Han-seok Ko
发明人： Bong-hyup Kang , Chang-won Jeon , Han-seok Ko
IPC分类号： G06K9/00 , H04N9/77
CPC分类号： H04N5/20 , H04N5/2353 , H04N5/2355
摘要： Provided are method and apparatus of pre-processing in WDR (wide dynamic range) image processing, the method of pre-processing of WDR image processing including: (a) receiving luminance and chrominance signals having different exposure times, and analyzing the correlation between a luminance signal having a first exposure time and a luminance signal having a second exposure time that is longer than the first exposure time; (b) based on the result of the analysis, dividing each of the luminance signal having the first exposure time and the luminance signal having the second exposure signal, into at least one of a bright region, a transition region, and a dark region; and (c) normalizing the regions of the luminance signal having the first exposure time to respectively correspond to the regions of the luminance signal having the second exposure times.
摘要翻译：提供了在WDR（宽动态范围）图像处理中预处理的方法和装置，WDR图像处理的预处理方法包括：（a）接收具有不同曝光时间的亮度和色度信号，并分析其中的相关性具有第一曝光时间的亮度信号和具有比第一曝光时间长的第二曝光时间的亮度信号; （b）基于分析结果，将具有第一曝光时间的亮度信号和具有第二曝光信号的亮度信号分成亮区域，过渡区域和暗区域中的至少一个; 以及（c）对具有第一曝光时间的亮度信号的区域进行归一化，以分别对应于具有第二曝光时间的亮度信号的区域。

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