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1. 发明申请

US20180160971A1 STEREORADIOGRAPHY MEASUREMENT OF ARTHROPLASTY IMPLANT LOOSENING 审中-公开
公开(公告)号：US20180160971A1
公开(公告)日：2018-06-14
申请号：US15580727
申请日：2016-06-10
申请人： HALIFAX BIOMEDICAL INC.
发明人： Johan Erik Giphart , Chad Munro
IPC分类号： A61B5/00 , A61B6/02 , A61B6/00 , A61F2/46
CPC分类号： A61B5/4851 , A61B5/6878 , A61B6/022 , A61B6/0421 , A61B6/0492 , A61B6/12 , A61B6/505 , A61B2090/3966 , A61F2/30 , A61F2/468 , A61F2002/3008
摘要： The present invention relates to a device and use of the device for detection and loosening of implants installed into a subject's host bone, the device comprising: a frame for encircling and demountably engaging a portion of the subject's appendage comprising the host bone with installed implant; and at least three-spaced apart attachments engaged with the frame, wherein each attachment is configured to house and to retractably deploy a sharp geometry component for contacting the host bone, wherein a temporary reference frame is created when the three-spaced apart attachments contact the host bone. The use of the device comprises obtaining a first pair of stereo radiographs of the implant under a first loading condition and obtaining a second pair of stereo radiographs of the implant and host bone area under the second loading condition and comparing the two radiographs to detect displacement of the implant.

2. 发明申请

WO2016197249A1 STEREORADIOGRAPHY MEASUREMENT OF ARTHROPLASTY IMPLANT LOOSENING 审中-公开
标题翻译：牙周植入物松弛的立体定向测量
公开(公告)号：WO2016197249A1
公开(公告)日：2016-12-15
申请号：PCT/CA2016/050661
申请日：2016-06-10
申请人： HALIFAX BIOMEDICAL INC.
发明人： GIPHART, Johan Erik , MUNRO, Chad
IPC分类号： A61B6/02 , A61B5/103 , A61F2/30
CPC分类号： A61B5/4851 , A61B5/6878 , A61B6/022 , A61B6/0421 , A61B6/0492 , A61B6/12 , A61B6/505 , A61B2090/3966 , A61F2/30 , A61F2/468 , A61F2002/3008
摘要： The present invention relates to a device and use of the device for detection and loosening of implants installed into a subject's host bone, the device comprising: a frame for encircling and demountably engaging a portion of the subject's appendage comprising the host bone with installed implant; and at least three-spaced apart attachments engaged with the frame, wherein each attachment is configured to house and to retractably deploy a sharp geometry component for contacting the host bone, wherein a temporary reference frame is created when the three-spaced apart attachments contact the host bone. The use of the device comprises obtaining a first pair of stereo radiographs of the implant under a first loading condition and obtaining a second pair of stereo radiographs of the implant and host bone area under the second loading condition and comparing the two radiographs to detect displacement of the implant.
摘要翻译：本发明涉及一种用于检测和松动安装在受试者宿主骨中的植入物的装置和装置的装置，该装置包括：框架，用于环绕并可拆卸地与主体骨骼的一部分包括主体骨骼的植入物接合; 以及与所述框架接合的至少三个间隔开的附件，其中每个附件被配置成容纳和缩回地展开用于接触所述主体骨的尖锐几何部件，其中当所述三个间隔开的附件接触所述主体骨时，产生临时参考框架宿主骨。使用该装置包括在第一加载条件下获得植入物的第一对立体射线照片，并在第二加载条件下获得植入物和宿主骨区域的第二对立体射线照片，并比较两张X射线以检测植入物。

3. 发明申请

US20180342315A1 METHOD FOR 3D IMAGING OF MECHANICAL ASSEMBLIES TRANSPLANTED INTO MAMMALIAN SUBJECTS 审中-公开
公开(公告)号：US20180342315A1
公开(公告)日：2018-11-29
申请号：US15755936
申请日：2016-08-31
申请人： HALIFAX BIOMEDICAL INC.
发明人： Johan Erik Giphart , Yann Gagnon
IPC分类号： G16H30/40 , G06T7/50
摘要： A medical imaging method is described for establishing implant configuration by measuring the positions and orientations of its components constrained by a defined kinematic relationship between them using stereo radiography images. The method allows the determination of a patient-specific implant configuration and enables accurate measurements of the pose of implant despite significant occlusions. The measurements obtained with this method can be used to determine the relative movement of an implant component relative to other components, bone or other landmark.

4. 发明授权

US10135220B2 Synchronized tunable mode-locked lasers 有权
公开(公告)号：US10135220B2
公开(公告)日：2018-11-20
申请号：US15667440
申请日：2017-08-02
申请人： Halifax Biomedical Inc.
发明人： Bryan Burgoyne
IPC分类号： H01S3/11 , H01S3/23 , H01S3/109 , H01S3/08 , H01S3/106 , H01S3/067 , H01S3/10
摘要： A synchronized laser system for illuminating a sample with first and second laser light pulses, said system comprising: a trigger, said trigger being operative to issue first and second trigger signals, said first and second trigger signals being emitted at an adjustable frequency with a predetermined delay therebetween; a first tunable mode-locked laser operative for emitting said first laser light pulses in response to receiving a train of said first trigger signals, a first wavelength of said first laser light pulses being dependent on said adjustable frequency in accordance with a first wavelength-frequency relationship; a second tunable mode-locked laser operative for emitting said second laser light pulses in response to receiving a train of said second trigger signals, a second wavelength of said second laser light pulses being dependent on said adjustable frequency in accordance with a second wavelength-frequency relationship; wherein said predetermined delay is such that said first and second laser light pulses are emitted so as to arrive substantially simultaneously in said sample; and said first and second wavelength-frequency relationships are selected to result in a predetermined relationship between said first and second wavelengths at each frequency.

5. 发明申请

WO2017035648A1 METHOD FOR 3D IMAGING OF MECHANICAL ASSEMBLIES TRANSPLANTED INTO MAMMALIAN SUBJECTS 审中-公开
标题翻译：机械装置三维成像方法转移到马马里亚物种
公开(公告)号：WO2017035648A1
公开(公告)日：2017-03-09
申请号：PCT/CA2016/051025
申请日：2016-08-31
申请人： HALIFAX BIOMEDICAL INC.
发明人： GIPHART, Johan Erik , GAGNON, Yann
IPC分类号： A61B6/02 , A61B6/12 , A61B90/00
CPC分类号： A61B6/032 , A61B6/12 , A61B6/541 , A61B8/085 , A61B8/5223 , A61B8/5246 , A61B8/5261 , A61B90/00 , A61B2034/102 , A61B2090/367 , A61B2090/3966
摘要： A medical imaging method is described for establishing implant configuration by measuring the positions and orientations of its components constrained by a defined kinematic relationship between them using stereo radiography images. The method allows the determination of a patient-specific implant configuration and enables accurate measurements of the pose of implant despite significant occlusions. The measurements obtained with this method can be used to determine the relative movement of an implant component relative to other components, bone or other landmark.
摘要翻译：描述了一种医学成像方法，用于通过使用立体放射摄影图像测量由它们之间的确定的运动学关系约束的其部件的位置和取向来建立植入物构型。该方法允许确定特定于患者的植入物构型，并且能够精确地测量植入物的姿态，尽管有显着的闭塞。用这种方法获得的测量结果可用于确定植入部件相对于其他部件，骨骼或其他标记物的相对运动。

6. 发明申请

WO2012024783A1 A METHOD OF DETECTING MOVEMENT BETWEEN AN IMPLANT AND A BONE 审中-公开
标题翻译：检测植入物和骨骼之间的运动的方法
公开(公告)号：WO2012024783A1
公开(公告)日：2012-03-01
申请号：PCT/CA2011/000967
申请日：2011-08-25
申请人： HALIFAX BIOMEDICAL INC. , MUNRO, Chad, R. , VAN DER PUT, Richard, W. , BURGER, Andreas
发明人： MUNRO, Chad, R. , VAN DER PUT, Richard, W. , BURGER, Andreas
IPC分类号： A61B17/56 , A61B17/68 , A61B17/88 , A61B6/12 , A61F2/28
CPC分类号： A61B6/022 , A61B6/12 , A61B6/486 , A61B6/505 , A61B6/5229 , A61B17/7032 , A61B17/864 , A61B90/39 , A61B2090/061 , A61B2090/0812 , A61B2090/3904 , A61B2090/3916 , A61B2090/3966 , A61B2090/3987 , A61F2002/4658
摘要： A method of measuring the relative position of a bone implant within a bone in a patient to detect movement between the implant and bone is provided, wherein one or more radiopaque bone markers have been implanted into the bone through a cannulated implant within the bone and one or more radiopaque implant markers have been implanted into the implant. The method comprises: i) determining a first relative position of the bone marker to the implant marker under a first parameter; and ii) determining a second relative position of the bone marker to the implant marker under a second parameter, wherein a change in the position of the bone marker relative to the implant marker from the first relative position to the second relative position is indicative of movement of either the implant or the bone.
摘要翻译：提供了一种测量患者中骨骼内骨骼相对位置以检测植入物和骨骼之间的运动的方法，其中一个或多个不透射线的骨标记物已经通过骨内的插管植入物植入到骨骼中，一个或更多的不透射线的植入物标记已被植入到植入物中。该方法包括：i）在第一参数下确定骨标记物与植入物标记物的第一相对位置; 以及ii）在第二参数下确定所述骨标记物与所述植入物标记物的第二相对位置，其中所述骨标记物相对于所述植入物标记物从所述第一相对位置到所述第二相对位置的位置的变化指示运动植入物或骨骼。

7. 发明申请

US20180048112A1 SYNCHRONIZED TUNABLE MODE-LOCKED LASERS 审中-公开
公开(公告)号：US20180048112A1
公开(公告)日：2018-02-15
申请号：US15667440
申请日：2017-08-02
申请人： Halifax Biomedical Inc.
发明人： Bryan Burgoyne
IPC分类号： H01S3/11 , H01S3/23 , H01S3/106 , H01S3/08 , H01S3/067 , H01S3/109 , H01S3/10
CPC分类号： H01S3/1109 , H01S3/0675 , H01S3/06791 , H01S3/08054 , H01S3/08086 , H01S3/10053 , H01S3/1061 , H01S3/109 , H01S3/2383 , H01S3/2391
摘要： A synchronized laser system for illuminating a sample with first and second laser light pulses, said system comprising: a trigger, said trigger being operative to issue first and second trigger signals, said first and second trigger signals being emitted at an adjustable frequency with a predetermined delay therebetween; a first tunable mode-locked laser operative for emitting said first laser light pulses in response to receiving a train of said first trigger signals, a first wavelength of said first laser light pulses being dependent on said adjustable frequency in accordance with a first wavelength-frequency relationship; a second tunable mode-locked laser operative for emitting said second laser light pulses in response to receiving a train of said second trigger signals, a second wavelength of said second laser light pulses being dependent on said adjustable frequency in accordance with a second wavelength-frequency relationship; wherein said predetermined delay is such that said first and second laser light pulses are emitted so as to arrive substantially simultaneously in said sample; and said first and second wavelength-frequency relationships are selected to result in a predetermined relationship between said first and second wavelengths at each frequency.

8. 发明申请

US20170273614A1 SYSTEMS AND METHODS FOR MEASURING AND ASSESSING SPINE INSTABILITY 审中-公开
公开(公告)号：US20170273614A1
公开(公告)日：2017-09-28
申请号：US15505014
申请日：2015-08-21
申请人： Halifax Biomedical Inc.
发明人： Johan Erik GIPHART , Yann GAGNON , Chad MUNRO , Richard VAN DE PUT
IPC分类号： A61B5/00 , A61B6/03 , A61B6/04 , A61B5/107 , G06T7/00 , A61B34/10 , A61B6/02 , G01R33/56 , G06T7/73 , A61B6/00 , A61B5/11
CPC分类号： A61B5/4566 , A61B5/1071 , A61B5/1072 , A61B5/1075 , A61B5/1116 , A61B5/1128 , A61B5/4504 , A61B5/4528 , A61B5/702 , A61B6/00 , A61B6/022 , A61B6/032 , A61B6/04 , A61B6/4014 , A61B6/461 , A61B6/466 , A61B6/486 , A61B6/505 , A61B6/5205 , A61B6/5217 , A61B34/10 , A61B2034/105 , A61B2034/107 , A61B2090/376 , G01R33/5608 , G06T7/0014 , G06T7/75 , G06T17/00 , G06T2207/10016 , G06T2207/10088 , G06T2207/10116 , G06T2207/30008 , G06T2207/30012 , G06T2211/412 , H04N13/00
摘要： Diagnostic systems and methods for measuring and assessing spine instability are described which involve reconstruction of a dynamic three-dimensional model of a patient's spine moving through a range of motions, and optimization of the three-dimensional model to provide relative three-dimensional position and orientation data for each vertebra in the spine throughout the motion. Vertebral movement is thereby accurately measured and instability determined for presentation in a user-friendly form.

9. 发明申请

WO2016026053A1 SYSTEMS AND METHODS FOR MEASURING AND ASSESSING SPINAL INSTABILITY 审中-公开
标题翻译：用于测量和评估脊柱不稳定性的系统和方法
公开(公告)号：WO2016026053A1
公开(公告)日：2016-02-25
申请号：PCT/CA2015/050805
申请日：2015-08-21
申请人： HALIFAX BIOMEDICAL INC.
发明人： GIPHART, Johan Erik , GAGNON, Yann , MUNRO, Chad , VAN DE PUT, Richard
IPC分类号： A61B6/02 , A61B5/103 , A61B6/03 , A61B6/04
CPC分类号： A61B5/4566 , A61B5/1071 , A61B5/1072 , A61B5/1075 , A61B5/1116 , A61B5/1128 , A61B5/4504 , A61B5/4528 , A61B5/702 , A61B6/00 , A61B6/022 , A61B6/032 , A61B6/04 , A61B6/4014 , A61B6/461 , A61B6/466 , A61B6/486 , A61B6/505 , A61B6/5205 , A61B6/5217 , A61B34/10 , A61B2034/105 , A61B2034/107 , A61B2090/376 , G01R33/5608 , G06T7/0014 , G06T7/75 , G06T17/00 , G06T2207/10016 , G06T2207/10088 , G06T2207/10116 , G06T2207/30008 , G06T2207/30012 , G06T2211/412 , H04N13/00
摘要： Diagnostic systems and methods for measuring and assessing spine instability are described which involve reconstruction of a dynamic three-dimensional model of a patient's spine moving through a range of motions, and optimization of the three- dimensional model to provide relative three-dimensional position and orientation data for each vertebra in the spine throughout the motion. Vertebral movement is thereby accurately measured and instability determined for presentation in a user-friendly form.
摘要翻译：描述了用于测量和评估脊柱不稳定性的诊断系统和方法，其涉及重建通过一系列运动的患者脊柱的动态三维模型，并且优化三维模型以提供相对的三维位置和取向在整个运动期间脊柱中每个椎骨的数据。因此，精确测量椎体运动并确定用于以用户友好形式呈现的不稳定性。

10. 发明申请

WO2010096927A8 DEVICE AND METHOD FOR BONE IMAGING 审中-公开
标题翻译：用于骨成像的装置和方法
公开(公告)号：WO2010096927A8
公开(公告)日：2011-09-09
申请号：PCT/CA2010000273
申请日：2010-02-26
申请人： HALIFAX BIOMEDICAL INC , MUNRO CHAD
发明人： MUNRO CHAD
IPC分类号： A61L27/50 , A61F2/02 , A61F2/28 , A61L27/04 , A61L27/06
CPC分类号： A61L31/18 , A61B6/12 , A61B90/39 , A61B2090/3916 , A61F2250/0032 , A61F2250/0098 , A61L2430/02
摘要： The invention comprises a modified implant useful to assess bone by imaging. The modified implant comprises a medical implant and at least one detectable marker element associated with the implant that serves as a reference point in medical imaging. Preferably, the implant and the detector marker elements have different radiolucencies such that one element can be seen through the other in medical imaging.
摘要翻译：本发明包括用于通过成像来评估骨骼的修改的植入物。修改的植入物包括医疗植入物和与植入物相关联的至少一个可检测的标记元件，其用作医学成像中的参考点。优选地，植入物和检测器标记元件具有不同的放射性，使得在医学成像中可以通过另一个元件看到一个元件。

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