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1. 发明授权

US4790318A Cardiac pacer for pacing a human heart 失效
标题翻译：心脏起搏器用于起搏人心脏
公开(公告)号：US4790318A
公开(公告)日：1988-12-13
申请号：US874597
申请日：1986-06-16
申请人： Hakan Elmqvist , Anders Lekholm , Sven-Erik Hedberg , David C. Amundson
发明人： Hakan Elmqvist , Anders Lekholm , Sven-Erik Hedberg , David C. Amundson
IPC分类号： A61N1/365 , A61N1/36
CPC分类号： A61N1/36521
摘要： A cardiac pacer which generates pacing pulses at a predetermined pacing rate, includes a device for generating an alternating signal which is unable to pace the heart. The pacing pulses and the alternating signal are transmitted together to the heart. The alternating signal after transmittal to the heart is measured and processed such that a respiratory signal is obtained. The predetermined pacing rate is then varied dependent on the respiratory signal.

2. 发明授权

US4788528A Method and apparatus for high-resolution digitization of a signal 失效
标题翻译：用于信号高分辨率数字化的方法和装置
公开(公告)号：US4788528A
公开(公告)日：1988-11-29
申请号：US51162
申请日：1987-05-15
申请人： Hakan Elmqvist
发明人： Hakan Elmqvist
IPC分类号： H03M1/18 , H03M1/00 , H03M1/46
CPC分类号： H03M1/10
摘要： A method and apparatus for high-resolution digitization of a signal with a large dynamic range employ an analog-to-digital converter having a bit number and having a measuring region which is smaller than the total range of measurement of the incoming signal, the range of measurement being divided into smaller measuring segments which partically overlap, each measuring segment having a size corresponding to the measuring ranges of the analog-to-digital converter. The information from the analog-to-digital converter controls a measurement segment selector such that the signal to be converted into digital form is within the selected segment. A new digital signal value is extrapolated at least from the two last bits from the analog-to-digital converter.
摘要翻译：用于具有大动态范围的信号的高分辨率数字化的方法和装置采用具有比特数并具有小于输入信号的总测量范围的测量区域的模拟 - 数字转换器，范围的测量分为较小的测量段，其部分重叠，每个测量段的尺寸对应于模数转换器的测量范围。来自模数转换器的信息控制测量段选择器，使得要转换成数字形式的信号在所选择的段内。至少从模数转换器的最后两位，外插一个新的数字信号值。

3. 发明授权

US4781194A Heart pacemaker 失效
标题翻译：心脏起搏器
公开(公告)号：US4781194A
公开(公告)日：1988-11-01
申请号：US466629
申请日：1983-02-15
申请人： Hakan Elmqvist
发明人： Hakan Elmqvist
IPC分类号： A61N1/368 , A61N1/362 , A61N1/32
CPC分类号： A61N1/3622
摘要： A heart pacemaker has a controllable time delay element for setting the time between atrial and ventricular activity (AV time). For terminating tachycardia as quickly as possible with such a heart pacemaker, a detector for detecting tachycardia is provided with the time delay element being driven by means of the detector such that the AV time is altered upon the occurrence of tachycardia. The change in the AV time is selected such that the new AV time is an optimum for terminating tachycardia. After a preselected time, the time delay element returns to the original AV time.
摘要翻译：心脏起搏器具有可控的时间延迟元件，用于设置心房和心室活动之间的时间（AV时间）。为了用这种心脏起搏器尽可能快地终止心动过速，提供了用于检测心动过速的检测器，其中延迟元件通过检测器驱动，使得AV发生在心动过速时被改变。选择AV时间的变化使得新的AV时间对于终止心动过速是最佳的。在预选的时间之后，延时元件返回原来的AV时间。

4. 发明授权

US4388928A Signal processing means particularly for heart pacemakers 失效
标题翻译：信号处理特别适用于心脏起搏器
公开(公告)号：US4388928A
公开(公告)日：1983-06-21
申请号：US190221
申请日：1980-09-24
申请人： Christer Ekwall , Hakan Elmqvist
发明人： Christer Ekwall , Hakan Elmqvist
IPC分类号： A61N1/36 , A61N1/372 , G06F12/14
CPC分类号： A61N1/37211 , A61N1/37252 , G06F12/1466
摘要： The exemplary embodiment comprising a signal reception part and a routing device which routes specific signal information for storage to information memories provided for that purpose. The goal of the disclosure is to create such a signal processing means which, given the lowest possible circuit-technical outlay, always prevents an undesired re-programming of information memories with absolute certainty. This goal is inventively achieved in that a locking register is allocated to a memory bank constructed of a plurality of information memories, in which locking register a locking signal can be inscribed for each information memory which is specifically allocated to this information memory, on the basis of which locking signal a change of the stored informational content is made impossible as long as no opening signal for an appertaining information memory is input into the locking register from the outside.
摘要翻译：示例性实施例包括信号接收部分和路由设备，路由设备将特定信号信息路由存储到为此目的而提供的信息存储器中。本公开的目的是创建这样一种信号处理装置，其给出尽可能低的电路技术支出，总是以绝对确定的方式防止对信息存储器的不期望的重新编程。本发明的目的是将锁定寄存器分配给由多个信息存储器构成的存储器组，其中锁存寄存器可以基于专门分配给该信息存储器的每个信息存储器内嵌锁定信号只要没有从外部向锁定寄存器输入有关信息存储器的打开信号，则锁定信号使存储的信息内容的改变变得不可能。

5. 发明授权

US4830488A Measuring instrument for intracardial acquisition of blood oxygen saturation 失效
标题翻译：测量仪器用于血氧饱和度的心内采集
公开(公告)号：US4830488A
公开(公告)日：1989-05-16
申请号：US51857
申请日：1987-05-20
申请人： Roland Heinze , Hakan Elmqvist
发明人： Roland Heinze , Hakan Elmqvist
IPC分类号： A61B5/145 , A61B5/1459 , A61N1/365
CPC分类号： A61N1/36557
摘要： A measuring instrument for obtaining an intracardial signal indicative of blood oxygen saturation, which may be used to control the stimulation frequency of a heart pacemaker, has a measuring probe which contains a light transmitter and a light receiver. The light receiver receives light from the light transmitter reflected by the blood. The light transmitter and the light receiver are connected in parallel to an evaluation circuit via two leads. A constant current source is connected in series with the light transmitter. The current generated by the light receiver, indicative of blood oxygen saturation, can be identified by forming the difference between current flowing in the measuring probe and the constant current. A reference measurement to compensate for factors in the total current resulting from the lead resistances and the measuring probe temperature is not necessary.
摘要翻译：可用于控制心脏起搏器的刺激频率的用于获得指示血氧饱和度的心内信号的测量仪器具有包含光发射器和光接收器的测量探针。光接收器接收来自由血液反射的光发射器的光。光发射器和光接收器通过两根引线并联连接到评估电路。恒流源与光发射器串联连接。由光接收器产生的指示血氧饱和度的电流可以通过形成测量探头中流动的电流与恒定电流之间的差异来识别。用于补偿由导通电阻和测量探头温度导致的总电流中的因素的参考测量不是必需的。

6. 发明授权

US4321928A Heart pacemaker 失效
标题翻译：心脏起搏器
公开(公告)号：US4321928A
公开(公告)日：1982-03-30
申请号：US188518
申请日：1980-09-18
申请人： Hakan Elmqvist
发明人： Hakan Elmqvist
IPC分类号： A61N1/362 , A61N1/372 , A61N1/36
CPC分类号： A61N1/37223 , A61N1/362
摘要： In the exemplary embodiments, the processing circuit for supplying the stimulation pulses comprises a series arrangement of capacitors which are chargeable in parallel and dischargeable serially. The goal of the disclosure, given such a heart pacemaker, is to see to the greatest possible variability of the output amplitude given the lowest possible technical outlay. This goal is inventively achieved in that program switches are allocated to the capacitor circuit for interconnecting or, respectively, disconnecting individual capacitors in combination randomly prescribable as needed for parallel charging and/or serial discharge, said interconnection or, respectively, disconnection occurring according to programs of a program generator.
摘要翻译：在示例性实施例中，用于提供刺激脉冲的处理电路包括可并联并可串行放电的电容器的串联布置。给予这种心脏起搏器的披露的目标是鉴于最低可能的技术支出，可以看出输出幅度的最大可能变化。这个目标是在程序开关被分配给电容器电路的情况下被分配到电容器电路中，用于互连或者分别断开并联充电和/或串联放电所需的随机规定的各个电容器，所述互连或分别根据程序发生断开的程序生成器。

7. 发明授权

US4602637A Heart pacemaker system 失效
标题翻译：心脏起搏器系统
公开(公告)号：US4602637A
公开(公告)日：1986-07-29
申请号：US569979
申请日：1984-01-11
申请人： Hakan Elmqvist , Konrad Mund
发明人： Hakan Elmqvist , Konrad Mund
IPC分类号： A61N1/05 , A61N1/375 , A61N1/04
CPC分类号： A61N1/375 , A61N1/056
摘要： Provided in order to avoid or at least reduce the problems produced by the passive electrode of a heart pacemaker system is a layer having a high double layer capacitance at the phase boundary with the bodily fluid. Advantageous to that end is a porous layer comprised of a carbide, nitride or carbonitride of at least one of the metals titanium, vanadium, zirconium, niobium, molybdenum, hafnium, tantalum or tungsten. The layer can also be comprised of activated carbon with a microporous exposed surface. The layer is produced in the simplest manner by means of roughening the existing electrode surface at its active area.
摘要翻译：提供为了避免或至少减少心脏起搏器系统的被动电极产生的问题是在与体液的相位边界处具有高双层电容的层。有利的是由金属钛，钒，锆，铌，钼，铪，钽或钨中的至少一种的碳化物，氮化物或碳氮化物组成的多孔层。该层还可以由具有微孔暴露表面的活性炭组成。通过在其有效区域粗糙化现有的电极表面，以最简单的方式制造该层。

8. 发明授权

US4541430A Method and a heart pacemaker for terminating a tachycardia 失效
标题翻译：方法和用于终止心动过速的心脏起搏器
公开(公告)号：US4541430A
公开(公告)日：1985-09-17
申请号：US546457
申请日：1983-10-28
申请人： Hakan Elmqvist , Hans Strandberg
发明人： Hakan Elmqvist , Hans Strandberg
IPC分类号： A61N1/365 , A61N1/362 , A61N1/372 , A61N1/39 , A61N1/36
CPC分类号： A61N1/3621
摘要： A routine is provided in order to be able to terminate a detected tachycardia quickly and reliably, the routine generating a sequence of n stimulation pulses, checking the heart reaction and, under given conditions, changing the sequence until the sequence terminates the tachycardia. The effective sequences are stored in a plurality of registers and are employed in a prescribable order for controlling the stimulation pulses. In addition to the traditional electronics, a heart pacemaker for the implementation of this method contains a tachycardia detector, a memory having N registers for the sequences to be stored, as well as a control logic for the selection of the registers and/or for changing the register values.
摘要翻译：提供了一种例程，以便能够快速可靠地终止检测到的心动过速，例程产生n个刺激脉冲序列，检查心脏反应，并且在给定条件下，改变序列直到序列终止心动过速。有效序列存储在多个寄存器中，并以可规定的顺序被用于控制刺激脉冲。除了传统的电子设备之外，用于实施该方法的心脏起搏器还包括心动过速检测器，具有用于存储的序列的N个寄存器的存储器，以及用于选择寄存器和/或用于改变的控制逻辑寄存器值。

9. 发明申请

US20090143651A1 Device for Invasive Use 审中-公开
标题翻译：有创用途装置
公开(公告)号：US20090143651A1
公开(公告)日：2009-06-04
申请号：US12301536
申请日：2007-05-31
申请人： Bengt Kallback , Anders Hult , Lars-Ake Brodin , Hakan Elmqvist
发明人： Bengt Kallback , Anders Hult , Lars-Ake Brodin , Hakan Elmqvist
IPC分类号： A61B5/04 , A61B1/05 , A61M25/00 , B29C47/00 , A61B1/04 , A61N1/05
CPC分类号： A61N1/05 , A61B5/02007 , A61B5/0215 , A61B5/026 , A61B5/0422 , A61B5/053 , A61B5/0538 , A61B5/14539 , A61B5/1473 , A61B5/6855 , A61B2562/125 , A61N1/056 , A61N2001/0585 , B29C53/52 , B29C53/84 , B29L2031/7542 , H05K1/0272 , H05K1/0274 , H05K1/0289 , H05K1/118 , H05K1/189 , H05K2201/051 , H05K2201/09072 , H05K2203/0126
摘要： A device for invasive use, comprising a support member comprising a flexible material. The support member comprises a layer of a conductive line or pattern thereon. The support member is formed into an elongated tube shape, and the inside of the support member can be sealed from the outside of the support member. An electrically conductive line or pattern extends on the inside of the tube shaped support member, and the support member may comprise a sensing, stimulating and/or processing element. Furthermore, there is described a manufacturing method for the device, a system where the device is a part of the system and the use of the device for invasive use.
摘要翻译：一种用于侵入性用途的装置，包括包括柔性材料的支撑构件。支撑构件包括其上的导电线或图案层。支撑构件形成为细长的管状，并且支撑构件的内部可以从支撑构件的外部密封。导电线或图案在管状支撑构件的内侧延伸，并且支撑构件可包括感测，刺激和/或处理元件。此外，描述了该装置的制造方法，该装置是系统的一部分的系统以及该装置用于侵入性使用的系统。

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