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1. 发明公开

EP0935428A1 KNEE PAD 失效
标题翻译：护膝
公开(公告)号：EP0935428A1
公开(公告)日：1999-08-18
申请号：EP97943353.0
申请日：1997-09-18
申请人： Kroll, Michael I. , Holden, Kevin D.
发明人： HOLDEN, Kevin, D.
IPC分类号： A41D13
CPC分类号： A41D13/0562 , A41D13/0556 , A41D13/065 , Y10S2/911
摘要： A knee pad (16) for cushioning a knee of a person (18) wearing a pair of pants (20), when the person (18) is in a kneeling position. The knee pad (16) comprises a cushion member (22) being a flexible semi-cylindrical body section (24) having a flat outer surface contact area (26) with tapered sides (28) and an integral flexible quadrispherical cut back top section (30). A facility (32) is for attaching the cushion member (22) in a removable manner to a pants leg (34) of the pair of pants (20) at a knee area. When the person (18) goes into the kneeling position on a floor/ground (36), the cushion member (22) will better conform to the knee of the person (18). The flat outer surface contact area (26) will distribute weight more evenly over a wider surface area on the floor/ground (36).

2. 发明公开

EP0935428A4 KNEE PAD 失效
标题翻译： KNIESCHÜTZER
公开(公告)号：EP0935428A4
公开(公告)日：1999-11-03
申请号：EP97943353
申请日：1997-09-18
申请人： KROLL MICHAEL I , HOLDEN KEVIN D
发明人： HOLDEN KEVIN D
IPC分类号： A41D13/06 , A41D27/12
CPC分类号： A41D13/0562 , A41D13/0556 , A41D13/065 , Y10S2/911
摘要： A knee pad (16) for cushioning a knee of a person (18) wearing a pair of pants (20), when the person (18) is in a kneeling position. The knee pad (16) comprises a cushion member (22) being a flexible semi-cylindrical body section (24) having a flat outer surface contact area (26) with tapered sides (28) and an integral flexible quadrispherical cut back top section (30). A facility (32) is for attaching the cushion member (22) in a removable manner to a pants leg (34) of the pair of pants (20) at a knee area. When the person (18) goes into the kneeling position on a floor/ground (36), the cushion member (22) will better conform to the knee of the person (18). The flat outer surface contact area (26) will distribute weight more evenly over a wider surface area on the floor/ground (36).
摘要翻译：当人（18）处于跪姿时，护膝（16）用于缓冲穿着一条裤子（20）的人（18）的膝盖。护膝（16）包括作为柔性半圆柱体部分（24）的衬垫部件（22），柔性半圆柱体部分（24）具有带有锥形侧面（28）的平坦外表面接触区域（26）和整体柔性四边形切口顶部部分 30）。设备（32）用于以可移除的方式将衬垫构件（22）附接到膝部区域处的一条裤子（20）的裤腿（34）。当人（18）进入地板/地面（36）的跪姿时，缓冲构件（22）将更好地贴合人（18）的膝盖。平坦的外表面接触区域（26）将更均匀地分布在地板/地面（36）上的更宽的表面区域上。

3. 发明公开

EP2834352A2 IMPROVED PRODUCTION OF FATTY ACID DERIVATIVES 有权转让
标题翻译：改进脂肪酸衍生物的生产
公开(公告)号：EP2834352A2
公开(公告)日：2015-02-11
申请号：EP13715879.6
申请日：2013-04-02
申请人： REG Life Sciences, LLC , Greenfield, Derek L. , Schirmer, Andreas W. , Clarke, Elizabeth J. , Groban, Eli S. , Da Costa, Bernardo M , Hu, Zhihao , Holden, Kevin , Helman, Noah
发明人： GREENFIELD, Derek, L. , SCHIRMER, Andreas, W. , CLARKE, Elizabeth, J. , GROBAN, Eli, S. , DA COSTA, Bernardo, M. , HU, Zhihao , HELMAN, Noah , HOLDEN, Kevin
IPC分类号： C12N9/04 , C12N9/02 , C12N9/10 , C12N9/12 , C12N9/88 , C12N9/90 , C12N9/00 , C12P7/64
摘要： The invention relates to compositions and methods, including polynucleotide sequences, amino acid sequences, recombinant host cells and recombinant host cell cultures engineered to produce fatty acid derivative compositions comprising fatty acids, fatty alcohols, fatty aldehydes, fatty esters, alkanes, terminal olefins, internal olefins or ketones. The fatty acid derivative composition is produced extracellularly with a higher titer, yield or productivity than the corresponding wild type or non-engineered host cell.
摘要翻译：本公开涉及重组宿主细胞，其包括有效改善脂肪酸衍生物的滴度，产量和/或生产力的菌株修饰。本公开还涉及包含用于发酵生产脂肪酸衍生物及其组合物的重组宿主细胞的细胞培养物。

4. 发明专利

CA2362043A1 KNEE PAD 未知
公开(公告)号：CA2362043A1
公开(公告)日：1998-04-02
申请号：CA2362043
申请日：1997-09-18
申请人： HOLDEN KEVIN D
发明人： HOLDEN KEVIN D
IPC分类号： A41D13/06 , A41D27/12
摘要： A knee pad (16) for cushioning a knee of a person (18) wearing a pair of pan ts (20), when the person (18) is in a kneeling position. The knee pad (16) comprises a cushion member (22) being a flexible semi-cylindrical body secti on (24) having a flat outer surface contact area (26) with tapered sides (28) a nd an integral flexible quadrispherical cut back top section (30). A facility (32) is for attaching the cushion member (22) in a removable manner to a pan ts leg (34) of the pair of pants (20) at a knee area. When the person (18) goes into the kneeling position on a floor/ground (36), the cushion member (22) will better conform to the knee of the person (18). The flat outer surface contact area (26) will distribute weight more evenly over a wider surface ar ea on the floor/ground (36).

5. 发明专利

AU2013243601A1 Improved production of fatty acid derivatives 未知
公开(公告)号：AU2013243601A1
公开(公告)日：2014-10-30
申请号：AU2013243601
申请日：2013-04-02
申请人： DA COSTA BERNARDO , SCHIRMER ANDREAS , GROBAN ELI , GREENFIELD DEREK , HELMAN NOAH , HU ZHIHAO , HOLDEN KEVIN , REG LIFE SCIENCES LLC , CLARKE ELIZABETH
发明人： GREENFIELD DEREK L , SCHIRMER ANDREAS W , CLARKE ELIZABETH J , GROBAN ELI S , DA COSTA BERNARDO M , HU ZHIHAO , HOLDEN KEVIN , HELMAN NOAH
IPC分类号： C12N9/00 , C12N9/02 , C12N9/04 , C12N9/10 , C12N9/12 , C12N9/88 , C12N9/90 , C12P7/64
摘要： The disclosure relates to recombinant host cells including strain modifications effective to improve titer, yield and/or productivity of fatty acid derivatives. The disclosure further relates to cell cultures including the recombinant host cells for the fermentative production of fatty acid derivatives and compositions thereof.

6. 发明专利

AU4484497A Knee pad 未知
公开(公告)号：AU4484497A
公开(公告)日：1998-04-17
申请号：AU4484497
申请日：1997-09-18
申请人： HOLDEN KEVIN D , KROLL MICHAEL I
发明人： HOLDEN KEVIN D
IPC分类号： A41D13/06 , A41D27/12
摘要： A knee pad (16) for cushioning a knee of a person (18) wearing a pair of pants (20), when the person (18) is in a kneeling position. The knee pad (16) comprises a cushion member (22) being a flexible semi-cylindrical body section (24) having a flat outer surface contact area (26) with tapered sides (28) and an integral flexible quadrispherical cut back top section (30). A facility (32) is for attaching the cushion member (22) in a removable manner to a pants leg (34) of the pair of pants (20) at a knee area. When the person (18) goes into the kneeling position on a floor/ground (36), the cushion member (22) will better conform to the knee of the person (18). The flat outer surface contact area (26) will distribute weight more evenly over a wider surface area on the floor/ground (36).

7. 发明申请

WO2014042693A1 ENZYME VARIANTS WITH IMPROVED ESTER SYNTHASE PROPERTIES 审中-公开
标题翻译：具有改进的酯合成特性的酶变体
公开(公告)号：WO2014042693A1
公开(公告)日：2014-03-20
申请号：PCT/US2013/032564
申请日：2013-03-15
申请人： LS9, INC. , SHUMAKER, Andrew , DA COSTA, Bernardo, M. , HOLDEN, Kevin , HOM, Louis, G. , BARON, Tarah, S. , HELMAN, Noah
发明人： SHUMAKER, Andrew , DA COSTA, Bernardo, M. , HOLDEN, Kevin , HOM, Louis, G. , BARON, Tarah, S. , HELMAN, Noah
IPC分类号： C12N9/10 , C12P7/64 , C12N1/21 , C12N1/15 , C12N9/18
CPC分类号： C12N9/18 , C12N9/1007 , C12P7/6436 , C12Y201/01015
摘要： The disclosure relates to enzyme variants with improved ester synthase properties for the production of fatty acid esters. Further contemplated are recombinant host cells that express such variants, cell cultures comprising the recombinant host cells and fatty acid ester compositions produced by such recombinant host cells.
摘要翻译：本公开涉及具有改进的用于生产脂肪酸酯的酯合成酶性质的酶变体。进一步考虑的是表达这种变体的重组宿主细胞，包含由这些重组宿主细胞产生的重组宿主细胞和脂肪酸酯组合物的细胞培养物。

8. 发明申请

WO1998012940A1 KNEE PAD 审中-公开
标题翻译：护膝
公开(公告)号：WO1998012940A1
公开(公告)日：1998-04-02
申请号：PCT/US1997016525
申请日：1997-09-18
申请人： KROLL, Michael, I. , HOLDEN, Kevin, D.
发明人： KROLL, Michael, I.
IPC分类号： A41D13/06
CPC分类号： A41D13/0562 , A41D13/0556 , A41D13/065 , Y10S2/911
摘要： A knee pad (16) for cushioning a knee of a person (18) wearing a pair of pants (20), when the person (18) is in a kneeling position. The knee pad (16) comprises a cushion member (22) being a flexible semi-cylindrical body section (24) having a flat outer surface contact area (26) with tapered sides (28) and an integral flexible quadrispherical cut back top section (30). A facility (32) is for attaching the cushion member (22) in a removable manner to a pants leg (34) of the pair of pants (20) at a knee area. When the person (18) goes into the kneeling position on a floor/ground (36), the cushion member (22) will better conform to the knee of the person (18). The flat outer surface contact area (26) will distribute weight more evenly over a wider surface area on the floor/ground (36).
摘要翻译：一种膝盖垫（16），用于当所述人（18）处于跪位时，用于缓冲穿着一条裤子（20）的人（18）的膝盖。所述膝垫（16）包括缓冲构件（22），所述缓冲构件（22）是具有平坦的外表面接触区域（26）的柔性半圆柱形主体区段（24），所述平坦的外表面接触区域具有锥形侧面（28）和整体的柔性四棱镜切割后部顶部 30）。设备（32）用于将缓冲构件（22）以可拆卸的方式附接到膝盖区域的一对裤子（20）的裤腿（34）。当人（18）进入地板/地面（36）的跪位时，缓冲构件（22）将更好地符合人（18）的膝部。平坦的外表面接触区域（26）将更均匀地分布在地板/地面（36）上较宽的表面区域上。

9. 发明申请

WO2014093505A3 ACP-MEDIATED PRODUCTION OF FATTY ACID DERIVATIVES 审中-公开
公开(公告)号：WO2014093505A3
公开(公告)日：2014-06-19
申请号：PCT/US2013/074427
申请日：2013-12-11
申请人： LS9, INC. , SIMPSON, David , DA COSTA, Bernardo , RUDE, Mathew , TRINH, Na , POPOVA, Emanuela , VENKITESWARAN, Sankaranarayanan , HELMAN, Noah , HOLDEN, Kevin
发明人： SIMPSON, David , DA COSTA, Bernardo , RUDE, Mathew , TRINH, Na , POPOVA, Emanuela , VENKITESWARAN, Sankaranarayanan , HELMAN, Noah , HOLDEN, Kevin
IPC分类号： C07K14/195 , C12N9/00 , C12P7/64
摘要： The disclosure relates to recombinant microorganisms that exhibit an increased expression of an acyl carrier protein (ACP) resulting in production of fatty acid derivatives. The disclosure further relates to methods of using the recombinant microorganisms in fermentation cultures in order to produce fatty acid derivatives and related compositions.

10. 发明申请

WO2013152051A3 IMPROVED PRODUCTION OF FATTY ACID DERIVATIVES 审中-公开
标题翻译：改进脂肪酸衍生物的生产
公开(公告)号：WO2013152051A3
公开(公告)日：2013-12-12
申请号：PCT/US2013035037
申请日：2013-04-02
申请人： LS9 INC , GREENFIELD DEREK L , SCHIRMER ANDREAS W , CLARKE ELIZABETH J , GROBAN ELI S , DA COSTA BERNARDO M , HU ZHIHAO , HOLDEN KEVIN , HELMAN NOAH
发明人： GREENFIELD DEREK L , SCHIRMER ANDREAS W , CLARKE ELIZABETH J , GROBAN ELI S , DA COSTA BERNARDO M , HU ZHIHAO , HOLDEN KEVIN , HELMAN NOAH
IPC分类号： C12N9/04 , C12N9/00 , C12N9/02 , C12N9/10 , C12N9/12 , C12N9/88 , C12N9/90 , C12P7/64
CPC分类号： C12N15/70 , C12N9/0006 , C12N9/001 , C12N9/1029 , C12N9/1288 , C12N9/88 , C12N9/90 , C12N9/93 , C12P7/04 , C12P7/6409 , C12P7/6436 , C12Y101/011 , C12Y103/01009 , C12Y103/0101 , C12Y203/01039 , C12Y203/01041 , C12Y203/01179 , C12Y203/0118 , C12Y207/08007 , C12Y402/01059 , C12Y503/03014 , C12Y604/01002
摘要： The disclosure relates to recombinant host cells including strain modifications effective to improve titer, yield and/or productivity of fatty acid derivatives. The disclosure further relates to cell cultures including the recombinant host cells for the fermentative production of fatty acid derivatives and compositions thereof.
摘要翻译：本公开涉及重组宿主细胞，其包括有效改善脂肪酸衍生物的滴度，产量和/或生产力的菌株修饰。本公开还涉及包含用于发酵生产脂肪酸衍生物及其组合物的重组宿主细胞的细胞培养物。

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