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    • 6. 发明申请
    • PYRROLYL TETRAHYDROQUINOXALIN DIONES, THEIR PRODUCTION AND USE IN THE TREATMENT OF DISEASES
    • 吡咯TETRAHYDROCHINOXALINDIONE,病害防除生产和使用
    • WO1997008168A1
    • 1997-03-06
    • PCT/EP1996003759
    • 1996-08-26
    • BASF AKTIENGESELLSCHAFTLUBISCH, WilfriedBEHL, BertholdHOFMANN, Hans-PeterTESCHENDORF, Hans-Jürgen
    • BASF AKTIENGESELLSCHAFT
    • C07D403/04
    • C07D401/14C07D403/04
    • Pyrrolyl tetrahydroquinoxalin diones of formula (I) and their tautomeric and isomeric forms, and their physiologically acceptable salts, in which the variables are: R - hydrogène, cyclohexyl radical, an aliphatic radical with 1 to 4 atoms which can bear the radical COOR , where R is hydrogen or C1-C4 alkyl, R -COOH, -COO-C1-C4, -COO-(CH2)m-Ph, -CONR R and (a), where m may be a whole number from 1 to 6, R is hydrogen, -C1-C4 alkyl or OH and R is hydrogen, -C1-C4 alkyl, -(CH2)m-Ph or (b), where all the phenyl or pyridyl rings contained in R may be substituted by up to 3 of the following radicals: -C1-C4 alkyl, halogen, -O-C1-C4 alkyl, -OCF3, -NO2, -CN, -COOR or -CONHR ; R is -CF3, -NO2, -CN and R is hydrogen; or R and R together may be an anellated benzole ring. The compounds are suitable as medicaments in human and veterinary medicine.
    • 吡咯基tetrahydrochinoxalindione的FORMUL(I)和其互变异构和异构体形式,以及它们的生理上可耐受的盐,其中各变量具有以下含义:R t <1>为氢,环己基,一个脂族基团具有1至4个碳原子,其 自由基-COOR <5>可以携带,其中R <5>是氢或C1-C4烷基,R <2> -COOH,-COO-C1-C4,-COO-(CH 2)M-PH,-CONR <6> - [R <7>和(a),其中m可以是一个整数1至6,R <6>是氢,-C 1 -C 4烷基或OH,且R <7>是氢,-C 1 -C 4 烷基, - 可以是(CH 2)米-PH或(b),其中所有本中的R苯基<2>基或吡啶基环可以被至多下列基团的至3仍然取代,-C 1 -C 4 - 烷基, 卤素,-O-C1-C4烷基,-OCF 3,-NO 2,-CN,-COOR <5>或-CONHR <5>,R <3> -CF 3,-NO 2,-CN,且R <4> <3>和R <4>可以代表稠合的苯环氢或R在一起。 该化合物适合作为药物人药和兽药。