专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2005017505A2 DIAGNOSIS OF ATOPIC DISORDER 审中-公开
标题翻译：特发性病症的诊断
公开(公告)号：WO2005017505A2
公开(公告)日：2005-02-24
申请号：PCT/GB2004/003518
申请日：2004-08-16
申请人： ISIS INNOVATION LIMITED , COOKSON, William, Osmond, Charles , MOFFAT, Miriam, Fleur , HILL, Michael, Richard , TRAHERNE, James, Arnold
发明人： COOKSON, William, Osmond, Charles , MOFFAT, Miriam, Fleur , HILL, Michael, Richard , TRAHERNE, James, Arnold
IPC分类号： G01N21/64
CPC分类号： C12Q1/6883 , C12Q2600/156 , C12Q2600/172
摘要： Detecting whether a subject has or is predisposed to an atopic disorder can be carried out by determining whether the subject has any of the identified genetic polymorphisms located in the MS4A2 gene.
摘要翻译：检测受试者是否患有或患有特应性疾病可通过确定受试者是否具有位于MS4A2基因中的任何鉴定的遗传多态性来进行。

2. 发明申请

WO2005017505A3 DIAGNOSIS OF ATOPIC DISORDER 审中-公开
标题翻译：诊断病态
公开(公告)号：WO2005017505A3
公开(公告)日：2005-06-16
申请号：PCT/GB2004003518
申请日：2004-08-16
申请人： ISIS INNOVATION , COOKSON WILLIAM OSMOND CHARLES , MOFFAT MIRIAM FLEUR , HILL MICHAEL RICHARD , TRAHERNE JAMES ARNOLD
发明人： COOKSON WILLIAM OSMOND CHARLES , MOFFAT MIRIAM FLEUR , HILL MICHAEL RICHARD , TRAHERNE JAMES ARNOLD
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/156 , C12Q2600/172
摘要： Detecting whether a subject has or is predisposed to an atopic disorder can be carried out by determining whether the subject has any of the identified genetic polymorphisms located in the MS4A2 gene.
摘要翻译：通过确定受试者是否具有位于MS4A2基因中的任何鉴定的遗传多态性，来检测受试者是否具有或倾向于特应性障碍。

3. 发明申请

WO1997008338A1 ATOPY: DIAGNOSIS AND THERAPY 审中-公开
标题翻译： ATOPY：诊断和治疗
公开(公告)号：WO1997008338A1
公开(公告)日：1997-03-06
申请号：PCT/GB1996002095
申请日：1996-08-29
申请人： ISIS INNOVATIONS LIMITED , COOKSON, William, Osmond, Charles , HILL, Michael, Richard
发明人： ISIS INNOVATIONS LIMITED
IPC分类号： C12Q01/68
CPC分类号： C12Q1/6883 , C12Q2600/156 , C12Q2600/16
摘要： The invention relates to a method for diagnosing an individual as having atopy or a predisposition thereto. The method involves demonstrating in the individual the presence or absence of either: (i) an unusual variant form of the gene which codes for the beta sub-unit of the high affinity receptor for IgE (Fc ELEMENT RI beta ), the variant form comprising a variation in exon (7) which encodes a glycine at amino acid residue 237 instead of glutamic acid which appears at residue 237 in individuals without atopy; or (ii) an unusual polymorphic form of the amino acid sequence for Fc ELEMENT RI beta , the polymorphic form comprising glycine at amino acid residue 237 instead of glutamic acid which appears at residue 237 in individuals without atopy. Materials and other methods relating to the above diagnostic method are also described.
摘要翻译：本发明涉及一种用于诊断个体具有特应性或倾向性的方法。该方法包括在个体中证明存在或不存在：（i）编码IgE（Fc ELEMENT RIβ）的高亲和力受体的β亚单位的基因的异常变体形式，所述变体形式包含在氨基酸残基237编码甘氨酸的外显子（7）的变异，而不是在没有特应性的个体中出现在残基237处的谷氨酸; 或（ii）Fc元件RIβ的氨基酸序列的异常多态形式，多态性形式包含氨基酸残基237处的甘氨酸，而不是在无特应性的个体中出现在残基237处的谷氨酸。还描述了与上述诊断方法相关的材料和其它方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式